iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111326

Ensembl Protein ID

Solyc11g017070.1.1

UniProt Accession

K4D6L1; K4D6L1_SOLLC

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc11g017070.1	Solyc11g017070.1.1	Solyc11g017070.1.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-25	89.4	50	89
UBD/Beta-Prp	1.90e-42	146.2	6	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH++ v+c++   d  +l++Gs D t ++WD+ tg +l++
   Q: 50   GHNGAVWCCDVsRDsSRLITGSADQTAMLWDVQTGAQLHT 89
           8***********77799******************99875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++ h+ ++t +k+ +d++ll++  +d+t +vw +++g  l ++ gh+++v++++ s+d++ l+tgs D+t+ +wd++tg ++ht++  ++ 
   Q: 6    MKGHERPLTFLKYNRDGDLLFSCAKDHTPTVWFADNGERLGTYRGHNGAVWCCDVSRDSSRLITGSADQTAMLWDVQTGAQLHTFT-FDSP 95
           55677788888888888888888888888888888888888888888888888888888888888888888888888888888888.8888 PP
   S: 97   vlslsfspsgdklvsGshdrtirv.........wdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlkt 168
           ++s++fs  gdkl++ + d    +          +        +          +l+g +g +n +v+ p ++ ++s++ D ++r+Wd +t
   Q: 96   ARSVDFSV-GDKLAVITTDPFMGLtsaihikniSK--------DpseqmsesvlVLKGPQGRINRAVWGPLNKTIISAGEDAVIRIWDAET 177
           88888888.77777777777777764444444444........14455555699************************************* PP
   S: 169  gkllrtl..tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs 241
           gk+l++   + gh++ ++sl+ + +g ++++gsld++ klwd+++ + ++ ++  + +v+ v +sp  +++v g+
   Q: 178  GKVLKESdkEIGHKKGITSLQKSVDGSHFITGSLDKSAKLWDIRSLTLIKNYTTER-PVNAVTMSPLLNHVVLGG 251
           *******98556********************************999998888654.555555555445555444 PP

Organism

Solanum lycopersicum

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR DGDLLFSCAK DHTPTVWFAD NGERLGTYRG HNGAVWCCDV 60
SRDSSRLITG SADQTAMLWD VQTGAQLHTF TFDSPARSVD FSVGDKLAVI TTDPFMGLTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCAA TATTGATGAA GGGCCATGAA AGGCCGTTAA CTTTTCTAAA GTACAACAGA 60
GATGGAGATC TGCTCTTCTC TTGCGCTAAG GACCATACCC CTACCGTTTG GTTTGCCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

sly:101262979

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	59.89	2.00e-55	208.00
IUUC-Aml-001321	Ailuropoda melanoleuca	46.93	1.00e-85	308.00
IUUC-Atr-002468	Amborella trichopoda	78.33	7.00e-95	338.00
IUUC-Apl-003841	Anas platyrhynchos	47.24	6.00e-87	313.00
IUUC-Aca-005123	Anolis carolinensis	46.63	5.00e-88	316.00
IUUC-Aly-005473	Arabidopsis lyrata	81.10	5.00e-162	562.00
IUUC-Ath-007094	Arabidopsis thaliana	80.79	3.00e-162	563.00
IUUC-Ago-008000	Ashbya gossypii	43.28	3.00e-76	277.00
IUUC-Acl-008098	Aspergillus clavatus	45.02	3.00e-78	284.00
IUUC-Afl-008494	Aspergillus flavus	45.23	4.00e-80	290.00
IUUC-Afu-009080	Aspergillus fumigatus	44.71	2.00e-78	285.00
IUUC-Ani-009230	Aspergillus nidulans	45.87	5.00e-80	290.00
IUUC-Aor-010114	Aspergillus oryzae	45.23	4.00e-80	290.00
IUUC-Ate-010285	Aspergillus terreus	46.18	9.00e-81	292.00
IUUC-Ame-011534	Astyanax mexicanus	47.42	4.00e-90	323.00
IUUC-Bgr-012121	Blumeria graminis	43.38	3.00e-75	274.00
IUUC-Bta-013143	Bos taurus	47.09	3.00e-86	310.00
IUUC-Bci-013950	Botrytis cinerea	45.15	2.00e-81	294.00
IUUC-Bdi-015019	Brachypodium distachyon	76.99	9.00e-154	535.00
IUUC-Bol-015709	Brassica oleracea	82.12	1.00e-164	572.00
IUUC-Bra-017760	Brassica rapa	82.12	6.00e-166	576.00
IUUC-Cel-018226	Caenorhabditis elegans	40.43	2.00e-71	261.00
IUUC-Cja-019741	Callithrix jacchus	47.09	2.00e-86	311.00
IUUC-Cfa-021204	Canis familiaris	46.93	2.00e-85	308.00
IUUC-Cpo-021661	Cavia porcellus	47.24	4.00e-86	310.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	50.00	6.00e-99	353.00
IUUC-Csa-024038	Chlorocebus sabaeus	47.09	2.00e-86	311.00
IUUC-Cin-025597	Ciona intestinalis	45.71	4.00e-84	303.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	45.71	4.00e-79	287.00
IUUC-Cne-026838	Cryptococcus neoformans	43.37	5.00e-80	290.00
IUUC-Cme-027304	Cyanidioschyzon merolae	53.54	9.00e-91	325.00
IUUC-Dre-028567	Danio rerio	46.79	4.00e-89	320.00
IUUC-Dno-029171	Dasypus novemcinctus	46.93	6.00e-85	307.00
IUUC-Dor-030257	Dipodomys ordii	36.16	2.00e-29	122.00
IUUC-Dse-031191	Dothistroma septosporum	45.32	1.00e-78	285.00
IUUC-Dme-031879	Drosophila melanogaster	49.85	2.00e-92	331.00
IUUC-Ete-032336	Echinops telfairi	40.09	2.00e-41	161.00
IUUC-Eca-033259	Equus caballus	46.93	2.00e-85	308.00
IUUC-Eeu-035153	Erinaceus europaeus	40.88	6.00e-24	103.00
IUUC-Fca-036489	Felis catus	46.93	2.00e-85	308.00
IUUC-Fal-037485	Ficedula albicollis	47.55	2.00e-87	314.00
IUUC-Fox-037860	Fusarium oxysporum	46.48	2.00e-80	291.00
IUUC-Fso-038188	Fusarium solani	45.87	1.00e-78	285.00
IUUC-Gmo-039311	Gadus morhua	46.32	9.00e-87	312.00
IUUC-Ggr-040045	Gaeumannomyces graminis	44.92	5.00e-78	283.00
IUUC-Gga-040645	Gallus gallus	46.27	1.00e-85	308.00
IUUC-Gac-042086	Gasterosteus aculeatus	47.09	4.00e-87	313.00
IUUC-Gma-043246	Glycine max	87.73	4.00e-175	605.00
IUUC-Ggo-045578	Gorilla gorilla	47.09	2.00e-86	311.00
IUUC-Hsa-046734	Homo sapiens	47.09	2.00e-86	311.00
IUUC-Hvu-047553	Hordeum vulgare	77.61	3.00e-154	536.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	46.93	2.00e-85	308.00
IUUC-Kpa-049325	Komagataella pastoris	46.79	4.00e-81	293.00
IUUC-Lch-049620	Latimeria chalumnae	47.51	1.00e-79	288.00
IUUC-Lpe-051338	Leersia perrieri	77.49	1.00e-145	508.00
IUUC-Loc-052094	Lepisosteus oculatus	44.27	1.00e-74	272.00
IUUC-Lma-053047	Leptosphaeria maculans	47.69	4.00e-85	307.00
IUUC-Laf-053801	Loxodonta africana	46.88	8.00e-83	299.00
IUUC-Mcc-055498	Macaca mulatta	41.90	7.00e-68	249.00
IUUC-Meu-056729	Macropus eugenii	43.77	4.00e-77	280.00
IUUC-Mor-057025	Magnaporthe oryzae	46.01	2.00e-78	285.00
IUUC-Mpo-057511	Magnaporthe poae	45.71	3.00e-78	284.00
IUUC-Mtr-058051	Medicago truncatula	88.34	3.00e-176	610.00
IUUC-Mla-059061	Melampsora laricipopulina	44.58	1.00e-78	285.00
IUUC-Mga-059229	Meleagris gallopavo	46.65	2.00e-84	305.00
IUUC-Mvi-060399	Microbotryum violaceum	44.14	2.00e-78	285.00
IUUC-Mmr-060764	Microcebus murinus	47.09	1.00e-86	312.00
IUUC-Mdo-062088	Monodelphis domestica	46.95	3.00e-86	310.00
IUUC-Mmu-064304	Mus musculus	46.79	3.00e-86	310.00
IUUC-Mac-065520	Musa acuminata	82.55	2.00e-164	570.00
IUUC-Mpu-066340	Mustela putorius furo	46.93	2.00e-85	308.00
IUUC-Mlu-067111	Myotis lucifugus	46.93	9.00e-86	309.00
IUUC-Nfi-068478	Neosartorya fischeri	45.02	2.00e-79	288.00
IUUC-Ncr-068820	Neurospora crassa	46.93	6.00e-79	286.00
IUUC-Nle-069903	Nomascus leucogenys	46.93	6.00e-86	309.00
IUUC-Opr-070221	Ochotona princeps	46.18	5.00e-84	303.00
IUUC-Ont-071765	Oreochromis niloticus	47.71	2.00e-90	324.00
IUUC-Oan-073660	Ornithorhynchus anatinus	44.52	6.00e-72	263.00
IUUC-Ocu-074039	Oryctolagus cuniculus	46.93	1.00e-85	308.00
IUUC-Oba-075395	Oryza barthii	72.39	2.00e-139	487.00
IUUC-Obr-076334	Oryza brachyantha	74.54	1.00e-145	508.00
IUUC-Ogl-077751	Oryza glaberrima	79.14	5.00e-157	546.00
IUUC-Ogu-078207	Oryza glumaepatula	78.46	5.00e-155	539.00
IUUC-Oin-079878	Oryza indica	79.14	1.00e-156	544.00
IUUC-Olo-080677	Oryza longistaminata	67.63	5.00e-147	513.00
IUUC-Ome-081228	Oryza meridionalis	62.30	3.00e-81	293.00
IUUC-Oni-082411	Oryza nivara	70.86	2.00e-133	467.00
IUUC-Opu-083136	Oryza punctata	78.83	2.00e-156	544.00
IUUC-Oru-084916	Oryza rufipogon	77.01	7.00e-155	538.00
IUUC-Osa-085776	Oryza sativa	79.14	5.00e-157	546.00
IUUC-Ola-087053	Oryzias latipes	48.17	2.00e-88	318.00
IUUC-Olu-087602	Ostreococcus lucimarinus	63.08	6.00e-124	436.00
IUUC-Oga-088154	Otolemur garnettii	46.93	7.00e-86	309.00
IUUC-Oar-089915	Ovis aries	46.93	2.00e-85	308.00
IUUC-Ptr-091124	Pan troglodytes	38.23	3.00e-57	214.00
IUUC-Pan-092035	Papio anubis	47.09	2.00e-86	311.00
IUUC-Psi-094096	Pelodiscus sinensis	44.75	3.00e-51	193.00
IUUC-Pno-094988	Phaeosphaeria nodorum	44.00	8.00e-74	269.00
IUUC-Ppa-095536	Physcomitrella patens	76.99	3.00e-154	536.00
IUUC-Pfo-096101	Poecilia formosa	47.56	3.00e-89	320.00
IUUC-Pab-097726	Pongo abelii	47.09	2.00e-86	311.00
IUUC-Pop-099617	Populus trichocarpa	85.89	1.00e-172	597.00
IUUC-Pca-101014	Procavia capensis	47.09	2.00e-86	311.00
IUUC-Ppe-101320	Prunus persica	87.73	1.00e-176	610.00
IUUC-Pva-102789	Pteropus vampyrus	43.43	6.00e-75	273.00
IUUC-Pgr-103479	Puccinia graminis	44.17	2.00e-79	288.00
IUUC-Ptt-103981	Puccinia triticina	43.56	9.00e-79	286.00
IUUC-Pte-104278	Pyrenophora teres	46.46	7.00e-82	296.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	46.46	7.00e-82	296.00
IUUC-Rno-105867	Rattus norvegicus	43.90	3.00e-69	254.00
IUUC-Sce-106251	Saccharomyces cerevisiae	41.44	5.00e-72	263.00
IUUC-Sha-107039	Sarcophilus harrisii	46.95	5.00e-86	310.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	46.50	8.00e-85	306.00
IUUC-Spo-108314	Schizosaccharomyces pombe	46.01	2.00e-85	308.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	44.55	2.00e-80	291.00
IUUC-Smo-108728	Selaginella moellendorffii	75.69	3.00e-151	526.00
IUUC-Sit-110801	Setaria italica	77.91	8.00e-154	535.00
IUUC-Stu-112458	Solanum tuberosum	97.24	0.00e+00	662.00
IUUC-Sbi-114063	Sorghum bicolor	76.38	2.00e-152	530.00
IUUC-Sre-115096	Sporisorium reilianum	42.43	5.00e-72	263.00
IUUC-Ssc-116080	Sus scrofa	47.09	3.00e-86	310.00
IUUC-Tgu-116988	Taeniopygia guttata	47.55	3.00e-87	314.00
IUUC-Tru-118766	Takifugu rubripes	47.71	9.00e-90	322.00
IUUC-Tni-120197	Tetraodon nigroviridis	48.01	2.00e-90	324.00
IUUC-Tca-121316	Theobroma cacao	87.42	1.00e-174	604.00
IUUC-Tre-122097	Trichoderma reesei	46.79	2.00e-80	291.00
IUUC-Tvi-122442	Trichoderma virens	46.48	3.00e-80	291.00
IUUC-Tae-125800	Triticum aestivum	77.61	2.00e-154	537.00
IUUC-Tur-126334	Triticum urartu	69.02	2.00e-129	454.00
IUUC-Tme-127038	Tuber melanosporum	46.32	3.00e-84	304.00
IUUC-Ttr-128659	Tursiops truncatus	44.34	9.00e-67	246.00
IUUC-Uma-129464	Ustilago maydis	42.43	1.00e-72	265.00
IUUC-Vda-129841	Verticillium dahliae	46.63	8.00e-80	289.00
IUUC-Vvi-131076	Vitis vinifera	87.42	2.00e-175	606.00
IUUC-Xtr-132395	Xenopus tropicalis	48.32	5.00e-89	320.00
IUUC-Xma-133383	Xiphophorus maculatus	47.56	4.00e-89	320.00
IUUC-Yli-134586	Yarrowia lipolytica	45.43	9.00e-73	266.00
IUUC-Zma-135904	Zea mays	76.69	4.00e-153	533.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence