iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-16	60.1	16	45

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H d ++c++f +  +++++++ D t+ +WD
   Q: 16   HRDLIHCVSFdPHgRRMATCASDMTMAIWD 45
           9*********977799************** PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus.

Protein Sequence
(Fasta)

MQEDDSVKPF QTVGAHRDLI HCVSFDPHGR RMATCASDMT MAIWDRKPDG NWRRSAHWKC 60
HGGAVWRVIW AHPEFGQIVA TCSYDRTIVI WEEQIVRSEK DLKQKESQWI RRTIISDNRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAATGCAA GAAGACGACT CGGTGAAACC TTTTCAGACC GTCGGCGCTC ACAGAGATCT 60
CATTCATTGT GTATGTTGGC TTGATTTCGA AAAATTAGAT AAAAACTGAA GATTTTTATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005643--C:nuclear pore
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport

KEGG

cel:CELE_Y43F4B.4

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001926	Ailuropoda melanoleuca	42.12	2.00e-71	261.00
IUUC-Apl-003654	Anas platyrhynchos	39.79	2.00e-60	224.00
IUUC-Aca-004378	Anolis carolinensis	39.79	2.00e-60	224.00
IUUC-Ago-007816	Ashbya gossypii	29.03	1.00e-28	119.00
IUUC-Ame-011945	Astyanax mexicanus	40.84	2.00e-68	251.00
IUUC-Bta-013306	Bos taurus	41.80	2.00e-71	261.00
IUUC-Cja-018849	Callithrix jacchus	42.31	4.00e-71	260.00
IUUC-Cfa-020841	Canis familiaris	41.75	4.00e-71	263.00
IUUC-Cpo-021379	Cavia porcellus	41.48	6.00e-71	259.00
IUUC-Csa-023900	Chlorocebus sabaeus	41.80	2.00e-71	261.00
IUUC-Cho-024660	Choloepus hoffmanni	39.08	2.00e-59	221.00
IUUC-Cin-025471	Ciona intestinalis	38.21	5.00e-67	246.00
IUUC-Csv-026242	Ciona savignyi	42.15	4.00e-61	226.00
IUUC-Dre-028068	Danio rerio	40.71	9.00e-72	262.00
IUUC-Dno-029981	Dasypus novemcinctus	39.68	3.00e-67	248.00
IUUC-Dme-031763	Drosophila melanogaster	38.34	5.00e-64	236.00
IUUC-Ete-032243	Echinops telfairi	50.00	2.00e-22	98.60
IUUC-Eca-033425	Equus caballus	39.08	3.00e-59	220.00
IUUC-Eeu-035119	Erinaceus europaeus	47.62	3.00e-39	154.00
IUUC-Fca-036520	Felis catus	41.80	1.00e-71	262.00
IUUC-Fal-037234	Ficedula albicollis	39.79	1.00e-60	228.00
IUUC-Gmo-039013	Gadus morhua	40.51	3.00e-69	253.00
IUUC-Gga-041059	Gallus gallus	42.77	7.00e-73	266.00
IUUC-Gac-041337	Gasterosteus aculeatus	40.51	1.00e-67	248.00
IUUC-Ggo-044944	Gorilla gorilla	41.80	2.00e-71	261.00
IUUC-Hsa-046038	Homo sapiens	41.80	1.00e-71	261.00
IUUC-Itr-048858	Ictidomys tridecemlineatus	39.08	2.00e-59	221.00
IUUC-Kpa-049201	Komagataella pastoris	29.54	7.00e-35	139.00
IUUC-Lch-050466	Latimeria chalumnae	35.93	2.00e-63	234.00
IUUC-Loc-052773	Lepisosteus oculatus	36.09	1.00e-63	235.00
IUUC-Laf-053409	Loxodonta africana	42.12	7.00e-72	262.00
IUUC-Meu-055958	Macropus eugenii	30.28	1.00e-27	115.00
IUUC-Mga-059348	Meleagris gallopavo	39.79	1.00e-60	224.00
IUUC-Mmr-060977	Microcebus murinus	46.58	3.00e-61	226.00
IUUC-Mdo-061806	Monodelphis domestica	42.77	1.00e-72	265.00
IUUC-Mmu-064328	Mus musculus	42.31	1.00e-74	272.00
IUUC-Mpu-066873	Mustela putorius furo	41.80	3.00e-71	261.00
IUUC-Mlu-067563	Myotis lucifugus	42.43	5.00e-70	256.00
IUUC-Nle-068977	Nomascus leucogenys	39.66	1.00e-63	235.00
IUUC-Opr-070773	Ochotona princeps	40.71	2.00e-20	91.70
IUUC-Ont-072644	Oreochromis niloticus	39.87	1.00e-67	248.00
IUUC-Oan-073098	Ornithorhynchus anatinus	39.79	6.00e-60	223.00
IUUC-Ocu-073911	Oryctolagus cuniculus	41.80	1.00e-71	261.00
IUUC-Ola-087096	Oryzias latipes	39.87	1.00e-66	245.00
IUUC-Oga-088798	Otolemur garnettii	41.80	1.00e-71	261.00
IUUC-Oar-090298	Ovis aries	38.81	3.00e-59	224.00
IUUC-Ptr-091074	Pan troglodytes	41.80	7.00e-72	262.00
IUUC-Pan-092013	Papio anubis	45.93	1.00e-63	234.00
IUUC-Psi-093508	Pelodiscus sinensis	40.14	3.00e-61	227.00
IUUC-Pma-094288	Petromyzon marinus	49.75	3.00e-57	213.00
IUUC-Pfo-096384	Poecilia formosa	39.87	1.00e-67	249.00
IUUC-Pab-098629	Pongo abelii	41.80	8.00e-72	262.00
IUUC-Pca-100322	Procavia capensis	43.37	2.00e-37	148.00
IUUC-Pva-102861	Pteropus vampyrus	41.80	1.00e-71	261.00
IUUC-Rno-104895	Rattus norvegicus	37.58	1.00e-65	244.00
IUUC-Sce-106420	Saccharomyces cerevisiae	26.18	3.00e-31	127.00
IUUC-Sha-106829	Sarcophilus harrisii	38.51	2.00e-62	231.00
IUUC-Sja-107923	Schizosaccharomyces japonicus	32.15	2.00e-40	158.00
IUUC-Spo-108184	Schizosaccharomyces pombe	31.16	1.00e-39	155.00
IUUC-Sar-113279	Sorex araneus	39.44	1.00e-59	221.00
IUUC-Ssc-115589	Sus scrofa	39.30	7.00e-59	219.00
IUUC-Tgu-117523	Taeniopygia guttata	42.77	6.00e-73	266.00
IUUC-Tru-117985	Takifugu rubripes	38.33	5.00e-57	216.00
IUUC-Tsy-118913	Tarsius syrichta	38.35	6.00e-51	193.00
IUUC-Tni-120670	Tetraodon nigroviridis	40.19	3.00e-68	250.00
IUUC-Tme-126885	Tuber melanosporum	29.55	1.00e-30	125.00
IUUC-Tbe-127344	Tupaia belangeri	29.90	2.00e-37	149.00
IUUC-Ttr-128347	Tursiops truncatus	39.08	2.00e-59	221.00
IUUC-Vpa-130656	Vicugna pacos	38.38	1.00e-58	219.00
IUUC-Xtr-132736	Xenopus tropicalis	42.77	1.00e-73	268.00
IUUC-Xma-133678	Xiphophorus maculatus	40.51	2.00e-68	251.00
IUUC-Yli-134659	Yarrowia lipolytica	32.53	2.00e-40	157.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence