iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066136

Ensembl Protein ID

ENSMPUP00000017089.1

UniProt Accession

M3Z0H7; M3Z0H7_MUSPF

Genbank Protein ID

ENSMPUP00000017089

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01003113

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000017197.1	ENSMPUT00000017343.1	ENSMPUP00000017089.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-13	50.8	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MRAVLTWRDK AEQCIYDLAF KPDGMQLILA AGNRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQCVS YNPVTHQLAS CSSSDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGGCCG TGTTGACGTG GAGAGATAAA GCCGAGCAGT GGTGAGGAGT TGGGCAGTCC 60
GGGAGGAGCG GGAGGCTGAG CCGTGGCGGG GATGGCGGGA ACCCTGGCGA GAGCCCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	94.14	0.00e+00	2307.00
IUUC-Apl-003504	Anas platyrhynchos	81.90	0.00e+00	2041.00
IUUC-Aca-004767	Anolis carolinensis	82.33	0.00e+00	2069.00
IUUC-Ame-011642	Astyanax mexicanus	72.07	0.00e+00	1815.00
IUUC-Bta-012969	Bos taurus	90.27	0.00e+00	2183.00
IUUC-Cel-018670	Caenorhabditis elegans	37.60	0.00e+00	857.00
IUUC-Cja-019249	Callithrix jacchus	86.81	0.00e+00	2125.00
IUUC-Cfa-020915	Canis familiaris	94.22	0.00e+00	2249.00
IUUC-Cpo-021888	Cavia porcellus	82.25	0.00e+00	2086.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	46.11	0.00e+00	1052.00
IUUC-Csa-023533	Chlorocebus sabaeus	88.65	0.00e+00	2169.00
IUUC-Cin-025121	Ciona intestinalis	55.66	0.00e+00	1434.00
IUUC-Csv-026240	Ciona savignyi	56.40	0.00e+00	1367.00
IUUC-Dno-029685	Dasypus novemcinctus	87.68	0.00e+00	2141.00
IUUC-Dme-032005	Drosophila melanogaster	23.95	2.00e-07	51.60
IUUC-Ete-032682	Echinops telfairi	80.80	0.00e+00	1586.00
IUUC-Eca-033831	Equus caballus	93.57	0.00e+00	2308.00
IUUC-Eeu-034919	Erinaceus europaeus	87.33	0.00e+00	1032.00
IUUC-Fca-036559	Felis catus	92.83	0.00e+00	2278.00
IUUC-Fal-037340	Ficedula albicollis	79.04	0.00e+00	1978.00
IUUC-Gga-040595	Gallus gallus	73.50	0.00e+00	1810.00
IUUC-Ggo-045356	Gorilla gorilla	84.90	0.00e+00	2134.00
IUUC-Hsa-046135	Homo sapiens	84.76	0.00e+00	2132.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	79.37	0.00e+00	1895.00
IUUC-Lch-050183	Latimeria chalumnae	76.65	0.00e+00	1080.00
IUUC-Loc-052049	Lepisosteus oculatus	77.64	0.00e+00	1974.00
IUUC-Laf-053728	Loxodonta africana	92.37	0.00e+00	2303.00
IUUC-Mcc-054971	Macaca mulatta	85.75	0.00e+00	2149.00
IUUC-Meu-056446	Macropus eugenii	82.79	0.00e+00	2088.00
IUUC-Mga-059296	Meleagris gallopavo	78.26	0.00e+00	2027.00
IUUC-Mmr-061232	Microcebus murinus	88.55	0.00e+00	2183.00
IUUC-Mdo-062115	Monodelphis domestica	90.53	0.00e+00	2238.00
IUUC-Mmu-063664	Mus musculus	90.43	0.00e+00	2277.00
IUUC-Mlu-068238	Myotis lucifugus	88.43	0.00e+00	2198.00
IUUC-Nle-069003	Nomascus leucogenys	84.81	0.00e+00	2051.00
IUUC-Ont-072080	Oreochromis niloticus	72.73	0.00e+00	1864.00
IUUC-Oan-072891	Ornithorhynchus anatinus	73.74	0.00e+00	816.00
IUUC-Ocu-074262	Oryctolagus cuniculus	89.64	0.00e+00	2194.00
IUUC-Ola-086538	Oryzias latipes	69.56	0.00e+00	1756.00
IUUC-Oga-088722	Otolemur garnettii	87.63	0.00e+00	2152.00
IUUC-Oar-089249	Ovis aries	86.33	0.00e+00	2115.00
IUUC-Ptr-090752	Pan troglodytes	87.58	0.00e+00	1972.00
IUUC-Pan-092472	Papio anubis	88.66	0.00e+00	2173.00
IUUC-Psi-093335	Pelodiscus sinensis	82.50	0.00e+00	2066.00
IUUC-Pma-094520	Petromyzon marinus	65.97	0.00e+00	1377.00
IUUC-Ppa-095600	Physcomitrella patens	61.95	8.00e-41	159.00
IUUC-Pfo-096526	Poecilia formosa	69.03	0.00e+00	1716.00
IUUC-Pab-098428	Pongo abelii	76.71	0.00e+00	1109.00
IUUC-Pca-100233	Procavia capensis	65.35	0.00e+00	873.00
IUUC-Pva-103064	Pteropus vampyrus	79.67	0.00e+00	1909.00
IUUC-Rno-105764	Rattus norvegicus	91.00	0.00e+00	2269.00
IUUC-Sha-106649	Sarcophilus harrisii	90.36	0.00e+00	2235.00
IUUC-Smo-109478	Selaginella moellendorffii	36.68	0.00e+00	653.00
IUUC-Tgu-116870	Taeniopygia guttata	80.00	0.00e+00	1962.00
IUUC-Tru-118661	Takifugu rubripes	67.79	0.00e+00	1727.00
IUUC-Tsy-119640	Tarsius syrichta	65.90	5.00e-158	552.00
IUUC-Tni-120812	Tetraodon nigroviridis	69.14	0.00e+00	1739.00
IUUC-Ttr-128862	Tursiops truncatus	89.02	0.00e+00	2249.00
IUUC-Vpa-130049	Vicugna pacos	87.16	2.00e-159	556.00
IUUC-Xtr-131914	Xenopus tropicalis	76.09	0.00e+00	1915.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence