iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062904

UUCD1 version

UUC-MoD-00835

Ensembl Protein ID

ENSMODP00000018527.3

UniProt Accession

F7DLN9; F7DLN9_MONDO

Protein Name

Uncharacterized protein

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014814.3	ENSMODT00000018860.3	ENSMODP00000018527.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.20e-07	30.5	12	53

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f + p++ pCgH f+  Cl + w     ++ + f+CP Cr
   Q: 12   CSICLELFHH-PVTIPCGHNFCSPCLnETW----TVQGPPFYCPQCR 53
           ********99.*******************....99**********8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAELQLTEEM TCSICLELFH HPVTIPCGHN FCSPCLNETW TVQGPPFYCP QCRTSFLTRP 60
QLQKNTALCS VVDHLQQIQS RQELGSLCEE AKRGESWDLP SRKEGQGKEA EAVSVACDHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTAAGTTCC CTCCCCTAAA GCTAGTTTCA TTTCTCCCCG CTCCAGAGTC ACCCTACAGA 60
ATTCTCTTCC TTGAAGGTTC CTGGAAAGGG TCGCGATGGC CGAGCTGCAG CTGACCGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	56.85	0.00e+00	732.00
IUUC-Apl-004101	Anas platyrhynchos	48.53	9.00e-172	596.00
IUUC-Aca-005025	Anolis carolinensis	48.84	1.00e-177	616.00
IUUC-Bta-012735	Bos taurus	59.29	0.00e+00	764.00
IUUC-Cja-019996	Callithrix jacchus	47.79	3.00e-117	415.00
IUUC-Cfa-020466	Canis familiaris	57.41	0.00e+00	753.00
IUUC-Cpo-021737	Cavia porcellus	54.92	0.00e+00	707.00
IUUC-Csa-023217	Chlorocebus sabaeus	57.28	0.00e+00	745.00
IUUC-Cho-024346	Choloepus hoffmanni	41.29	1.00e-53	203.00
IUUC-Dno-030082	Dasypus novemcinctus	58.57	0.00e+00	750.00
IUUC-Dor-030335	Dipodomys ordii	43.08	2.00e-98	353.00
IUUC-Ete-032923	Echinops telfairi	56.08	0.00e+00	642.00
IUUC-Eca-033411	Equus caballus	56.99	0.00e+00	730.00
IUUC-Eeu-034656	Erinaceus europaeus	53.87	5.00e-117	414.00
IUUC-Fca-035371	Felis catus	58.82	0.00e+00	756.00
IUUC-Fal-037008	Ficedula albicollis	45.68	1.00e-164	573.00
IUUC-Gmo-038668	Gadus morhua	35.53	7.00e-111	394.00
IUUC-Gga-040608	Gallus gallus	48.20	3.00e-163	568.00
IUUC-Gac-041409	Gasterosteus aculeatus	34.64	3.00e-116	412.00
IUUC-Ggo-044518	Gorilla gorilla	57.16	0.00e+00	728.00
IUUC-Hsa-045828	Homo sapiens	57.12	0.00e+00	741.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	50.16	5.00e-176	610.00
IUUC-Lch-050478	Latimeria chalumnae	41.47	2.00e-78	287.00
IUUC-Loc-052864	Lepisosteus oculatus	37.20	1.00e-117	417.00
IUUC-Laf-054325	Loxodonta africana	55.67	2.00e-119	422.00
IUUC-Mcc-054920	Macaca mulatta	57.28	0.00e+00	744.00
IUUC-Meu-056367	Macropus eugenii	82.86	5.00e-85	308.00
IUUC-Mga-059975	Meleagris gallopavo	48.51	3.00e-163	568.00
IUUC-Mmr-060748	Microcebus murinus	58.54	0.00e+00	738.00
IUUC-Mmu-063891	Mus musculus	56.41	0.00e+00	745.00
IUUC-Mpu-066473	Mustela putorius furo	56.75	0.00e+00	747.00
IUUC-Mlu-068185	Myotis lucifugus	56.50	0.00e+00	727.00
IUUC-Nle-070177	Nomascus leucogenys	57.27	0.00e+00	748.00
IUUC-Opr-070558	Ochotona princeps	46.54	4.00e-108	384.00
IUUC-Ont-071368	Oreochromis niloticus	36.97	6.00e-113	401.00
IUUC-Ocu-074461	Oryctolagus cuniculus	45.19	2.00e-145	509.00
IUUC-Oba-075064	Oryza barthii	32.09	3.00e-08	53.90
IUUC-Ola-087315	Oryzias latipes	24.70	5.00e-53	202.00
IUUC-Oga-088937	Otolemur garnettii	54.64	0.00e+00	698.00
IUUC-Oar-089781	Ovis aries	58.22	2.00e-146	512.00
IUUC-Ptr-090771	Pan troglodytes	57.12	0.00e+00	728.00
IUUC-Pan-092830	Papio anubis	57.43	0.00e+00	742.00
IUUC-Psi-093664	Pelodiscus sinensis	53.69	0.00e+00	658.00
IUUC-Pma-094147	Petromyzon marinus	27.27	5.00e-62	232.00
IUUC-Pfo-096528	Poecilia formosa	35.56	6.00e-117	414.00
IUUC-Pab-097588	Pongo abelii	56.51	0.00e+00	732.00
IUUC-Pca-100890	Procavia capensis	57.81	0.00e+00	722.00
IUUC-Pva-102314	Pteropus vampyrus	58.67	0.00e+00	727.00
IUUC-Rno-105234	Rattus norvegicus	55.98	0.00e+00	712.00
IUUC-Sce-106362	Saccharomyces cerevisiae	42.42	2.00e-09	56.60
IUUC-Sha-106807	Sarcophilus harrisii	70.12	0.00e+00	880.00
IUUC-Sar-113283	Sorex araneus	42.74	6.00e-90	324.00
IUUC-Ssc-115878	Sus scrofa	58.68	2.00e-75	275.00
IUUC-Tgu-117026	Taeniopygia guttata	44.66	4.00e-131	461.00
IUUC-Tru-117794	Takifugu rubripes	33.85	4.00e-99	355.00
IUUC-Tbe-127580	Tupaia belangeri	50.66	3.00e-96	345.00
IUUC-Ttr-128648	Tursiops truncatus	55.62	3.00e-141	495.00
IUUC-Vpa-130254	Vicugna pacos	77.84	2.00e-87	316.00
IUUC-Vvi-131424	Vitis vinifera	36.19	6.00e-10	58.20
IUUC-Xtr-132892	Xenopus tropicalis	43.10	2.00e-75	275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence