iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108051

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2 14; E2 ubiquitin-conjugating enzyme 14; Ubiquitin carrier protein 14; Ubiquitin-protein ligase 14

Genbank Nucleotide ID

CU329670

Gene Name

ubc14; SPAC1250.03

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC1250.03	SPAC1250.03.1	SPAC1250.03.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.70e-45	150.3	11	146

Active Site

Position(s)	Description	Evidence
91	Glycyl thioester intermediate	{ECO:0000250\|UniProtKB:P15731, ECO:0000255\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           Rl+ke+++l+++p + i++++vd+ +l++w ++ lGp+d++Y+gg+F+++++fp dYPf+PP+++f+t+i+hPn++++G+vCl ilk ++  
   Q: 11   RLTKEYSDLREHPIPDIRVNLVDD-NLFHWACTALGPSDSVYAGGKFHFSLKFPLDYPFQPPTIEFTTRIYHPNFDSEGNVCLAILK-QQVF 100
           99**********************.9************************************************************6.9*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +p ++++svl +i +ll+epnp++pl +++ae+++++r +++k++r
   Q: 101  KPSIKLRSVLEQILQLLREPNPDDPLVASIAEQYRNDRPSFDKIAR 146
           ******************************************9987 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.

Protein Sequence
(Fasta)

MASASPSSSR RLTKEYSDLR EHPIPDIRVN LVDDNLFHWA CTALGPSDSV YAGGKFHFSL 60
KFPLDYPFQP PTIEFTTRIY HPNFDSEGNV CLAILKQQVF KPSIKLRSVL EQILQLLREP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCTG CATCACCTTC ATCTTCCAGA AGACTGACAA AAGTAAGTAA ATTTTTATAT 60
TTTTACTTTA TTCTTACATA GCTAATATTC AAATGGTAAC CAGGAATATT CTGACTTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity

KEGG

spo:SPAC1250.03

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ggr-039991	Gaeumannomyces graminis	46.26	2.00e-35	139.00
IUUC-Mor-056993	Magnaporthe oryzae	49.66	5.00e-40	154.00
IUUC-Mpo-057350	Magnaporthe poae	44.90	3.00e-35	138.00
IUUC-Mla-058973	Melampsora laricipopulina	46.48	7.00e-40	154.00
IUUC-Mvi-060255	Microbotryum violaceum	46.48	3.00e-38	149.00
IUUC-Ncr-068814	Neurospora crassa	51.70	5.00e-39	151.00
IUUC-Pgr-103630	Puccinia graminis	46.48	1.00e-37	146.00
IUUC-Ptt-103816	Puccinia triticina	45.77	1.00e-36	143.00
IUUC-Sja-107884	Schizosaccharomyces japonicus	58.74	8.00e-41	157.00
IUUC-Tme-127163	Tuber melanosporum	45.52	4.00e-39	151.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence