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Tag Content
UUCD2 ID IUUC-Pab-098269
UUCD1 version UUC-PoA-00589
Ensembl Protein ID ENSPPYP00000015770.2
UniProt Accession H2PBE9; H2PBE9_PONAB
Genbank Protein ID ENSPPYP00000015770
Protein Name Phosphoinositide 3-kinase regulatory subunit 4
Genbank Nucleotide ID ABGA01292924
Gene Name PIK3R4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000014096.2 ENSPPYT00000016392.2 ENSPPYP00000015770.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.00e-15 57.3 992 1021
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v+ ++  ++  l++++s+Dgt+k+W+
   Q: 992  HKSAVNRIRVsDEhSLFATCSNDGTVKIWN 1021
           9999999999544788*************9 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MGNQLAGIAP SQILSVESYF SDIHDFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
TLPLTSYKQE LEELKIRLNS AQNCLPFQKA SEKASEKAAM LFRQYVRDNL YDRISTRPFL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098269|E3,WD_repeat|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGAAATC AGCTTGCTGG CATTGCTCCC TCCCAGATCC TTTCTGTAGA GAGTTATTTT 60
TCAGATATTC ATGACTTTGA ATATGATAAA AGCCTGGGGA GTACTCGGTT TTTTAAAGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098269|E3,WD_repeat|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00069--Pkinase
PF00400--WD40
SMART

SM00220--S_TKc
SM00320--WD40
Gene Ontology

GO:0005930--C:axoneme
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0035032--C:phosphatidylinositol 3-kinase complex, class III
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000213 Aegilops tauschii 32.71 7.00e-43 169.00
IUUC-Aml-001659 Ailuropoda melanoleuca 96.98 0.00e+00 2663.00
IUUC-Atr-002968 Amborella trichopoda 40.06 1.00e-47 186.00
IUUC-Apl-003418 Anas platyrhynchos 90.76 0.00e+00 2559.00
IUUC-Aca-004344 Anolis carolinensis 89.75 0.00e+00 2266.00
IUUC-Aly-006107 Arabidopsis lyrata 46.67 4.00e-71 263.00
IUUC-Ath-007260 Arabidopsis thaliana 46.97 8.00e-72 266.00
IUUC-Ago-007721 Ashbya gossypii 24.89 4.00e-57 217.00
IUUC-Acl-008378 Aspergillus clavatus 36.95 5.00e-148 519.00
IUUC-Afl-008632 Aspergillus flavus 35.75 5.00e-140 493.00
IUUC-Afu-009020 Aspergillus fumigatus 36.45 2.00e-141 497.00
IUUC-Ani-009204 Aspergillus nidulans 35.29 3.00e-130 460.00
IUUC-Ang-009811 Aspergillus niger 34.96 1.00e-137 484.00
IUUC-Aor-010168 Aspergillus oryzae 35.75 5.00e-140 493.00
IUUC-Ate-010556 Aspergillus terreus 35.33 2.00e-139 490.00
IUUC-Ame-011955 Astyanax mexicanus 80.57 0.00e+00 1815.00
IUUC-Bgr-012050 Blumeria graminis 36.46 1.00e-138 488.00
IUUC-Bta-012432 Bos taurus 95.80 0.00e+00 2678.00
IUUC-Bci-013846 Botrytis cinerea 34.35 2.00e-140 494.00
IUUC-Bdi-015072 Brachypodium distachyon 42.98 1.00e-66 248.00
IUUC-Bol-015314 Brassica oleracea 46.97 7.00e-72 266.00
IUUC-Bra-017476 Brassica rapa 46.97 9.00e-72 265.00
IUUC-Cel-018550 Caenorhabditis elegans 31.73 3.00e-84 307.00
IUUC-Cja-019538 Callithrix jacchus 97.79 0.00e+00 2722.00
IUUC-Cfa-020483 Canis familiaris 96.83 0.00e+00 2672.00
IUUC-Cpo-021392 Cavia porcellus 96.47 0.00e+00 2679.00
IUUC-Csa-024112 Chlorocebus sabaeus 98.67 0.00e+00 2742.00
IUUC-Cho-025015 Choloepus hoffmanni 89.96 0.00e+00 926.00
IUUC-Cin-025209 Ciona intestinalis 41.02 0.00e+00 1062.00
IUUC-Csv-026334 Ciona savignyi 41.86 0.00e+00 891.00
IUUC-Cgl-026447 Colletotrichum gloeosporioides 35.80 2.00e-142 501.00
IUUC-Cne-026999 Cryptococcus neoformans 39.12 1.00e-115 411.00
IUUC-Dre-028662 Danio rerio 80.93 0.00e+00 2283.00
IUUC-Dno-029545 Dasypus novemcinctus 94.70 0.00e+00 2619.00
IUUC-Dor-030941 Dipodomys ordii 64.89 0.00e+00 694.00
IUUC-Dse-031455 Dothistroma septosporum 36.42 5.00e-135 476.00
IUUC-Dme-031726 Drosophila melanogaster 40.30 0.00e+00 981.00
IUUC-Ete-033147 Echinops telfairi 94.69 0.00e+00 1016.00
IUUC-Eca-034025 Equus caballus 97.20 0.00e+00 2700.00
IUUC-Eeu-034480 Erinaceus europaeus 90.05 0.00e+00 1501.00
IUUC-Fca-035741 Felis catus 96.39 0.00e+00 2660.00
IUUC-Fal-037666 Ficedula albicollis 89.73 0.00e+00 2534.00
IUUC-Fox-037818 Fusarium oxysporum 33.79 1.00e-124 441.00
IUUC-Fso-038086 Fusarium solani 34.04 1.00e-127 451.00
IUUC-Gmo-038804 Gadus morhua 78.82 0.00e+00 717.00
IUUC-Ggr-039800 Gaeumannomyces graminis 35.49 4.00e-132 466.00
IUUC-Gga-041251 Gallus gallus 89.16 0.00e+00 1981.00
IUUC-Gac-042376 Gasterosteus aculeatus 78.51 0.00e+00 2216.00
IUUC-Gma-044095 Glycine max 45.86 1.00e-73 272.00
IUUC-Ggo-044506 Gorilla gorilla 98.16 0.00e+00 2724.00
IUUC-Hsa-045871 Homo sapiens 98.90 0.00e+00 2744.00
IUUC-Hvu-047648 Hordeum vulgare 31.76 1.00e-44 175.00
IUUC-Itr-048082 Ictidomys tridecemlineatus 98.67 0.00e+00 1189.00
IUUC-Kpa-049390 Komagataella pastoris 32.53 3.00e-126 446.00
IUUC-Lch-050284 Latimeria chalumnae 85.00 0.00e+00 2313.00
IUUC-Lpe-050880 Leersia perrieri 41.76 3.00e-64 241.00
IUUC-Loc-052815 Lepisosteus oculatus 81.40 0.00e+00 2284.00
IUUC-Lma-053324 Leptosphaeria maculans 36.38 4.00e-144 506.00
IUUC-Laf-054204 Loxodonta africana 85.30 0.00e+00 2281.00
IUUC-Mcc-054612 Macaca mulatta 98.60 0.00e+00 2734.00
IUUC-Meu-056227 Macropus eugenii 85.52 0.00e+00 849.00
IUUC-Mor-057094 Magnaporthe oryzae 36.17 3.00e-132 466.00
IUUC-Mtr-058550 Medicago truncatula 43.92 7.00e-73 269.00
IUUC-Mla-058893 Melampsora laricipopulina 35.01 5.00e-129 456.00
IUUC-Mga-059474 Meleagris gallopavo 89.60 0.00e+00 2400.00
IUUC-Mvi-060227 Microbotryum violaceum 45.01 5.00e-85 310.00
IUUC-Mmr-061543 Microcebus murinus 89.98 0.00e+00 2413.00
IUUC-Mdo-062129 Monodelphis domestica 92.84 0.00e+00 2517.00
IUUC-Mmu-064381 Mus musculus 95.07 0.00e+00 2652.00
IUUC-Mac-064455 Musa acuminata 38.36 8.00e-123 435.00
IUUC-Mpu-066151 Mustela putorius furo 98.14 0.00e+00 981.00
IUUC-Mlu-067824 Myotis lucifugus 97.13 0.00e+00 2691.00
IUUC-Nfi-068241 Neosartorya fischeri 37.29 1.00e-144 508.00
IUUC-Ncr-068964 Neurospora crassa 35.97 1.00e-138 488.00
IUUC-Nle-069152 Nomascus leucogenys 98.75 0.00e+00 2738.00
IUUC-Opr-070870 Ochotona princeps 85.19 0.00e+00 1427.00
IUUC-Ont-071293 Oreochromis niloticus 79.78 0.00e+00 2256.00
IUUC-Oan-072852 Ornithorhynchus anatinus 87.25 0.00e+00 2404.00
IUUC-Ocu-074727 Oryctolagus cuniculus 96.98 0.00e+00 2661.00
IUUC-Oba-075932 Oryza barthii 39.69 5.00e-64 240.00
IUUC-Obr-076424 Oryza brachyantha 49.05 4.00e-61 230.00
IUUC-Ogl-077491 Oryza glaberrima 39.69 5.00e-64 240.00
IUUC-Ogu-078933 Oryza glumaepatula 45.51 2.00e-67 251.00
IUUC-Oin-079604 Oryza indica 44.13 1.00e-69 258.00
IUUC-Olo-080850 Oryza longistaminata 35.48 8.00e-115 408.00
IUUC-Ome-081860 Oryza meridionalis 44.13 1.00e-69 258.00
IUUC-Oni-082895 Oryza nivara 39.69 9.00e-64 239.00
IUUC-Opu-083741 Oryza punctata 43.84 4.00e-68 253.00
IUUC-Oru-084616 Oryza rufipogon 39.39 2.00e-63 238.00
IUUC-Osa-085941 Oryza sativa 27.80 3.00e-35 142.00
IUUC-Ola-087357 Oryzias latipes 86.22 7.00e-160 555.00
IUUC-Olu-087659 Ostreococcus lucimarinus 30.32 1.00e-88 321.00
IUUC-Oga-088555 Otolemur garnettii 97.35 0.00e+00 2679.00
IUUC-Oar-089304 Ovis aries 95.88 0.00e+00 1305.00
IUUC-Ptr-091140 Pan troglodytes 98.82 0.00e+00 2742.00
IUUC-Pan-092413 Papio anubis 98.25 0.00e+00 2623.00
IUUC-Psi-093210 Pelodiscus sinensis 90.60 0.00e+00 2556.00
IUUC-Pma-094674 Petromyzon marinus 55.34 0.00e+00 710.00
IUUC-Pno-094969 Phaeosphaeria nodorum 31.17 2.00e-144 507.00
IUUC-Ppa-096017 Physcomitrella patens 46.42 5.00e-77 283.00
IUUC-Pfo-096077 Poecilia formosa 79.68 0.00e+00 2216.00
IUUC-Pop-100052 Populus trichocarpa 44.51 2.00e-64 241.00
IUUC-Pca-100377 Procavia capensis 91.25 0.00e+00 2420.00
IUUC-Ppe-101445 Prunus persica 46.69 4.00e-73 270.00
IUUC-Pva-102198 Pteropus vampyrus 97.91 0.00e+00 1783.00
IUUC-Pgr-103544 Puccinia graminis 47.80 1.00e-81 299.00
IUUC-Ptt-103964 Puccinia triticina 47.48 1.00e-78 288.00
IUUC-Pte-104196 Pyrenophora teres 36.82 6.00e-137 482.00
IUUC-Pyt-104544 Pyrenophora triticirepentis 36.91 1.00e-135 478.00
IUUC-Rno-105256 Rattus norvegicus 94.92 0.00e+00 2650.00
IUUC-Sce-106295 Saccharomyces cerevisiae 40.71 1.00e-69 259.00
IUUC-Sha-107597 Sarcophilus harrisii 91.93 0.00e+00 2547.00
IUUC-Sja-107781 Schizosaccharomyces japonicus 42.77 3.00e-73 271.00
IUUC-Spo-108031 Schizosaccharomyces pombe 44.14 4.00e-73 270.00
IUUC-Ssl-108579 Sclerotinia sclerotiorum 35.64 2.00e-135 477.00
IUUC-Smo-108679 Selaginella moellendorffii 44.29 3.00e-79 290.00
IUUC-Sit-110765 Setaria italica 41.55 7.00e-64 239.00
IUUC-Sly-111527 Solanum lycopersicum 44.20 2.00e-73 271.00
IUUC-Stu-112899 Solanum tuberosum 44.20 9.00e-74 272.00
IUUC-Sar-112986 Sorex araneus 95.95 0.00e+00 2669.00
IUUC-Sbi-114604 Sorghum bicolor 42.69 4.00e-66 247.00
IUUC-Sre-115191 Sporisorium reilianum 44.00 6.00e-67 250.00
IUUC-Ssc-115440 Sus scrofa 95.14 0.00e+00 2641.00
IUUC-Tgu-116633 Taeniopygia guttata 89.88 0.00e+00 2535.00
IUUC-Tru-118439 Takifugu rubripes 78.00 0.00e+00 2219.00
IUUC-Tsy-119472 Tarsius syrichta 90.09 0.00e+00 1420.00
IUUC-Tni-119808 Tetraodon nigroviridis 74.36 0.00e+00 2032.00
IUUC-Tca-121648 Theobroma cacao 47.59 1.00e-74 275.00
IUUC-Tre-122161 Trichoderma reesei 34.13 3.00e-120 427.00
IUUC-Tvi-122575 Trichoderma virens 33.15 2.00e-111 397.00
IUUC-Tae-123381 Triticum aestivum 46.62 7.00e-67 249.00
IUUC-Tur-126291 Triticum urartu 44.13 1.00e-67 251.00
IUUC-Tme-126979 Tuber melanosporum 37.59 4.00e-151 529.00
IUUC-Tbe-127576 Tupaia belangeri 80.70 0.00e+00 917.00
IUUC-Ttr-129106 Tursiops truncatus 98.03 0.00e+00 1296.00
IUUC-Uma-129633 Ustilago maydis 43.17 1.00e-75 279.00
IUUC-Vda-130001 Verticillium dahliae 34.49 7.00e-128 452.00
IUUC-Vpa-130733 Vicugna pacos 89.07 0.00e+00 1294.00
IUUC-Vvi-131318 Vitis vinifera 44.60 3.00e-71 264.00
IUUC-Xtr-131908 Xenopus tropicalis 85.58 0.00e+00 2425.00
IUUC-Xma-133331 Xiphophorus maculatus 79.53 0.00e+00 2229.00
IUUC-Yli-134651 Yarrowia lipolytica 37.07 1.00e-120 428.00
IUUC-Zma-135850 Zea mays 41.10 3.00e-67 251.00
Created Date 25-Jun-2017

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