iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007161

UUCD1 version

UUC-ArT-00497

Ensembl Protein ID

AT1G55760.1

UniProt Accession

Q680K8; Q9LFZ6; Y1576_ARATH

Genbank Protein ID

AAF79503.1; AEE33294.1; BAD43388.1; BAD43622.1; AAY34158.1

Protein Name

BTB/POZ domain-containing protein At1g55760

Genbank Nucleotide ID

AC002328; CP002684; AK175625; AK175859; BT022097

Gene Name

At1g55760; F20N2.15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G55760	AT1G55760.1	AT1G55760.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.10e-15	57.2	164	225
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.10e-06	28.0	265	292

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgk 64
           +D++++  +  + ah++vLaa+S+vF+++fl++l+e++  +++++ d+  ++++a+l+++Y g 
   Q: 164  TDITINASDGSIGAHRAVLAARSPVFRSMFLHDLKEKE-LSEINVLDMPLDACQAFLSYIY-GN 225
           79**********************************97.**********************.44 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilk 29
            N+l++l+ A ly++p+Lk ++++++ k
   Q: 265  KNVLERLQNAYLYQLPELKASCMRYLVK 292
           5************************987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MTDSAYRVDT ISRLAQWRIH NLSSSTYRKS DPFKMGLWNW HLSVEKSKML LNVKLYPEVS 60
NLTRENPPVA SFALRVVSST GERKALSHPE VIDKRIKTNE DFIWTIEVPL TGKIIIDVEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAACATAAC ACCAAACACT TTACCCTCTC TCTCTCTCCC TCTCTCCCTC TCTCCCTCTC 60
TCCCTCTCTC CCTCAACCAA AAGCAAACAA ACCCTTCAAA TGACGTAAAA GCAAAGCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF00651--BTB

SMART

SM00225--BTB

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

KEGG

ath:AT1G55760

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000482	Aegilops tauschii	52.87	5.00e-99	353.00
IUUC-Atr-003032	Amborella trichopoda	62.05	3.00e-120	423.00
IUUC-Aly-005780	Arabidopsis lyrata	95.74	0.00e+00	655.00
IUUC-Ani-009157	Aspergillus nidulans	27.01	8.00e-04	37.40
IUUC-Bdi-014916	Brachypodium distachyon	55.79	2.00e-108	384.00
IUUC-Bol-015209	Brassica oleracea	92.40	0.00e+00	640.00
IUUC-Bra-017656	Brassica rapa	92.10	0.00e+00	639.00
IUUC-Dse-031222	Dothistroma septosporum	22.47	8.00e-03	33.50
IUUC-Ggr-039827	Gaeumannomyces graminis	38.46	3.00e-04	37.70
IUUC-Gma-043637	Glycine max	72.95	2.00e-146	510.00
IUUC-Hvu-047234	Hordeum vulgare	55.59	8.00e-109	385.00
IUUC-Lpe-050919	Leersia perrieri	56.80	5.00e-110	389.00
IUUC-Mpo-057526	Magnaporthe poae	28.79	2.00e-04	38.50
IUUC-Mtr-058807	Medicago truncatula	70.09	4.00e-139	486.00
IUUC-Mac-065594	Musa acuminata	63.64	2.00e-129	454.00
IUUC-Oba-075795	Oryza barthii	54.23	3.00e-106	377.00
IUUC-Obr-076598	Oryza brachyantha	57.40	1.00e-111	395.00
IUUC-Ogl-077937	Oryza glaberrima	56.19	7.00e-109	386.00
IUUC-Ogu-078027	Oryza glumaepatula	54.52	5.00e-107	379.00
IUUC-Oin-079238	Oryza indica	56.50	1.00e-109	389.00
IUUC-Olo-080781	Oryza longistaminata	52.56	3.00e-90	323.00
IUUC-Ome-081182	Oryza meridionalis	56.19	1.00e-108	385.00
IUUC-Oni-082493	Oryza nivara	54.52	5.00e-107	379.00
IUUC-Opu-083304	Oryza punctata	56.80	6.00e-111	393.00
IUUC-Oru-084297	Oryza rufipogon	56.50	1.00e-109	389.00
IUUC-Osa-086115	Oryza sativa	56.50	1.00e-109	389.00
IUUC-Pop-099250	Populus trichocarpa	75.53	5.00e-150	522.00
IUUC-Ppe-102104	Prunus persica	74.16	1.00e-148	518.00
IUUC-Ssl-108548	Sclerotinia sclerotiorum	33.87	1.00e-03	37.00
IUUC-Sit-110098	Setaria italica	54.68	1.00e-101	362.00
IUUC-Sly-111459	Solanum lycopersicum	74.16	4.00e-151	526.00
IUUC-Stu-112229	Solanum tuberosum	73.56	1.00e-149	521.00
IUUC-Sbi-113972	Sorghum bicolor	55.59	2.00e-102	364.00
IUUC-Tca-121101	Theobroma cacao	68.26	2.00e-146	511.00
IUUC-Tae-123475	Triticum aestivum	55.29	1.00e-107	382.00
IUUC-Tur-126164	Triticum urartu	55.33	2.00e-92	331.00
IUUC-Tme-127039	Tuber melanosporum	27.94	1.00e-06	48.10
IUUC-Vvi-130972	Vitis vinifera	71.99	2.00e-122	430.00
IUUC-Yli-134535	Yarrowia lipolytica	28.71	2.00e-04	39.30
IUUC-Zma-135935	Zea mays	55.26	1.00e-99	355.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence