iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004063

Ensembl Protein ID

ENSAPLP00000014685.1

UniProt Accession

U3J5A8; U3J5A8_ANAPL

Genbank Protein ID

ENSAPLP00000014685

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01015461

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014846.1	ENSAPLT00000015468.1	ENSAPLP00000014685.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.90e-47	160.2	2	139

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 9    lekdppegisakpvdesdltewevlilGpedtpYegg...........vFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsil 86
           l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g           +Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il
   Q: 2    LQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGkqivfmfvwtgTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDIL 89
           89************99.9*****************86333333333227**************************************** PP
   S: 87   keeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +  ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 90   Q--NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 139
           9..**********************************************996 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

RLQEDPPVGV SGAPSENNIM QWNAVIFGPE GTPFEDGKQI VFMFVWTGTF KLVIEFSEEY 60
PNKPPTVRFL SKMFHPNVYA DGSICLDILQ NRWSPTYDVS SILTSIQSLL DEPNPNSPAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTTGCAAG AAGACCCTCC TGTGGGTGTC AGTGGTGCAC CGTCTGAGAA TAATATAATG 60
CAGTGGAATG CAGTTATATT TGGGTAAGAG CTTTTGGTCG CTACCAAGTC CTACATCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	69.18	4.00e-58	216.00
IUUC-Aml-002120	Ailuropoda melanoleuca	92.62	2.00e-76	277.00
IUUC-Atr-002862	Amborella trichopoda	70.75	9.00e-60	221.00
IUUC-Aca-005001	Anolis carolinensis	91.95	2.00e-76	276.00
IUUC-Aly-005584	Arabidopsis lyrata	70.55	5.00e-59	219.00
IUUC-Ath-007149	Arabidopsis thaliana	70.55	5.00e-59	219.00
IUUC-Ago-007745	Ashbya gossypii	61.64	2.00e-51	194.00
IUUC-Acl-008139	Aspergillus clavatus	61.49	2.00e-53	200.00
IUUC-Afl-008551	Aspergillus flavus	61.49	3.00e-53	199.00
IUUC-Afu-008980	Aspergillus fumigatus	61.49	3.00e-53	199.00
IUUC-Ang-009554	Aspergillus niger	61.49	3.00e-53	199.00
IUUC-Aor-010242	Aspergillus oryzae	61.49	3.00e-53	199.00
IUUC-Ate-010390	Aspergillus terreus	61.49	3.00e-53	199.00
IUUC-Ame-011900	Astyanax mexicanus	87.92	1.00e-73	267.00
IUUC-Bgr-012039	Blumeria graminis	61.90	3.00e-53	199.00
IUUC-Bta-012840	Bos taurus	92.62	2.00e-76	277.00
IUUC-Bci-013919	Botrytis cinerea	61.74	3.00e-54	202.00
IUUC-Bdi-014475	Brachypodium distachyon	69.86	9.00e-59	218.00
IUUC-Bol-015726	Brassica oleracea	70.55	2.00e-58	219.00
IUUC-Bra-016643	Brassica rapa	70.55	5.00e-59	219.00
IUUC-Cel-018244	Caenorhabditis elegans	78.08	1.00e-65	241.00
IUUC-Cja-019737	Callithrix jacchus	92.62	2.00e-76	277.00
IUUC-Cfa-020244	Canis familiaris	92.62	2.00e-76	277.00
IUUC-Cpo-022192	Cavia porcellus	92.62	2.00e-76	277.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	69.84	4.00e-47	179.00
IUUC-Csa-023430	Chlorocebus sabaeus	92.62	2.00e-76	277.00
IUUC-Cho-025061	Choloepus hoffmanni	85.00	5.00e-55	205.00
IUUC-Cin-025537	Ciona intestinalis	73.15	5.00e-50	189.00
IUUC-Csv-025846	Ciona savignyi	74.15	3.00e-55	206.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	61.49	7.00e-54	202.00
IUUC-Cne-026864	Cryptococcus neoformans	63.70	2.00e-54	204.00
IUUC-Cme-027284	Cyanidioschyzon merolae	59.18	5.00e-43	167.00
IUUC-Dre-028774	Danio rerio	87.92	2.00e-73	267.00
IUUC-Dno-029661	Dasypus novemcinctus	92.62	2.00e-76	277.00
IUUC-Dor-030452	Dipodomys ordii	92.57	2.00e-75	273.00
IUUC-Dse-031487	Dothistroma septosporum	61.49	2.00e-53	200.00
IUUC-Dme-031863	Drosophila melanogaster	78.38	3.00e-65	239.00
IUUC-Ete-032595	Echinops telfairi	89.26	1.00e-73	267.00
IUUC-Eca-033377	Equus caballus	92.62	2.00e-76	277.00
IUUC-Eeu-035191	Erinaceus europaeus	70.27	9.00e-52	195.00
IUUC-Fca-036336	Felis catus	92.62	2.00e-76	277.00
IUUC-Fal-037474	Ficedula albicollis	86.92	4.00e-62	228.00
IUUC-Fox-037808	Fusarium oxysporum	61.49	1.00e-53	201.00
IUUC-Fso-038232	Fusarium solani	61.49	1.00e-53	201.00
IUUC-Gmo-038517	Gadus morhua	88.51	5.00e-73	265.00
IUUC-Ggr-039875	Gaeumannomyces graminis	61.64	6.00e-53	199.00
IUUC-Gga-040494	Gallus gallus	92.62	2.00e-76	277.00
IUUC-Gac-042471	Gasterosteus aculeatus	87.92	6.00e-74	268.00
IUUC-Gma-043865	Glycine max	70.55	2.00e-59	220.00
IUUC-Ggo-044580	Gorilla gorilla	92.62	4.00e-76	275.00
IUUC-Hsa-046239	Homo sapiens	92.62	2.00e-76	277.00
IUUC-Hvu-047054	Hordeum vulgare	69.18	4.00e-58	216.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	92.62	2.00e-76	277.00
IUUC-Kpa-049225	Komagataella pastoris	61.22	4.00e-51	193.00
IUUC-Lch-050283	Latimeria chalumnae	89.86	3.00e-74	269.00
IUUC-Lpe-051301	Leersia perrieri	70.55	5.00e-59	219.00
IUUC-Loc-051962	Lepisosteus oculatus	90.60	5.00e-75	272.00
IUUC-Laf-053380	Loxodonta africana	92.62	2.00e-76	277.00
IUUC-Mcc-054819	Macaca mulatta	92.62	6.00e-77	279.00
IUUC-Meu-056103	Macropus eugenii	92.57	2.00e-75	273.00
IUUC-Mor-057087	Magnaporthe oryzae	62.07	6.00e-52	195.00
IUUC-Mpo-057498	Magnaporthe poae	61.64	6.00e-53	199.00
IUUC-Mtr-058305	Medicago truncatula	70.55	2.00e-59	220.00
IUUC-Mla-058876	Melampsora laricipopulina	66.89	8.00e-49	185.00
IUUC-Mga-059863	Meleagris gallopavo	92.62	2.00e-76	276.00
IUUC-Mvi-060330	Microbotryum violaceum	65.99	2.00e-47	181.00
IUUC-Mmr-060630	Microcebus murinus	92.62	2.00e-76	277.00
IUUC-Mdo-062676	Monodelphis domestica	92.62	2.00e-76	277.00
IUUC-Mmu-063491	Mus musculus	92.62	2.00e-76	277.00
IUUC-Mac-064774	Musa acuminata	70.55	6.00e-59	219.00
IUUC-Mpu-065803	Mustela putorius furo	92.62	2.00e-76	277.00
IUUC-Mlu-067147	Myotis lucifugus	92.62	2.00e-76	277.00
IUUC-Nfi-068580	Neosartorya fischeri	61.49	3.00e-53	199.00
IUUC-Ncr-068913	Neurospora crassa	61.49	6.00e-54	202.00
IUUC-Nle-070105	Nomascus leucogenys	92.62	2.00e-76	277.00
IUUC-Opr-070935	Ochotona princeps	92.62	2.00e-76	277.00
IUUC-Ont-071335	Oreochromis niloticus	87.92	1.00e-73	268.00
IUUC-Oan-072706	Ornithorhynchus anatinus	92.62	2.00e-76	276.00
IUUC-Ocu-074130	Oryctolagus cuniculus	92.62	2.00e-76	277.00
IUUC-Oba-075896	Oryza barthii	69.86	2.00e-58	217.00
IUUC-Obr-076713	Oryza brachyantha	70.55	5.00e-59	219.00
IUUC-Ogl-077116	Oryza glaberrima	70.55	5.00e-59	219.00
IUUC-Ogu-078696	Oryza glumaepatula	70.55	5.00e-59	219.00
IUUC-Oin-079099	Oryza indica	70.55	5.00e-59	219.00
IUUC-Olo-081018	Oryza longistaminata	62.09	8.00e-53	199.00
IUUC-Ome-081285	Oryza meridionalis	70.55	5.00e-59	219.00
IUUC-Oni-082088	Oryza nivara	70.55	5.00e-59	219.00
IUUC-Opu-083310	Oryza punctata	70.55	5.00e-59	219.00
IUUC-Oru-084449	Oryza rufipogon	70.55	5.00e-59	219.00
IUUC-Osa-085923	Oryza sativa	70.55	5.00e-59	219.00
IUUC-Ola-087160	Oryzias latipes	87.92	1.00e-73	268.00
IUUC-Olu-087830	Ostreococcus lucimarinus	71.23	4.00e-50	189.00
IUUC-Oga-088836	Otolemur garnettii	92.62	2.00e-76	277.00
IUUC-Oar-090141	Ovis aries	92.62	2.00e-76	277.00
IUUC-Ptr-091453	Pan troglodytes	92.62	2.00e-76	277.00
IUUC-Pan-092511	Papio anubis	92.62	2.00e-76	277.00
IUUC-Psi-093968	Pelodiscus sinensis	91.95	2.00e-76	276.00
IUUC-Pma-094239	Petromyzon marinus	87.16	3.00e-72	263.00
IUUC-Pno-094935	Phaeosphaeria nodorum	61.49	6.00e-54	202.00
IUUC-Ppa-095689	Physcomitrella patens	71.23	5.00e-50	189.00
IUUC-Pfo-096496	Poecilia formosa	87.92	6.00e-74	268.00
IUUC-Pab-098121	Pongo abelii	92.62	2.00e-76	277.00
IUUC-Pop-099517	Populus trichocarpa	70.55	3.00e-59	219.00
IUUC-Pca-100906	Procavia capensis	81.76	3.00e-65	239.00
IUUC-Ppe-101594	Prunus persica	70.55	6.00e-59	219.00
IUUC-Pva-102380	Pteropus vampyrus	87.16	2.00e-71	260.00
IUUC-Pgr-103611	Puccinia graminis	66.22	5.00e-49	186.00
IUUC-Ptt-103971	Puccinia triticina	66.67	1.00e-41	161.00
IUUC-Pte-104378	Pyrenophora teres	62.16	3.00e-54	203.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	62.16	3.00e-54	203.00
IUUC-Rno-105772	Rattus norvegicus	92.62	5.00e-77	279.00
IUUC-Sce-106283	Saccharomyces cerevisiae	61.64	2.00e-51	194.00
IUUC-Sha-107650	Sarcophilus harrisii	91.28	1.00e-74	271.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	64.38	6.00e-48	182.00
IUUC-Spo-108073	Schizosaccharomyces pombe	64.38	4.00e-48	182.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	61.74	3.00e-54	202.00
IUUC-Smo-109036	Selaginella moellendorffii	71.23	2.00e-59	220.00
IUUC-Sit-110731	Setaria italica	70.55	5.00e-59	219.00
IUUC-Sly-111506	Solanum lycopersicum	71.23	2.00e-59	220.00
IUUC-Stu-112080	Solanum tuberosum	71.23	2.00e-59	220.00
IUUC-Sar-113429	Sorex araneus	92.62	2.00e-76	277.00
IUUC-Sbi-114289	Sorghum bicolor	70.55	5.00e-59	219.00
IUUC-Sre-115106	Sporisorium reilianum	68.92	4.00e-50	190.00
IUUC-Ssc-115257	Sus scrofa	90.60	2.00e-74	270.00
IUUC-Tgu-116604	Taeniopygia guttata	95.30	1.00e-80	290.00
IUUC-Tru-117924	Takifugu rubripes	89.26	5.00e-69	252.00
IUUC-Tsy-119000	Tarsius syrichta	92.62	2.00e-76	277.00
IUUC-Tni-119745	Tetraodon nigroviridis	87.25	2.00e-72	263.00
IUUC-Tca-121827	Theobroma cacao	70.55	2.00e-59	220.00
IUUC-Tre-122002	Trichoderma reesei	61.49	1.00e-53	201.00
IUUC-Tvi-122331	Trichoderma virens	61.49	1.00e-53	201.00
IUUC-Tae-125807	Triticum aestivum	69.86	1.00e-58	218.00
IUUC-Tur-126866	Triticum urartu	69.86	1.00e-58	218.00
IUUC-Tme-127148	Tuber melanosporum	63.70	6.00e-54	202.00
IUUC-Tbe-127921	Tupaia belangeri	90.60	3.00e-72	263.00
IUUC-Ttr-129121	Tursiops truncatus	92.62	2.00e-76	277.00
IUUC-Uma-129561	Ustilago maydis	68.92	2.00e-50	190.00
IUUC-Vda-129711	Verticillium dahliae	61.49	7.00e-54	202.00
IUUC-Vpa-130570	Vicugna pacos	86.49	1.00e-68	250.00
IUUC-Vvi-131108	Vitis vinifera	71.92	8.00e-60	221.00
IUUC-Xtr-131824	Xenopus tropicalis	91.28	3.00e-75	273.00
IUUC-Xma-133667	Xiphophorus maculatus	87.92	1.00e-73	268.00
IUUC-Yli-134660	Yarrowia lipolytica	58.78	1.00e-52	197.00
IUUC-Zma-135627	Zea mays	64.33	1.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence