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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Rno-104871
Ensembl Protein ID ENSRNOP00000059807.2
UniProt Accession D3ZRU9; D3ZRU9_RAT
Genbank Protein ID ENSRNOP00000059807
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AABR07067427
Gene Name Rev1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000018623.6 ENSRNOT00000067197.2 ENSRNOP00000059807.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 1.00e-21 76.2 1011 1039
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
    ++sqvDp Vf++LP+e+Q+E++a+++q++
   Q: 1011 AFSQVDPDVFAALPAELQKELKAAYDQRQ 1039
    59*************************98 PP
   

Organism Rattus norvegicus
Functional Description
(View)

Functional Description



     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRGGWRKRA EEDGWEKWGG YMAAKVQKLE EQFRSDAAKQ KDGTASAIFS GVAIYVNGYT 60
DPSAEELRNL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Rno-104871|UBD,UBM|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACCGGCTTCC TCCCTCCTGC CTTGCTCTCA GGGACCCCGG AAGCAGTGTG TTCCTCGCTC 60
CTTTTCCCTT GTTACTTATC TGTCCCTTCC GTGTGCAGGA CACCTGTCCC CAAGTGTCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Rno-104871|UBD,UBM|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 28.39 3.00e-31 130.00
IUUC-Aml-001185 Ailuropoda melanoleuca 79.09 0.00e+00 1946.00
IUUC-Atr-002915 Amborella trichopoda 30.11 4.00e-102 366.00
IUUC-Apl-004054 Anas platyrhynchos 71.47 0.00e+00 1686.00
IUUC-Aca-004304 Anolis carolinensis 65.70 0.00e+00 1556.00
IUUC-Aly-005696 Arabidopsis lyrata 34.46 1.00e-85 311.00
IUUC-Ath-006893 Arabidopsis thaliana 35.50 3.00e-87 317.00
IUUC-Ago-007722 Ashbya gossypii 28.91 3.00e-40 160.00
IUUC-Acl-008347 Aspergillus clavatus 34.66 2.00e-84 307.00
IUUC-Afl-008444 Aspergillus flavus 34.13 2.00e-86 314.00
IUUC-Afu-008837 Aspergillus fumigatus 31.46 2.00e-86 314.00
IUUC-Ani-009188 Aspergillus nidulans 30.12 2.00e-88 320.00
IUUC-Ang-009866 Aspergillus niger 33.71 9.00e-97 348.00
IUUC-Aor-010107 Aspergillus oryzae 34.13 2.00e-86 313.00
IUUC-Ate-010359 Aspergillus terreus 32.16 1.00e-93 338.00
IUUC-Ame-010664 Astyanax mexicanus 49.52 0.00e+00 1116.00
IUUC-Bgr-012244 Blumeria graminis 31.21 5.00e-83 302.00
IUUC-Bta-013405 Bos taurus 74.90 0.00e+00 1688.00
IUUC-Bci-013849 Botrytis cinerea 30.05 9.00e-84 305.00
IUUC-Bdi-014066 Brachypodium distachyon 32.79 4.00e-82 300.00
IUUC-Bol-015544 Brassica oleracea 31.05 4.00e-87 316.00
IUUC-Bra-017792 Brassica rapa 33.56 3.00e-82 300.00
IUUC-Cel-018148 Caenorhabditis elegans 36.57 2.00e-81 297.00
IUUC-Cja-019742 Callithrix jacchus 70.00 0.00e+00 1398.00
IUUC-Cfa-020112 Canis familiaris 79.97 0.00e+00 1961.00
IUUC-Cpo-022152 Cavia porcellus 80.98 0.00e+00 1998.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 30.42 7.00e-50 192.00
IUUC-Csa-023504 Chlorocebus sabaeus 81.02 0.00e+00 1982.00
IUUC-Cho-024780 Choloepus hoffmanni 65.35 0.00e+00 716.00
IUUC-Cin-025276 Ciona intestinalis 41.34 4.00e-112 399.00
IUUC-Csv-026283 Ciona savignyi 44.06 2.00e-112 400.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 28.16 5.00e-88 319.00
IUUC-Cne-027079 Cryptococcus neoformans 34.52 8.00e-78 285.00
IUUC-Cme-027346 Cyanidioschyzon merolae 27.17 1.00e-44 175.00
IUUC-Dre-028073 Danio rerio 50.19 0.00e+00 1085.00
IUUC-Dno-030038 Dasypus novemcinctus 77.01 0.00e+00 1858.00
IUUC-Dor-031100 Dipodomys ordii 77.82 0.00e+00 1422.00
IUUC-Dse-031310 Dothistroma septosporum 27.61 9.00e-82 298.00
IUUC-Dme-031991 Drosophila melanogaster 41.87 3.00e-110 393.00
IUUC-Ete-033082 Echinops telfairi 69.35 0.00e+00 1272.00
IUUC-Eca-033471 Equus caballus 80.02 0.00e+00 1946.00
IUUC-Eeu-034993 Erinaceus europaeus 78.93 0.00e+00 1326.00
IUUC-Fca-035367 Felis catus 79.28 0.00e+00 1851.00
IUUC-Fal-036973 Ficedula albicollis 71.57 0.00e+00 1646.00
IUUC-Fox-037677 Fusarium oxysporum 29.70 1.00e-83 305.00
IUUC-Fso-038252 Fusarium solani 28.48 6.00e-90 325.00
IUUC-Gmo-039669 Gadus morhua 50.54 2.00e-171 596.00
IUUC-Ggr-039988 Gaeumannomyces graminis 29.05 4.00e-84 306.00
IUUC-Gga-040423 Gallus gallus 71.60 0.00e+00 1684.00
IUUC-Gac-042134 Gasterosteus aculeatus 51.09 0.00e+00 802.00
IUUC-Gma-042929 Glycine max 32.81 2.00e-111 397.00
IUUC-Ggo-044528 Gorilla gorilla 80.86 0.00e+00 1980.00
IUUC-Hsa-046259 Homo sapiens 80.70 0.00e+00 1959.00
IUUC-Hvu-047139 Hordeum vulgare 34.66 6.00e-56 211.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 81.12 0.00e+00 1998.00
IUUC-Kpa-049169 Komagataella pastoris 30.24 6.00e-61 229.00
IUUC-Lch-050471 Latimeria chalumnae 63.48 0.00e+00 1474.00
IUUC-Lpe-050800 Leersia perrieri 30.51 3.00e-88 320.00
IUUC-Loc-052320 Lepisosteus oculatus 46.45 0.00e+00 926.00
IUUC-Lma-053149 Leptosphaeria maculans 30.33 1.00e-87 318.00
IUUC-Laf-053810 Loxodonta africana 75.32 0.00e+00 1764.00
IUUC-Mcc-055574 Macaca mulatta 80.62 0.00e+00 1948.00
IUUC-Meu-055945 Macropus eugenii 59.68 0.00e+00 1035.00
IUUC-Mor-057195 Magnaporthe oryzae 30.17 8.00e-89 322.00
IUUC-Mpo-057488 Magnaporthe poae 34.54 5.00e-84 306.00
IUUC-Mtr-057955 Medicago truncatula 35.88 5.00e-89 322.00
IUUC-Mla-059027 Melampsora laricipopulina 32.54 3.00e-79 290.00
IUUC-Mga-060156 Meleagris gallopavo 71.51 0.00e+00 1692.00
IUUC-Mvi-060398 Microbotryum violaceum 34.92 7.00e-80 292.00
IUUC-Mmr-061113 Microcebus murinus 80.89 0.00e+00 1947.00
IUUC-Mdo-063001 Monodelphis domestica 75.22 0.00e+00 1818.00
IUUC-Mmu-063180 Mus musculus 90.65 0.00e+00 2202.00
IUUC-Mac-065551 Musa acuminata 35.93 5.00e-52 199.00
IUUC-Mpu-066525 Mustela putorius furo 79.25 0.00e+00 1946.00
IUUC-Mlu-067877 Myotis lucifugus 79.28 0.00e+00 1905.00
IUUC-Nfi-068418 Neosartorya fischeri 31.64 1.00e-87 318.00
IUUC-Ncr-068648 Neurospora crassa 32.18 3.00e-87 317.00
IUUC-Nle-069959 Nomascus leucogenys 81.74 0.00e+00 1969.00
IUUC-Opr-070522 Ochotona princeps 77.04 0.00e+00 1115.00
IUUC-Ont-072293 Oreochromis niloticus 46.87 0.00e+00 806.00
IUUC-Oan-073519 Ornithorhynchus anatinus 72.85 0.00e+00 1763.00
IUUC-Ocu-074492 Oryctolagus cuniculus 78.92 0.00e+00 1788.00
IUUC-Oba-075567 Oryza barthii 30.63 2.00e-88 320.00
IUUC-Obr-076332 Oryza brachyantha 35.88 5.00e-84 306.00
IUUC-Ogl-077348 Oryza glaberrima 30.63 1.00e-88 321.00
IUUC-Ogu-078779 Oryza glumaepatula 30.49 6.00e-88 319.00
IUUC-Oin-079738 Oryza indica 28.59 8.00e-77 282.00
IUUC-Olo-080701 Oryza longistaminata 28.51 1.00e-76 281.00
IUUC-Ome-081708 Oryza meridionalis 32.59 1.00e-85 311.00
IUUC-Oni-082251 Oryza nivara 30.46 2.00e-85 310.00
IUUC-Opu-083528 Oryza punctata 31.55 7.00e-80 292.00
IUUC-Oru-084293 Oryza rufipogon 30.08 1.00e-83 305.00
IUUC-Osa-085549 Oryza sativa 30.63 3.00e-88 320.00
IUUC-Ola-086793 Oryzias latipes 46.63 0.00e+00 1013.00
IUUC-Olu-087786 Ostreococcus lucimarinus 29.04 6.00e-60 225.00
IUUC-Oga-089006 Otolemur garnettii 80.33 0.00e+00 1938.00
IUUC-Oar-089597 Ovis aries 75.38 0.00e+00 1828.00
IUUC-Ptr-091520 Pan troglodytes 80.78 0.00e+00 1960.00
IUUC-Pan-092333 Papio anubis 80.86 0.00e+00 1939.00
IUUC-Psi-094004 Pelodiscus sinensis 72.58 0.00e+00 1719.00
IUUC-Pma-094128 Petromyzon marinus 54.84 3.00e-94 339.00
IUUC-Pno-094849 Phaeosphaeria nodorum 29.07 1.00e-80 295.00
IUUC-Ppa-095714 Physcomitrella patens 28.70 3.00e-95 343.00
IUUC-Pfo-096569 Poecilia formosa 49.94 0.00e+00 771.00
IUUC-Pab-097960 Pongo abelii 80.38 0.00e+00 1951.00
IUUC-Pop-098921 Populus trichocarpa 35.85 5.00e-82 299.00
IUUC-Pca-100509 Procavia capensis 62.19 0.00e+00 1082.00
IUUC-Ppe-101730 Prunus persica 29.91 2.00e-91 330.00
IUUC-Pva-102142 Pteropus vampyrus 78.18 0.00e+00 1892.00
IUUC-Pgr-103446 Puccinia graminis 31.46 2.00e-70 260.00
IUUC-Ptt-103849 Puccinia triticina 30.83 3.00e-75 278.00
IUUC-Pte-104128 Pyrenophora teres 29.70 2.00e-85 311.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 32.66 3.00e-83 303.00
IUUC-Sce-106236 Saccharomyces cerevisiae 27.22 2.00e-38 154.00
IUUC-Sha-106962 Sarcophilus harrisii 75.28 0.00e+00 1813.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 32.15 2.00e-61 231.00
IUUC-Spo-108170 Schizosaccharomyces pombe 28.77 7.00e-63 235.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 27.50 8.00e-107 382.00
IUUC-Smo-109554 Selaginella moellendorffii 37.27 1.00e-85 311.00
IUUC-Sit-110479 Setaria italica 35.06 6.00e-71 262.00
IUUC-Sly-111752 Solanum lycopersicum 31.65 9.00e-90 325.00
IUUC-Sar-113304 Sorex araneus 77.90 0.00e+00 1855.00
IUUC-Sbi-114196 Sorghum bicolor 35.28 2.00e-72 268.00
IUUC-Sre-115151 Sporisorium reilianum 31.40 7.00e-84 306.00
IUUC-Ssc-116104 Sus scrofa 78.38 0.00e+00 1898.00
IUUC-Tgu-117438 Taeniopygia guttata 71.67 0.00e+00 1677.00
IUUC-Tru-118553 Takifugu rubripes 48.27 0.00e+00 997.00
IUUC-Tsy-119056 Tarsius syrichta 75.44 0.00e+00 1764.00
IUUC-Tni-119933 Tetraodon nigroviridis 47.97 0.00e+00 961.00
IUUC-Tca-121376 Theobroma cacao 29.44 2.00e-106 381.00
IUUC-Tre-121972 Trichoderma reesei 27.55 2.00e-79 291.00
IUUC-Tvi-122342 Trichoderma virens 31.31 5.00e-80 293.00
IUUC-Tae-123898 Triticum aestivum 31.53 5.00e-88 319.00
IUUC-Tur-126735 Triticum urartu 29.55 9.00e-36 145.00
IUUC-Tme-126999 Tuber melanosporum 33.60 2.00e-80 294.00
IUUC-Tbe-127280 Tupaia belangeri 76.66 1.00e-117 418.00
IUUC-Ttr-129104 Tursiops truncatus 77.82 0.00e+00 1883.00
IUUC-Uma-129562 Ustilago maydis 30.83 1.00e-86 315.00
IUUC-Vda-129862 Verticillium dahliae 31.02 1.00e-87 318.00
IUUC-Vpa-130819 Vicugna pacos 77.57 0.00e+00 1020.00
IUUC-Vvi-131111 Vitis vinifera 31.66 3.00e-110 393.00
IUUC-Xtr-132629 Xenopus tropicalis 58.80 0.00e+00 1337.00
IUUC-Xma-134065 Xiphophorus maculatus 47.44 1.00e-168 587.00
IUUC-Yli-134633 Yarrowia lipolytica 34.14 3.00e-65 243.00
IUUC-Zma-135176 Zea mays 32.19 1.00e-86 314.00
Created Date 25-Jun-2017

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