iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108330

Ensembl Protein ID

SPBC14C8.17c.1:pep

UniProt Accession

O60097; SPT8_SCHPO

Genbank Protein ID

CAA18434.1

Protein Name

Transcription factor spt8

Genbank Nucleotide ID

CU329671

Gene Name

spt8; sep9; SPBC14C8.17c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC14C8.17c	SPBC14C8.17c.1	SPBC14C8.17c.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-12	42.9	231	266

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           Ht++v+cla+  s++ ++sGs+D+ ++ WDl tg+ 
   Q: 231  HTAPVSCLALhgSEKKVLSGSWDKMVYYWDLNTGDA 266
           **********97779****************99986 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Functions as a component of the transcription regulatory histone acetylation (HAT) complex SAGA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery (By similarity).

Protein Sequence
(Fasta)

MEAEESESFS YPMLLPSDGL YPEDDDDADM DQDKNPEENV MNEKEDEDVD AVDEKSGEED 60
VEMDTMEDEN ENDEDTEQTS EKKETEETPK ENPLEKLKQK ASTASFYDVV PTLAIPMATS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTACGCTA AATATATTCA ACGGTCTTAA ACTTATAATT CCTTTTAATA TCTCAGAGGG 60
AACGTAAACA AAACATATTG TTGCTGCATT GCAGCATTTT AAGGTTACAA CTCTTTTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0000124--C:SAGA complex
GO:0017025--F:TBP-class protein binding
GO:0003712--F:transcription cofactor activity
GO:0016573--P:histone acetylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

KEGG

spo:SPBC14C8.17c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007730	Ashbya gossypii	38.84	3.00e-90	323.00
IUUC-Acl-008082	Aspergillus clavatus	53.12	3.00e-57	214.00
IUUC-Afl-008500	Aspergillus flavus	55.15	4.00e-54	204.00
IUUC-Afu-008923	Aspergillus fumigatus	54.55	4.00e-53	200.00
IUUC-Ani-009147	Aspergillus nidulans	52.33	9.00e-56	209.00
IUUC-Ang-009566	Aspergillus niger	46.50	3.00e-104	370.00
IUUC-Aor-010108	Aspergillus oryzae	55.15	5.00e-54	203.00
IUUC-Ate-010560	Aspergillus terreus	51.16	5.00e-51	193.00
IUUC-Bgr-012309	Blumeria graminis	49.78	2.00e-55	208.00
IUUC-Bci-013614	Botrytis cinerea	43.72	4.00e-54	204.00
IUUC-Cgl-026527	Colletotrichum gloeosporioides	52.58	1.00e-54	206.00
IUUC-Cne-027016	Cryptococcus neoformans	33.61	2.00e-36	145.00
IUUC-Dse-031194	Dothistroma septosporum	47.96	5.00e-49	187.00
IUUC-Fox-037991	Fusarium oxysporum	47.01	3.00e-54	204.00
IUUC-Fso-038399	Fusarium solani	48.47	4.00e-55	207.00
IUUC-Ggr-039756	Gaeumannomyces graminis	49.09	7.00e-53	200.00
IUUC-Kpa-049379	Komagataella pastoris	35.87	6.00e-81	292.00
IUUC-Lma-053094	Leptosphaeria maculans	52.88	6.00e-56	210.00
IUUC-Mor-056920	Magnaporthe oryzae	42.75	4.00e-50	191.00
IUUC-Mla-058891	Melampsora laricipopulina	28.12	7.00e-44	170.00
IUUC-Mvi-060352	Microbotryum violaceum	39.52	1.00e-33	135.00
IUUC-Nfi-068276	Neosartorya fischeri	55.91	1.00e-50	192.00
IUUC-Ncr-068871	Neurospora crassa	46.84	6.00e-52	196.00
IUUC-Pno-094917	Phaeosphaeria nodorum	53.40	9.00e-57	213.00
IUUC-Pgr-103632	Puccinia graminis	38.10	2.00e-24	105.00
IUUC-Ptt-103790	Puccinia triticina	31.16	1.00e-23	103.00
IUUC-Pte-104169	Pyrenophora teres	53.93	4.00e-57	213.00
IUUC-Pyt-104624	Pyrenophora triticirepentis	53.93	5.00e-57	213.00
IUUC-Sce-106280	Saccharomyces cerevisiae	36.40	9.00e-89	318.00
IUUC-Sja-107893	Schizosaccharomyces japonicus	60.37	1.00e-154	537.00
IUUC-Sre-114899	Sporisorium reilianum	37.93	4.00e-35	141.00
IUUC-Tre-122019	Trichoderma reesei	55.88	1.00e-58	219.00
IUUC-Tvi-122319	Trichoderma virens	45.39	2.00e-57	214.00
IUUC-Tme-126879	Tuber melanosporum	43.01	5.00e-93	333.00
IUUC-Uma-129635	Ustilago maydis	38.24	9.00e-37	147.00
IUUC-Vda-129679	Verticillium dahliae	51.17	4.00e-54	204.00
IUUC-Yli-134619	Yarrowia lipolytica	43.70	5.00e-101	359.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence