iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044996

UUCD1 version

UUC-GoG-00653

Ensembl Protein ID

ENSGGOP00000016344.2

UniProt Accession

G3RKR6; G3RKR6_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000016756.2	ENSGGOT00000016808.2	ENSGGOP00000016344.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.80e-07	30.6	18	56
E3 activity/RING/U-box	8.70e-06	26.1	15	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v pCgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSPCGHRFCDTCLQEF-----LSEGVFKCPE 56
           **********999*************999.....89*******6 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
            +lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l
   Q: 15   RLLCPLCGKPMREPVQVSpCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPEL 72
           689************8888*****************99*********99999998776 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSPCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLGLP IRCIHSEEGC RWSGPLRHLQ GHLNTCSFNV IPCPNRCPMK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGGAGCCC GGAGCGCCGC TCCAGCGAGG CGCGGGCTGT GGGGCCGCCG CGTGCCTGGC 60
CCCGCTCGCC CGTGCCGGCC GCTCGCCCGC CATGCCTGGC TTCGACTACA AGTTCCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

KEGG

ggo:101142858

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	96.16	0.00e+00	894.00
IUUC-Ani-009190	Aspergillus nidulans	25.33	3.00e-12	66.60
IUUC-Ame-011530	Astyanax mexicanus	77.45	0.00e+00	773.00
IUUC-Bta-013582	Bos taurus	97.66	0.00e+00	916.00
IUUC-Cja-019883	Callithrix jacchus	94.79	1.00e-51	194.00
IUUC-Cfa-020133	Canis familiaris	91.49	0.00e+00	845.00
IUUC-Cpo-022021	Cavia porcellus	98.09	0.00e+00	922.00
IUUC-Csa-023199	Chlorocebus sabaeus	98.94	0.00e+00	928.00
IUUC-Dre-028193	Danio rerio	76.60	0.00e+00	768.00
IUUC-Dno-028917	Dasypus novemcinctus	98.09	0.00e+00	922.00
IUUC-Ete-032433	Echinops telfairi	97.66	0.00e+00	917.00
IUUC-Fca-036155	Felis catus	97.66	0.00e+00	917.00
IUUC-Fox-037935	Fusarium oxysporum	27.27	2.00e-14	73.90
IUUC-Gmo-038860	Gadus morhua	77.45	0.00e+00	771.00
IUUC-Gga-041052	Gallus gallus	80.64	0.00e+00	823.00
IUUC-Gac-041489	Gasterosteus aculeatus	77.23	0.00e+00	769.00
IUUC-Hsa-046252	Homo sapiens	99.79	0.00e+00	934.00
IUUC-Hvu-047127	Hordeum vulgare	36.71	2.00e-07	49.70
IUUC-Itr-048232	Ictidomys tridecemlineatus	98.51	0.00e+00	924.00
IUUC-Kpa-049340	Komagataella pastoris	26.46	7.00e-16	78.60
IUUC-Lpe-051100	Leersia perrieri	38.57	8.00e-08	50.80
IUUC-Loc-052312	Lepisosteus oculatus	77.07	0.00e+00	766.00
IUUC-Lma-053014	Leptosphaeria maculans	22.01	3.00e-13	69.70
IUUC-Laf-054376	Loxodonta africana	98.09	0.00e+00	920.00
IUUC-Mcc-055684	Macaca mulatta	98.94	0.00e+00	928.00
IUUC-Mmr-061198	Microcebus murinus	98.51	0.00e+00	924.00
IUUC-Mdo-062585	Monodelphis domestica	86.60	0.00e+00	827.00
IUUC-Mmu-064303	Mus musculus	96.60	0.00e+00	912.00
IUUC-Mac-064529	Musa acuminata	29.60	3.00e-09	56.20
IUUC-Mpu-066854	Mustela putorius furo	97.23	0.00e+00	913.00
IUUC-Nle-070098	Nomascus leucogenys	98.30	0.00e+00	922.00
IUUC-Ont-071518	Oreochromis niloticus	77.40	0.00e+00	770.00
IUUC-Ocu-073841	Oryctolagus cuniculus	98.30	0.00e+00	923.00
IUUC-Ola-086674	Oryzias latipes	77.19	0.00e+00	768.00
IUUC-Oga-088510	Otolemur garnettii	98.09	0.00e+00	921.00
IUUC-Oar-089225	Ovis aries	94.47	0.00e+00	878.00
IUUC-Pan-092725	Papio anubis	98.94	0.00e+00	928.00
IUUC-Pfo-096341	Poecilia formosa	77.19	0.00e+00	771.00
IUUC-Pva-103131	Pteropus vampyrus	98.47	2.00e-142	498.00
IUUC-Rno-105996	Rattus norvegicus	96.81	0.00e+00	912.00
IUUC-Sly-111800	Solanum lycopersicum	30.00	1.00e-05	46.20
IUUC-Sre-115218	Sporisorium reilianum	23.83	2.00e-10	61.20
IUUC-Tru-117602	Takifugu rubripes	77.45	0.00e+00	774.00
IUUC-Tur-126067	Triticum urartu	40.51	1.00e-08	53.50
IUUC-Ttr-128370	Tursiops truncatus	97.86	0.00e+00	722.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence