iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068204

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02017045

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000000133.2	ENSMLUT00000000133.2	ENSMLUP00000000122.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	85.21	0.00e+00	1826.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.53	8.00e-29	124.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

VRRFKRKHLT AIDCQHLSRS HLAVTQPFSQ RWTNRDPNHG LYPRPRTKRG TRGQGCQRYI 60
TDFFPAGQRR CTNDMAKCNS VGQDSSKDSE GEMMFVTESN CALSQEDDGE ARLGSSGSAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGACGGT TTAAGCGGAA GCATCTTACA GCCATCGACT GCCAACATTT GTCTCGAAGT 60
CACTTGGCTG TGACCCAGCC CTTCAGTCAA AGATGGACAA ACAGAGACCC GAACCATGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	45.65	1.00e-03	40.00
IUUC-Aml-001396	Ailuropoda melanoleuca	87.88	0.00e+00	1859.00
IUUC-Apl-003317	Anas platyrhynchos	46.74	0.00e+00	904.00
IUUC-Aca-004498	Anolis carolinensis	52.00	0.00e+00	882.00
IUUC-Ath-007293	Arabidopsis thaliana	24.56	2.00e-05	45.10
IUUC-Ani-009226	Aspergillus nidulans	23.83	5.80e-02	33.50
IUUC-Ate-010526	Aspergillus terreus	40.82	6.00e-03	37.00
IUUC-Ame-011808	Astyanax mexicanus	53.33	4.00e-117	414.00
IUUC-Bta-013250	Bos taurus	84.08	0.00e+00	1776.00
IUUC-Bol-015348	Brassica oleracea	24.33	6.30e-02	33.50
IUUC-Cja-019638	Callithrix jacchus	85.21	0.00e+00	1844.00
IUUC-Cfa-020195	Canis familiaris	88.41	0.00e+00	1762.00
IUUC-Cpo-022269	Cavia porcellus	81.49	0.00e+00	1699.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	4.00e-08	53.90
IUUC-Csa-024060	Chlorocebus sabaeus	86.24	0.00e+00	1640.00
IUUC-Cho-025003	Choloepus hoffmanni	86.72	0.00e+00	702.00
IUUC-Cin-025694	Ciona intestinalis	26.48	2.00e-29	123.00
IUUC-Cne-027074	Cryptococcus neoformans	22.09	2.00e-01	31.60
IUUC-Dre-028083	Danio rerio	47.84	0.00e+00	792.00
IUUC-Dno-029203	Dasypus novemcinctus	82.10	0.00e+00	1655.00
IUUC-Dor-030477	Dipodomys ordii	80.04	0.00e+00	740.00
IUUC-Ete-032861	Echinops telfairi	83.51	0.00e+00	1752.00
IUUC-Eca-033205	Equus caballus	88.27	0.00e+00	1903.00
IUUC-Eeu-034784	Erinaceus europaeus	79.04	0.00e+00	1103.00
IUUC-Fca-035797	Felis catus	87.93	0.00e+00	1859.00
IUUC-Gmo-038855	Gadus morhua	45.83	7.00e-126	444.00
IUUC-Gga-040326	Gallus gallus	48.52	0.00e+00	919.00
IUUC-Gac-042240	Gasterosteus aculeatus	40.21	0.00e+00	688.00
IUUC-Ggo-045050	Gorilla gorilla	84.51	0.00e+00	1769.00
IUUC-Hsa-046650	Homo sapiens	85.11	0.00e+00	1782.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	86.56	0.00e+00	677.00
IUUC-Lch-050231	Latimeria chalumnae	42.91	8.00e-168	583.00
IUUC-Lpe-051609	Leersia perrieri	30.43	4.00e-03	38.10
IUUC-Loc-051884	Lepisosteus oculatus	47.01	0.00e+00	916.00
IUUC-Lma-053267	Leptosphaeria maculans	24.33	4.00e-04	40.80
IUUC-Laf-053843	Loxodonta africana	85.99	0.00e+00	1816.00
IUUC-Mcc-055570	Macaca mulatta	86.07	0.00e+00	1818.00
IUUC-Meu-056798	Macropus eugenii	62.91	3.00e-145	509.00
IUUC-Mtr-057915	Medicago truncatula	23.48	2.00e-02	35.40
IUUC-Mga-059648	Meleagris gallopavo	49.13	0.00e+00	881.00
IUUC-Mmr-060757	Microcebus murinus	83.19	0.00e+00	1729.00
IUUC-Mdo-061913	Monodelphis domestica	66.80	0.00e+00	1316.00
IUUC-Mmu-064337	Mus musculus	83.13	0.00e+00	1790.00
IUUC-Mac-064479	Musa acuminata	24.90	1.00e-04	42.40
IUUC-Mpu-066483	Mustela putorius furo	85.40	0.00e+00	1849.00
IUUC-Ncr-068735	Neurospora crassa	25.51	8.70e-01	29.60
IUUC-Nle-070053	Nomascus leucogenys	85.78	0.00e+00	1767.00
IUUC-Opr-070588	Ochotona princeps	79.69	0.00e+00	1651.00
IUUC-Ont-072655	Oreochromis niloticus	43.98	0.00e+00	694.00
IUUC-Oan-073351	Ornithorhynchus anatinus	59.06	0.00e+00	1221.00
IUUC-Ocu-074465	Oryctolagus cuniculus	84.06	0.00e+00	1717.00
IUUC-Ogu-078861	Oryza glumaepatula	48.72	6.00e-03	35.40
IUUC-Olo-080505	Oryza longistaminata	32.94	1.00e-03	40.40
IUUC-Oni-082634	Oryza nivara	48.72	6.00e-03	35.40
IUUC-Opu-083155	Oryza punctata	47.50	8.00e-03	36.20
IUUC-Olu-087831	Ostreococcus lucimarinus	29.58	2.00e-50	195.00
IUUC-Oga-089088	Otolemur garnettii	82.73	0.00e+00	1725.00
IUUC-Oar-089870	Ovis aries	83.03	0.00e+00	1721.00
IUUC-Ptr-090957	Pan troglodytes	85.54	0.00e+00	1761.00
IUUC-Pan-092632	Papio anubis	85.97	0.00e+00	1767.00
IUUC-Psi-093035	Pelodiscus sinensis	52.81	0.00e+00	1059.00
IUUC-Pno-094870	Phaeosphaeria nodorum	24.75	2.00e-03	38.50
IUUC-Pfo-096902	Poecilia formosa	41.61	0.00e+00	657.00
IUUC-Pab-098206	Pongo abelii	85.48	0.00e+00	1661.00
IUUC-Pop-100065	Populus trichocarpa	38.78	1.90e-02	33.50
IUUC-Pca-100238	Procavia capensis	79.22	0.00e+00	1657.00
IUUC-Pva-103182	Pteropus vampyrus	84.94	0.00e+00	1753.00
IUUC-Pte-104033	Pyrenophora teres	24.81	3.00e-03	37.70
IUUC-Pyt-104599	Pyrenophora triticirepentis	24.91	3.00e-03	37.70
IUUC-Rno-105141	Rattus norvegicus	82.46	0.00e+00	1776.00
IUUC-Sce-106341	Saccharomyces cerevisiae	26.60	4.00e-03	37.00
IUUC-Sha-106827	Sarcophilus harrisii	64.86	0.00e+00	1374.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	31.27	2.00e-32	134.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.53	2.00e-29	124.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	27.66	3.00e-05	44.30
IUUC-Stu-112162	Solanum tuberosum	32.26	2.00e-03	36.60
IUUC-Sre-115025	Sporisorium reilianum	34.28	2.00e-37	151.00
IUUC-Ssc-116188	Sus scrofa	86.81	0.00e+00	1158.00
IUUC-Tgu-116612	Taeniopygia guttata	56.40	5.00e-158	550.00
IUUC-Tsy-119560	Tarsius syrichta	81.05	8.00e-114	405.00
IUUC-Tni-120734	Tetraodon nigroviridis	43.73	0.00e+00	662.00
IUUC-Tca-121338	Theobroma cacao	25.00	2.00e-04	42.40
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tme-127009	Tuber melanosporum	26.14	5.00e-03	37.00
IUUC-Tbe-127431	Tupaia belangeri	84.33	0.00e+00	1530.00
IUUC-Ttr-128744	Tursiops truncatus	83.33	0.00e+00	1726.00
IUUC-Uma-129536	Ustilago maydis	33.70	5.00e-39	156.00
IUUC-Vpa-130123	Vicugna pacos	74.70	1.00e-99	357.00
IUUC-Vvi-131025	Vitis vinifera	32.67	5.40e-02	33.90
IUUC-Xtr-132902	Xenopus tropicalis	56.58	0.00e+00	964.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence