iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061957

Ensembl Protein ID

ENSMODP00000000907.3

UniProt Accession

F6T8F3; F6T8F3_MONDO

Protein Name

Uncharacterized protein

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000755.3	ENSMODT00000000925.3	ENSMODP00000000907.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.80e-22	77.6	334	380

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 334  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 380
           8********988.6*******************.*******7.******5 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEPAPALPLA GPRPSPPGAL VAGPGPLGEF LPPPECPVFE PSWEEFADPF AFIHKIRPIA 60
EQTGICKVRP PPAWQPPFAC DVDKLHFTPR IQRLNELEAQ TRVKLNFLDQ IAKFWELQGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCGG CCCCGGCGCT GCCCCTAGCG GGCCCCCGCC CGTCTCCGCC CGGAGCACTC 60
GTCGCCGGCC CGGGCCCACT GGGCGAGTTT TTGCCTCCGC CCGAGTGCCC AGTGTTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.16	4.00e-102	367.00
IUUC-Aml-001963	Ailuropoda melanoleuca	89.03	0.00e+00	2600.00
IUUC-Apl-003770	Anas platyrhynchos	86.50	0.00e+00	2213.00
IUUC-Aca-004867	Anolis carolinensis	81.78	0.00e+00	2531.00
IUUC-Acl-008162	Aspergillus clavatus	30.07	3.00e-117	417.00
IUUC-Afl-008625	Aspergillus flavus	29.33	2.00e-112	401.00
IUUC-Afu-008796	Aspergillus fumigatus	30.88	9.00e-118	419.00
IUUC-Ani-009139	Aspergillus nidulans	31.56	2.00e-112	401.00
IUUC-Aor-010155	Aspergillus oryzae	29.33	2.00e-112	401.00
IUUC-Ame-010620	Astyanax mexicanus	63.61	0.00e+00	1960.00
IUUC-Bta-012733	Bos taurus	85.83	0.00e+00	2513.00
IUUC-Bdi-014050	Brachypodium distachyon	29.45	8.00e-121	429.00
IUUC-Bol-015336	Brassica oleracea	36.45	2.00e-14	75.90
IUUC-Cja-019050	Callithrix jacchus	89.22	0.00e+00	2696.00
IUUC-Cfa-021015	Canis familiaris	89.09	0.00e+00	2591.00
IUUC-Cpo-022340	Cavia porcellus	88.49	0.00e+00	2548.00
IUUC-Csa-023441	Chlorocebus sabaeus	89.63	0.00e+00	2684.00
IUUC-Cho-024823	Choloepus hoffmanni	91.43	0.00e+00	1618.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	30.35	6.00e-105	376.00
IUUC-Cne-026851	Cryptococcus neoformans	29.22	7.00e-114	406.00
IUUC-Dre-027707	Danio rerio	62.22	0.00e+00	1894.00
IUUC-Dno-028978	Dasypus novemcinctus	90.01	0.00e+00	2687.00
IUUC-Dor-030854	Dipodomys ordii	80.93	0.00e+00	1803.00
IUUC-Ete-032760	Echinops telfairi	86.15	0.00e+00	1758.00
IUUC-Eca-034370	Equus caballus	89.16	0.00e+00	2532.00
IUUC-Eeu-035012	Erinaceus europaeus	76.10	0.00e+00	1651.00
IUUC-Fca-035494	Felis catus	88.97	0.00e+00	2583.00
IUUC-Fal-037631	Ficedula albicollis	84.11	0.00e+00	2468.00
IUUC-Fox-037694	Fusarium oxysporum	31.88	4.00e-97	350.00
IUUC-Gmo-039522	Gadus morhua	58.73	0.00e+00	1748.00
IUUC-Ggr-039929	Gaeumannomyces graminis	27.35	2.00e-101	364.00
IUUC-Gga-040802	Gallus gallus	84.47	0.00e+00	2521.00
IUUC-Gac-041563	Gasterosteus aculeatus	61.95	0.00e+00	1880.00
IUUC-Gma-042675	Glycine max	33.58	3.00e-101	364.00
IUUC-Ggo-044856	Gorilla gorilla	72.50	0.00e+00	2008.00
IUUC-Hsa-045888	Homo sapiens	87.64	0.00e+00	2690.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	89.63	0.00e+00	2654.00
IUUC-Lch-050483	Latimeria chalumnae	66.91	0.00e+00	2067.00
IUUC-Lpe-051537	Leersia perrieri	31.32	3.00e-91	330.00
IUUC-Loc-052550	Lepisosteus oculatus	70.63	0.00e+00	2118.00
IUUC-Laf-053761	Loxodonta africana	88.22	0.00e+00	2565.00
IUUC-Mcc-055505	Macaca mulatta	87.70	0.00e+00	2691.00
IUUC-Mor-057198	Magnaporthe oryzae	28.91	3.00e-113	404.00
IUUC-Mpo-057317	Magnaporthe poae	29.03	8.00e-107	382.00
IUUC-Mga-059358	Meleagris gallopavo	83.75	0.00e+00	2477.00
IUUC-Mmr-060863	Microcebus murinus	89.18	0.00e+00	2663.00
IUUC-Mmu-063944	Mus musculus	87.74	0.00e+00	2595.00
IUUC-Mac-065069	Musa acuminata	35.14	5.00e-08	54.70
IUUC-Mpu-066719	Mustela putorius furo	87.67	0.00e+00	2651.00
IUUC-Mlu-067366	Myotis lucifugus	80.63	0.00e+00	2399.00
IUUC-Nfi-068430	Neosartorya fischeri	30.17	2.00e-115	410.00
IUUC-Ncr-068763	Neurospora crassa	31.28	5.00e-134	473.00
IUUC-Nle-069256	Nomascus leucogenys	86.72	0.00e+00	2648.00
IUUC-Ont-071756	Oreochromis niloticus	63.31	0.00e+00	1938.00
IUUC-Oan-073568	Ornithorhynchus anatinus	91.46	0.00e+00	2768.00
IUUC-Ocu-073961	Oryctolagus cuniculus	86.47	0.00e+00	2582.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	2.00e-16	81.60
IUUC-Olo-080668	Oryza longistaminata	38.83	6.00e-16	80.90
IUUC-Opu-083164	Oryza punctata	30.85	2.00e-88	321.00
IUUC-Osa-085487	Oryza sativa	38.83	2.00e-16	81.60
IUUC-Ola-086448	Oryzias latipes	60.86	0.00e+00	1854.00
IUUC-Oga-088501	Otolemur garnettii	86.75	0.00e+00	2249.00
IUUC-Oar-090162	Ovis aries	84.49	0.00e+00	2486.00
IUUC-Ptr-090816	Pan troglodytes	87.83	0.00e+00	2702.00
IUUC-Pan-092764	Papio anubis	89.76	0.00e+00	2687.00
IUUC-Psi-093918	Pelodiscus sinensis	83.64	0.00e+00	2268.00
IUUC-Pno-094879	Phaeosphaeria nodorum	30.84	3.00e-112	400.00
IUUC-Ppa-095839	Physcomitrella patens	39.81	2.00e-16	83.20
IUUC-Pfo-096672	Poecilia formosa	63.03	0.00e+00	1865.00
IUUC-Pab-097854	Pongo abelii	87.47	0.00e+00	2090.00
IUUC-Pca-100241	Procavia capensis	85.35	0.00e+00	1676.00
IUUC-Pva-103035	Pteropus vampyrus	80.18	0.00e+00	2102.00
IUUC-Pgr-103434	Puccinia graminis	33.54	4.00e-28	118.00
IUUC-Rno-105574	Rattus norvegicus	86.36	0.00e+00	2529.00
IUUC-Sce-106207	Saccharomyces cerevisiae	36.17	3.00e-76	280.00
IUUC-Sha-106552	Sarcophilus harrisii	95.34	0.00e+00	1201.00
IUUC-Sly-111298	Solanum lycopersicum	43.12	5.00e-103	370.00
IUUC-Sar-113477	Sorex araneus	85.44	0.00e+00	2305.00
IUUC-Ssc-116132	Sus scrofa	89.00	0.00e+00	2315.00
IUUC-Tgu-117452	Taeniopygia guttata	84.56	0.00e+00	2469.00
IUUC-Tru-117561	Takifugu rubripes	63.29	0.00e+00	1754.00
IUUC-Tsy-119271	Tarsius syrichta	89.54	0.00e+00	2066.00
IUUC-Tni-119650	Tetraodon nigroviridis	61.10	0.00e+00	1845.00
IUUC-Tre-122213	Trichoderma reesei	30.59	1.00e-106	382.00
IUUC-Tvi-122263	Trichoderma virens	29.89	7.00e-103	369.00
IUUC-Tae-125894	Triticum aestivum	32.65	5.00e-104	373.00
IUUC-Tur-126632	Triticum urartu	32.28	9.00e-102	365.00
IUUC-Tbe-127890	Tupaia belangeri	84.12	0.00e+00	1440.00
IUUC-Ttr-128546	Tursiops truncatus	85.08	0.00e+00	1927.00
IUUC-Uma-129590	Ustilago maydis	26.05	5.00e-123	436.00
IUUC-Vda-129733	Verticillium dahliae	29.50	2.00e-134	474.00
IUUC-Vpa-130432	Vicugna pacos	86.54	0.00e+00	1511.00
IUUC-Xtr-132008	Xenopus tropicalis	71.35	0.00e+00	2155.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence