iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033675

Ensembl Protein ID

ENSECAP00000012336.1

UniProt Accession

F7CYQ4; F7CYQ4_HORSE

Protein Name

Uncharacterized protein

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014404.1	ENSECAT00000015354.1	ENSECAP00000012336.1
ENSECAG00000014404.1	ENSECAT00000015434.1	ENSECAP00000012403.1
ENSECAG00000014404.1	ENSECAT00000015481.1	ENSECAP00000012446.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-26	90.8	153	192
UBD/Beta-Prp	2.60e-52	178.0	495	751

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvll 36
           gH+ +v c+af ++ +++vs +  +D ++ vWD+++g l+
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKGILV 192
           89**********888*****9989*********9998765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgti.kvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkgheds 96
           ++++++spd+++la+g r+g + +++ +++   l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s
   Q: 495  VRVMQVSPDGQHLASGDRSGNLrQLHFMDE---LVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSS 580
           67899*****************67777777...789*************99887899**************9997888999******** PP
   S: 97   vlslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrt 174
           +++++f  ++   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ + 
   Q: 581  ITAIKFAGTRdIQMISCGADKSIYF---RSAQQASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKG 666
           ********775789*******9976...333333334445332122222333446777788****************988888888888 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrs 253
            +g +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ v+s++f+ +  +l+++s D  ++iW       ++ +
   Q: 667  SQG-DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTSMKFTYDCRHLITVSGDSCVFIWhlgpeltNCMK 751
           888.999999999**************************************************************66554444433 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAAIGPGGFA RNDAVEKLPS VMAGVSARRS QSSPPPAPPV CLRRRTRPLA APEDTMQNRV 60
SLEKVLGITA QNSNGLTCDP GTGHVAYLAG CVVVILNPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTGTGGCG GCGGCGGCGG TTGCGGAGTG TAACGGTCGC CCGGCTCCGG CGCGACGATG 60
GCGGCCATAG GGCCCGGAGG CTTCGCGCGG AACGATGCAG TCGAGAAGCT GCCATCCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005813--C:centrosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	84.04	0.00e+00	2447.00
IUUC-Aca-004935	Anolis carolinensis	70.70	0.00e+00	998.00
IUUC-Acl-008257	Aspergillus clavatus	22.14	2.00e-23	105.00
IUUC-Afu-008757	Aspergillus fumigatus	22.16	3.00e-28	120.00
IUUC-Bta-013336	Bos taurus	80.41	0.00e+00	2274.00
IUUC-Cel-018592	Caenorhabditis elegans	28.72	2.00e-74	275.00
IUUC-Cja-019094	Callithrix jacchus	78.78	0.00e+00	2237.00
IUUC-Cfa-020529	Canis familiaris	83.67	0.00e+00	2452.00
IUUC-Cpo-021970	Cavia porcellus	86.36	0.00e+00	1650.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	29.05	3.00e-14	73.60
IUUC-Csa-024161	Chlorocebus sabaeus	79.60	0.00e+00	2209.00
IUUC-Cho-024310	Choloepus hoffmanni	85.26	0.00e+00	1164.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.74	7.00e-23	102.00
IUUC-Dno-029933	Dasypus novemcinctus	77.47	0.00e+00	2166.00
IUUC-Dor-031147	Dipodomys ordii	76.74	0.00e+00	2121.00
IUUC-Dse-031501	Dothistroma septosporum	31.30	4.00e-22	100.00
IUUC-Eeu-034798	Erinaceus europaeus	89.19	0.00e+00	910.00
IUUC-Fca-035826	Felis catus	84.23	0.00e+00	2479.00
IUUC-Gma-043644	Glycine max	31.98	1.00e-101	364.00
IUUC-Ggo-045152	Gorilla gorilla	80.95	0.00e+00	2229.00
IUUC-Hsa-045891	Homo sapiens	81.08	0.00e+00	2232.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	92.53	0.00e+00	1547.00
IUUC-Lch-049669	Latimeria chalumnae	57.19	0.00e+00	985.00
IUUC-Loc-052488	Lepisosteus oculatus	59.40	0.00e+00	1016.00
IUUC-Laf-053992	Loxodonta africana	79.49	0.00e+00	2241.00
IUUC-Mcc-054994	Macaca mulatta	81.21	0.00e+00	2233.00
IUUC-Meu-056815	Macropus eugenii	80.67	0.00e+00	1405.00
IUUC-Mtr-058383	Medicago truncatula	30.70	4.00e-52	199.00
IUUC-Mmr-060693	Microcebus murinus	78.41	0.00e+00	2200.00
IUUC-Mdo-063007	Monodelphis domestica	63.31	0.00e+00	1762.00
IUUC-Mmu-064067	Mus musculus	75.16	0.00e+00	2122.00
IUUC-Mpu-066532	Mustela putorius furo	84.24	0.00e+00	2500.00
IUUC-Mlu-066982	Myotis lucifugus	82.00	0.00e+00	2245.00
IUUC-Nle-070042	Nomascus leucogenys	83.02	0.00e+00	1895.00
IUUC-Opr-070397	Ochotona princeps	77.32	0.00e+00	2208.00
IUUC-Oan-073119	Ornithorhynchus anatinus	66.23	0.00e+00	861.00
IUUC-Ocu-074274	Oryctolagus cuniculus	79.46	0.00e+00	2192.00
IUUC-Oga-088577	Otolemur garnettii	80.94	0.00e+00	2302.00
IUUC-Oar-090117	Ovis aries	80.46	0.00e+00	2246.00
IUUC-Ptr-090553	Pan troglodytes	81.15	0.00e+00	2251.00
IUUC-Pan-092559	Papio anubis	71.88	0.00e+00	1060.00
IUUC-Psi-093710	Pelodiscus sinensis	64.49	0.00e+00	1370.00
IUUC-Pab-098510	Pongo abelii	80.36	0.00e+00	2179.00
IUUC-Pop-099155	Populus trichocarpa	31.38	2.00e-97	350.00
IUUC-Pca-100323	Procavia capensis	70.34	0.00e+00	1311.00
IUUC-Pva-102895	Pteropus vampyrus	82.86	0.00e+00	2364.00
IUUC-Rno-105598	Rattus norvegicus	75.73	0.00e+00	2167.00
IUUC-Sha-107013	Sarcophilus harrisii	66.34	0.00e+00	1787.00
IUUC-Smo-109134	Selaginella moellendorffii	37.73	1.00e-134	474.00
IUUC-Sar-113261	Sorex araneus	75.32	0.00e+00	2146.00
IUUC-Ssc-115317	Sus scrofa	83.33	0.00e+00	2334.00
IUUC-Tsy-118799	Tarsius syrichta	91.25	0.00e+00	861.00
IUUC-Tme-127128	Tuber melanosporum	24.03	1.00e-31	132.00
IUUC-Tbe-127555	Tupaia belangeri	93.05	0.00e+00	1012.00
IUUC-Ttr-128722	Tursiops truncatus	82.19	0.00e+00	2320.00
IUUC-Vda-129957	Verticillium dahliae	23.55	1.00e-28	122.00
IUUC-Vpa-130392	Vicugna pacos	61.92	5.00e-172	598.00
IUUC-Vvi-131035	Vitis vinifera	33.52	9.00e-105	374.00
IUUC-Xtr-131789	Xenopus tropicalis	59.05	0.00e+00	978.00
IUUC-Yli-134437	Yarrowia lipolytica	29.82	1.00e-16	82.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence