iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059958

UUCD1 version

UUC-MeG-00825

Ensembl Protein ID

ENSMGAP00000003293.2

UniProt Accession

G1MWX5; G1MWX5_MELGA

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003535.2	ENSMGAT00000003992.2	ENSMGAP00000003293.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	4.80e-113	377.7	1	253

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 15   PglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyA 103
           Pglftllvedfgvk++ qvee+y+L++++    q+pv+g+++lFk++e+r+s+rk+++++++++v+d+di++++ffa+q+i+NsCat+A
   Q: 1    PGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QGPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNNMFFAHQLIPNSCATHA 84
           9***************.************....******************************************************** PP
   S: 104  llsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlye 192
           llsvllnc+++  dlG+tlsr+k++tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q++ ++++t+eafhfvsyv+i+grl+e
   Q: 85   LLSVLLNCNNV--DLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLFE 171
           *********99..**************************************************************************** PP
   S: 193  ldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkidkeLlkLlkdieseee 274
           ldglk++P+d+g++ ++ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk+++  + +l++++ ++ 
   Q: 172  LDGLKVYPIDHGPWADDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRMKYESKLHILKMNR--QTVLEALQQLIR 253
           ****************************..*****************************************9..555555555554 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

PGLFTLLVED FGVKGVQVEE IYDLQSKCQG PVYGFIFLFK WIEERRSRRK VSTLVDETSV 60
IDDDIVNNMF FAHQLIPNSC ATHALLSVLL NCNNVDLGPT LSRMKDFTKG FSPESKGYAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGTCTCT TCACACTCCT GGTCGAAGAT TTTGGTGAGT CCAAGGCACC TTCCTGGGAA 60
GCTGACTTCA TGCTTGGCAT TACCTCCAGC TCTTTGTGGT GGGCTTCTTA CCAGCTTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	92.88	6.00e-146	510.00
IUUC-Apl-003405	Anas platyrhynchos	96.08	2.00e-45	176.00
IUUC-Aca-004836	Anolis carolinensis	84.38	1.00e-162	566.00
IUUC-Ame-011946	Astyanax mexicanus	79.29	2.00e-145	509.00
IUUC-Bta-013131	Bos taurus	83.33	8.00e-129	453.00
IUUC-Cja-019599	Callithrix jacchus	86.44	7.00e-150	523.00
IUUC-Cfa-021003	Canis familiaris	83.91	2.00e-143	502.00
IUUC-Cpo-022143	Cavia porcellus	87.58	2.00e-147	515.00
IUUC-Csa-023477	Chlorocebus sabaeus	87.91	3.00e-148	518.00
IUUC-Cho-024734	Choloepus hoffmanni	78.57	2.00e-43	170.00
IUUC-Csv-025842	Ciona savignyi	61.24	2.00e-89	322.00
IUUC-Dre-027793	Danio rerio	78.40	2.00e-145	509.00
IUUC-Dno-029253	Dasypus novemcinctus	87.58	4.00e-148	518.00
IUUC-Dor-030891	Dipodomys ordii	74.18	5.00e-122	431.00
IUUC-Dme-031796	Drosophila melanogaster	61.15	1.00e-88	319.00
IUUC-Ete-032646	Echinops telfairi	90.44	1.00e-124	439.00
IUUC-Eca-033805	Equus caballus	88.56	4.00e-149	521.00
IUUC-Eeu-035216	Erinaceus europaeus	72.58	2.00e-69	256.00
IUUC-Fca-035611	Felis catus	95.77	2.00e-143	502.00
IUUC-Fal-037186	Ficedula albicollis	94.84	1.00e-132	466.00
IUUC-Gmo-038824	Gadus morhua	80.06	2.00e-149	522.00
IUUC-Gga-040875	Gallus gallus	99.34	1.00e-173	602.00
IUUC-Gac-042226	Gasterosteus aculeatus	82.03	4.00e-149	521.00
IUUC-Ggo-045122	Gorilla gorilla	85.49	2.00e-148	519.00
IUUC-Hsa-045882	Homo sapiens	87.25	2.00e-147	515.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	95.77	4.00e-144	504.00
IUUC-Lch-049960	Latimeria chalumnae	71.90	2.00e-124	439.00
IUUC-Loc-052408	Lepisosteus oculatus	91.07	1.00e-150	525.00
IUUC-Laf-054187	Loxodonta africana	95.38	9.00e-154	536.00
IUUC-Mcc-055273	Macaca mulatta	87.46	1.00e-141	496.00
IUUC-Meu-056267	Macropus eugenii	97.06	3.00e-142	498.00
IUUC-Mmr-061280	Microcebus murinus	95.77	6.00e-144	504.00
IUUC-Mdo-062625	Monodelphis domestica	85.80	5.00e-164	570.00
IUUC-Mmu-063853	Mus musculus	84.29	2.00e-147	516.00
IUUC-Mlu-067771	Myotis lucifugus	86.93	2.00e-147	516.00
IUUC-Opr-070741	Ochotona princeps	83.38	2.00e-150	526.00
IUUC-Ont-072172	Oreochromis niloticus	80.00	9.00e-149	520.00
IUUC-Oan-073167	Ornithorhynchus anatinus	85.45	3.00e-164	571.00
IUUC-Ocu-074176	Oryctolagus cuniculus	87.58	5.00e-143	501.00
IUUC-Ola-087203	Oryzias latipes	84.98	1.00e-127	449.00
IUUC-Oga-089153	Otolemur garnettii	85.44	5.00e-147	514.00
IUUC-Oar-090008	Ovis aries	88.89	8.00e-150	523.00
IUUC-Ptr-091234	Pan troglodytes	87.58	5.00e-148	517.00
IUUC-Pan-092005	Papio anubis	87.91	3.00e-148	518.00
IUUC-Psi-093995	Pelodiscus sinensis	87.85	2.00e-163	568.00
IUUC-Pma-094110	Petromyzon marinus	87.30	4.00e-64	238.00
IUUC-Pfo-097418	Poecilia formosa	80.25	5.00e-148	517.00
IUUC-Pab-098267	Pongo abelii	87.91	2.00e-148	519.00
IUUC-Pca-101084	Procavia capensis	87.91	1.00e-158	552.00
IUUC-Pva-102292	Pteropus vampyrus	88.27	6.00e-149	520.00
IUUC-Rno-105251	Rattus norvegicus	81.40	3.00e-145	508.00
IUUC-Sha-107100	Sarcophilus harrisii	84.85	9.00e-162	563.00
IUUC-Sar-113559	Sorex araneus	94.09	4.00e-118	418.00
IUUC-Ssc-115688	Sus scrofa	82.48	6.00e-148	517.00
IUUC-Tgu-117424	Taeniopygia guttata	94.25	6.00e-172	597.00
IUUC-Tru-118585	Takifugu rubripes	82.15	5.00e-145	507.00
IUUC-Tsy-119299	Tarsius syrichta	68.52	2.00e-107	382.00
IUUC-Tni-120808	Tetraodon nigroviridis	80.39	2.00e-146	512.00
IUUC-Tbe-127705	Tupaia belangeri	93.85	8.00e-135	472.00
IUUC-Ttr-128225	Tursiops truncatus	87.91	1.00e-147	516.00
IUUC-Uma-129391	Ustilago maydis	29.03	2.30e+00	26.60
IUUC-Vpa-130193	Vicugna pacos	76.54	5.00e-94	338.00
IUUC-Xtr-132449	Xenopus tropicalis	91.76	9.00e-152	530.00
IUUC-Xma-133232	Xiphophorus maculatus	79.00	1.00e-146	513.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence