iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
PINA	HINT
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-20	72.0	236	273

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvllk 37
           gHt  v+ ++f +++++v+++ Dg +k+W++ +g++++
   Q: 236  GHTKTVSYVRFlDGGTVVTAGTDGCLKLWSVEDGRVIR 273
           8**********65599******************9887 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions in association with RUP1 as repressor of UV-B-induced photomorphogenesis mediated by UVR8 and HY5. Plays a crucial negative feedback regulatory role downstream of UVR8-COP1 to inhibit UVR8 function, balance UV-B-specific responses and ensure normal plant growth. Is involved in the regulation of photoperiodic flowering and vegetative development. May act as negative regulator of photoperiodic flowering by suppressing flowering through the action of CONSTANS (CO) and FLOWERING LOCUS T (FT).

Protein Sequence
(Fasta)

MNTLHPHKQQ QEQAQQQEEA RYEWDLSLST VVSSSSSSAS DVIGAIEFDP TDNIVATAGI 60
SRKIRFYGLP SLLRNNAVSG TGVSFVDQAT ACEYYICTPA KLSSLRWRPG SGGRVIGSGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGAATAAA AATTCATACG TGGATTAGTA ATAAACCCAA TTATTTACTG AGGGAAAAAC 60
AAAAAGCCAT ATTAAAATGA ATATTATATT CTAATGTATT AAACTATTAA TAAAAAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0287--Flowering
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0009658--P:chloroplast organization
GO:0009908--P:flower development
GO:0043496--P:regulation of protein homodimerization activity
GO:0010224--P:response to UV-B

KEGG

ath:AT5G23730

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002851	Amborella trichopoda	45.99	6.00e-84	303.00
IUUC-Aly-005431	Arabidopsis lyrata	95.11	0.00e+00	658.00
IUUC-Bdi-014616	Brachypodium distachyon	47.00	3.00e-62	231.00
IUUC-Bol-016424	Brassica oleracea	90.62	5.00e-159	553.00
IUUC-Ogl-077687	Oryza glaberrima	46.47	3.00e-62	231.00
IUUC-Oin-079632	Oryza indica	46.20	3.00e-62	231.00
IUUC-Ome-081923	Oryza meridionalis	45.61	2.00e-59	222.00
IUUC-Oni-082448	Oryza nivara	46.49	2.00e-63	236.00
IUUC-Oru-085278	Oryza rufipogon	45.61	2.00e-59	222.00
IUUC-Pop-099510	Populus trichocarpa	64.13	5.00e-121	426.00
IUUC-Ppe-102088	Prunus persica	64.76	6.00e-119	419.00
IUUC-Sly-111536	Solanum lycopersicum	57.32	1.00e-111	395.00
IUUC-Stu-112915	Solanum tuberosum	58.26	3.00e-115	407.00
IUUC-Tca-120952	Theobroma cacao	64.10	2.00e-127	448.00
IUUC-Tae-123036	Triticum aestivum	46.55	9.00e-67	246.00
IUUC-Vvi-131711	Vitis vinifera	65.24	4.00e-122	431.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence