iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049101

Ensembl Protein ID

CAY70641

UniProt Accession

C4R505; C4R505_KOMPG

Genbank Protein ID

CAY70641.1

Protein Name

F-box protein containing five copies of the WD40 motif, controls cell cycle function

Genbank Nucleotide ID

FN392321

Gene Name

PAS_chr3_0594

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr3_0594	CAY70641	CAY70641

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-48	158.5	307	343
UBD/Beta-Prp	2.70e-85	284.2	304	618

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+vtc+++ + ++l +Gs+D tik+W+l tg l++
   Q: 307  GHTDGVTCMQL-GyKILMTGSYDSTIKIWNLETGALIR 343
           8**********.5599*****************98876 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t++gh ++ +tc++   ++++l+tgs+d+tik+w+++tg l+rsl gh+ +v+++ f+++   l+tg+ D+tikv+++ tg+c++t++gh++ v+sl+f  
   Q: 304  TIEGHTDG-VTCMQL--GYKILMTGSYDSTIKIWNLETGALIRSLGGHTRGVRTLAFDDQ--KLITGGLDGTIKVFNYHTGECISTYHGHNNHVVSLDFIG 399
           66666665.566***..*******************************************..6************************************99 PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl....tgghtdsvysls.............. 187
             +++vsGs+d+t++vw++et++c+  tl+gh+++vn+v++hp++  ++s+s+D+t+r+Wdlkt+++++ +     +gh ++v++++              
   Q: 400  --KTIVSGSADQTVKVWHVETRTCY--TLRGHTDWVNSVKIHPKSMTCFSASDDTTIRMWDLKTNSCIKVFggeeNKGHVGQVQCVIplnikyeivedlek 496
           ..***********************..7***********************************************556************99999888777 PP
   S: 188  ..fdsng..................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvi 268
             f ++                   +++++ sld+t+klw+++tg+cvrt+ gh + v+s++++  + r+vsg++D++i++Wdl+sg++++t+    ssv+
   Q: 497  dnFADETreaqdsatpeteeeknypTHILTSSLDTTIKLWNVKTGKCVRTQFGHIEGVWSIAAD--TFRIVSGAHDRTIKVWDLQSGKCMHTFGSNDSSVS 595
           77444447888889999999********************************************..*****************************999999 PP
   S: 269  svavlsfgdnvlvlgsedskvniwkl 294
           +v++   gd  +++g e++k++++ +
   Q: 596  CVSL---GDTRFASGLENGKIKVYYF 618
           9999...*****************97 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MSVSEDTERC TKKPRLDDKV VFRMANQLEG KAGLEQNTDP KADKKKLSSN TDKNNNVTNF 60
LTHHVVDQSM IPRDNFHKYC YRHNPDVTCN KNTDQCKMDE IQDAMEKIPP RDREAITHVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGTAA GCGAGGACAC CGAGAGGTGT ACAAAGAAAC CGAGATTAGA CGACAAGGTT 60
GTGTTTCGAA TGGCCAATCA ATTAGAGGGC AAGGCTGGTT TGGAGCAGAA TACTGATCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0071276--P:cellular response to cadmium ion
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ppa:PAS_chr3_0594

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007794	Ashbya gossypii	54.45	7.00e-174	601.00
IUUC-Acl-008078	Aspergillus clavatus	45.06	2.00e-163	567.00
IUUC-Afl-008744	Aspergillus flavus	43.11	5.00e-150	522.00
IUUC-Afu-008939	Aspergillus fumigatus	43.85	2.00e-158	550.00
IUUC-Ani-009383	Aspergillus nidulans	44.89	7.00e-160	555.00
IUUC-Ang-009570	Aspergillus niger	45.22	1.00e-157	548.00
IUUC-Aor-010217	Aspergillus oryzae	43.11	6.00e-150	522.00
IUUC-Ate-010336	Aspergillus terreus	45.31	2.00e-156	543.00
IUUC-Bgr-012225	Blumeria graminis	43.74	5.00e-148	515.00
IUUC-Bci-013916	Botrytis cinerea	45.06	5.00e-157	545.00
IUUC-Cgl-026550	Colletotrichum gloeosporioides	45.52	2.00e-150	524.00
IUUC-Cne-026800	Cryptococcus neoformans	35.26	4.00e-85	307.00
IUUC-Dse-031413	Dothistroma septosporum	36.71	7.00e-128	449.00
IUUC-Fox-037683	Fusarium oxysporum	40.48	2.00e-129	454.00
IUUC-Fso-038092	Fusarium solani	45.67	5.00e-159	552.00
IUUC-Ggr-039842	Gaeumannomyces graminis	42.95	1.00e-151	528.00
IUUC-Lma-053200	Leptosphaeria maculans	44.32	3.00e-155	540.00
IUUC-Meu-056078	Macropus eugenii	28.86	6.00e-32	129.00
IUUC-Mor-057039	Magnaporthe oryzae	43.15	8.00e-145	505.00
IUUC-Mpo-057381	Magnaporthe poae	44.27	1.00e-152	531.00
IUUC-Mla-059099	Melampsora laricipopulina	40.18	2.00e-115	407.00
IUUC-Mvi-060426	Microbotryum violaceum	41.39	1.00e-54	206.00
IUUC-Nfi-068464	Neosartorya fischeri	44.87	1.00e-156	544.00
IUUC-Ncr-068962	Neurospora crassa	43.35	1.00e-149	521.00
IUUC-Pno-095133	Phaeosphaeria nodorum	41.67	2.00e-122	430.00
IUUC-Pgr-103527	Puccinia graminis	37.36	2.00e-64	238.00
IUUC-Ptt-103819	Puccinia triticina	32.38	2.00e-56	211.00
IUUC-Pte-104035	Pyrenophora teres	44.48	3.00e-145	506.00
IUUC-Pyt-104799	Pyrenophora triticirepentis	44.15	1.00e-144	504.00
IUUC-Sce-106343	Saccharomyces cerevisiae	55.03	0.00e+00	631.00
IUUC-Sja-107945	Schizosaccharomyces japonicus	40.72	1.00e-115	407.00
IUUC-Spo-108115	Schizosaccharomyces pombe	41.37	2.00e-114	403.00
IUUC-Sre-115173	Sporisorium reilianum	44.14	1.00e-59	223.00
IUUC-Tre-122126	Trichoderma reesei	47.04	7.00e-162	561.00
IUUC-Tvi-122482	Trichoderma virens	46.86	3.00e-161	559.00
IUUC-Tme-127212	Tuber melanosporum	45.79	9.00e-161	558.00
IUUC-Uma-129406	Ustilago maydis	44.53	9.00e-60	223.00
IUUC-Vda-129799	Verticillium dahliae	43.74	9.00e-153	531.00
IUUC-Yli-134408	Yarrowia lipolytica	48.06	1.00e-175	607.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence