iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-027026

Ensembl Protein ID

AAW44790

UniProt Accession

Q5KDE6; Q55Q21; Q5KDE6_CRYNJ

Genbank Protein ID

AAW44790.1

Protein Name

Ubiquitin-protein ligase, putative

Genbank Nucleotide ID

AE017347

Gene Name

CNG04260

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNG04260	AAW44790	AAW44790

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	7.80e-79	264.4	76	710

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 17   keyeelytavynlclsk..vgaklYkklkevleefikqvkkkvee...sedeqlLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlw 112
            +y+ +    ++++l++  ++ +l +k    +  + + ++++ +    ++d + L ++ + W+ ++     l +++ +ld++y +  ++ +  r+ a+ ++
   Q: 76   LSYQHITAFCQTVVLQDrdAASQLSDKCTSSIDRYTEIIRRELKGgilAKDRNTLGKLCESWQVWTARTTLLSSLLVHLDKVYHSSFSEPNILRSRAIAKF 176
           55544444444445544888999999999999999877766655422256888********************************9555544455555555 PP
   S: 113  rkeived..ikkrllelllklieaeRkgeav..drrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqe.....nevdeYlkkvearl 204
           +  + +d  i++ +++ + +   +eR+  +   +r  +  v +    L    +++++    +++ ++t+ +y+    + ++e     ++  eY     a++
   Q: 177  KSIVWQDsvIHAVIIDDIFRWLSEERQTGIPssARPTILAVDKIAQTL----QTFGE--LAIAYQDETHDYYTSALRNAVSEieqgkRKAGEYAPWFLAKM 271
           5555555555559*************9876511334444444443333....33333..34688999999998765544433211247899********** PP
   S: 205  neeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerl 304
            eee+r++++ ++ t++ L++ + k+  ++  ++++   +++ + +++ +  s++y+     ++    l+k+le+++++ +++++++++++     ++ + 
   Q: 272  VEEENRVRECFHTFTLQLLARDLRKVGQSETTDKVIeLAVEQAMSNDEAKGFSELYHFS-IETDKFASLVKSLENYLAKRVSTLISDPVNDPR---MIDET 368
           *****************************999999866788888888999999999864.45568999************************9...***** PP
   S: 305  lelknklqklvseaFnndakFlkaldkafetfvnknsvlka...................................aksp.EllAryiDqlLrksskglte 369
           l+lk   +k vs++F+++ +     d++++ +  +++  +                                     ++p E +A++ D  +rk+ +  te
   Q: 369  LKLKRFAEKTVSNLFSEEDTEPLPADEDVKMISVEEKEEREkekeaakekrqsvrmrmfeleeavrsgfktgmgsrQNAPaEWIAKHLDAAMRKGQGSGTE 469
           *****************9999999999999876665444446899*****************************9977788******************** PP
   S: 370  eeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFk..eekenteesesvelsv 468
           e+ +++ld++++++ + ++kdvF+++Y + LakRLl++ksas+++E+ ++ kL++e g efts    M++dl++Se+l r ++  + +  ++  e  +++ 
   Q: 470  EQFNNHLDEIVTLIGFTKDKDVFKAFYSSQLAKRLLLNKSASNDQEKTMVAKLQKELGEEFTSG-DVMMKDLQLSETLVRSYQlaQSRGPAQYGETSNFTA 569
           **************************************************************97.99*************99955666667778999**** PP
   S: 469  lvLsagaWpta...setekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpee 566
           +vL+++aWp +    +  +++L++ l+ +i++f++ Y  +h+ R L+W  +l++++l+a +  g+ye+ Vs fQ++vLL++n+ e++++ e+k+ t+++++
   Q: 570  NVLTESAWPAYpllKDGWNFHLTPSLQSSIDDFTSWYTTQHKNRVLSWRFQLATVTLTARFPSGRYEVGVSLFQAVVLLLYNEIESLTFAEIKERTGIENN 670
           ***********76444478********************************************************************************** PP
   S: 567  eLrrtlqsLvssk..kqvlkkepeskeieeedlfsvNqef 604
           eL rtlqsL+ ++   +vl k+p +ke++ +d+f  N+ f
   Q: 671  ELVRTLQSLALGRkgTRVLLKKPSGKEVNPTDIFAWNKGF 710
           ***********87799*********************987 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MSSLVVFPST TNAFTSYRPS VRAHVDFIKP GSGSQHSTGR IVKLELPSLV QPQATDQLEP 60
LFKSIDAILA GQPTPLSYQH ITAFCQTVVL QDRDAASQLS DKCTSSIDRY TEIIRRELKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACCAGCTC TCGACCTGCA ACTGTCCCGA ACTTCACAAT GTCCTCTCTC GTGGTGTTCC 60
CGTCTACAAC AAATGCATTC ACCTCTTACA GGCCAAGTGT AAGAGCGCAC GTCGACTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0016874--F:ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cne:CNG04260

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008359	Aspergillus clavatus	26.55	2.00e-59	222.00
IUUC-Afl-008567	Aspergillus flavus	28.39	5.00e-73	267.00
IUUC-Afu-008833	Aspergillus fumigatus	27.89	5.00e-67	247.00
IUUC-Ani-009373	Aspergillus nidulans	38.29	9.00e-67	246.00
IUUC-Ang-009622	Aspergillus niger	28.41	2.00e-70	258.00
IUUC-Aor-010241	Aspergillus oryzae	28.70	5.00e-73	267.00
IUUC-Ate-010251	Aspergillus terreus	28.06	1.00e-71	262.00
IUUC-Cel-018369	Caenorhabditis elegans	33.50	8.00e-54	203.00
IUUC-Cin-025727	Ciona intestinalis	34.58	4.00e-81	293.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	37.82	2.00e-64	238.00
IUUC-Ggr-040003	Gaeumannomyces graminis	37.06	4.00e-55	207.00
IUUC-Mla-058936	Melampsora laricipopulina	38.07	2.00e-61	228.00
IUUC-Mvi-060455	Microbotryum violaceum	43.62	4.00e-79	287.00
IUUC-Nfi-068363	Neosartorya fischeri	28.43	4.00e-70	257.00
IUUC-Pca-100391	Procavia capensis	41.71	6.00e-68	249.00
IUUC-Pgr-103334	Puccinia graminis	36.69	7.00e-59	220.00
IUUC-Ptt-103903	Puccinia triticina	39.18	7.00e-61	226.00
IUUC-Pte-104167	Pyrenophora teres	33.96	5.00e-61	227.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	34.12	1.00e-59	222.00
IUUC-Sce-106354	Saccharomyces cerevisiae	27.59	3.00e-33	134.00
IUUC-Sja-107940	Schizosaccharomyces japonicus	26.95	6.00e-65	240.00
IUUC-Spo-108109	Schizosaccharomyces pombe	33.42	1.00e-53	202.00
IUUC-Sar-112956	Sorex araneus	41.99	5.00e-71	260.00
IUUC-Sre-114943	Sporisorium reilianum	33.91	2.00e-74	272.00
IUUC-Tsy-119517	Tarsius syrichta	40.98	2.00e-70	258.00
IUUC-Tre-121907	Trichoderma reesei	38.20	4.00e-65	241.00
IUUC-Tvi-122568	Trichoderma virens	35.35	4.00e-65	241.00
IUUC-Ttr-129112	Tursiops truncatus	41.24	5.00e-77	280.00
IUUC-Uma-129531	Ustilago maydis	32.09	4.00e-67	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence