iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-21	76.3	81	111
UBD/Beta-Prp	2.00e-48	165.5	80	300

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 7    tclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           tc+++ s+  +l+sG+ ++t+ +WDl++ +l
   Q: 81   TCVDLnSTsMYLASGGLNNTVNIWDLKSKRL 111
           79999866699***************98776 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.ghedsvlsl 100
            tcv+    + +la+g+ ++t+ +wd++++ l rsl++h+ evt+v ++ ++ ++++gs  + i + ++ t++    +  g ++ v+ +
   Q: 80   QTCVDLNSTSMYLASGGLNNTVNIWDLKSKRLHRSLKDHKREVTCVAYNWNDCYIASGSLSGEIILHSVTTNTSSTPFGhGSKQPVRHI 168
           589999999******************************************99**************999776665554499******* PP
   S: 101  sfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls 187
           ++s   ++ l s s+  ++ +wd+++++ +++++s h++  ++++++p +  l+v+ +lD+ + l+d +++kl++tl    + + + ++
   Q: 169  KYSLfRKSLLGSVSDNGVVTLWDVNSQSAYHSFDSTHKAPASGLCFSPVNeLLFVTIGLDKRIILYDTSSKKLVKTLVA--DTPLTAVD 255
           ****7778899***************************************999************************65..899***** PP
   S: 188  fdsngkelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfs 231
           f ++g +l+ gs  g++  +dl+  ++ v+t  +h++ v++++f 
   Q: 256  FMPDGASLAIGSSRGKIYQYDLRmLKSPVKTISAHKTSVQCIAFQ 300
           ***********************98889***************98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MQENLRFASS GDDVKIWDAS FLTLVDKFNP HTSPHGISSI CWSSNNNFLV TASSGGDKIV 60
VSSCKCKPVP LLELAEGQKQ TCVDLNSTSM YLASGGLNNT VNIWDLKSKR LHRSLKDHKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAACTTC TTTGCACCAC CCCGGCGTGG GCTGCCACCC AGCAAGCGCT GGTGGAGCGC 60
CCGCGGCACC GCCTCTCCGT GACGTCATGT GAGGCGGGAC TTCCGGCCGC CTAAGTTTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0045177--C:apical part of cell
GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000242--C:pericentriolar material
GO:0000922--C:spindle pole
GO:0071539--P:protein localization to centrosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000871	Aegilops tauschii	35.14	6.00e-15	76.60
IUUC-Aml-002397	Ailuropoda melanoleuca	84.24	0.00e+00	1107.00
IUUC-Atr-002464	Amborella trichopoda	31.53	4.00e-37	149.00
IUUC-Apl-003870	Anas platyrhynchos	63.06	0.00e+00	832.00
IUUC-Aca-004925	Anolis carolinensis	60.12	0.00e+00	764.00
IUUC-Aly-005931	Arabidopsis lyrata	32.37	1.00e-38	154.00
IUUC-Ath-006681	Arabidopsis thaliana	32.06	5.00e-38	152.00
IUUC-Ame-010906	Astyanax mexicanus	44.87	6.00e-149	521.00
IUUC-Bta-013389	Bos taurus	84.39	0.00e+00	1105.00
IUUC-Bdi-014340	Brachypodium distachyon	29.74	1.00e-35	145.00
IUUC-Bol-016282	Brassica oleracea	31.73	2.00e-38	154.00
IUUC-Bra-017178	Brassica rapa	31.73	5.00e-38	152.00
IUUC-Cja-019541	Callithrix jacchus	85.45	0.00e+00	1141.00
IUUC-Cfa-021218	Canis familiaris	83.64	0.00e+00	1101.00
IUUC-Cpo-021697	Cavia porcellus	79.88	0.00e+00	1065.00
IUUC-Csa-023620	Chlorocebus sabaeus	85.15	0.00e+00	1150.00
IUUC-Cho-025105	Choloepus hoffmanni	79.23	0.00e+00	864.00
IUUC-Cin-025293	Ciona intestinalis	41.47	7.00e-63	235.00
IUUC-Csv-026234	Ciona savignyi	35.88	3.00e-50	191.00
IUUC-Dre-028251	Danio rerio	44.35	4.00e-139	488.00
IUUC-Dno-029281	Dasypus novemcinctus	81.82	0.00e+00	904.00
IUUC-Dor-031020	Dipodomys ordii	72.14	3.00e-164	571.00
IUUC-Ete-033113	Echinops telfairi	81.28	0.00e+00	650.00
IUUC-Eca-034230	Equus caballus	85.63	0.00e+00	1109.00
IUUC-Eeu-034671	Erinaceus europaeus	69.00	0.00e+00	735.00
IUUC-Fca-035775	Felis catus	85.45	0.00e+00	1134.00
IUUC-Fal-037557	Ficedula albicollis	61.28	0.00e+00	757.00
IUUC-Gmo-038586	Gadus morhua	58.55	3.00e-100	358.00
IUUC-Gga-040153	Gallus gallus	63.56	0.00e+00	844.00
IUUC-Gac-041385	Gasterosteus aculeatus	42.97	7.00e-132	464.00
IUUC-Gma-042844	Glycine max	32.60	9.00e-41	162.00
IUUC-Ggo-044576	Gorilla gorilla	85.61	0.00e+00	1174.00
IUUC-Hsa-046198	Homo sapiens	85.61	0.00e+00	1174.00
IUUC-Hvu-047794	Hordeum vulgare	35.14	2.00e-15	75.10
IUUC-Lch-050561	Latimeria chalumnae	49.32	1.00e-154	540.00
IUUC-Lpe-051469	Leersia perrieri	29.74	5.00e-34	139.00
IUUC-Loc-052816	Lepisosteus oculatus	48.68	5.00e-153	534.00
IUUC-Laf-053880	Loxodonta africana	82.15	0.00e+00	1050.00
IUUC-Mcc-054977	Macaca mulatta	85.00	0.00e+00	1149.00
IUUC-Meu-056141	Macropus eugenii	57.54	4.00e-161	561.00
IUUC-Mtr-058441	Medicago truncatula	32.51	3.00e-40	160.00
IUUC-Mga-060141	Meleagris gallopavo	61.90	0.00e+00	808.00
IUUC-Mmr-061201	Microcebus murinus	85.45	0.00e+00	1159.00
IUUC-Mdo-061855	Monodelphis domestica	69.75	0.00e+00	905.00
IUUC-Mmu-064342	Mus musculus	94.39	0.00e+00	1260.00
IUUC-Mac-065368	Musa acuminata	28.96	1.00e-36	148.00
IUUC-Mpu-066191	Mustela putorius furo	83.64	0.00e+00	1103.00
IUUC-Mlu-067310	Myotis lucifugus	84.39	0.00e+00	1107.00
IUUC-Nle-069990	Nomascus leucogenys	85.91	0.00e+00	1179.00
IUUC-Opr-070336	Ochotona princeps	77.42	0.00e+00	993.00
IUUC-Ont-071675	Oreochromis niloticus	41.70	4.00e-136	478.00
IUUC-Oan-072772	Ornithorhynchus anatinus	68.18	0.00e+00	751.00
IUUC-Ocu-074095	Oryctolagus cuniculus	86.06	0.00e+00	1145.00
IUUC-Oba-075327	Oryza barthii	30.07	2.00e-35	144.00
IUUC-Obr-076119	Oryza brachyantha	30.39	6.00e-36	145.00
IUUC-Ogl-077820	Oryza glaberrima	29.74	8.00e-35	142.00
IUUC-Ogu-078679	Oryza glumaepatula	30.07	2.00e-35	144.00
IUUC-Oin-079891	Oryza indica	30.07	1.00e-35	145.00
IUUC-Olo-080414	Oryza longistaminata	32.88	1.00e-33	138.00
IUUC-Ome-081888	Oryza meridionalis	30.39	9.00e-36	145.00
IUUC-Oni-082417	Oryza nivara	30.07	2.00e-35	144.00
IUUC-Opu-083393	Oryza punctata	30.39	2.00e-35	144.00
IUUC-Oru-084698	Oryza rufipogon	30.07	1.00e-35	145.00
IUUC-Osa-086121	Oryza sativa	30.07	2.00e-35	144.00
IUUC-Ola-086806	Oryzias latipes	39.67	4.00e-134	472.00
IUUC-Olu-087591	Ostreococcus lucimarinus	24.28	3.00e-15	76.30
IUUC-Oga-088622	Otolemur garnettii	84.29	0.00e+00	1130.00
IUUC-Oar-090391	Ovis aries	80.94	0.00e+00	938.00
IUUC-Ptr-091036	Pan troglodytes	85.61	0.00e+00	1172.00
IUUC-Pan-092576	Papio anubis	85.30	0.00e+00	1153.00
IUUC-Psi-093450	Pelodiscus sinensis	65.67	0.00e+00	845.00
IUUC-Pma-094101	Petromyzon marinus	54.02	3.00e-103	367.00
IUUC-Ppa-095636	Physcomitrella patens	31.94	3.00e-41	163.00
IUUC-Pfo-097142	Poecilia formosa	57.33	7.00e-106	377.00
IUUC-Pab-097829	Pongo abelii	85.45	0.00e+00	1168.00
IUUC-Pop-099687	Populus trichocarpa	32.06	2.00e-39	157.00
IUUC-Pca-100217	Procavia capensis	79.76	0.00e+00	672.00
IUUC-Ppe-101502	Prunus persica	31.73	5.00e-39	156.00
IUUC-Pva-102736	Pteropus vampyrus	84.09	0.00e+00	1118.00
IUUC-Sha-107003	Sarcophilus harrisii	69.30	0.00e+00	896.00
IUUC-Smo-109328	Selaginella moellendorffii	32.37	6.00e-38	152.00
IUUC-Sit-109796	Setaria italica	30.29	2.00e-35	144.00
IUUC-Sly-110941	Solanum lycopersicum	30.29	5.00e-36	146.00
IUUC-Stu-112314	Solanum tuberosum	30.62	5.00e-36	146.00
IUUC-Sar-112926	Sorex araneus	77.73	0.00e+00	1028.00
IUUC-Sbi-113822	Sorghum bicolor	32.02	3.00e-25	110.00
IUUC-Ssc-116242	Sus scrofa	86.06	0.00e+00	628.00
IUUC-Tgu-116765	Taeniopygia guttata	61.80	0.00e+00	779.00
IUUC-Tru-117738	Takifugu rubripes	43.90	1.00e-150	526.00
IUUC-Tsy-118856	Tarsius syrichta	81.14	0.00e+00	1014.00
IUUC-Tni-120871	Tetraodon nigroviridis	43.83	5.00e-150	524.00
IUUC-Tca-120965	Theobroma cacao	30.30	8.00e-38	152.00
IUUC-Tae-124830	Triticum aestivum	28.97	2.00e-37	150.00
IUUC-Tur-126840	Triticum urartu	29.49	1.00e-36	148.00
IUUC-Ttr-128551	Tursiops truncatus	82.73	0.00e+00	1075.00
IUUC-Vpa-130324	Vicugna pacos	85.00	0.00e+00	1098.00
IUUC-Vvi-131699	Vitis vinifera	31.75	2.00e-38	154.00
IUUC-Xtr-131956	Xenopus tropicalis	57.94	0.00e+00	771.00
IUUC-Xma-132982	Xiphophorus maculatus	57.24	1.00e-105	377.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence