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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018591
Ensembl Protein ID ZK520.3a
UniProt Accession G5ECZ4; G5EDS4; DYF2_CAEEL
Genbank Protein ID ABC42046.1; CAL49447.1; CAL49448.1
Protein Name WD repeat-containing protein dyf-2; Abnormal dye filling protein 2
Genbank Nucleotide ID DQ314286; BX284603; BX284603
Gene Name dyf-2; ZK520.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00001118 ZK520.3a ZK520.3a
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.40e-08 34.3 161 187
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sdtllvsGsdDgtikv 27
           H+ svt +   ++++++s+sdD+t+ v
   Q: 161  HQRSVTQITVtPEDYVISCSDDNTLSV 187
           999*****99988***********975 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Ciliary transport protein that moves along the ciliary axoneme and that is involved in the assembly, localization and the movement of other intraflagellar transport (IFT) proteins along the cilia axoneme (PubMed:16957054, PubMed:22922713). May also associate with the BBSome complex in order to mediate ciliary transport (PubMed:22922713). Regulates cilia biogenesis, morphology and sensitivity to environmental cues (PubMed:16957054, PubMed:22922713).
 Ciliary transport protein that moves along the ciliary axoneme and that is involved in the assembly, localization and the movement of other intraflagellar transport (IFT) proteins along the cilia axoneme (PubMed:16957054, PubMed:22922713). May also associate with the BBSome complex in order to mediate ciliary transport (PubMed:22922713). Regulates cilia biogenesis, morphology and sensitivity to environmental cues (PubMed:16957054, PubMed:22922713).
Protein Sequence
(Fasta)
MSLKVIPCTL TKNQEVFKCV SAQLQYRRGE EEHGSGPIIH RWRPNGHTVA VACANNTVIY 60
YDKKGNVIDA LNPTGKLIDI AWDKEGDVLA IAVANTGTIY LWDVNSRNTD TVESGATSSK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018591|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCATTAA AGGTAATTCC GTGTACTCTC ACAAAAAATC AGGAAGTATT TAAATGTGTT 60
TCTGCTCAGC TTCAATATCG AAGAGGCGAA GAAGAGCACG GAAGTGGACC GATTATTCAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018591|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0966--Cell projection
KW-0969--Cilium
KW-0970--Cilium biogenesis/degradation
KW-0181--Complete proteome
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0097730--C:non-motile cilium
GO:0007635--P:chemosensory behavior
GO:0006935--P:chemotaxis
GO:0060271--P:cilium assembly
GO:0035721--P:intraciliary retrograde transport
GO:0042073--P:intraciliary transport
GO:1905515--P:non-motile cilium assembly
GO:0042048--P:olfactory behavior
GO:0008104--P:protein localization
KEGG cel:CELE_ZK520.3
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001534 Ailuropoda melanoleuca 22.79 9.00e-09 55.50
IUUC-Aca-004856 Anolis carolinensis 22.40 8.00e-09 55.50
IUUC-Bta-013342 Bos taurus 21.80 8.00e-08 52.40
IUUC-Cpo-021608 Cavia porcellus 39.40 0.00e+00 997.00
IUUC-Cre-022796 Chlamydomonas reinhardtii 22.27 9.00e-09 55.50
IUUC-Csa-023417 Chlorocebus sabaeus 22.37 6.00e-08 52.80
IUUC-Cho-024397 Choloepus hoffmanni 34.78 3.00e-04 40.40
IUUC-Dre-028191 Danio rerio 40.43 0.00e+00 1036.00
IUUC-Dme-031961 Drosophila melanogaster 33.04 0.00e+00 763.00
IUUC-Eca-033444 Equus caballus 21.72 6.00e-08 52.40
IUUC-Fca-036025 Felis catus 22.08 2.00e-08 54.30
IUUC-Gmo-039202 Gadus morhua 45.16 2.00e-161 562.00
IUUC-Gac-041476 Gasterosteus aculeatus 37.98 0.00e+00 964.00
IUUC-Lch-049609 Latimeria chalumnae 38.60 1.00e-81 295.00
IUUC-Loc-052919 Lepisosteus oculatus 39.88 0.00e+00 1031.00
IUUC-Mga-060030 Meleagris gallopavo 39.31 0.00e+00 1004.00
IUUC-Mpu-066840 Mustela putorius furo 39.76 0.00e+00 991.00
IUUC-Mlu-067077 Myotis lucifugus 22.88 5.00e-09 56.20
IUUC-Ont-072303 Oreochromis niloticus 24.42 2.00e-07 50.40
IUUC-Oan-073422 Ornithorhynchus anatinus 34.71 2.00e-77 281.00
IUUC-Ocu-073906 Oryctolagus cuniculus 39.20 0.00e+00 992.00
IUUC-Ola-086596 Oryzias latipes 38.73 0.00e+00 968.00
IUUC-Ptr-090583 Pan troglodytes 21.30 2.00e-07 50.80
IUUC-Pan-092689 Papio anubis 22.37 4.00e-08 53.10
IUUC-Psi-093824 Pelodiscus sinensis 23.11 2.00e-08 54.30
IUUC-Pma-094497 Petromyzon marinus 22.78 7.00e-06 45.80
IUUC-Pva-102236 Pteropus vampyrus 23.28 2.00e-08 53.90
IUUC-Rno-105208 Rattus norvegicus 39.39 0.00e+00 999.00
IUUC-Sha-107068 Sarcophilus harrisii 39.38 0.00e+00 1005.00
IUUC-Tru-118007 Takifugu rubripes 25.35 4.00e-09 56.60
Created Date 25-Jun-2017

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