iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129880

Ensembl Protein ID

EGY14320

UniProt Accession

G2X5H9; G2X5H9_VERDV

Genbank Protein ID

EGY14320.1

Protein Name

Ubiquitin-protein ligase E3A

Genbank Nucleotide ID

DS572704

Gene Name

VDAG_05484

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_05484	EGY14320	EGY14320

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.00e-61	206.0	969	1305

Active Site

Position(s)	Description	Evidence
1274	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 15   gEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsl.edlee 112
           gEeg d gGv++ef+ l ++e  +pd g+f+ +e+ +  +++ p s++        Fe+lG+l+ +a+++g  l+++++k++y++llg++++  +++++
   Q: 969  GEEGFDSGGVQQEFFRLAIAECLDPDFGAFTVDERTRMAWFV-PGSIV----PVWKFELLGILVSLAVYNGLTLPITFPKAMYRKLLGEPVDElHHIAD 1062
           69****************************999998888875.66775....4789***********************************866***** PP
   S: 113  vdpelykslkeikenaes..............dieelgldltfsvseei..............lgetkeeeLkpgGeni.pVtneNkeeYvklvveyrl 182
             p+l+  l+ ++e +e+              +   + +d                       l+  +e    ++ ++   Vt eN+++Yv++++ y  
   Q: 1063 GWPDLASGLTTLLEWDEKdgavedvfartyefS--VSMFDQ-------PisremnsenpnwpqLKAKSESLAAQNPADApLVTDENRNAYVSDYIRYLT 1152
           *************99855566665555444332..222222.......123333445577664444444433444444416****************** PP
   S: 183  kegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfae 281
             +++ q+eaf +Gf+  + +++l l+t+  l+ ++ G ++id+ +l++ t+y  g+ ++++a++ Fw+++++ +++ ++++L+FvT s+r+P+gG+++
   Q: 1153 DVSVRPQFEAFLRGFRACLHPKSLGLLTPPLLQSVVEGVQDIDIAELRRYTRY-VGWDASHRAVHDFWSIVKRYDDTMKRRLLEFVTASDRVPVGGMRN 1250
           *****************************************************.67******************************************* PP
   S: 282  lkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           l+   fv++k    +++  +lP++ TC+ +L LPeY+sk++l+++L +A e++kgF++
   Q: 1251 LQ---FVVQKngeeEGEGGHLPTAYTCYGTLLLPEYESKDVLRQRLAMALENSKGFGF 1305
           **...*****99966666**************************************96 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MTRLDRAPQE DGDDIFASLW EEAPPFARLP ADAPAELRQL VADIENPRRV YAVYRASRRH 60
NFQLLVERYV AQLRYGCDSE TCVTATCFTC RRRIAGKAPL RRYNTTSART LAVCLASQDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGCGAC TCGACCGTGC ACCACAAGAA GATGGCGACG ACATCTTTGC CTCGTTGTGG 60
GAGGAGGCGC CGCCCTTTGC GCGCCTGCCT GCTGATGCGC CAGCCGAGCT GAGGCAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

vda:VDAG_05484

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008265	Aspergillus clavatus	36.61	2.00e-80	293.00
IUUC-Afl-008437	Aspergillus flavus	39.36	1.00e-140	493.00
IUUC-Afu-008852	Aspergillus fumigatus	45.00	3.00e-140	491.00
IUUC-Ani-009330	Aspergillus nidulans	46.57	9.00e-84	303.00
IUUC-Ang-009616	Aspergillus niger	45.97	7.00e-142	496.00
IUUC-Aor-010162	Aspergillus oryzae	39.36	3.00e-141	494.00
IUUC-Ate-010475	Aspergillus terreus	37.55	4.00e-129	454.00
IUUC-Bgr-012015	Blumeria graminis	43.74	0.00e+00	1005.00
IUUC-Bci-013608	Botrytis cinerea	43.14	0.00e+00	995.00
IUUC-Cgl-026488	Colletotrichum gloeosporioides	63.94	0.00e+00	1504.00
IUUC-Dse-031435	Dothistroma septosporum	30.77	1.00e-66	246.00
IUUC-Fox-037915	Fusarium oxysporum	61.31	0.00e+00	945.00
IUUC-Fso-038357	Fusarium solani	52.86	0.00e+00	995.00
IUUC-Ggr-039765	Gaeumannomyces graminis	56.97	0.00e+00	1011.00
IUUC-Lma-053245	Leptosphaeria maculans	33.25	3.00e-102	365.00
IUUC-Mor-057108	Magnaporthe oryzae	52.79	0.00e+00	937.00
IUUC-Nfi-068554	Neosartorya fischeri	45.52	4.00e-141	494.00
IUUC-Ncr-068759	Neurospora crassa	50.69	0.00e+00	1077.00
IUUC-Pno-094886	Phaeosphaeria nodorum	36.06	3.00e-125	441.00
IUUC-Pte-104055	Pyrenophora teres	41.09	3.00e-106	378.00
IUUC-Pyt-104647	Pyrenophora triticirepentis	34.64	2.00e-115	409.00
IUUC-Ssl-108420	Sclerotinia sclerotiorum	42.32	0.00e+00	924.00
IUUC-Tre-121985	Trichoderma reesei	52.49	0.00e+00	1220.00
IUUC-Tvi-122335	Trichoderma virens	52.69	0.00e+00	1207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence