iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010302

Ensembl Protein ID

CADATEAP00002682

UniProt Accession

Q0CXK6; Q0CXK6_ASPTN

Genbank Protein ID

EAU38335.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CH476595

Gene Name

ATEG_01578

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00002682	CADATEAT00002682	CADATEAP00002682

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-35	116.3	50	86
UBD/Beta-Prp	5.70e-76	254.6	3	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f ++ +l+vsG+dD +ikvW++ t ++l
   Q: 50   HDGPVRGIDFhPTqPLFVSGGDDYKIKVWSTQTRRCL 86
           99*********888****************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ ++f+p+++++v+g++D+ ikvw+ +t+ c+ tl+gh d+
   Q: 3    TKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRGIDFHPTQPLFVSGGDDYKIKVWSTQTRRCLFTLNGHLDY 95
           67889999************************************************************************************* PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....................... 166
           v+++ f+ +  +++s+s+d+tir+w++++++ +  t +gh++ v+c+++hp+++l++s+slD+ vr+Wd+                       
   Q: 96   VRTVFFHHELPWILSASDDQTIRIWNWQNRSLIC-TMTGHNHYVMCAQFHPTEDLIASASLDQSVRIWDIsglrkkhsapttmsfedqmaran 187
           *********************************9.********************************************************** PP
   S: 167  ........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
                   +t+ +++   +gh++ v+++sf+++ + +vs+++d+ +klw ++ ++   v+t++gh +n +   f+p++++++s+++D++ir+W
   Q: 188  pnqadmfgNTDAVVKFVLEGHDRGVNWVSFHPTLPLIVSAGDDRLIKLWRMSDTKAweVDTCRGHFQNASACLFHPHQDLILSVGEDKTIRVW 280
           *9999997777777766777********************************777668*********************************** PP
   S: 250  dlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           dl +++ ++++++  ++++ +a+ +++ n +++g  d  v+++kl++++p
   Q: 281  DLNKRTSVQSFKRDLDRFWVIAA-HPEINLFAAG-HDTGVMVFKLERERP 328
           ***********************.5555555444.589*******98775 PP

Organism

Aspergillus terreus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFESKSS RAKGIAFHPK RPWILVSLHS STIQLWDYRM GTLIDRFEEH DGPVRGIDFH 60
PTQPLFVSGG DDYKIKVWST QTRRCLFTLN GHLDYVRTVF FHHELPWILS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTCACCA AGGTATGCCT ACTCCTCCCT GCCAGGTCTC CCCATGTCTA CATGGTTCTT 60
TCGCTACGAG GGCCTCAATT GACCTCAATT TTTGTCACAG TTTGAGTCGA AATCTTCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	47.66	0.00e+00	1146.00
IUUC-Aml-001758	Ailuropoda melanoleuca	49.28	0.00e+00	1233.00
IUUC-Atr-002493	Amborella trichopoda	47.48	0.00e+00	1118.00
IUUC-Apl-003385	Anas platyrhynchos	44.30	0.00e+00	930.00
IUUC-Aca-005154	Anolis carolinensis	71.36	5.00e-93	331.00
IUUC-Aly-006020	Arabidopsis lyrata	54.63	0.00e+00	961.00
IUUC-Ath-007360	Arabidopsis thaliana	47.71	0.00e+00	1127.00
IUUC-Ago-007992	Ashbya gossypii	53.85	0.00e+00	1303.00
IUUC-Acl-008027	Aspergillus clavatus	90.63	0.00e+00	2213.00
IUUC-Afl-008644	Aspergillus flavus	91.63	0.00e+00	2221.00
IUUC-Afu-008964	Aspergillus fumigatus	91.87	0.00e+00	2261.00
IUUC-Ani-009379	Aspergillus nidulans	90.46	0.00e+00	2226.00
IUUC-Ang-009756	Aspergillus niger	92.79	0.00e+00	2258.00
IUUC-Aor-010174	Aspergillus oryzae	91.54	0.00e+00	2217.00
IUUC-Ame-011229	Astyanax mexicanus	47.52	0.00e+00	1201.00
IUUC-Bgr-012300	Blumeria graminis	75.11	0.00e+00	1871.00
IUUC-Bta-012524	Bos taurus	49.64	0.00e+00	1227.00
IUUC-Bci-013781	Botrytis cinerea	79.04	0.00e+00	1978.00
IUUC-Bdi-014549	Brachypodium distachyon	47.21	0.00e+00	1139.00
IUUC-Bol-015925	Brassica oleracea	48.10	0.00e+00	1135.00
IUUC-Bra-016978	Brassica rapa	55.35	0.00e+00	968.00
IUUC-Cel-018115	Caenorhabditis elegans	51.42	0.00e+00	898.00
IUUC-Cja-019107	Callithrix jacchus	48.43	0.00e+00	1209.00
IUUC-Cfa-020675	Canis familiaris	48.98	0.00e+00	1206.00
IUUC-Cpo-021813	Cavia porcellus	49.80	0.00e+00	1244.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	55.78	0.00e+00	990.00
IUUC-Csa-023523	Chlorocebus sabaeus	49.64	0.00e+00	1246.00
IUUC-Cho-024704	Choloepus hoffmanni	38.96	2.00e-158	551.00
IUUC-Cin-025572	Ciona intestinalis	47.65	0.00e+00	1191.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	77.96	0.00e+00	1940.00
IUUC-Cne-027053	Cryptococcus neoformans	56.26	0.00e+00	1362.00
IUUC-Cme-027222	Cyanidioschyzon merolae	41.92	2.00e-141	495.00
IUUC-Dre-027421	Danio rerio	48.46	0.00e+00	1218.00
IUUC-Dno-029303	Dasypus novemcinctus	49.84	0.00e+00	1244.00
IUUC-Dor-030290	Dipodomys ordii	46.67	7.00e-147	513.00
IUUC-Dse-031543	Dothistroma septosporum	74.10	0.00e+00	1824.00
IUUC-Dme-031945	Drosophila melanogaster	56.02	0.00e+00	963.00
IUUC-Ete-032873	Echinops telfairi	47.05	0.00e+00	1076.00
IUUC-Eca-033773	Equus caballus	48.43	0.00e+00	1196.00
IUUC-Eeu-034874	Erinaceus europaeus	37.84	2.00e-173	601.00
IUUC-Fca-035739	Felis catus	48.87	0.00e+00	1219.00
IUUC-Fal-037263	Ficedula albicollis	45.67	0.00e+00	1092.00
IUUC-Fox-037738	Fusarium oxysporum	77.00	0.00e+00	1988.00
IUUC-Fso-038153	Fusarium solani	77.41	0.00e+00	1976.00
IUUC-Gmo-039602	Gadus morhua	45.88	0.00e+00	1135.00
IUUC-Ggr-039931	Gaeumannomyces graminis	75.29	0.00e+00	1888.00
IUUC-Gga-040590	Gallus gallus	49.04	0.00e+00	1242.00
IUUC-Gac-041318	Gasterosteus aculeatus	47.79	0.00e+00	1207.00
IUUC-Gma-043354	Glycine max	55.60	0.00e+00	971.00
IUUC-Ggo-045029	Gorilla gorilla	49.28	0.00e+00	1237.00
IUUC-Hsa-046078	Homo sapiens	49.36	0.00e+00	1239.00
IUUC-Hvu-047556	Hordeum vulgare	47.05	0.00e+00	1138.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	41.84	0.00e+00	682.00
IUUC-Kpa-049256	Komagataella pastoris	56.59	0.00e+00	1412.00
IUUC-Lch-049706	Latimeria chalumnae	49.15	0.00e+00	1213.00
IUUC-Lpe-051316	Leersia perrieri	55.10	0.00e+00	974.00
IUUC-Loc-051867	Lepisosteus oculatus	39.42	0.00e+00	830.00
IUUC-Lma-053138	Leptosphaeria maculans	76.12	0.00e+00	1894.00
IUUC-Laf-053510	Loxodonta africana	49.51	0.00e+00	1240.00
IUUC-Mcc-055836	Macaca mulatta	49.56	0.00e+00	1241.00
IUUC-Meu-056238	Macropus eugenii	51.62	0.00e+00	702.00
IUUC-Mor-057172	Magnaporthe oryzae	76.83	0.00e+00	1949.00
IUUC-Mpo-057300	Magnaporthe poae	74.67	0.00e+00	1895.00
IUUC-Mtr-058248	Medicago truncatula	47.89	0.00e+00	1153.00
IUUC-Mla-059019	Melampsora laricipopulina	57.43	0.00e+00	1437.00
IUUC-Mga-059499	Meleagris gallopavo	49.04	0.00e+00	1238.00
IUUC-Mvi-060336	Microbotryum violaceum	56.50	0.00e+00	1405.00
IUUC-Mmr-061102	Microcebus murinus	49.28	0.00e+00	1231.00
IUUC-Mdo-062594	Monodelphis domestica	50.00	0.00e+00	1253.00
IUUC-Mmu-063736	Mus musculus	49.48	0.00e+00	1236.00
IUUC-Mac-065398	Musa acuminata	45.42	0.00e+00	1041.00
IUUC-Mpu-066701	Mustela putorius furo	48.48	0.00e+00	1231.00
IUUC-Mlu-067392	Myotis lucifugus	49.39	0.00e+00	1233.00
IUUC-Nfi-068270	Neosartorya fischeri	91.79	0.00e+00	2221.00
IUUC-Ncr-068892	Neurospora crassa	77.38	0.00e+00	1933.00
IUUC-Nle-069634	Nomascus leucogenys	60.00	0.00e+00	869.00
IUUC-Opr-070952	Ochotona princeps	38.28	4.00e-172	597.00
IUUC-Ont-072488	Oreochromis niloticus	47.60	0.00e+00	1198.00
IUUC-Ocu-074211	Oryctolagus cuniculus	49.47	0.00e+00	1238.00
IUUC-Oba-075761	Oryza barthii	54.98	0.00e+00	971.00
IUUC-Obr-076429	Oryza brachyantha	54.98	0.00e+00	975.00
IUUC-Ogl-077364	Oryza glaberrima	54.98	0.00e+00	971.00
IUUC-Ogu-078257	Oryza glumaepatula	54.98	0.00e+00	968.00
IUUC-Oin-079274	Oryza indica	54.86	0.00e+00	970.00
IUUC-Olo-080466	Oryza longistaminata	55.30	0.00e+00	969.00
IUUC-Ome-081668	Oryza meridionalis	53.97	0.00e+00	821.00
IUUC-Oni-082874	Oryza nivara	55.10	0.00e+00	971.00
IUUC-Opu-083885	Oryza punctata	47.50	0.00e+00	1143.00
IUUC-Oru-084274	Oryza rufipogon	54.86	0.00e+00	969.00
IUUC-Osa-085565	Oryza sativa	54.86	0.00e+00	969.00
IUUC-Ola-086921	Oryzias latipes	47.90	0.00e+00	1194.00
IUUC-Olu-087639	Ostreococcus lucimarinus	49.03	0.00e+00	1193.00
IUUC-Oga-087991	Otolemur garnettii	47.18	0.00e+00	1161.00
IUUC-Oar-089590	Ovis aries	49.76	0.00e+00	1241.00
IUUC-Ptr-090808	Pan troglodytes	49.28	0.00e+00	1236.00
IUUC-Pan-092475	Papio anubis	49.55	0.00e+00	1234.00
IUUC-Psi-093044	Pelodiscus sinensis	45.67	0.00e+00	946.00
IUUC-Pno-094839	Phaeosphaeria nodorum	75.72	0.00e+00	1818.00
IUUC-Ppa-095254	Physcomitrella patens	51.26	0.00e+00	1235.00
IUUC-Pfo-097493	Poecilia formosa	48.50	0.00e+00	1203.00
IUUC-Pab-098497	Pongo abelii	49.56	0.00e+00	1245.00
IUUC-Pop-099992	Populus trichocarpa	55.77	0.00e+00	970.00
IUUC-Pca-100413	Procavia capensis	53.41	2.00e-179	622.00
IUUC-Ppe-101899	Prunus persica	47.86	0.00e+00	1137.00
IUUC-Pva-102126	Pteropus vampyrus	47.51	0.00e+00	1174.00
IUUC-Pgr-103376	Puccinia graminis	56.37	0.00e+00	1435.00
IUUC-Ptt-103978	Puccinia triticina	51.18	0.00e+00	1221.00
IUUC-Pte-104126	Pyrenophora teres	75.82	0.00e+00	1831.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	69.18	0.00e+00	1422.00
IUUC-Rno-105428	Rattus norvegicus	49.92	0.00e+00	1244.00
IUUC-Sce-106464	Saccharomyces cerevisiae	53.28	0.00e+00	1281.00
IUUC-Sha-107301	Sarcophilus harrisii	49.59	0.00e+00	1226.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	52.62	0.00e+00	1323.00
IUUC-Spo-108217	Schizosaccharomyces pombe	54.64	0.00e+00	1384.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	78.61	0.00e+00	1972.00
IUUC-Smo-109582	Selaginella moellendorffii	56.48	0.00e+00	1010.00
IUUC-Sit-109697	Setaria italica	54.98	0.00e+00	972.00
IUUC-Sly-111447	Solanum lycopersicum	47.43	0.00e+00	1144.00
IUUC-Stu-112564	Solanum tuberosum	47.44	0.00e+00	1142.00
IUUC-Sar-113313	Sorex araneus	37.53	9.00e-168	582.00
IUUC-Sbi-114388	Sorghum bicolor	54.98	0.00e+00	972.00
IUUC-Sre-115209	Sporisorium reilianum	61.85	0.00e+00	1116.00
IUUC-Ssc-115933	Sus scrofa	49.64	0.00e+00	1242.00
IUUC-Tgu-117109	Taeniopygia guttata	37.09	6.00e-91	326.00
IUUC-Tru-117772	Takifugu rubripes	47.95	0.00e+00	1184.00
IUUC-Tsy-119105	Tarsius syrichta	46.63	0.00e+00	932.00
IUUC-Tni-120556	Tetraodon nigroviridis	36.77	0.00e+00	782.00
IUUC-Tca-121046	Theobroma cacao	48.42	0.00e+00	1154.00
IUUC-Tre-121951	Trichoderma reesei	75.93	0.00e+00	1902.00
IUUC-Tvi-122359	Trichoderma virens	75.70	0.00e+00	1926.00
IUUC-Tae-125527	Triticum aestivum	47.86	0.00e+00	1139.00
IUUC-Tur-126754	Triticum urartu	48.19	0.00e+00	1145.00
IUUC-Tme-127170	Tuber melanosporum	76.99	0.00e+00	1961.00
IUUC-Tbe-127882	Tupaia belangeri	61.86	3.00e-120	424.00
IUUC-Ttr-128217	Tursiops truncatus	47.67	0.00e+00	1170.00
IUUC-Uma-129337	Ustilago maydis	61.61	0.00e+00	1105.00
IUUC-Vda-129828	Verticillium dahliae	74.42	0.00e+00	1894.00
IUUC-Vpa-130537	Vicugna pacos	48.91	0.00e+00	1218.00
IUUC-Vvi-130958	Vitis vinifera	56.32	0.00e+00	986.00
IUUC-Xtr-132857	Xenopus tropicalis	47.79	0.00e+00	1149.00
IUUC-Xma-133138	Xiphophorus maculatus	48.50	0.00e+00	1204.00
IUUC-Yli-134399	Yarrowia lipolytica	60.88	0.00e+00	1083.00
IUUC-Zma-135612	Zea mays	46.75	0.00e+00	1135.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence