iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007631

Ensembl Protein ID

AT4G22140.3

UniProt Accession

F4JL28; O65462; Q56W44; Q8H1R5; EBS_ARATH

Genbank Protein ID

CAA18117.1; CAB79169.1; AEE84562.1; AEE84563.1; ANM67164.1; BAD95354.1; AAN13058.1

Protein Name

Chromatin remodeling protein EBS; Protein EARLY BOLTING IN SHORT DAYS

Genbank Nucleotide ID

AL022140; AL161556; CP002687; CP002687; CP002687; AK222203; AY142507

Gene Name

EBS; At4g22140; F1N20.240

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G22140	AT4G22140.3	AT4G22140.3
AT4G22140	AT4G22140.2	AT4G22140.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.20e-09	36.6	148	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           +C  C+ +++ ++ +v+Ce C++w+HpaC+++++ee ++ ++ + C +C+s
   Q: 148  YC-KCEMPYNPDDLMVQCEGCKDWYHPACVGMTIEEAKKLDH-FVCAECSS 196
           78.7*****************************888888887.******86 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Chromatin remodeling factor that binds to methylated histone (e.g. H3K4me2/3) to prevent their acetylation (e.g. H3K9K14Ac), likely by recruiting histone deacetylase (HDAC) complexes, and thus regulate the transcription of target genes (PubMed:25281686). Negative regulator in developmental processes in a gibberellic acid- (GA-) dependent manner, such as germination, flowering induction, and flower organ specification, probably by modulating developmental gene expression (PubMed:11340178, PubMed:25281686). Involved in the chromatin-mediated repression of floral initiation and controls genes regulating flowering (PubMed:25281686). Negatively regulates the expression of the floral integrator FT epigenetically, by preventing high levels of H3 acetylation, thus maintaining an inactive chromatin conformation at FT locus (PubMed:25281686, PubMed:12837946).

Protein Sequence
(Fasta)

MAKTRPGVAS KIKTGRKELD SYTIKGTNKV VRAGDCVLMR PSDAGKPPYV ARVEKIEADA 60
RNNVKVHCRW YYRPEESLGG RRQFHGAKEL FLSDHFDVQS AHTIEGKCIV HTFKNYTRLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAAATGA ATTGGGCTTT GTGAACAGTA AAACTCCCAA ATTTGCAAAT GACTCATCTT 60
CTTCACCTGG AGAGAATCTA GGGTTCCAGA TTTACTCTTC GTCTTCCTCT CTTCGCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0287--Flowering
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001025--BAH_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51038--BAH
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01426--BAH
PF00628--PHD

SMART

SM00439--BAH
SM00249--PHD

Gene Ontology

GO:0000785--C:chromatin
GO:0005677--C:chromatin silencing complex
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0035064--F:methylated histone binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0006325--P:chromatin organization
GO:0006342--P:chromatin silencing
GO:0016569--P:covalent chromatin modification
GO:0009908--P:flower development
GO:0031507--P:heterochromatin assembly
GO:0035067--P:negative regulation of histone acetylation
GO:0048579--P:negative regulation of long-day photoperiodism, flowering
GO:0009791--P:post-embryonic development
GO:2000028--P:regulation of photoperiodism, flowering
GO:0006355--P:regulation of transcription, DNA-templated
GO:0009845--P:seed germination
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT4G22140

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002986	Amborella trichopoda	79.72	1.00e-105	374.00
IUUC-Aly-005717	Arabidopsis lyrata	97.86	5.00e-138	482.00
IUUC-Ate-010345	Aspergillus terreus	39.47	4.00e-04	40.40
IUUC-Bgr-012210	Blumeria graminis	49.09	6.00e-09	55.10
IUUC-Bdi-014153	Brachypodium distachyon	74.61	1.00e-91	327.00
IUUC-Bol-015174	Brassica oleracea	97.70	7.00e-128	448.00
IUUC-Bra-018028	Brassica rapa	96.36	4.00e-128	449.00
IUUC-Cre-022934	Chlamydomonas reinhardtii	45.18	8.00e-45	172.00
IUUC-Cne-026894	Cryptococcus neoformans	41.54	7.00e-09	55.10
IUUC-Fal-037017	Ficedula albicollis	46.00	1.00e-10	61.60
IUUC-Fso-038446	Fusarium solani	38.89	4.00e-06	45.10
IUUC-Gma-043039	Glycine max	84.79	3.00e-110	390.00
IUUC-Hvu-047723	Hordeum vulgare	59.28	5.00e-75	273.00
IUUC-Lpe-051400	Leersia perrieri	74.52	2.00e-94	337.00
IUUC-Lma-053190	Leptosphaeria maculans	35.09	9.00e-05	42.70
IUUC-Mtr-057710	Medicago truncatula	84.33	3.00e-105	373.00
IUUC-Mla-058837	Melampsora laricipopulina	41.67	3.00e-06	46.20
IUUC-Mmr-061132	Microcebus murinus	46.00	1.00e-10	61.60
IUUC-Mmu-063458	Mus musculus	46.00	1.00e-10	62.00
IUUC-Mac-064749	Musa acuminata	77.42	2.00e-99	354.00
IUUC-Oba-075188	Oryza barthii	72.14	7.00e-92	328.00
IUUC-Obr-076844	Oryza brachyantha	72.64	2.00e-92	330.00
IUUC-Ogl-077260	Oryza glaberrima	72.14	7.00e-92	328.00
IUUC-Ogu-078663	Oryza glumaepatula	76.68	2.00e-93	333.00
IUUC-Oin-079894	Oryza indica	76.17	3.00e-93	333.00
IUUC-Olo-080411	Oryza longistaminata	76.17	4.00e-93	333.00
IUUC-Ome-081623	Oryza meridionalis	76.17	2.00e-92	330.00
IUUC-Oni-082587	Oryza nivara	76.17	3.00e-93	333.00
IUUC-Opu-083591	Oryza punctata	74.52	2.00e-97	347.00
IUUC-Oru-084597	Oryza rufipogon	75.65	2.00e-92	330.00
IUUC-Osa-086057	Oryza sativa	76.17	3.00e-93	333.00
IUUC-Pan-092346	Papio anubis	40.00	3.00e-11	63.50
IUUC-Pno-094853	Phaeosphaeria nodorum	36.73	1.00e-05	44.70
IUUC-Ppa-095639	Physcomitrella patens	73.87	6.00e-79	286.00
IUUC-Pop-098948	Populus trichocarpa	84.86	6.00e-113	399.00
IUUC-Ppe-101639	Prunus persica	80.18	2.00e-107	380.00
IUUC-Pgr-103292	Puccinia graminis	33.96	1.00e-05	43.50
IUUC-Ptt-103983	Puccinia triticina	35.85	2.00e-06	45.80
IUUC-Pte-104158	Pyrenophora teres	38.78	4.00e-05	42.70
IUUC-Pyt-104466	Pyrenophora triticirepentis	36.54	3.00e-05	42.70
IUUC-Rno-105402	Rattus norvegicus	44.00	5.00e-10	59.70
IUUC-Spo-108246	Schizosaccharomyces pombe	33.96	4.00e-07	50.80
IUUC-Smo-109649	Selaginella moellendorffii	71.28	8.00e-87	311.00
IUUC-Sit-110411	Setaria italica	73.56	3.00e-97	346.00
IUUC-Sly-111450	Solanum lycopersicum	76.96	1.00e-102	364.00
IUUC-Stu-112123	Solanum tuberosum	76.55	1.00e-106	377.00
IUUC-Sbi-114186	Sorghum bicolor	71.63	1.00e-94	338.00
IUUC-Sre-115140	Sporisorium reilianum	51.02	1.00e-08	55.50
IUUC-Ssc-115645	Sus scrofa	42.00	1.00e-09	58.20
IUUC-Tsy-119214	Tarsius syrichta	42.00	1.00e-09	58.50
IUUC-Tca-121596	Theobroma cacao	87.56	2.00e-114	404.00
IUUC-Tae-122704	Triticum aestivum	76.68	6.00e-91	325.00
IUUC-Tur-126461	Triticum urartu	61.66	1.00e-69	254.00
IUUC-Uma-129425	Ustilago maydis	36.51	3.00e-07	50.40
IUUC-Vvi-131614	Vitis vinifera	83.10	8.00e-108	381.00
IUUC-Xtr-132307	Xenopus tropicalis	42.00	9.00e-10	58.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence