iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Vvi-130997

UUCD1 version

UUC-ViV-00696

Ensembl Protein ID

VIT_11s0016g04180.t01

UniProt Accession

F6HH36; F6HH36_VITVI

Genbank Protein ID

CCB51532.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

FN595756

Gene Name

VIT_11s0016g04180

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VIT_11s0016g04180	VIT_11s0016g04180.t01	VIT_11s0016g04180.t01

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-32	110.7	184	224
UBD/Beta-Prp	1.10e-65	222.4	14	292

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H  +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 184  HMKGVNCVDYftgGDkPYLITGSDDQTAKVWDYQTKSCVQT 224
           8889****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           +++++++v+ +p +++++++ ++gt+ ++d+ ++++++s++  + +v++ kf+ ++++ v g++D++i+v++++t + v ++++h d+
   Q: 14   RSERVKSVDLHPTEPWILASLYSGTVCIYDYLSQTMIKSFEVTDLPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKVTIFEAHADY 101
           5678999********************************************************************************* PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           +++++++p+  +++s s+d  i++wd+++g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h + v
   Q: 102  IRCVAVHPTLPYVLSSSDDLLIKLWDWDKGWTCTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDD-HMKGV 188
           *******************************9999*********************************************98.***** PP
   S: 184  ysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           ++++     ++++l++gs+d+t k+wd+qt++cv+tl+ght nv+sv f+p+  ++ +gs+Dg++riW  ++  l +tl++  ++v++
   Q: 189  NCVDyfTGGDKPYLITGSDDQTAKVWDYQTKSCVQTLEGHTHNVSSVCFHPELPIIFTGSEDGTVRIWHATTYRLENTLNYGLERVWA 276
           ****6444555***************************************************************************** PP
   S: 270  vavlsfgdnvlvlgse 285
             +++ +++v++ ++e
   Q: 277  LGCMRGSRRVVIGFDE 292
           ***8888888887766 PP

Organism

Vitis vinifera

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK LAQRSERVKS VDLHPTEPWI LASLYSGTVC IYDYLSQTMI KSFEVTDLPV 60
RSAKFIARKQ WVVAGADDMF IRVYNYNTMD KVTIFEAHAD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGTCTTCTT TCTTCGCATC AACTTCATCA ATCAAGAACC GTAGTTTCTC TCACCTGTAA 60
AAATGGTAAC GGTTACTTTT TTCTTCTCTT TTGAGTGATT AGATCTGGTT TTAGGTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

vvi:100247411

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence