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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018226
Ensembl Protein ID Y74C10AR.1a
UniProt Accession Q965S8; EIF3I_CAEEL
Genbank Protein ID CCD73538.1
Protein Name Eukaryotic translation initiation factor 3 subunit I
Genbank Nucleotide ID FO081786
Gene Name eif-3.I; Y74C10AR.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00001232 Y74C10AR.1a Y74C10AR.1a
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-16 59.3 50 87
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+++  ++ d t  v++s+D t+k+WD   g++l
   Q: 50   GHNGAVWDIdvSW-DtTKCVTASGDLTVKIWDAELGNCL 87
           8*******73377.55****************7766665 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Protein Sequence
(Fasta)
MRPLSLKGHE RALTRVRFNR EGDLTFSCAK DKKPCVWYTE NGERIGSYDG HNGAVWDIDV 60
SWDTTKCVTA SGDLTVKIWD AELGNCLYTI NHQTPMKSCG FSYSGNLVCF TTQKMTKNLS 120
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Protein Fasta Sequence


>IUUC-Cel-018226|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATGCGTCCA CTTTCGCTGA AAGGCCACGA ACGTGCTCTC ACTCGGGTCC GTTTCAATCG 60
TGAGGGAGAT TTGACGTTCT CCTGTGCTAA GGACAAGAAG CCATGCGTTT GGTATACTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018226|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
KEGG cel:CELE_Y74C10AR.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000115 Aegilops tauschii 46.49 2.00e-26 112.00
IUUC-Aml-001321 Ailuropoda melanoleuca 42.77 5.00e-82 296.00
IUUC-Atr-002468 Amborella trichopoda 34.17 2.00e-36 144.00
IUUC-Apl-003841 Anas platyrhynchos 43.25 2.00e-81 294.00
IUUC-Aca-005123 Anolis carolinensis 42.64 3.00e-82 297.00
IUUC-Aly-005473 Arabidopsis lyrata 37.96 4.00e-67 246.00
IUUC-Ath-007094 Arabidopsis thaliana 38.27 5.00e-67 246.00
IUUC-Ago-008000 Ashbya gossypii 36.75 3.00e-64 237.00
IUUC-Acl-008098 Aspergillus clavatus 40.66 5.00e-74 270.00
IUUC-Afl-008494 Aspergillus flavus 41.03 5.00e-76 276.00
IUUC-Afu-009080 Aspergillus fumigatus 40.36 4.00e-75 273.00
IUUC-Ani-009230 Aspergillus nidulans 41.16 3.00e-76 277.00
IUUC-Ang-009593 Aspergillus niger 22.54 7.00e-13 67.00
IUUC-Aor-010114 Aspergillus oryzae 41.03 5.00e-76 276.00
IUUC-Ate-010285 Aspergillus terreus 41.46 2.00e-76 278.00
IUUC-Ame-011534 Astyanax mexicanus 43.08 1.00e-81 295.00
IUUC-Bgr-012121 Blumeria graminis 39.82 4.00e-71 259.00
IUUC-Bta-013143 Bos taurus 42.94 8.00e-83 298.00
IUUC-Bci-013950 Botrytis cinerea 42.20 5.00e-78 283.00
IUUC-Bdi-015019 Brachypodium distachyon 40.06 4.00e-71 260.00
IUUC-Bol-015709 Brassica oleracea 38.72 1.00e-65 243.00
IUUC-Bra-018077 Brassica rapa 37.94 1.00e-66 245.00
IUUC-Cja-019741 Callithrix jacchus 43.25 2.00e-83 300.00
IUUC-Cfa-021204 Canis familiaris 42.77 3.00e-82 296.00
IUUC-Cpo-021661 Cavia porcellus 43.08 1.00e-82 298.00
IUUC-Cre-022952 Chlamydomonas reinhardtii 41.59 5.00e-79 286.00
IUUC-Csa-024038 Chlorocebus sabaeus 43.25 2.00e-83 300.00
IUUC-Cin-025597 Ciona intestinalis 45.57 2.00e-89 320.00
IUUC-Csv-026287 Ciona savignyi 24.69 2.00e-24 105.00
IUUC-Cgl-026583 Colletotrichum gloeosporioides 42.25 6.00e-75 273.00
IUUC-Cne-026838 Cryptococcus neoformans 39.94 4.00e-73 266.00
IUUC-Cme-027304 Cyanidioschyzon merolae 35.60 3.00e-58 217.00
IUUC-Dre-028567 Danio rerio 43.03 1.00e-81 294.00
IUUC-Dno-029171 Dasypus novemcinctus 43.08 4.00e-82 297.00
IUUC-Dor-030257 Dipodomys ordii 33.52 2.00e-27 115.00
IUUC-Dse-031191 Dothistroma septosporum 41.03 7.00e-72 262.00
IUUC-Dme-031879 Drosophila melanogaster 45.34 1.00e-89 321.00
IUUC-Ete-032336 Echinops telfairi 39.91 7.00e-45 172.00
IUUC-Eca-033259 Equus caballus 42.77 4.00e-82 296.00
IUUC-Eeu-035153 Erinaceus europaeus 36.55 6.00e-23 100.00
IUUC-Fca-036489 Felis catus 42.77 4.00e-82 296.00
IUUC-Fal-037485 Ficedula albicollis 42.94 3.00e-81 293.00
IUUC-Fox-037860 Fusarium oxysporum 40.43 2.00e-73 268.00
IUUC-Fso-038188 Fusarium solani 40.43 4.00e-72 263.00
IUUC-Gmo-039311 Gadus morhua 43.17 1.00e-80 291.00
IUUC-Ggr-040045 Gaeumannomyces graminis 43.20 1.00e-76 278.00
IUUC-Gga-040645 Gallus gallus 42.39 4.00e-80 290.00
IUUC-Gac-042086 Gasterosteus aculeatus 43.65 8.00e-81 292.00
IUUC-Gma-043930 Glycine max 40.85 5.00e-72 263.00
IUUC-Ggo-045578 Gorilla gorilla 43.25 2.00e-83 300.00
IUUC-Hsa-046734 Homo sapiens 43.25 2.00e-83 300.00
IUUC-Hvu-047553 Hordeum vulgare 39.75 2.00e-71 261.00
IUUC-Itr-048467 Ictidomys tridecemlineatus 43.38 4.00e-83 300.00
IUUC-Kpa-049325 Komagataella pastoris 41.03 4.00e-74 270.00
IUUC-Lch-049620 Latimeria chalumnae 43.14 2.00e-74 271.00
IUUC-Lpe-051338 Leersia perrieri 40.50 1.00e-69 254.00
IUUC-Loc-052094 Lepisosteus oculatus 39.88 8.00e-70 255.00
IUUC-Lma-053047 Leptosphaeria maculans 41.64 2.00e-75 274.00
IUUC-Laf-053801 Loxodonta africana 43.26 1.00e-80 291.00
IUUC-Mcc-055498 Macaca mulatta 38.11 8.00e-64 235.00
IUUC-Meu-056729 Macropus eugenii 39.33 5.00e-72 263.00
IUUC-Mor-057025 Magnaporthe oryzae 42.60 2.00e-76 277.00
IUUC-Mpo-057511 Magnaporthe poae 43.50 8.00e-77 279.00
IUUC-Mtr-058051 Medicago truncatula 39.51 1.00e-68 251.00
IUUC-Mla-059061 Melampsora laricipopulina 38.75 2.00e-66 244.00
IUUC-Mga-059229 Meleagris gallopavo 42.68 3.00e-79 286.00
IUUC-Mvi-060399 Microbotryum violaceum 38.62 1.00e-66 244.00
IUUC-Mmr-060764 Microcebus murinus 42.94 5.00e-83 299.00
IUUC-Mdo-062088 Monodelphis domestica 42.20 6.00e-81 292.00
IUUC-Mmu-064304 Mus musculus 43.56 2.00e-83 301.00
IUUC-Mac-065520 Musa acuminata 41.38 3.00e-70 256.00
IUUC-Mpu-066340 Mustela putorius furo 42.77 4.00e-82 296.00
IUUC-Mlu-067111 Myotis lucifugus 43.08 7.00e-83 299.00
IUUC-Nfi-068478 Neosartorya fischeri 40.42 2.00e-74 271.00
IUUC-Ncr-068820 Neurospora crassa 41.74 1.00e-74 271.00
IUUC-Nle-069903 Nomascus leucogenys 43.08 3.00e-82 296.00
IUUC-Opr-070221 Ochotona princeps 42.33 8.00e-81 292.00
IUUC-Ont-071765 Oreochromis niloticus 43.65 3.00e-82 296.00
IUUC-Oan-073660 Ornithorhynchus anatinus 42.32 9.00e-69 251.00
IUUC-Ocu-074039 Oryctolagus cuniculus 43.08 1.00e-82 298.00
IUUC-Oba-075395 Oryza barthii 35.09 5.00e-57 213.00
IUUC-Obr-076334 Oryza brachyantha 37.27 2.00e-63 234.00
IUUC-Ogl-077060 Oryza glaberrima 41.05 6.00e-72 262.00
IUUC-Ogu-078207 Oryza glumaepatula 40.68 2.00e-73 267.00
IUUC-Oin-079878 Oryza indica 40.92 2.00e-72 264.00
IUUC-Olo-080677 Oryza longistaminata 33.78 1.00e-62 232.00
IUUC-Ome-081228 Oryza meridionalis 32.31 6.00e-40 155.00
IUUC-Oni-082411 Oryza nivara 35.60 2.00e-55 207.00
IUUC-Opu-083136 Oryza punctata 39.75 6.00e-72 262.00
IUUC-Oru-084916 Oryza rufipogon 39.88 3.00e-72 263.00
IUUC-Osa-085454 Oryza sativa 40.92 2.00e-72 264.00
IUUC-Ola-087053 Oryzias latipes 42.11 2.00e-81 293.00
IUUC-Olu-087602 Ostreococcus lucimarinus 43.17 8.00e-78 282.00
IUUC-Oga-088154 Otolemur garnettii 43.08 1.00e-82 298.00
IUUC-Oar-089915 Ovis aries 42.77 4.00e-82 296.00
IUUC-Ptr-091124 Pan troglodytes 37.96 1.00e-59 222.00
IUUC-Pan-092035 Papio anubis 43.25 2.00e-83 300.00
IUUC-Psi-094096 Pelodiscus sinensis 40.00 2.00e-43 167.00
IUUC-Pma-094255 Petromyzon marinus 25.00 5.00e-19 87.00
IUUC-Pno-094988 Phaeosphaeria nodorum 39.76 5.00e-66 243.00
IUUC-Ppa-095536 Physcomitrella patens 42.06 5.00e-75 273.00
IUUC-Pfo-096101 Poecilia formosa 42.72 1.00e-81 295.00
IUUC-Pab-097726 Pongo abelii 43.25 2.00e-83 300.00
IUUC-Pop-099665 Populus trichocarpa 41.74 5.00e-71 259.00
IUUC-Pca-101014 Procavia capensis 43.25 2.00e-83 300.00
IUUC-Ppe-101320 Prunus persica 39.13 3.00e-70 257.00
IUUC-Pva-102789 Pteropus vampyrus 40.18 2.00e-75 274.00
IUUC-Pgr-103479 Puccinia graminis 37.50 1.00e-66 245.00
IUUC-Ptt-103981 Puccinia triticina 37.93 4.00e-67 246.00
IUUC-Pte-104278 Pyrenophora teres 41.64 1.00e-73 268.00
IUUC-Pyt-104492 Pyrenophora triticirepentis 41.64 1.00e-73 268.00
IUUC-Rno-105867 Rattus norvegicus 40.06 6.00e-68 249.00
IUUC-Sce-106251 Saccharomyces cerevisiae 40.24 6.00e-74 269.00
IUUC-Sha-107039 Sarcophilus harrisii 42.20 7.00e-81 292.00
IUUC-Sja-107758 Schizosaccharomyces japonicus 39.82 4.00e-71 259.00
IUUC-Spo-108314 Schizosaccharomyces pombe 37.27 5.00e-67 246.00
IUUC-Ssl-108478 Sclerotinia sclerotiorum 41.90 2.00e-77 281.00
IUUC-Smo-108728 Selaginella moellendorffii 40.19 1.00e-72 265.00
IUUC-Sit-110801 Setaria italica 40.06 9.00e-72 262.00
IUUC-Sly-111326 Solanum lycopersicum 40.43 1.00e-71 261.00
IUUC-Stu-112458 Solanum tuberosum 40.12 9.00e-71 258.00
IUUC-Sbi-114063 Sorghum bicolor 39.14 2.00e-70 257.00
IUUC-Sre-115096 Sporisorium reilianum 40.84 1.00e-65 241.00
IUUC-Ssc-116080 Sus scrofa 42.94 7.00e-83 299.00
IUUC-Tgu-116988 Taeniopygia guttata 43.25 9.00e-82 295.00
IUUC-Tru-118766 Takifugu rubripes 43.69 9.00e-82 295.00
IUUC-Tsy-119522 Tarsius syrichta 26.90 5.00e-19 87.00
IUUC-Tni-120197 Tetraodon nigroviridis 43.65 9.00e-83 298.00
IUUC-Tca-121316 Theobroma cacao 41.69 2.00e-73 268.00
IUUC-Tre-122097 Trichoderma reesei 41.69 9.00e-75 272.00
IUUC-Tvi-122442 Trichoderma virens 41.99 2.00e-75 274.00
IUUC-Tae-125800 Triticum aestivum 39.44 1.00e-70 259.00
IUUC-Tur-126334 Triticum urartu 32.72 7.00e-50 189.00
IUUC-Tme-127038 Tuber melanosporum 40.98 4.00e-76 276.00
IUUC-Ttr-128659 Tursiops truncatus 40.18 2.00e-65 241.00
IUUC-Uma-129464 Ustilago maydis 41.44 3.00e-66 243.00
IUUC-Vda-129841 Verticillium dahliae 42.55 1.00e-76 278.00
IUUC-Vpa-130382 Vicugna pacos 25.95 5.00e-21 94.00
IUUC-Vvi-131076 Vitis vinifera 41.64 3.00e-72 263.00
IUUC-Xtr-132395 Xenopus tropicalis 41.72 1.00e-79 288.00
IUUC-Xma-133383 Xiphophorus maculatus 42.72 1.00e-81 295.00
IUUC-Yli-134586 Yarrowia lipolytica 40.73 5.00e-66 243.00
IUUC-Zma-135904 Zea mays 40.06 3.00e-71 260.00
Created Date 25-Jun-2017

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