iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073305

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01147960

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000007444.3	ENSOANT00000011856.3	ENSOANP00000011854.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.00e-08	33.1	12	53
UBD/SH3	4.70e-48	161.2	447	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
             ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 447  YVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 501
           679**********************9.555.569********************988 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGCGV 60
DELPSNILLV RLLDGIKQRP RKSGTGGGGG TNCTSALRVQ SGPVANCSAK EPQISQGGPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATCACCGA ATGCTCCATT TAAATCCGTT TATGAACGCC CCCGAGGAAG GAAGAGTAAA 60
CTAAATGTCA GAGTGCTTGG CTCCTGACCT CTACCACCCT TACGGATGTC TCGATATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

oaa:100077176

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	79.80	0.00e+00	1160.00
IUUC-Apl-003961	Anas platyrhynchos	82.82	0.00e+00	1211.00
IUUC-Aca-004386	Anolis carolinensis	77.84	0.00e+00	1194.00
IUUC-Ago-007765	Ashbya gossypii	35.16	7.00e-12	64.30
IUUC-Ame-010659	Astyanax mexicanus	60.66	0.00e+00	880.00
IUUC-Bta-012563	Bos taurus	87.18	6.00e-106	377.00
IUUC-Cja-019730	Callithrix jacchus	80.13	0.00e+00	1185.00
IUUC-Cfa-020992	Canis familiaris	80.32	0.00e+00	1208.00
IUUC-Cpo-021304	Cavia porcellus	81.46	0.00e+00	1250.00
IUUC-Csa-023925	Chlorocebus sabaeus	79.08	0.00e+00	1173.00
IUUC-Cho-024630	Choloepus hoffmanni	78.55	1.00e-163	569.00
IUUC-Cin-025274	Ciona intestinalis	46.30	1.00e-72	265.00
IUUC-Csv-026136	Ciona savignyi	42.78	1.00e-73	269.00
IUUC-Cme-027278	Cyanidioschyzon merolae	44.19	2.00e-07	50.40
IUUC-Dre-028290	Danio rerio	63.65	0.00e+00	918.00
IUUC-Dno-029083	Dasypus novemcinctus	80.61	0.00e+00	1144.00
IUUC-Dor-030388	Dipodomys ordii	88.20	6.00e-176	610.00
IUUC-Dme-032207	Drosophila melanogaster	47.76	2.00e-67	249.00
IUUC-Ete-032809	Echinops telfairi	70.10	0.00e+00	731.00
IUUC-Eca-034185	Equus caballus	79.97	0.00e+00	986.00
IUUC-Eeu-034816	Erinaceus europaeus	69.24	0.00e+00	979.00
IUUC-Fca-036439	Felis catus	78.86	0.00e+00	1208.00
IUUC-Fal-037074	Ficedula albicollis	82.37	0.00e+00	1206.00
IUUC-Gmo-039443	Gadus morhua	68.20	1.00e-92	333.00
IUUC-Ggr-040119	Gaeumannomyces graminis	40.68	6.00e-12	66.20
IUUC-Gga-040749	Gallus gallus	84.72	0.00e+00	964.00
IUUC-Gac-041420	Gasterosteus aculeatus	75.48	5.00e-149	521.00
IUUC-Ggo-045215	Gorilla gorilla	80.74	0.00e+00	1206.00
IUUC-Hsa-046315	Homo sapiens	80.65	0.00e+00	1198.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	73.63	1.00e-124	438.00
IUUC-Lch-049453	Latimeria chalumnae	73.21	0.00e+00	900.00
IUUC-Loc-052248	Lepisosteus oculatus	39.07	3.00e-76	279.00
IUUC-Laf-053651	Loxodonta africana	80.74	0.00e+00	1170.00
IUUC-Mcc-054688	Macaca mulatta	79.12	0.00e+00	1195.00
IUUC-Meu-056291	Macropus eugenii	74.93	0.00e+00	769.00
IUUC-Mor-056932	Magnaporthe oryzae	39.34	4.00e-12	67.00
IUUC-Mpo-057322	Magnaporthe poae	41.38	6.00e-12	66.20
IUUC-Mga-059944	Meleagris gallopavo	80.68	0.00e+00	1176.00
IUUC-Mmr-061553	Microcebus murinus	78.35	0.00e+00	1138.00
IUUC-Mdo-062313	Monodelphis domestica	76.92	0.00e+00	1159.00
IUUC-Mmu-063516	Mus musculus	80.49	0.00e+00	1249.00
IUUC-Mpu-066064	Mustela putorius furo	80.61	0.00e+00	1186.00
IUUC-Mlu-067312	Myotis lucifugus	78.79	0.00e+00	1154.00
IUUC-Nle-069035	Nomascus leucogenys	81.08	0.00e+00	1207.00
IUUC-Opr-070690	Ochotona princeps	75.05	5.00e-161	560.00
IUUC-Ont-071484	Oreochromis niloticus	67.68	0.00e+00	725.00
IUUC-Ocu-074936	Oryctolagus cuniculus	83.60	0.00e+00	959.00
IUUC-Ola-086675	Oryzias latipes	61.51	2.00e-180	625.00
IUUC-Oga-087933	Otolemur garnettii	74.47	0.00e+00	934.00
IUUC-Oar-090408	Ovis aries	86.44	2.00e-106	379.00
IUUC-Ptr-090865	Pan troglodytes	80.88	0.00e+00	1204.00
IUUC-Pan-092362	Papio anubis	79.30	0.00e+00	1174.00
IUUC-Psi-093876	Pelodiscus sinensis	81.16	0.00e+00	1204.00
IUUC-Pfo-097116	Poecilia formosa	61.02	0.00e+00	872.00
IUUC-Pab-098127	Pongo abelii	80.88	0.00e+00	1204.00
IUUC-Pca-100485	Procavia capensis	81.40	0.00e+00	909.00
IUUC-Pva-102661	Pteropus vampyrus	77.43	0.00e+00	1132.00
IUUC-Rno-105728	Rattus norvegicus	79.44	0.00e+00	1205.00
IUUC-Sha-106515	Sarcophilus harrisii	84.75	0.00e+00	860.00
IUUC-Sar-113161	Sorex araneus	89.33	6.00e-176	610.00
IUUC-Ssc-115314	Sus scrofa	72.89	0.00e+00	1006.00
IUUC-Tgu-117012	Taeniopygia guttata	82.82	0.00e+00	1195.00
IUUC-Tru-118467	Takifugu rubripes	62.22	2.00e-162	565.00
IUUC-Tsy-119566	Tarsius syrichta	80.19	2.00e-165	575.00
IUUC-Tni-120830	Tetraodon nigroviridis	65.42	3.00e-119	422.00
IUUC-Tbe-128070	Tupaia belangeri	90.84	0.00e+00	655.00
IUUC-Ttr-128161	Tursiops truncatus	89.80	7.00e-130	457.00
IUUC-Vda-129797	Verticillium dahliae	36.14	3.00e-09	57.00
IUUC-Xtr-132628	Xenopus tropicalis	76.26	0.00e+00	884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence