iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053865

UUCD1 version

UUC-LoA-00586

Ensembl Protein ID

ENSLAFP00000014254.3

UniProt Accession

G3TI13; G3TI13_LOXAF

Protein Name

Uncharacterized protein

Gene Name

GNB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000017004.3	ENSLAFT00000017002.3	ENSLAFP00000014254.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-40	134.1	213	251
UBD/Beta-Prp	1.60e-52	178.9	78	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 213  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 251
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  ++ l+t++     
   Q: 78   TRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRv 166
           5689*****************************************************************************99877666 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + +n ++++s D+t+ lWd++tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t+
   Q: 167  srELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 253
           779*************99.7778999********************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +gh++ ++ v+f+pn+  + +gs+D + r++dlr ++ l ++++ n
   Q: 254  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 299
           ***************************************9999854 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

PGLGPAARSC LPQPPSRGPQ PPPTPPHGPG AMSELEQLRQ EAEQLRNQIR DARKACGDST 60
LTQITAGLDP VGRIQMRTRR TLRGHLAKIY AMHWGTDSRL LVSASQDGKL IIWDSYTTNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGCCTCG GGCCAGCGGC GAGGAGCTGC CTCCCCCAGC CCCCGTCCCG CGGCCCCCAG 60
CCGCCCCCAA CCCCGCCCCA CGGGCCCGGC GCCATGAGTG AGCTGGAGCA ACTGAGACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000161	Aegilops tauschii	50.19	6.00e-74	271.00
IUUC-Aml-001395	Ailuropoda melanoleuca	99.07	0.00e+00	656.00
IUUC-Ago-007831	Ashbya gossypii	38.24	4.00e-68	251.00
IUUC-Ate-010520	Aspergillus terreus	61.13	5.00e-109	387.00
IUUC-Ame-011124	Astyanax mexicanus	94.12	0.00e+00	637.00
IUUC-Bgr-012079	Blumeria graminis	65.19	6.00e-132	463.00
IUUC-Bta-013430	Bos taurus	100.00	0.00e+00	665.00
IUUC-Cel-018704	Caenorhabditis elegans	85.29	9.00e-180	622.00
IUUC-Cja-019794	Callithrix jacchus	100.00	0.00e+00	665.00
IUUC-Cfa-020395	Canis familiaris	89.47	2.00e-176	611.00
IUUC-Cpo-021865	Cavia porcellus	100.00	0.00e+00	681.00
IUUC-Csa-023572	Chlorocebus sabaeus	100.00	0.00e+00	665.00
IUUC-Cho-024766	Choloepus hoffmanni	88.92	6.00e-177	612.00
IUUC-Cin-025309	Ciona intestinalis	79.47	1.00e-169	588.00
IUUC-Csv-026258	Ciona savignyi	79.77	8.00e-170	589.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	65.50	6.00e-136	476.00
IUUC-Dre-027957	Danio rerio	94.43	0.00e+00	634.00
IUUC-Dno-029001	Dasypus novemcinctus	99.46	0.00e+00	681.00
IUUC-Dor-030322	Dipodomys ordii	88.85	2.00e-166	577.00
IUUC-Dse-031388	Dothistroma septosporum	66.18	3.00e-137	481.00
IUUC-Dme-031748	Drosophila melanogaster	81.47	2.00e-172	597.00
IUUC-Ete-032710	Echinops telfairi	88.64	8.00e-167	578.00
IUUC-Eca-034149	Equus caballus	100.00	0.00e+00	665.00
IUUC-Eeu-034978	Erinaceus europaeus	87.91	2.00e-144	504.00
IUUC-Fca-036537	Felis catus	100.00	0.00e+00	665.00
IUUC-Fox-037946	Fusarium oxysporum	65.79	4.00e-131	460.00
IUUC-Fso-038136	Fusarium solani	65.79	4.00e-131	460.00
IUUC-Gmo-039332	Gadus morhua	94.74	0.00e+00	633.00
IUUC-Ggr-039969	Gaeumannomyces graminis	65.20	1.00e-134	472.00
IUUC-Gac-041932	Gasterosteus aculeatus	93.19	0.00e+00	628.00
IUUC-Ggo-044543	Gorilla gorilla	100.00	0.00e+00	665.00
IUUC-Hsa-046432	Homo sapiens	100.00	0.00e+00	665.00
IUUC-Itr-048049	Ictidomys tridecemlineatus	100.00	0.00e+00	687.00
IUUC-Kpa-049192	Komagataella pastoris	38.06	2.00e-62	232.00
IUUC-Mcc-055781	Macaca mulatta	96.72	0.00e+00	632.00
IUUC-Meu-056902	Macropus eugenii	99.38	0.00e+00	662.00
IUUC-Mor-057188	Magnaporthe oryzae	64.91	5.00e-134	470.00
IUUC-Mpo-057544	Magnaporthe poae	64.91	6.00e-135	473.00
IUUC-Mla-059086	Melampsora laricipopulina	70.62	2.00e-149	521.00
IUUC-Mmr-061015	Microcebus murinus	100.00	0.00e+00	665.00
IUUC-Mdo-062734	Monodelphis domestica	99.38	0.00e+00	662.00
IUUC-Mmu-063737	Mus musculus	100.00	0.00e+00	681.00
IUUC-Mpu-066784	Mustela putorius furo	99.68	0.00e+00	637.00
IUUC-Mlu-067912	Myotis lucifugus	99.69	0.00e+00	663.00
IUUC-Ncr-068650	Neurospora crassa	64.62	6.00e-128	450.00
IUUC-Nle-069612	Nomascus leucogenys	89.47	1.00e-176	611.00
IUUC-Opr-070866	Ochotona princeps	100.00	0.00e+00	665.00
IUUC-Ont-072526	Oreochromis niloticus	93.50	0.00e+00	628.00
IUUC-Ocu-074344	Oryctolagus cuniculus	100.00	0.00e+00	665.00
IUUC-Oga-089046	Otolemur garnettii	100.00	0.00e+00	665.00
IUUC-Oar-089822	Ovis aries	93.50	6.00e-177	612.00
IUUC-Ptr-091444	Pan troglodytes	100.00	0.00e+00	665.00
IUUC-Pan-092045	Papio anubis	100.00	0.00e+00	665.00
IUUC-Pma-094748	Petromyzon marinus	90.87	6.00e-139	486.00
IUUC-Pab-097601	Pongo abelii	99.07	0.00e+00	658.00
IUUC-Pca-100940	Procavia capensis	100.00	0.00e+00	665.00
IUUC-Pva-102229	Pteropus vampyrus	99.69	0.00e+00	658.00
IUUC-Rno-106104	Rattus norvegicus	100.00	0.00e+00	665.00
IUUC-Sha-107632	Sarcophilus harrisii	99.38	0.00e+00	662.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.91	3.00e-58	218.00
IUUC-Smo-109652	Selaginella moellendorffii	42.86	2.00e-73	269.00
IUUC-Sar-113642	Sorex araneus	91.54	2.00e-150	525.00
IUUC-Ssc-115595	Sus scrofa	100.00	0.00e+00	665.00
IUUC-Tru-118401	Takifugu rubripes	93.19	0.00e+00	628.00
IUUC-Tsy-119354	Tarsius syrichta	87.62	7.00e-174	602.00
IUUC-Tni-120216	Tetraodon nigroviridis	92.88	0.00e+00	627.00
IUUC-Tre-122156	Trichoderma reesei	65.50	3.00e-135	474.00
IUUC-Tvi-122640	Trichoderma virens	65.50	3.00e-135	474.00
IUUC-Tbe-128132	Tupaia belangeri	99.22	3.00e-148	516.00
IUUC-Ttr-128403	Tursiops truncatus	100.00	0.00e+00	665.00
IUUC-Vda-129855	Verticillium dahliae	70.16	6.00e-129	453.00
IUUC-Vpa-130474	Vicugna pacos	97.79	4.00e-76	277.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence