iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066869

Ensembl Protein ID

ENSMPUP00000001055.1

UniProt Accession

M3XPQ5; M3XPQ5_MUSPF

Genbank Protein ID

ENSMPUP00000001055

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01069331

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000001063.1	ENSMPUT00000001076.1	ENSMPUP00000001055.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-55	182.4	293	331
UBD/Beta-Prp	1.30e-64	218.2	163	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 293  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 331
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
             +v++ ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h++++++++
   Q: 163  ALDVDW-QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIK 250
           444555.6666677777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 102  fsp.........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           +sp         s+  l+s+s d+t+r+wd+e g c + tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+
   Q: 251  WSPtgpatsnpnSNIMLASASFDSTVRLWDVERGVCTH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TG 336
           77655555544333567777777777777777777777.7777777777777777777777777777777777777777777776..77 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlq 210
            +  + ++  g  + + + dg+v + dl+
   Q: 337  GIFEVCWNARGDKVGASASDGSVCVLDLR 365
           77777777777777777777777776665 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MEIDGDVEIP PNKATVLRGH ESEVFICAWN PVSDLLASGS GDSTARIWNL NENSNGGSTQ 60
LVLRHCIREG GHDVPSNKDV TSLDWNSDGT LLATGSYDGF ARIWTEDGNL ASTLGQHKGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAATAG ACGGGGACGT TGAGATCCCG CCCAACAAAG CCACAGTCCT CCGGGGCCAC 60
GAGTCGGAGG TGTTCATCTG TGCCTGGAAC CCTGTCAGCG ATCTCCTCGC TTCAGGGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.45	0.00e+00	756.00
IUUC-Loc-052722	Lepisosteus oculatus	95.36	0.00e+00	736.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence