iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067693

Ensembl Protein ID

ENSMLUP00000006479.2

UniProt Accession

G1P8H6; G1P8H6_MYOLU

Genbank Protein ID

ENSMLUP00000006479

Protein Name

Anoctamin

Genbank Nucleotide ID

AAPE02023390

Gene Name

ANO6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007076.2	ENSMLUT00000007096.2	ENSMLUP00000006479.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	25.64	2.10e-01	29.30	IUUC-Ots-000008

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

EEFNGKPNSL YFNDGQRRID FVLVYEDESR KENNKKGANE KQRRKRRAYE SNLIHDGLQL 60
EATRSVLDDK LVFVKIHAPW EVLCTYAELM HIKLPLKPND LKTRSSAFDN FNWLGKVLQR 120

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Nucleotide Sequence
(Fasta)

GAAGAATTTA ATGGGAAACC CAACTCACTC TATTTTAATG ACGGCCAGCG AAGAATCGAC 60
TTTGTTCTAG TGTATGAAGA TGAAAGTAGA AAAGAGAACA ATAAAAAGGG TGCAAATGAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR032394--Anoct_dimer
IPR007632--Anoctamin
IPR031295--Anoctamin-6

Pfam

PF16178--Anoct_dimer
PF04547--Anoctamin

Gene Ontology

GO:0009986--C:cell surface
GO:0034707--C:chloride channel complex
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0005227--F:calcium activated cation channel activity
GO:0005229--F:intracellular calcium activated chloride channel activity
GO:0017128--F:phospholipid scramblase activity
GO:0005247--F:voltage-gated chloride channel activity
GO:0002543--P:activation of blood coagulation via clotting cascade
GO:0032060--P:bleb assembly
GO:0007596--P:blood coagulation
GO:0035630--P:bone mineralization involved in bone maturation
GO:0061591--P:calcium activated galactosylceramide scrambling
GO:0061590--P:calcium activated phosphatidylcholine scrambling
GO:0061589--P:calcium activated phosphatidylserine scrambling
GO:0070588--P:calcium ion transmembrane transport
GO:0002407--P:dendritic cell chemotaxis
GO:0045794--P:negative regulation of cell volume
GO:0097045--P:phosphatidylserine exposure on blood platelet
GO:0046931--P:pore complex assembly
GO:0030501--P:positive regulation of bone mineralization
GO:2000353--P:positive regulation of endothelial cell apoptotic process
GO:0034767--P:positive regulation of ion transmembrane transport
GO:0090026--P:positive regulation of monocyte chemotaxis
GO:0060100--P:positive regulation of phagocytosis, engulfment
GO:0035590--P:purinergic nucleotide receptor signaling pathway
GO:0035725--P:sodium ion transmembrane transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Lma-053282	Leptosphaeria maculans	25.42	1.50e+00	28.10
IUUC-Ttr-129015	Tursiops truncatus	86.01	0.00e+00	1441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence