iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091198

UUCD1 version

UUC-PaT-00067

Ensembl Protein ID

ENSPTRP00000028384.4

UniProt Accession

G2HFK3; G2HFK3_PANTR

Genbank Protein ID

BAK62511.1; JAA10785.1; JAA10786.1; JAA24068.1

Protein Name

Pleiotropic regulator 1

Genbank Nucleotide ID

AACZ03034446; GABC01000553; GABC01000552; GABD01009032

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000016533.5	ENSPTRT00000030732.4	ENSPTRP00000028384.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-44	146.4	202	238
UBD/Beta-Prp	4.10e-64	216.6	297	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 202  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 238
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
           +p  ++l+t srd+t ++wdv+t+  +++lsgh+++v++v+++  ++ ++tgs D ti++wdl +gk+ +tl++h++sv+++ ++p  +
   Q: 297  HPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHY 385
           44445566666666666666666666666666666666666666666666666666666666666666666666666666666666666 PP
   S: 108  klvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.......tgghtdsvyslsfd 189
           +++sGs d+ i+ w+ + g+ ++  lsgh++++n+++v++ + +lvsG++++t+ lWd +tg   ++        + + ++ +   +fd
   Q: 386  TFASGSPDN-IKQWKFPDGSFIQ-NLSGHNAIINTLTVNS-DGVLVSGADNGTMHLWDWRTGYNFQRVhaavqpgSLDSESGIFACAFD 471
           666666443.5666666666666.6666666666666666.445566666666666666666555555443333322233333344466 PP
   S: 190  sngkelvsgsldgtvklwd 208
           ++  +l+++  d+t+k++ 
   Q: 472  QSESRLLTAEADKTIKVYR 490
           6666666666666666654 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADNG KPVPLDEESH KRKMAIKLRN EYGPVLHMPT 60
SKENLKEKGP QNATDSYVHK QYPANQGQEV EYFVAGTHPY PPGPGVALTA DTKIQRMPSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGCTTGCA TCACATCCGC CGCCTGGGCG CCCAAGTCCG GAAGGTGCTG CACAGCTGTG 60
GCGGCGGGTA CTGCGTTAGT GATTAGAGTT TCTTCCCTGC CGGAGGTGGG ATACACGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus

KEGG

ptr:461557

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	47.18	3.00e-129	455.00
IUUC-Aml-001605	Ailuropoda melanoleuca	96.30	0.00e+00	1032.00
IUUC-Atr-002757	Amborella trichopoda	48.98	5.00e-129	454.00
IUUC-Apl-003198	Anas platyrhynchos	89.34	0.00e+00	961.00
IUUC-Aca-004683	Anolis carolinensis	88.57	0.00e+00	946.00
IUUC-Aly-005775	Arabidopsis lyrata	59.94	1.00e-125	442.00
IUUC-Ath-007460	Arabidopsis thaliana	53.07	2.00e-125	442.00
IUUC-Ago-007884	Ashbya gossypii	46.49	6.00e-108	384.00
IUUC-Acl-008153	Aspergillus clavatus	64.02	2.00e-128	452.00
IUUC-Afl-008384	Aspergillus flavus	64.63	3.00e-129	455.00
IUUC-Afu-009045	Aspergillus fumigatus	64.63	3.00e-129	454.00
IUUC-Ani-009229	Aspergillus nidulans	62.32	3.00e-129	454.00
IUUC-Ang-009812	Aspergillus niger	65.30	1.00e-123	435.00
IUUC-Aor-010059	Aspergillus oryzae	64.63	3.00e-129	455.00
IUUC-Ate-010351	Aspergillus terreus	62.79	1.00e-135	476.00
IUUC-Ame-011613	Astyanax mexicanus	58.76	1.00e-154	539.00
IUUC-Bgr-012042	Blumeria graminis	50.55	3.00e-135	474.00
IUUC-Bta-012406	Bos taurus	95.34	0.00e+00	1019.00
IUUC-Bci-013760	Botrytis cinerea	61.73	3.00e-134	471.00
IUUC-Bdi-014776	Brachypodium distachyon	50.64	6.00e-131	460.00
IUUC-Bol-016189	Brassica oleracea	53.17	3.00e-126	445.00
IUUC-Bra-018044	Brassica rapa	53.17	3.00e-126	444.00
IUUC-Cel-018651	Caenorhabditis elegans	53.71	5.00e-156	543.00
IUUC-Cja-019974	Callithrix jacchus	99.03	0.00e+00	1065.00
IUUC-Cfa-021085	Canis familiaris	95.92	0.00e+00	1033.00
IUUC-Cpo-021458	Cavia porcellus	96.12	0.00e+00	1032.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.57	9.00e-124	436.00
IUUC-Csa-023883	Chlorocebus sabaeus	99.61	0.00e+00	1070.00
IUUC-Cho-024623	Choloepus hoffmanni	94.31	0.00e+00	996.00
IUUC-Cin-025190	Ciona intestinalis	60.51	0.00e+00	644.00
IUUC-Csv-026367	Ciona savignyi	60.08	0.00e+00	655.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	56.96	1.00e-139	489.00
IUUC-Cne-027069	Cryptococcus neoformans	63.44	6.00e-127	447.00
IUUC-Cme-027233	Cyanidioschyzon merolae	30.18	5.00e-35	141.00
IUUC-Dre-028260	Danio rerio	78.10	0.00e+00	836.00
IUUC-Dno-029112	Dasypus novemcinctus	96.50	0.00e+00	1043.00
IUUC-Dor-031118	Dipodomys ordii	94.88	0.00e+00	803.00
IUUC-Dse-031493	Dothistroma septosporum	46.48	8.00e-127	447.00
IUUC-Dme-032138	Drosophila melanogaster	76.62	4.00e-160	557.00
IUUC-Ete-032411	Echinops telfairi	83.37	0.00e+00	832.00
IUUC-Eca-033521	Equus caballus	95.34	0.00e+00	1029.00
IUUC-Eeu-035249	Erinaceus europaeus	81.22	0.00e+00	660.00
IUUC-Fca-036358	Felis catus	95.34	0.00e+00	1028.00
IUUC-Fal-036933	Ficedula albicollis	89.73	0.00e+00	961.00
IUUC-Fox-037713	Fusarium oxysporum	56.42	8.00e-139	486.00
IUUC-Fso-038380	Fusarium solani	63.45	1.00e-138	486.00
IUUC-Gmo-039133	Gadus morhua	78.36	0.00e+00	833.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.36	2.00e-132	465.00
IUUC-Gga-041176	Gallus gallus	88.37	0.00e+00	955.00
IUUC-Gac-042344	Gasterosteus aculeatus	76.55	0.00e+00	828.00
IUUC-Gma-043328	Glycine max	49.80	2.00e-133	468.00
IUUC-Ggo-044478	Gorilla gorilla	99.61	0.00e+00	1069.00
IUUC-Hsa-046037	Homo sapiens	99.81	0.00e+00	1070.00
IUUC-Hvu-047349	Hordeum vulgare	50.51	3.00e-133	468.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	97.09	0.00e+00	1045.00
IUUC-Kpa-049343	Komagataella pastoris	58.46	8.00e-119	420.00
IUUC-Lch-049830	Latimeria chalumnae	83.72	0.00e+00	899.00
IUUC-Lpe-051442	Leersia perrieri	49.59	2.00e-129	456.00
IUUC-Loc-051794	Lepisosteus oculatus	81.69	0.00e+00	851.00
IUUC-Lma-053137	Leptosphaeria maculans	44.83	5.00e-127	447.00
IUUC-Laf-053471	Loxodonta africana	95.52	0.00e+00	1022.00
IUUC-Mcc-055627	Macaca mulatta	99.42	0.00e+00	1068.00
IUUC-Meu-056148	Macropus eugenii	81.41	0.00e+00	868.00
IUUC-Mor-056960	Magnaporthe oryzae	66.26	2.00e-137	482.00
IUUC-Mtr-057816	Medicago truncatula	47.36	3.00e-127	448.00
IUUC-Mla-059031	Melampsora laricipopulina	65.41	2.00e-127	448.00
IUUC-Mga-059337	Meleagris gallopavo	88.72	0.00e+00	954.00
IUUC-Mvi-060217	Microbotryum violaceum	64.78	4.00e-130	457.00
IUUC-Mmr-061018	Microcebus murinus	97.09	0.00e+00	1043.00
IUUC-Mdo-062863	Monodelphis domestica	90.31	0.00e+00	944.00
IUUC-Mmu-063988	Mus musculus	96.30	0.00e+00	1032.00
IUUC-Mac-064459	Musa acuminata	48.69	7.00e-123	433.00
IUUC-Mpu-066559	Mustela putorius furo	96.12	0.00e+00	1035.00
IUUC-Mlu-067361	Myotis lucifugus	93.15	0.00e+00	985.00
IUUC-Nfi-068492	Neosartorya fischeri	64.94	2.00e-129	455.00
IUUC-Ncr-068808	Neurospora crassa	65.14	7.00e-137	480.00
IUUC-Nle-069875	Nomascus leucogenys	100.00	0.00e+00	1073.00
IUUC-Opr-070462	Ochotona princeps	98.12	4.00e-158	551.00
IUUC-Ont-071365	Oreochromis niloticus	76.74	0.00e+00	831.00
IUUC-Oan-072708	Ornithorhynchus anatinus	90.47	0.00e+00	972.00
IUUC-Ocu-074594	Oryctolagus cuniculus	96.31	0.00e+00	1035.00
IUUC-Oba-075570	Oryza barthii	59.66	2.00e-127	448.00
IUUC-Obr-076366	Oryza brachyantha	64.83	2.00e-92	332.00
IUUC-Ogl-077153	Oryza glaberrima	59.33	8.00e-127	447.00
IUUC-Ogu-078540	Oryza glumaepatula	59.33	2.00e-127	449.00
IUUC-Oin-079612	Oryza indica	58.52	1.00e-125	442.00
IUUC-Olo-081077	Oryza longistaminata	58.52	1.00e-125	442.00
IUUC-Ome-081236	Oryza meridionalis	58.24	2.00e-125	442.00
IUUC-Oni-082499	Oryza nivara	59.33	2.00e-127	449.00
IUUC-Opu-083499	Oryza punctata	58.52	2.00e-125	442.00
IUUC-Oru-084276	Oryza rufipogon	59.33	2.00e-127	449.00
IUUC-Osa-085849	Oryza sativa	59.33	2.00e-127	449.00
IUUC-Ola-086655	Oryzias latipes	75.63	0.00e+00	818.00
IUUC-Olu-087637	Ostreococcus lucimarinus	58.06	4.00e-120	424.00
IUUC-Oga-087934	Otolemur garnettii	96.90	0.00e+00	1037.00
IUUC-Oar-090185	Ovis aries	94.57	0.00e+00	1011.00
IUUC-Pan-092622	Papio anubis	99.61	0.00e+00	1070.00
IUUC-Psi-093320	Pelodiscus sinensis	88.97	0.00e+00	956.00
IUUC-Pma-094638	Petromyzon marinus	76.89	0.00e+00	837.00
IUUC-Pno-094826	Phaeosphaeria nodorum	46.40	7.00e-106	377.00
IUUC-Ppa-095576	Physcomitrella patens	63.99	3.00e-124	438.00
IUUC-Pfo-096894	Poecilia formosa	77.80	0.00e+00	843.00
IUUC-Pab-098020	Pongo abelii	99.81	0.00e+00	1072.00
IUUC-Pop-099180	Populus trichocarpa	48.02	3.00e-127	448.00
IUUC-Pca-100909	Procavia capensis	90.27	0.00e+00	818.00
IUUC-Ppe-101346	Prunus persica	47.05	7.00e-127	447.00
IUUC-Pva-102167	Pteropus vampyrus	77.86	0.00e+00	790.00
IUUC-Pgr-103516	Puccinia graminis	49.90	5.00e-130	457.00
IUUC-Ptt-103738	Puccinia triticina	50.00	7.00e-131	460.00
IUUC-Pte-104352	Pyrenophora teres	52.61	5.00e-131	461.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	53.10	6.00e-132	464.00
IUUC-Rno-105291	Rattus norvegicus	96.50	0.00e+00	1041.00
IUUC-Sce-106204	Saccharomyces cerevisiae	50.15	8.00e-104	370.00
IUUC-Sha-106943	Sarcophilus harrisii	89.94	0.00e+00	936.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	65.08	8.00e-130	456.00
IUUC-Spo-108049	Schizosaccharomyces pombe	62.54	3.00e-135	474.00
IUUC-Smo-109043	Selaginella moellendorffii	60.48	2.00e-125	441.00
IUUC-Sit-110431	Setaria italica	51.16	3.00e-131	461.00
IUUC-Sly-111391	Solanum lycopersicum	48.95	2.00e-120	425.00
IUUC-Stu-112364	Solanum tuberosum	55.26	4.00e-96	343.00
IUUC-Sar-113450	Sorex araneus	98.85	0.00e+00	725.00
IUUC-Sbi-113829	Sorghum bicolor	50.00	1.00e-130	459.00
IUUC-Sre-115153	Sporisorium reilianum	61.16	8.00e-122	430.00
IUUC-Ssc-115798	Sus scrofa	95.16	0.00e+00	1021.00
IUUC-Tgu-117417	Taeniopygia guttata	90.06	0.00e+00	961.00
IUUC-Tru-117615	Takifugu rubripes	75.44	0.00e+00	783.00
IUUC-Tsy-119480	Tarsius syrichta	97.65	0.00e+00	1043.00
IUUC-Tni-119847	Tetraodon nigroviridis	75.14	0.00e+00	811.00
IUUC-Tca-121287	Theobroma cacao	47.95	1.00e-127	449.00
IUUC-Tre-122010	Trichoderma reesei	64.91	7.00e-143	500.00
IUUC-Tvi-122475	Trichoderma virens	61.19	6.00e-142	497.00
IUUC-Tae-124397	Triticum aestivum	50.31	2.00e-134	472.00
IUUC-Tur-126116	Triticum urartu	42.35	8.00e-101	360.00
IUUC-Tme-126992	Tuber melanosporum	65.24	2.00e-136	479.00
IUUC-Tbe-127803	Tupaia belangeri	85.98	0.00e+00	747.00
IUUC-Ttr-128933	Tursiops truncatus	95.73	0.00e+00	1026.00
IUUC-Uma-129447	Ustilago maydis	59.69	9.00e-118	417.00
IUUC-Vda-129780	Verticillium dahliae	54.61	2.00e-138	485.00
IUUC-Vpa-130557	Vicugna pacos	88.26	3.00e-118	418.00
IUUC-Vvi-130918	Vitis vinifera	47.19	1.00e-121	429.00
IUUC-Xtr-132409	Xenopus tropicalis	84.91	0.00e+00	882.00
IUUC-Xma-133420	Xiphophorus maculatus	77.91	0.00e+00	846.00
IUUC-Yli-134362	Yarrowia lipolytica	51.83	8.00e-122	430.00
IUUC-Zma-135804	Zea mays	58.84	2.00e-125	442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence