iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052094

Ensembl Protein ID

ENSLOCP00000002853.1

UniProt Accession

W5M395; W5M395_LEPOC

Genbank Protein ID

ENSLOCP00000002853

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Genbank Nucleotide ID

AHAT01009463

Gene Name

eif3i; EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000002433.1	ENSLOCT00000002859.1	ENSLOCP00000002853.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-20	72.2	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d + +++Gs D+++++WD  tg++l
   Q: 50   GHTGAVWCVdvDW-DtKNVLTGSADNSCRLWDCETGKQL 87
           8*******63377.4488*****************9986 PP

Organism

Lepisosteus oculatus

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

QKPILLQGHE RSITQIKYNR EGDLLFSVAK DTVVNVWYSV NGERLGTYNG HTGAVWCVDV 60
DWDTKNVLTG SADNSCRLWD CETGKQLAFL KTSSAVRTCG FDFSGNIIMF STDKQMGYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAAACCCA TTCTTCTGCA GGGCCATGAA CGGTCCATCA CACAGATCAA GTACAACCGA 60
GAAGGAGACC TGCTCTTCTC CGTGGCTAAA GACACAGTAC GAGATTCCTT GAGTTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0001889--P:liver development
GO:0006446--P:regulation of translational initiation
GO:0002040--P:sprouting angiogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001321	Ailuropoda melanoleuca	79.32	3.00e-157	547.00
IUUC-Atr-002468	Amborella trichopoda	45.05	3.00e-40	157.00
IUUC-Apl-003841	Anas platyrhynchos	81.17	5.00e-162	563.00
IUUC-Aca-005123	Anolis carolinensis	80.80	2.00e-160	558.00
IUUC-Aly-006532	Arabidopsis lyrata	41.41	4.00e-70	258.00
IUUC-Ath-007094	Arabidopsis thaliana	41.28	8.00e-73	267.00
IUUC-Ago-008000	Ashbya gossypii	38.69	6.00e-67	247.00
IUUC-Acl-008098	Aspergillus clavatus	48.64	4.00e-86	311.00
IUUC-Afl-008494	Aspergillus flavus	47.24	9.00e-86	310.00
IUUC-Afu-009080	Aspergillus fumigatus	47.13	1.00e-85	309.00
IUUC-Ani-009230	Aspergillus nidulans	47.40	1.00e-85	309.00
IUUC-Aor-010114	Aspergillus oryzae	47.24	9.00e-86	310.00
IUUC-Ate-010285	Aspergillus terreus	48.62	3.00e-88	318.00
IUUC-Ame-011534	Astyanax mexicanus	82.77	4.00e-164	570.00
IUUC-Bgr-012121	Blumeria graminis	41.90	1.00e-72	266.00
IUUC-Bta-013143	Bos taurus	79.26	2.00e-156	544.00
IUUC-Bci-013950	Botrytis cinerea	45.40	5.00e-83	300.00
IUUC-Bdi-015019	Brachypodium distachyon	44.58	2.00e-75	275.00
IUUC-Bol-015709	Brassica oleracea	40.30	3.00e-68	253.00
IUUC-Bra-017760	Brassica rapa	40.30	1.00e-68	254.00
IUUC-Cel-018226	Caenorhabditis elegans	39.88	2.00e-69	255.00
IUUC-Cja-019741	Callithrix jacchus	79.26	1.00e-156	545.00
IUUC-Cfa-021204	Canis familiaris	79.01	6.00e-157	546.00
IUUC-Cpo-021661	Cavia porcellus	79.63	1.00e-157	548.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	40.74	4.00e-70	258.00
IUUC-Csa-024038	Chlorocebus sabaeus	79.26	1.00e-156	545.00
IUUC-Cin-025597	Ciona intestinalis	55.86	5.00e-106	377.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.71	2.00e-79	288.00
IUUC-Cne-026838	Cryptococcus neoformans	44.71	4.00e-79	288.00
IUUC-Cme-027304	Cyanidioschyzon merolae	39.69	1.00e-72	266.00
IUUC-Dre-028567	Danio rerio	83.90	1.00e-166	578.00
IUUC-Dno-029171	Dasypus novemcinctus	79.57	1.00e-156	546.00
IUUC-Dor-030257	Dipodomys ordii	72.57	2.00e-74	272.00
IUUC-Dse-031191	Dothistroma septosporum	44.98	5.00e-78	284.00
IUUC-Dme-031879	Drosophila melanogaster	56.00	3.00e-106	377.00
IUUC-Ete-032336	Echinops telfairi	71.50	5.00e-90	323.00
IUUC-Eca-033259	Equus caballus	79.32	2.00e-157	547.00
IUUC-Eeu-035153	Erinaceus europaeus	50.68	5.00e-32	131.00
IUUC-Fca-036489	Felis catus	79.32	2.00e-157	547.00
IUUC-Fal-037485	Ficedula albicollis	81.79	6.00e-163	566.00
IUUC-Fox-037860	Fusarium oxysporum	43.20	6.00e-79	287.00
IUUC-Fso-038188	Fusarium solani	44.41	1.00e-78	286.00
IUUC-Gmo-039311	Gadus morhua	84.52	2.00e-167	581.00
IUUC-Ggr-040045	Gaeumannomyces graminis	44.79	6.00e-82	297.00
IUUC-Gga-040645	Gallus gallus	79.15	3.00e-159	554.00
IUUC-Gac-042086	Gasterosteus aculeatus	82.35	3.00e-162	563.00
IUUC-Gma-043246	Glycine max	40.92	9.00e-73	266.00
IUUC-Ggo-045578	Gorilla gorilla	79.26	1.00e-156	545.00
IUUC-Hsa-046734	Homo sapiens	79.26	1.00e-156	545.00
IUUC-Hvu-047553	Hordeum vulgare	41.72	3.00e-74	271.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	79.01	7.00e-157	546.00
IUUC-Kpa-049325	Komagataella pastoris	41.39	7.00e-72	264.00
IUUC-Lch-049620	Latimeria chalumnae	79.12	2.00e-144	504.00
IUUC-Lpe-051338	Leersia perrieri	40.19	8.00e-67	246.00
IUUC-Lma-053047	Leptosphaeria maculans	43.73	4.00e-78	284.00
IUUC-Laf-053801	Loxodonta africana	78.86	6.00e-153	533.00
IUUC-Mcc-055498	Macaca mulatta	69.66	4.00e-126	444.00
IUUC-Meu-056729	Macropus eugenii	72.53	5.00e-140	489.00
IUUC-Mor-057025	Magnaporthe oryzae	44.48	2.00e-78	286.00
IUUC-Mpo-057511	Magnaporthe poae	45.40	2.00e-81	295.00
IUUC-Mtr-058051	Medicago truncatula	42.51	4.00e-73	268.00
IUUC-Mla-059061	Melampsora laricipopulina	43.93	8.00e-72	263.00
IUUC-Mga-059229	Meleagris gallopavo	80.37	1.00e-159	555.00
IUUC-Mvi-060399	Microbotryum violaceum	41.99	1.00e-68	253.00
IUUC-Mmr-060764	Microcebus murinus	79.57	4.00e-157	546.00
IUUC-Mdo-062088	Monodelphis domestica	79.38	8.00e-158	549.00
IUUC-Mmu-064304	Mus musculus	79.57	9.00e-157	545.00
IUUC-Mac-065520	Musa acuminata	43.34	9.00e-76	276.00
IUUC-Mpu-066340	Mustela putorius furo	79.32	2.00e-157	547.00
IUUC-Mlu-067111	Myotis lucifugus	79.32	2.00e-157	548.00
IUUC-Nfi-068478	Neosartorya fischeri	46.83	2.00e-85	309.00
IUUC-Ncr-068820	Neurospora crassa	44.79	1.00e-79	290.00
IUUC-Nle-069903	Nomascus leucogenys	79.32	1.00e-157	548.00
IUUC-Opr-070221	Ochotona princeps	77.09	5.00e-151	526.00
IUUC-Ont-071765	Oreochromis niloticus	85.76	2.00e-168	584.00
IUUC-Oan-073660	Ornithorhynchus anatinus	78.50	3.00e-141	494.00
IUUC-Ocu-074039	Oryctolagus cuniculus	79.32	2.00e-157	548.00
IUUC-Oba-075395	Oryza barthii	39.51	2.00e-69	255.00
IUUC-Obr-076334	Oryza brachyantha	38.15	8.00e-66	243.00
IUUC-Ogl-077060	Oryza glaberrima	41.28	2.00e-71	262.00
IUUC-Ogu-078207	Oryza glumaepatula	41.67	2.00e-73	269.00
IUUC-Oin-079878	Oryza indica	41.23	6.00e-73	267.00
IUUC-Olo-080677	Oryza longistaminata	36.15	6.00e-68	251.00
IUUC-Ome-081228	Oryza meridionalis	33.47	3.00e-33	135.00
IUUC-Oni-082411	Oryza nivara	39.94	3.00e-69	254.00
IUUC-Opu-083136	Oryza punctata	40.92	1.00e-72	266.00
IUUC-Oru-084916	Oryza rufipogon	40.12	2.00e-70	259.00
IUUC-Osa-085454	Oryza sativa	41.23	6.00e-73	267.00
IUUC-Ola-087053	Oryzias latipes	86.07	4.00e-168	583.00
IUUC-Olu-087602	Ostreococcus lucimarinus	43.38	7.00e-74	270.00
IUUC-Oga-088154	Otolemur garnettii	79.01	1.00e-156	545.00
IUUC-Oar-089915	Ovis aries	79.32	4.00e-157	546.00
IUUC-Ptr-091124	Pan troglodytes	62.19	5.00e-113	400.00
IUUC-Pan-092035	Papio anubis	79.26	1.00e-156	545.00
IUUC-Psi-094096	Pelodiscus sinensis	74.07	6.00e-95	339.00
IUUC-Pno-094988	Phaeosphaeria nodorum	40.62	2.00e-66	245.00
IUUC-Ppa-095536	Physcomitrella patens	43.93	1.00e-76	280.00
IUUC-Pfo-096101	Poecilia formosa	84.83	2.00e-167	581.00
IUUC-Pab-097726	Pongo abelii	79.26	1.00e-156	545.00
IUUC-Pop-099617	Populus trichocarpa	42.77	5.00e-75	274.00
IUUC-Pca-101014	Procavia capensis	79.26	1.00e-156	545.00
IUUC-Ppe-101320	Prunus persica	43.12	4.00e-72	265.00
IUUC-Pva-102789	Pteropus vampyrus	69.97	2.00e-130	458.00
IUUC-Pgr-103479	Puccinia graminis	41.98	3.00e-70	258.00
IUUC-Ptt-103981	Puccinia triticina	42.81	2.00e-72	265.00
IUUC-Pte-104278	Pyrenophora teres	43.73	3.00e-76	278.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	43.73	3.00e-76	278.00
IUUC-Rno-105867	Rattus norvegicus	62.50	3.00e-108	384.00
IUUC-Sce-106251	Saccharomyces cerevisiae	39.88	2.00e-69	256.00
IUUC-Sha-107039	Sarcophilus harrisii	79.38	4.00e-158	550.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	45.05	2.00e-81	295.00
IUUC-Spo-108314	Schizosaccharomyces pombe	44.28	7.00e-79	286.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	44.79	5.00e-82	297.00
IUUC-Smo-108728	Selaginella moellendorffii	42.90	3.00e-73	268.00
IUUC-Sit-110801	Setaria italica	40.92	3.00e-71	261.00
IUUC-Sly-111326	Solanum lycopersicum	44.27	2.00e-74	272.00
IUUC-Stu-112458	Solanum tuberosum	43.73	5.00e-74	271.00
IUUC-Sbi-114063	Sorghum bicolor	40.31	4.00e-71	261.00
IUUC-Sre-115096	Sporisorium reilianum	43.28	1.00e-70	259.00
IUUC-Ssc-116080	Sus scrofa	79.26	2.00e-156	544.00
IUUC-Tgu-116988	Taeniopygia guttata	81.73	5.00e-162	563.00
IUUC-Tru-118766	Takifugu rubripes	85.14	3.00e-167	580.00
IUUC-Tni-120197	Tetraodon nigroviridis	85.14	1.00e-167	582.00
IUUC-Tca-121316	Theobroma cacao	40.92	3.00e-72	265.00
IUUC-Tre-122097	Trichoderma reesei	45.62	6.00e-81	293.00
IUUC-Tvi-122442	Trichoderma virens	45.62	2.00e-81	295.00
IUUC-Tae-125542	Triticum aestivum	41.95	2.00e-74	272.00
IUUC-Tur-126334	Triticum urartu	35.38	2.00e-54	206.00
IUUC-Tme-127038	Tuber melanosporum	46.25	1.00e-85	309.00
IUUC-Ttr-128659	Tursiops truncatus	73.07	3.00e-131	461.00
IUUC-Uma-129464	Ustilago maydis	43.28	4.00e-70	258.00
IUUC-Vda-129841	Verticillium dahliae	46.93	1.00e-81	296.00
IUUC-Vvi-131076	Vitis vinifera	42.60	2.00e-74	272.00
IUUC-Xtr-132395	Xenopus tropicalis	78.33	2.00e-156	545.00
IUUC-Xma-133383	Xiphophorus maculatus	84.52	9.00e-167	578.00
IUUC-Yli-134586	Yarrowia lipolytica	43.84	2.00e-67	249.00
IUUC-Zma-135904	Zea mays	41.59	7.00e-72	263.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence