iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028172

UUCD1 version

UUC-DaR-01242

Ensembl Protein ID

ENSDARP00000076693.3

UniProt Accession

Q6P0D9; B0S611; Q803C8; CIAO1_DANRE

Genbank Protein ID

CAQ13300.1; AAH44534.1; AAH65658.1; AAI71538.1; AAI71540.1

Protein Name

Probable cytosolic iron-sulfur protein assembly protein ciao1; WD repeat-containing protein 39

Genbank Nucleotide ID

BX323451; BC044534; BC065658; BC171538; BC171540

Gene Name

ciao1; wdr39; si:dkey-49H9.1; zgc:55911; zgc:77394

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000059212.3	ENSDART00000082256.3	ENSDARP00000076693.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-40	134.2	192	222
UBD/Beta-Prp	4.50e-56	191.1	54	273

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++ v++l f ++ ++l+s+sdD t+k+W 
   Q: 192  GHESTVWSLTFdPEgRRLASCSDDRTVKIWK 222
           8***********9999**************5 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls...tgkc 86
           ++l++ h+  +++v++sp +++la++s d+t+ +w+ t++++  l  l+ghe+ev++v + p+g++l+t+s+D+ + +w+++    ++c
   Q: 54   CVLSDGHQRTVRKVAWSPCGKYLASASFDATTCIWKKTDEDFecLTVLEGHENEVKCVAWAPSGSLLATCSRDKSVWIWEVDeedEYEC 142
           7888999999999***************************99989999*******************************8777779*** PP
   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl........ 166
           +++++ h+++v  + ++p+++ l+s+s d+ i +++ e + +    tl+gh+++v++++++p+g+ l+s+s+Drtv++W+         
   Q: 143  LSVVNSHTQDVKHVVWHPTQELLASASYDNKICIYKEEDDDWECRaTLEGHESTVWSLTFDPEGRRLASCSDDRTVKIWKEsttgdgss 231
           ***********************************99887665545**********************************9******** PP
   S: 167  .ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
            ++ k++ tl+g h + +y +++ +    l+++  d  v+++
   Q: 232  dESWKCICTLSGFHGRTIYDIAWCRLTGALATACGDDGVRVF 273
           **********************99999899888888888876 PP

Organism

Danio rerio

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MKGALELQHR VSAHPDSRCW YVAWNPAGTT LATCGGDRAI RIWGKEGDSW ECKCVLSDGH 60
QRTVRKVAWS PCGKYLASAS FDATTCIWKK TDEDFECLTV LEGHENEVKC VAWAPSGSLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTATCAACCG CAAGACACTG AAGCACAAAA CAGGAAGCGG GAAGCAGCTG ATAAACAGAA 60
GACTTGAAGT TGTGTGACAT CCGAGAGAGA ACAGTGCTGC CGACAGGGAA ACATTTACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

KEGG

dre:795104

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	51.50	3.00e-69	256.00
IUUC-Aml-001317	Ailuropoda melanoleuca	76.35	6.00e-143	500.00
IUUC-Atr-003029	Amborella trichopoda	49.71	5.00e-89	321.00
IUUC-Apl-004042	Anas platyrhynchos	56.82	5.00e-39	152.00
IUUC-Aly-005812	Arabidopsis lyrata	48.08	4.00e-82	298.00
IUUC-Ath-006671	Arabidopsis thaliana	48.27	3.00e-83	301.00
IUUC-Ago-007820	Ashbya gossypii	42.26	1.00e-57	217.00
IUUC-Acl-008042	Aspergillus clavatus	30.23	2.00e-45	176.00
IUUC-Afl-008639	Aspergillus flavus	32.53	1.00e-49	191.00
IUUC-Afu-008899	Aspergillus fumigatus	33.81	4.00e-44	172.00
IUUC-Ani-009453	Aspergillus nidulans	30.53	9.00e-44	171.00
IUUC-Ang-009758	Aspergillus niger	40.32	4.00e-42	165.00
IUUC-Aor-010212	Aspergillus oryzae	32.53	1.00e-49	191.00
IUUC-Ate-010314	Aspergillus terreus	31.34	3.00e-45	176.00
IUUC-Ame-010676	Astyanax mexicanus	84.94	2.00e-170	591.00
IUUC-Bgr-012095	Blumeria graminis	30.83	5.00e-35	142.00
IUUC-Bta-012884	Bos taurus	75.00	7.00e-143	499.00
IUUC-Bci-013622	Botrytis cinerea	31.30	3.00e-36	146.00
IUUC-Bdi-014614	Brachypodium distachyon	48.28	4.00e-86	311.00
IUUC-Bol-016439	Brassica oleracea	46.65	9.00e-80	290.00
IUUC-Bra-016830	Brassica rapa	46.90	9.00e-80	290.00
IUUC-Cel-018709	Caenorhabditis elegans	39.29	4.00e-66	244.00
IUUC-Cja-019822	Callithrix jacchus	76.35	2.00e-142	498.00
IUUC-Cfa-020823	Canis familiaris	76.35	1.00e-142	499.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	45.53	3.00e-76	278.00
IUUC-Csa-023754	Chlorocebus sabaeus	76.95	3.00e-143	501.00
IUUC-Cin-025395	Ciona intestinalis	54.35	6.00e-103	367.00
IUUC-Csv-025943	Ciona savignyi	51.04	5.00e-100	357.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	30.05	2.00e-34	140.00
IUUC-Cne-026939	Cryptococcus neoformans	29.41	8.00e-44	171.00
IUUC-Cme-027239	Cyanidioschyzon merolae	39.83	1.00e-41	164.00
IUUC-Dno-029472	Dasypus novemcinctus	76.74	5.00e-121	427.00
IUUC-Dor-031134	Dipodomys ordii	66.47	8.00e-117	413.00
IUUC-Dse-031535	Dothistroma septosporum	27.76	2.00e-41	163.00
IUUC-Dme-032020	Drosophila melanogaster	57.83	8.00e-113	400.00
IUUC-Eca-033700	Equus caballus	76.65	1.00e-143	502.00
IUUC-Eeu-035010	Erinaceus europaeus	73.95	1.00e-138	485.00
IUUC-Fca-036309	Felis catus	68.96	3.00e-134	471.00
IUUC-Fal-037243	Ficedula albicollis	64.65	7.00e-75	273.00
IUUC-Fox-038058	Fusarium oxysporum	33.68	5.00e-41	162.00
IUUC-Fso-038459	Fusarium solani	35.12	2.00e-36	147.00
IUUC-Gmo-039375	Gadus morhua	80.79	6.00e-150	523.00
IUUC-Ggr-040002	Gaeumannomyces graminis	34.27	1.00e-37	150.00
IUUC-Gga-040294	Gallus gallus	66.56	6.00e-106	377.00
IUUC-Gac-042499	Gasterosteus aculeatus	76.51	2.00e-142	498.00
IUUC-Gma-043543	Glycine max	47.23	5.00e-87	314.00
IUUC-Ggo-045181	Gorilla gorilla	76.95	3.00e-143	501.00
IUUC-Hsa-046528	Homo sapiens	76.95	3.00e-143	501.00
IUUC-Hvu-047341	Hordeum vulgare	56.35	2.00e-57	214.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	76.65	9.00e-143	499.00
IUUC-Kpa-049353	Komagataella pastoris	36.62	4.00e-52	198.00
IUUC-Lch-049763	Latimeria chalumnae	72.54	1.00e-141	496.00
IUUC-Lpe-051500	Leersia perrieri	45.26	4.00e-85	308.00
IUUC-Loc-052021	Lepisosteus oculatus	75.52	1.00e-139	488.00
IUUC-Lma-053331	Leptosphaeria maculans	31.02	9.00e-49	189.00
IUUC-Laf-054558	Loxodonta africana	76.65	2.00e-143	501.00
IUUC-Mcc-055374	Macaca mulatta	76.95	3.00e-142	498.00
IUUC-Meu-056042	Macropus eugenii	64.11	2.00e-87	315.00
IUUC-Mor-057187	Magnaporthe oryzae	33.77	3.00e-34	139.00
IUUC-Mtr-058072	Medicago truncatula	46.61	3.00e-85	308.00
IUUC-Mla-059108	Melampsora laricipopulina	30.91	1.00e-48	187.00
IUUC-Mga-059370	Meleagris gallopavo	53.12	6.00e-79	287.00
IUUC-Mvi-060495	Microbotryum violaceum	35.34	5.00e-52	198.00
IUUC-Mmr-060902	Microcebus murinus	76.95	1.00e-143	502.00
IUUC-Mdo-062510	Monodelphis domestica	75.45	8.00e-137	479.00
IUUC-Mmu-063575	Mus musculus	75.75	1.00e-141	496.00
IUUC-Mac-065322	Musa acuminata	49.57	1.00e-91	329.00
IUUC-Mpu-065925	Mustela putorius furo	76.35	3.00e-143	501.00
IUUC-Mlu-067755	Myotis lucifugus	76.05	2.00e-142	498.00
IUUC-Nfi-068327	Neosartorya fischeri	30.52	1.00e-43	170.00
IUUC-Ncr-068845	Neurospora crassa	32.92	2.00e-29	123.00
IUUC-Nle-069406	Nomascus leucogenys	74.55	4.00e-137	480.00
IUUC-Opr-070416	Ochotona princeps	84.05	2.00e-67	249.00
IUUC-Ont-071936	Oreochromis niloticus	80.18	4.00e-148	517.00
IUUC-Oan-073452	Ornithorhynchus anatinus	73.33	2.00e-56	211.00
IUUC-Ocu-074791	Oryctolagus cuniculus	76.05	4.00e-142	497.00
IUUC-Oba-075636	Oryza barthii	49.85	1.00e-89	323.00
IUUC-Obr-076742	Oryza brachyantha	49.82	9.00e-78	283.00
IUUC-Ogl-077766	Oryza glaberrima	49.85	1.00e-89	323.00
IUUC-Ogu-079039	Oryza glumaepatula	49.85	5.00e-90	324.00
IUUC-Oin-079315	Oryza indica	50.17	1.00e-77	283.00
IUUC-Olo-080669	Oryza longistaminata	44.42	6.00e-82	298.00
IUUC-Ome-081490	Oryza meridionalis	49.85	6.00e-90	324.00
IUUC-Oni-082572	Oryza nivara	49.85	1.00e-89	323.00
IUUC-Opu-083732	Oryza punctata	50.44	1.00e-90	326.00
IUUC-Oru-084763	Oryza rufipogon	49.85	1.00e-89	323.00
IUUC-Osa-085372	Oryza sativa	49.85	1.00e-89	323.00
IUUC-Ola-087379	Oryzias latipes	77.25	5.00e-143	500.00
IUUC-Olu-087801	Ostreococcus lucimarinus	33.52	8.00e-42	164.00
IUUC-Oga-089076	Otolemur garnettii	76.65	1.00e-143	502.00
IUUC-Oar-090022	Ovis aries	76.35	2.00e-145	508.00
IUUC-Ptr-090809	Pan troglodytes	76.95	3.00e-143	501.00
IUUC-Pan-091685	Papio anubis	76.95	1.00e-144	506.00
IUUC-Psi-093046	Pelodiscus sinensis	73.65	6.00e-139	487.00
IUUC-Pma-094181	Petromyzon marinus	62.69	3.00e-125	441.00
IUUC-Pno-094882	Phaeosphaeria nodorum	34.42	3.00e-48	186.00
IUUC-Ppa-095172	Physcomitrella patens	46.33	1.00e-80	293.00
IUUC-Pfo-096396	Poecilia formosa	77.06	1.00e-145	509.00
IUUC-Pab-098427	Pongo abelii	76.35	2.00e-140	491.00
IUUC-Pop-100016	Populus trichocarpa	50.00	3.00e-91	328.00
IUUC-Pca-101048	Procavia capensis	76.95	4.00e-144	504.00
IUUC-Ppe-102050	Prunus persica	47.56	2.00e-86	312.00
IUUC-Pva-103117	Pteropus vampyrus	76.05	2.00e-143	501.00
IUUC-Pgr-103307	Puccinia graminis	33.18	3.00e-53	202.00
IUUC-Ptt-103938	Puccinia triticina	38.73	3.00e-47	182.00
IUUC-Pte-104315	Pyrenophora teres	32.11	1.00e-50	194.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	31.62	4.00e-50	192.00
IUUC-Rno-105523	Rattus norvegicus	76.35	8.00e-143	499.00
IUUC-Sce-106297	Saccharomyces cerevisiae	45.34	3.00e-62	231.00
IUUC-Sha-106981	Sarcophilus harrisii	76.04	5.00e-115	407.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	38.30	2.00e-55	210.00
IUUC-Spo-108214	Schizosaccharomyces pombe	43.01	6.00e-60	225.00
IUUC-Smo-109034	Selaginella moellendorffii	45.15	4.00e-83	301.00
IUUC-Sit-110663	Setaria italica	49.86	3.00e-91	328.00
IUUC-Sly-110898	Solanum lycopersicum	47.89	1.00e-80	293.00
IUUC-Stu-112647	Solanum tuberosum	51.14	6.00e-70	257.00
IUUC-Sbi-114288	Sorghum bicolor	48.99	1.00e-87	316.00
IUUC-Sre-115065	Sporisorium reilianum	39.57	9.00e-67	247.00
IUUC-Ssc-115960	Sus scrofa	70.54	7.00e-144	503.00
IUUC-Tru-118382	Takifugu rubripes	77.41	6.00e-153	533.00
IUUC-Tsy-119585	Tarsius syrichta	68.86	3.00e-124	437.00
IUUC-Tni-120133	Tetraodon nigroviridis	77.27	2.00e-144	504.00
IUUC-Tca-121167	Theobroma cacao	47.55	3.00e-82	298.00
IUUC-Tre-122119	Trichoderma reesei	29.27	2.00e-38	153.00
IUUC-Tvi-122407	Trichoderma virens	28.90	3.00e-38	152.00
IUUC-Tae-125748	Triticum aestivum	48.99	3.00e-85	308.00
IUUC-Tur-126682	Triticum urartu	51.50	5.00e-71	260.00
IUUC-Tme-127095	Tuber melanosporum	36.01	8.00e-58	217.00
IUUC-Tbe-128004	Tupaia belangeri	76.65	6.00e-143	500.00
IUUC-Ttr-129284	Tursiops truncatus	73.59	6.00e-137	480.00
IUUC-Uma-129527	Ustilago maydis	39.68	6.00e-67	248.00
IUUC-Vda-129854	Verticillium dahliae	31.54	2.00e-35	143.00
IUUC-Vpa-130681	Vicugna pacos	86.21	7.00e-44	170.00
IUUC-Vvi-131004	Vitis vinifera	50.89	8.00e-87	313.00
IUUC-Xtr-131928	Xenopus tropicalis	72.12	2.00e-135	475.00
IUUC-Xma-134290	Xiphophorus maculatus	75.84	5.00e-142	497.00
IUUC-Yli-134364	Yarrowia lipolytica	41.98	4.00e-63	235.00
IUUC-Zma-135658	Zea mays	48.68	4.00e-87	315.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence