iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066479

Ensembl Protein ID

ENSMPUP00000010546.1

UniProt Accession

M3YGT9; M3YGT9_MUSPF

Genbank Protein ID

ENSMPUP00000010546

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AEYP01019344

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010625.1	ENSMPUT00000010716.1	ENSMPUP00000010546.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.50e-09	35.9	273	320

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 273  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 320
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLSPANGEQV HLVNYVEDYL DSIESLPFDL QRSVSLMREI DAKYQGTVVW SVFRRRSAAA 60
AAEGAEVPGA PQDTRLVRQA GAVPAGGGGS VDRGLRWGSL RDTCRCAEIL KELDEYYEKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNG CCGGCGGGCG GGAGCTTTGC ATTTTGCAGC GCTGGGCTCC GAGGGGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	100.00	7.00e-110	389.00
IUUC-Apl-003910	Anas platyrhynchos	93.56	2.00e-101	362.00
IUUC-Aca-004874	Anolis carolinensis	93.59	2.00e-101	362.00
IUUC-Ame-011262	Astyanax mexicanus	67.35	7.00e-77	280.00
IUUC-Bta-013507	Bos taurus	91.45	4.00e-93	333.00
IUUC-Bol-015245	Brassica oleracea	81.82	2.00e-28	119.00
IUUC-Cja-018925	Callithrix jacchus	89.32	1.00e-97	349.00
IUUC-Cfa-020947	Canis familiaris	99.15	6.00e-108	383.00
IUUC-Cpo-022286	Cavia porcellus	93.19	9.00e-102	363.00
IUUC-Csa-023825	Chlorocebus sabaeus	88.89	4.00e-97	347.00
IUUC-Cho-024577	Choloepus hoffmanni	95.28	3.00e-103	367.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.00
IUUC-Dno-029834	Dasypus novemcinctus	95.30	6.00e-105	373.00
IUUC-Dor-030315	Dipodomys ordii	89.79	2.00e-103	368.00
IUUC-Ete-032408	Echinops telfairi	93.13	4.00e-98	351.00
IUUC-Eca-034244	Equus caballus	97.01	1.00e-105	375.00
IUUC-Fca-035391	Felis catus	97.72	4.00e-100	357.00
IUUC-Fal-036838	Ficedula albicollis	92.74	5.00e-101	360.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	2.00e-19	90.10
IUUC-Gga-040619	Gallus gallus	92.31	1.00e-100	358.00
IUUC-Gac-041996	Gasterosteus aculeatus	62.29	6.00e-71	260.00
IUUC-Ggo-045481	Gorilla gorilla	88.46	1.00e-96	346.00
IUUC-Hsa-046170	Homo sapiens	88.46	9.00e-97	347.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	96.58	4.00e-106	377.00
IUUC-Lch-050397	Latimeria chalumnae	88.03	6.00e-97	346.00
IUUC-Loc-052038	Lepisosteus oculatus	82.27	5.00e-83	300.00
IUUC-Laf-054126	Loxodonta africana	95.30	3.00e-105	374.00
IUUC-Mcc-055031	Macaca mulatta	88.46	8.00e-97	347.00
IUUC-Meu-056248	Macropus eugenii	95.28	2.00e-102	365.00
IUUC-Mga-059217	Meleagris gallopavo	92.27	8.00e-100	356.00
IUUC-Mmr-061581	Microcebus murinus	94.87	6.00e-104	369.00
IUUC-Mdo-062452	Monodelphis domestica	94.87	3.00e-103	367.00
IUUC-Mmu-063412	Mus musculus	94.02	3.00e-103	367.00
IUUC-Mlu-067723	Myotis lucifugus	97.87	5.00e-107	380.00
IUUC-Nle-069122	Nomascus leucogenys	88.46	2.00e-96	345.00
IUUC-Opr-070835	Ochotona princeps	86.70	2.00e-85	308.00
IUUC-Oan-073023	Ornithorhynchus anatinus	91.03	7.00e-98	350.00
IUUC-Ocu-073779	Oryctolagus cuniculus	91.10	2.00e-96	345.00
IUUC-Ola-086891	Oryzias latipes	64.53	6.00e-72	263.00
IUUC-Olu-087851	Ostreococcus lucimarinus	69.23	2.00e-19	89.00
IUUC-Oga-087954	Otolemur garnettii	94.44	1.00e-103	369.00
IUUC-Oar-090006	Ovis aries	91.88	5.00e-99	353.00
IUUC-Ptr-090589	Pan troglodytes	88.89	3.00e-97	347.00
IUUC-Pan-091896	Papio anubis	88.46	4.00e-97	348.00
IUUC-Psi-093266	Pelodiscus sinensis	94.02	9.00e-103	366.00
IUUC-Pma-094265	Petromyzon marinus	75.34	2.00e-33	134.00
IUUC-Pfo-097531	Poecilia formosa	59.46	1.00e-69	256.00
IUUC-Pab-098253	Pongo abelii	88.89	5.00e-97	347.00
IUUC-Pva-102753	Pteropus vampyrus	93.59	2.00e-94	339.00
IUUC-Rno-105964	Rattus norvegicus	93.16	6.00e-92	330.00
IUUC-Sha-107270	Sarcophilus harrisii	94.02	1.00e-101	362.00
IUUC-Tgu-116822	Taeniopygia guttata	93.16	2.00e-101	362.00
IUUC-Tni-119980	Tetraodon nigroviridis	59.23	1.00e-70	259.00
IUUC-Tvi-122341	Trichoderma virens	62.50	4.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	90.48	1.00e-103	369.00
IUUC-Uma-129581	Ustilago maydis	57.14	5.00e-21	96.30
IUUC-Xtr-132200	Xenopus tropicalis	83.76	7.00e-89	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence