iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108027

UUCD1 version

UUC-ScP-00270

Ensembl Protein ID

SPCC338.05c.1:pep

UniProt Accession

O74983; MMS2_SCHPO

Genbank Protein ID

AAL79845.1; CAA19336.1

Protein Name

Ubiquitin-conjugating enzyme spm2; Ubiquitin-conjugating enzyme variant MMS2 homolog

Genbank Nucleotide ID

AF470233; CU329672

Gene Name

mms2; spm2; SPCC338.05c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPCC338.05c	SPCC338.05c.1	SPCC338.05c.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-19	68.8	24	128
E2/UEV	3.60e-49	164.4	3	138

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UBC

   S: 15   egisakpvdesd..ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvC...lsilkeeekWspalsves 100
           +++s+++++ +d  l +w+++ilGp+++++e+++++l+i+++ +YP  PP v+f+++i  P v+ + Gkv    ++ l   ++W+  +s+e+
   Q: 24   SSCSYGLTNADDitLSDWNATILGPAHSVHENRIYSLKIHCDANYPDAPPIVTFVSRINLPGVDGEtGKVNphkIDCL---RHWKREYSMET 112
           5677777776666699************************************************988***73335555...6********** PP
   S: 101  vllsiqsllae.pnpe 115
           vll++++ +a+  n +
   Q: 113  VLLDLKKEMASsSNRK 128
           *******996514544 PP

E2/UEV

   S: 10   vvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigpertayegrIyqlklfvgkkYPekPPtvrfsskinmaevndsnGvvd 101
           +vprnf+lleele+gekglg+   sygl  +ddi+l  + +tI+gp ++++e+rIy+lk+ ++ +YP +PP+v+f+s+in+ +v  ++G+v+
   Q: 3    KVPRNFKLLEELEKGEKGLGESSCSYGLTNADDITLSDWNATILGPAHSVHENRIYSLKIHCDANYPDAPPIVTFVSRINLPGVDGETGKVN 94
           79****************************************************************************************** PP
   S: 102  pralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           p+++ +L++Wkreys+e+vl +lkke++s+ nrkl+qPpeG++f
   Q: 95   PHKIDCLRHWKREYSMETVLLDLKKEMASSSNRKLPQPPEGSTF 138
           *****************************************976 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Has a role in the DNA error-free postreplication repair (PRR) pathway. Lacks catalytic activity by itself. The ubc13/spm2 heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.

Protein Sequence
(Fasta)

MAKVPRNFKL LEELEKGEKG LGESSCSYGL TNADDITLSD WNATILGPAH SVHENRIYSL 60
KIHCDANYPD APPIVTFVSR INLPGVDGET GKVNPHKIDC LRHWKREYSM ETVLLDLKKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGAAATTG CAGCCTGTGA CAGGTTCACT AAACCAGTAT TGAATATTCT ATAAAGTAAT 60
TGTTGAAATA TACTTTGACA GATTGCTAGC CTTGGTTCGA ATGTTTTCGA GACCCAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination

KEGG

spo:SPCC338.05c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000910	Aegilops tauschii	57.66	8.00e-43	163.00
IUUC-Aml-001242	Ailuropoda melanoleuca	51.09	8.00e-38	149.00
IUUC-Atr-003059	Amborella trichopoda	57.89	2.00e-43	166.00
IUUC-Apl-003600	Anas platyrhynchos	51.09	5.00e-39	151.00
IUUC-Aca-005104	Anolis carolinensis	51.09	3.00e-41	158.00
IUUC-Aly-006035	Arabidopsis lyrata	57.35	2.00e-41	159.00
IUUC-Ath-007596	Arabidopsis thaliana	55.88	6.00e-40	154.00
IUUC-Ago-007810	Ashbya gossypii	68.12	5.00e-47	177.00
IUUC-Acl-008375	Aspergillus clavatus	62.86	4.00e-45	171.00
IUUC-Afl-008598	Aspergillus flavus	63.50	4.00e-45	171.00
IUUC-Afu-008838	Aspergillus fumigatus	63.50	4.00e-46	174.00
IUUC-Ani-009325	Aspergillus nidulans	65.69	1.00e-46	176.00
IUUC-Ang-009631	Aspergillus niger	66.42	5.00e-47	177.00
IUUC-Aor-010051	Aspergillus oryzae	63.50	4.00e-45	171.00
IUUC-Ate-010471	Aspergillus terreus	62.04	7.00e-40	153.00
IUUC-Ame-010710	Astyanax mexicanus	46.72	7.00e-39	150.00
IUUC-Bgr-012010	Blumeria graminis	57.66	7.00e-39	150.00
IUUC-Bta-013403	Bos taurus	51.09	4.00e-39	151.00
IUUC-Bci-013649	Botrytis cinerea	65.22	2.00e-44	169.00
IUUC-Bdi-014826	Brachypodium distachyon	58.52	8.00e-43	163.00
IUUC-Bol-016517	Brassica oleracea	57.78	9.00e-43	163.00
IUUC-Bra-018041	Brassica rapa	57.78	6.00e-43	164.00
IUUC-Cel-018398	Caenorhabditis elegans	44.60	2.00e-31	125.00
IUUC-Cja-019316	Callithrix jacchus	51.09	4.00e-39	151.00
IUUC-Cfa-021118	Canis familiaris	51.09	5.00e-39	151.00
IUUC-Cpo-021317	Cavia porcellus	49.64	1.00e-40	156.00
IUUC-Cre-022629	Chlamydomonas reinhardtii	51.85	3.00e-43	164.00
IUUC-Csa-024275	Chlorocebus sabaeus	51.09	1.00e-37	148.00
IUUC-Cho-025024	Choloepus hoffmanni	48.84	2.00e-23	97.80
IUUC-Cin-025219	Ciona intestinalis	44.12	2.00e-20	89.00
IUUC-Cgl-026596	Colletotrichum gloeosporioides	63.50	1.00e-44	169.00
IUUC-Cne-026817	Cryptococcus neoformans	57.25	2.00e-45	172.00
IUUC-Cme-027257	Cyanidioschyzon merolae	55.47	9.00e-30	120.00
IUUC-Dre-028062	Danio rerio	48.91	2.00e-40	155.00
IUUC-Dno-029762	Dasypus novemcinctus	51.09	5.00e-39	150.00
IUUC-Dse-031272	Dothistroma septosporum	63.50	6.00e-44	167.00
IUUC-Dme-031635	Drosophila melanogaster	45.93	7.00e-37	144.00
IUUC-Ete-033017	Echinops telfairi	48.91	3.00e-35	140.00
IUUC-Eca-034422	Equus caballus	51.09	5.00e-39	150.00
IUUC-Eeu-035327	Erinaceus europaeus	51.09	7.00e-38	149.00
IUUC-Fca-035746	Felis catus	49.64	1.00e-40	156.00
IUUC-Fal-037350	Ficedula albicollis	51.09	4.00e-39	151.00
IUUC-Fox-037803	Fusarium oxysporum	63.04	5.00e-44	167.00
IUUC-Fso-038147	Fusarium solani	63.50	3.00e-44	168.00
IUUC-Gmo-039237	Gadus morhua	47.83	5.00e-40	154.00
IUUC-Ggr-039839	Gaeumannomyces graminis	50.66	9.00e-32	127.00
IUUC-Gga-040746	Gallus gallus	51.09	1.00e-39	153.00
IUUC-Gac-041936	Gasterosteus aculeatus	48.91	6.00e-32	127.00
IUUC-Gma-043818	Glycine max	57.78	1.00e-41	159.00
IUUC-Ggo-044696	Gorilla gorilla	49.64	8.00e-41	157.00
IUUC-Hsa-045659	Homo sapiens	51.09	4.00e-39	151.00
IUUC-Hvu-047307	Hordeum vulgare	58.52	9.00e-44	166.00
IUUC-Itr-048139	Ictidomys tridecemlineatus	51.09	5.00e-39	150.00
IUUC-Kpa-049337	Komagataella pastoris	63.31	8.00e-41	157.00
IUUC-Lch-050494	Latimeria chalumnae	45.99	2.00e-37	145.00
IUUC-Lpe-050874	Leersia perrieri	59.70	7.00e-43	164.00
IUUC-Loc-052012	Lepisosteus oculatus	48.91	1.00e-40	156.00
IUUC-Lma-053194	Leptosphaeria maculans	65.69	5.00e-46	174.00
IUUC-Laf-054176	Loxodonta africana	51.09	4.00e-39	151.00
IUUC-Mcc-055788	Macaca mulatta	51.09	1.00e-37	148.00
IUUC-Meu-056842	Macropus eugenii	43.18	1.00e-16	79.00
IUUC-Mor-056915	Magnaporthe oryzae	35.95	8.00e-21	90.90
IUUC-Mpo-057437	Magnaporthe poae	50.66	1.00e-31	127.00
IUUC-Mtr-058577	Medicago truncatula	57.66	1.00e-40	156.00
IUUC-Mla-058919	Melampsora laricipopulina	57.66	2.00e-38	149.00
IUUC-Mga-059951	Meleagris gallopavo	50.36	1.00e-38	149.00
IUUC-Mvi-060260	Microbotryum violaceum	63.04	4.00e-46	174.00
IUUC-Mmr-061751	Microcebus murinus	49.64	8.00e-41	157.00
IUUC-Mdo-062503	Monodelphis domestica	49.64	1.00e-36	143.00
IUUC-Mmu-063294	Mus musculus	48.91	5.00e-41	157.00
IUUC-Mac-065394	Musa acuminata	59.26	3.00e-42	161.00
IUUC-Mpu-065775	Mustela putorius furo	51.09	4.00e-39	151.00
IUUC-Mlu-067269	Myotis lucifugus	49.31	9.00e-38	147.00
IUUC-Nfi-068400	Neosartorya fischeri	58.76	2.00e-36	141.00
IUUC-Ncr-068946	Neurospora crassa	50.00	7.00e-41	157.00
IUUC-Nle-069245	Nomascus leucogenys	51.09	4.00e-39	151.00
IUUC-Opr-070697	Ochotona princeps	43.07	1.00e-31	126.00
IUUC-Ont-071359	Oreochromis niloticus	48.91	4.00e-40	154.00
IUUC-Oan-073215	Ornithorhynchus anatinus	47.48	2.00e-34	135.00
IUUC-Ocu-074447	Oryctolagus cuniculus	49.64	3.00e-38	148.00
IUUC-Oba-075005	Oryza barthii	58.96	2.00e-42	162.00
IUUC-Obr-076238	Oryza brachyantha	58.21	2.00e-42	162.00
IUUC-Ogl-077233	Oryza glaberrima	58.96	2.00e-42	162.00
IUUC-Ogu-078374	Oryza glumaepatula	58.96	2.00e-42	162.00
IUUC-Oin-079721	Oryza indica	58.96	2.00e-42	162.00
IUUC-Olo-080242	Oryza longistaminata	57.58	3.00e-43	165.00
IUUC-Ome-081761	Oryza meridionalis	60.00	2.00e-42	163.00
IUUC-Oni-082346	Oryza nivara	58.96	2.00e-42	162.00
IUUC-Opu-083148	Oryza punctata	58.96	2.00e-42	162.00
IUUC-Oru-084359	Oryza rufipogon	58.96	2.00e-42	162.00
IUUC-Osa-085664	Oryza sativa	58.96	2.00e-42	162.00
IUUC-Ola-087529	Oryzias latipes	48.91	8.00e-32	127.00
IUUC-Olu-087815	Ostreococcus lucimarinus	38.05	3.00e-18	82.40
IUUC-Oga-087972	Otolemur garnettii	51.09	5.00e-39	150.00
IUUC-Oar-090166	Ovis aries	51.09	7.00e-38	149.00
IUUC-Ptr-090866	Pan troglodytes	51.09	4.00e-39	151.00
IUUC-Pan-091955	Papio anubis	49.64	8.00e-41	157.00
IUUC-Psi-093138	Pelodiscus sinensis	49.64	2.00e-36	142.00
IUUC-Pno-095070	Phaeosphaeria nodorum	64.96	7.00e-46	173.00
IUUC-Ppa-095557	Physcomitrella patens	59.26	7.00e-45	170.00
IUUC-Pfo-097209	Poecilia formosa	49.64	1.00e-35	140.00
IUUC-Pab-098403	Pongo abelii	51.09	6.00e-38	149.00
IUUC-Pop-099786	Populus trichocarpa	57.78	3.00e-41	158.00
IUUC-Pca-100723	Procavia capensis	51.09	8.00e-38	149.00
IUUC-Ppe-101196	Prunus persica	58.52	2.00e-41	159.00
IUUC-Pva-102989	Pteropus vampyrus	49.64	8.00e-41	157.00
IUUC-Pgr-103617	Puccinia graminis	59.12	1.00e-38	149.00
IUUC-Ptt-104008	Puccinia triticina	50.70	1.00e-18	83.60
IUUC-Pte-104176	Pyrenophora teres	64.96	4.00e-45	171.00
IUUC-Pyt-104517	Pyrenophora triticirepentis	64.96	4.00e-45	171.00
IUUC-Rno-105839	Rattus norvegicus	49.64	3.00e-41	158.00
IUUC-Sce-106349	Saccharomyces cerevisiae	66.67	3.00e-44	168.00
IUUC-Sha-107363	Sarcophilus harrisii	51.09	4.00e-39	151.00
IUUC-Sja-107722	Schizosaccharomyces japonicus	77.54	7.00e-55	203.00
IUUC-Ssl-108493	Sclerotinia sclerotiorum	65.69	2.00e-44	169.00
IUUC-Smo-109006	Selaginella moellendorffii	56.83	1.00e-35	139.00
IUUC-Sit-110302	Setaria italica	59.26	5.00e-43	164.00
IUUC-Sly-111205	Solanum lycopersicum	58.52	7.00e-42	160.00
IUUC-Stu-112459	Solanum tuberosum	58.52	6.00e-42	160.00
IUUC-Sar-113197	Sorex araneus	54.44	8.00e-28	115.00
IUUC-Sbi-114210	Sorghum bicolor	60.00	1.00e-42	163.00
IUUC-Sre-114909	Sporisorium reilianum	57.97	5.00e-40	154.00
IUUC-Ssc-115939	Sus scrofa	51.09	4.00e-39	151.00
IUUC-Tgu-117289	Taeniopygia guttata	51.09	3.00e-38	149.00
IUUC-Tru-118526	Takifugu rubripes	46.72	2.00e-25	105.00
IUUC-Tsy-119103	Tarsius syrichta	54.44	7.00e-28	114.00
IUUC-Tni-120169	Tetraodon nigroviridis	48.18	3.00e-27	112.00
IUUC-Tca-121288	Theobroma cacao	57.78	1.00e-41	159.00
IUUC-Tre-121971	Trichoderma reesei	62.77	3.00e-44	168.00
IUUC-Tvi-122622	Trichoderma virens	62.04	4.00e-43	164.00
IUUC-Tae-123818	Triticum aestivum	58.52	9.00e-44	166.00
IUUC-Tur-126083	Triticum urartu	58.52	1.00e-43	166.00
IUUC-Tme-127171	Tuber melanosporum	63.77	8.00e-43	163.00
IUUC-Tbe-128105	Tupaia belangeri	47.45	2.00e-38	150.00
IUUC-Ttr-128790	Tursiops truncatus	51.09	7.00e-38	149.00
IUUC-Uma-129419	Ustilago maydis	59.42	8.00e-41	156.00
IUUC-Vda-129776	Verticillium dahliae	62.59	1.00e-43	166.00
IUUC-Vpa-130575	Vicugna pacos	50.36	3.00e-37	146.00
IUUC-Vvi-131466	Vitis vinifera	57.78	8.00e-42	160.00
IUUC-Xtr-132359	Xenopus tropicalis	48.18	3.00e-37	145.00
IUUC-Xma-134032	Xiphophorus maculatus	49.64	1.00e-35	140.00
IUUC-Yli-134591	Yarrowia lipolytica	58.42	1.00e-34	135.00
IUUC-Zma-135558	Zea mays	58.21	2.00e-42	162.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence