iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRNAMap
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-06	28.7	274	307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d  t++a+ ++ +  ++++ D+ ik+ Dl++ +
   Q: 274  HKDNLTSVALsQTlNKAATCG-DNCIKIHDLTELR 307
           9*********87789999988.89******99766 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKRVFSLLEK TWLGAPIQFA WQKSSGNYLA VTGADSVVKI FDRHGQKRSE ISLPGNCVAM 60
DWDKDGDILA VIAEKSSCIY LWDANTNKTS QLDNGMRDQM SFLLWSKIGS FLAVGTIKGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAGTTCT GTTGCGCCTG CGCACTTCCA AGATCGGGGT TGCCGCTGGA GCCTTGAAAT 60
GAAGGTAAAT AACTTACAAA TGCCCGCGGG ATGAGAAGAC GCGGACCACC TCTGTATTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005929--C:cilium
GO:0030991--C:intraciliary transport particle A
GO:0031514--C:motile cilium
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0000902--P:cell morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271--P:cilium assembly
GO:0055123--P:digestive system development
GO:0042471--P:ear morphogenesis
GO:0031076--P:embryonic camera-type eye development
GO:0048701--P:embryonic cranial skeleton morphogenesis
GO:0030326--P:embryonic limb morphogenesis
GO:0008406--P:gonad development
GO:0001701--P:in utero embryonic development
GO:0035721--P:intraciliary retrograde transport
GO:0061055--P:myotome development
GO:0050877--P:neurological system process
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

KEGG

rno:305349

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018591	Caenorhabditis elegans	39.26	0.00e+00	1011.00
IUUC-Cpo-021608	Cavia porcellus	89.38	0.00e+00	2491.00
IUUC-Cre-022796	Chlamydomonas reinhardtii	22.18	1.00e-13	72.80
IUUC-Dre-028191	Danio rerio	77.27	0.00e+00	2179.00
IUUC-Dme-031961	Drosophila melanogaster	40.60	0.00e+00	1055.00
IUUC-Gmo-039202	Gadus morhua	78.43	0.00e+00	1022.00
IUUC-Gac-041476	Gasterosteus aculeatus	66.55	0.00e+00	1928.00
IUUC-Lch-049609	Latimeria chalumnae	75.96	0.00e+00	692.00
IUUC-Loc-052919	Lepisosteus oculatus	79.10	0.00e+00	2272.00
IUUC-Mga-060030	Meleagris gallopavo	81.66	0.00e+00	2338.00
IUUC-Mpu-066840	Mustela putorius furo	92.17	0.00e+00	2543.00
IUUC-Oan-073422	Ornithorhynchus anatinus	73.32	0.00e+00	738.00
IUUC-Ocu-073906	Oryctolagus cuniculus	90.08	0.00e+00	2520.00
IUUC-Ola-086596	Oryzias latipes	67.31	0.00e+00	1911.00
IUUC-Pma-094497	Petromyzon marinus	21.68	4.00e-08	54.70
IUUC-Sha-107068	Sarcophilus harrisii	81.19	0.00e+00	2308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence