iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006859

UUCD1 version

UUC-ArT-00464

Ensembl Protein ID

AT2G31510.1

UniProt Accession

Q84RR0; Q9SIQ6; ARI7_ARATH

Genbank Protein ID

CAD52889.1; AAD24830.1; AEC08556.1; AT2G31510.1

Protein Name

Probable E3 ubiquitin-protein ligase ARI7; ARIADNE-like protein ARI7; Protein ariadne homolog 7; RING-type E3 ubiquitin transferase ARI7

Genbank Nucleotide ID

AJ510210; AC007071; CP002685; BX820609

Gene Name

ARI7; At2g31510; T9H9.3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G31510	AT2G31510.2	AT2G31510.2
AT2G31510	AT2G31510.1	AT2G31510.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein Expression/Proteomics
GPMDB

Status

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	7.50e-47	160.4	137	325

Active Site

Position(s)	Description	Evidence
308	N/A	{ECO:0000250\|UniProtKB:Q9Y4X5}

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqv.teiscpaaecpekleeseikellveeelykryekllleevveadaalk 89
           C +C+ ++++e++  +++C h fC+ C++ y++++i++g     + cp+++c + + ++ + + l++e+ +++y+++ l++++e ++++k
   Q: 137  CGICFDSYPPEKIA-SVSCGHPFCTTCWTGYISTTINDGPGcLMLRCPDPSCLAAVGHDMVDK-LASEDEKEKYNRYFLRSYIEDNRKMK 224
           99********8776.77**********************8758899*****************.699999******************** PP
   S: 90   wcpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnh 179
           wcpap+C++++ +   + +  v+c  c++ fC++C ee+H++++C++++++  k++    e+e+++++ ansk+Cp+Ck +iekn+gC+h
   Q: 225  WCPAPGCDFAIDFVAGSGNYDVSC-LCSFSFCWNCTEEAHRPVDCSTVSKWILKNS---AESENMNWILANSKPCPRCKRPIEKNQGCMH 310
           ***********9999999******.9***************************999...89***************************** PP
   S: 180  mtC.akCkaefCwlC 193
           mtC   Ck+efCwlC
   Q: 311  MTCtPPCKYEFCWLC 325
           ***778********* PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.

Protein Sequence
(Fasta)

MDSEEDMLDA HDMESGEDDF YSGGTDDCND SDDGEPDYGF VEEDADDSAM IASHRSQKNF 60
CVLREEDIRR HQMDNIERVS VVLSITEVEA SILLRHFHWS VGRVHDEWFA DEERVRKTVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAAGTAAA GGAAAAAAGA AAAACAATAA TCTTCCTCCA AAATCATAAT CATTTCCATT 60
TGTTGAGAGG CATGTTAGAT TTTTTGGTAC TAACTTTATG AAAATGATAA ATGTGATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT2G31510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003749	Anas platyrhynchos	27.60	3.00e-59	223.00
IUUC-Aca-004337	Anolis carolinensis	27.79	1.00e-59	224.00
IUUC-Aly-005665	Arabidopsis lyrata	97.86	0.00e+00	1039.00
IUUC-Acl-008252	Aspergillus clavatus	33.10	1.00e-66	246.00
IUUC-Afu-009062	Aspergillus fumigatus	32.86	5.00e-67	248.00
IUUC-Ani-009219	Aspergillus nidulans	33.97	3.00e-66	245.00
IUUC-Ang-009538	Aspergillus niger	33.64	7.00e-64	237.00
IUUC-Ate-010497	Aspergillus terreus	33.64	9.00e-64	237.00
IUUC-Bgr-012016	Blumeria graminis	30.71	4.00e-65	241.00
IUUC-Bci-013819	Botrytis cinerea	32.37	6.00e-70	257.00
IUUC-Bol-016087	Brassica oleracea	92.22	0.00e+00	1007.00
IUUC-Bra-017944	Brassica rapa	91.67	0.00e+00	959.00
IUUC-Cja-019418	Callithrix jacchus	27.98	1.00e-58	221.00
IUUC-Csa-023239	Chlorocebus sabaeus	27.98	9.00e-59	221.00
IUUC-Cgl-026434	Colletotrichum gloeosporioides	31.13	2.00e-69	255.00
IUUC-Dse-031171	Dothistroma septosporum	32.90	1.00e-68	253.00
IUUC-Ete-032355	Echinops telfairi	30.87	6.00e-46	177.00
IUUC-Fca-036063	Felis catus	28.17	2.00e-58	220.00
IUUC-Fso-038125	Fusarium solani	33.10	2.00e-69	255.00
IUUC-Ggr-039722	Gaeumannomyces graminis	32.24	1.00e-65	243.00
IUUC-Gga-040616	Gallus gallus	27.79	7.00e-59	222.00
IUUC-Gma-042954	Glycine max	76.05	0.00e+00	836.00
IUUC-Itr-048370	Ictidomys tridecemlineatus	30.39	3.00e-50	191.00
IUUC-Lma-053253	Leptosphaeria maculans	33.63	2.00e-73	269.00
IUUC-Laf-053411	Loxodonta africana	27.60	1.00e-57	218.00
IUUC-Mcc-055098	Macaca mulatta	27.98	8.00e-59	221.00
IUUC-Meu-056332	Macropus eugenii	29.48	5.00e-48	184.00
IUUC-Mor-057179	Magnaporthe oryzae	31.28	7.00e-67	247.00
IUUC-Mpo-057553	Magnaporthe poae	31.81	4.00e-65	241.00
IUUC-Mtr-058263	Medicago truncatula	71.86	0.00e+00	798.00
IUUC-Mga-059352	Meleagris gallopavo	27.82	1.00e-58	221.00
IUUC-Mvi-060517	Microbotryum violaceum	33.64	1.00e-68	253.00
IUUC-Mmr-061763	Microcebus murinus	27.79	4.00e-58	219.00
IUUC-Nfi-068339	Neosartorya fischeri	33.10	1.00e-67	250.00
IUUC-Ncr-068947	Neurospora crassa	31.81	6.00e-63	234.00
IUUC-Opr-070518	Ochotona princeps	29.78	4.00e-49	188.00
IUUC-Ont-072092	Oreochromis niloticus	30.15	6.00e-60	225.00
IUUC-Ocu-074462	Oryctolagus cuniculus	27.60	2.00e-57	217.00
IUUC-Ola-086873	Oryzias latipes	30.04	7.00e-61	228.00
IUUC-Olu-087826	Ostreococcus lucimarinus	34.65	1.00e-78	286.00
IUUC-Pan-092334	Papio anubis	27.98	6.00e-60	225.00
IUUC-Psi-093827	Pelodiscus sinensis	27.46	4.00e-58	219.00
IUUC-Pma-094243	Petromyzon marinus	26.94	3.00e-51	196.00
IUUC-Pno-095124	Phaeosphaeria nodorum	27.79	1.00e-47	183.00
IUUC-Pfo-097370	Poecilia formosa	30.50	8.00e-62	231.00
IUUC-Pca-100700	Procavia capensis	28.09	2.00e-41	162.00
IUUC-Pgr-103443	Puccinia graminis	29.98	2.00e-58	219.00
IUUC-Pte-104022	Pyrenophora teres	32.58	6.00e-66	244.00
IUUC-Pyt-104643	Pyrenophora triticirepentis	34.00	8.00e-73	267.00
IUUC-Sce-106154	Saccharomyces cerevisiae	27.15	2.00e-46	179.00
IUUC-Sha-107341	Sarcophilus harrisii	28.34	3.00e-59	223.00
IUUC-Sja-107977	Schizosaccharomyces japonicus	30.69	3.00e-62	231.00
IUUC-Spo-108222	Schizosaccharomyces pombe	31.43	6.00e-66	244.00
IUUC-Stu-112533	Solanum tuberosum	72.54	0.00e+00	797.00
IUUC-Sar-113328	Sorex araneus	28.93	2.00e-56	214.00
IUUC-Sre-115120	Sporisorium reilianum	31.45	1.00e-60	226.00
IUUC-Ssc-115681	Sus scrofa	28.01	6.00e-60	225.00
IUUC-Tgu-116830	Taeniopygia guttata	27.79	2.00e-58	220.00
IUUC-Tru-117711	Takifugu rubripes	30.79	5.00e-63	235.00
IUUC-Tre-121902	Trichoderma reesei	32.65	1.00e-70	259.00
IUUC-Tvi-122474	Trichoderma virens	32.87	2.00e-70	259.00
IUUC-Tbe-127647	Tupaia belangeri	29.46	1.00e-41	164.00
IUUC-Ttr-129218	Tursiops truncatus	27.79	4.00e-56	213.00
IUUC-Uma-129487	Ustilago maydis	31.16	9.00e-62	230.00
IUUC-Vda-129939	Verticillium dahliae	32.06	1.00e-66	246.00
IUUC-Vpa-130603	Vicugna pacos	27.60	3.00e-57	216.00
IUUC-Xma-133029	Xiphophorus maculatus	30.50	5.00e-62	232.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence