iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011133

Ensembl Protein ID

ENSAMXP00000009783.1

UniProt Accession

W5KQC1; W5KQC1_ASTMX

Genbank Protein ID

ENSAMXP00000009783

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

APWO01112831

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000009522.1	ENSAMXT00000009783.1	ENSAMXP00000009783.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.80e-10	38.9	198	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 198  TYC-LCHQVSYGE--MIGCDNtdCSiEWFHFACVGLT---TKPRGK-WYCPRCSQ 245
           69*.*******99..*****999999***********...899996.******97 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKG QIDSLAREYT ANARTLSSDQ 60
KLSLLRQIQQ SYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGCGGG GTCGTGGCCG CGCTCGCCCC CTACAGAGAC CACCACACAC CACCACCATA 60
CTCCATACTC CAGTCCACAC TCCACACTGC CTGTGCTCTT CTTCGAGATG GCGGCTGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	79.68	1.00e-108	385.00
IUUC-Atr-002906	Amborella trichopoda	34.52	5.00e-36	144.00
IUUC-Apl-004097	Anas platyrhynchos	80.00	1.00e-108	385.00
IUUC-Aca-004593	Anolis carolinensis	83.27	2.00e-114	404.00
IUUC-Ath-006578	Arabidopsis thaliana	33.33	2.00e-33	135.00
IUUC-Bta-012699	Bos taurus	82.47	4.00e-110	390.00
IUUC-Bdi-014504	Brachypodium distachyon	35.38	8.00e-40	156.00
IUUC-Bol-015751	Brassica oleracea	33.58	2.00e-34	138.00
IUUC-Cel-018700	Caenorhabditis elegans	45.45	3.00e-07	50.80
IUUC-Cja-019988	Callithrix jacchus	81.67	7.00e-103	366.00
IUUC-Cfa-021282	Canis familiaris	81.67	7.00e-103	366.00
IUUC-Cpo-022011	Cavia porcellus	82.07	7.00e-111	392.00
IUUC-Csa-023203	Chlorocebus sabaeus	81.67	7.00e-103	366.00
IUUC-Cin-025479	Ciona intestinalis	59.58	1.00e-78	285.00
IUUC-Csv-026288	Ciona savignyi	55.11	3.00e-75	274.00
IUUC-Dre-028264	Danio rerio	95.60	7.00e-145	505.00
IUUC-Dno-029766	Dasypus novemcinctus	78.40	1.00e-95	342.00
IUUC-Dor-031136	Dipodomys ordii	70.17	8.00e-83	299.00
IUUC-Eca-033565	Equus caballus	81.67	3.00e-110	390.00
IUUC-Eeu-034948	Erinaceus europaeus	69.35	7.00e-91	326.00
IUUC-Fca-036368	Felis catus	81.67	6.00e-103	366.00
IUUC-Fal-037120	Ficedula albicollis	79.60	2.00e-107	381.00
IUUC-Gmo-038982	Gadus morhua	89.64	4.00e-134	470.00
IUUC-Gga-040771	Gallus gallus	83.27	2.00e-114	404.00
IUUC-Gac-042184	Gasterosteus aculeatus	89.02	3.00e-131	460.00
IUUC-Gma-044339	Glycine max	32.30	7.00e-34	137.00
IUUC-Ggo-045559	Gorilla gorilla	81.67	7.00e-103	366.00
IUUC-Hsa-046852	Homo sapiens	81.67	7.00e-103	366.00
IUUC-Hvu-047046	Hordeum vulgare	33.20	2.00e-37	149.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	82.07	1.00e-110	392.00
IUUC-Lpe-050822	Leersia perrieri	36.15	2.00e-39	155.00
IUUC-Loc-052334	Lepisosteus oculatus	73.91	6.00e-107	380.00
IUUC-Laf-054057	Loxodonta africana	81.67	6.00e-103	366.00
IUUC-Mcc-055212	Macaca mulatta	78.88	6.00e-103	366.00
IUUC-Meu-056511	Macropus eugenii	80.25	4.00e-101	360.00
IUUC-Mga-059967	Meleagris gallopavo	80.72	7.00e-108	382.00
IUUC-Mmr-060843	Microcebus murinus	80.88	3.00e-109	387.00
IUUC-Mdo-062357	Monodelphis domestica	80.88	1.00e-109	388.00
IUUC-Mmu-064093	Mus musculus	82.07	7.00e-111	392.00
IUUC-Mpu-066923	Mustela putorius furo	70.92	7.00e-81	293.00
IUUC-Mlu-067754	Myotis lucifugus	79.13	1.00e-108	385.00
IUUC-Nle-069062	Nomascus leucogenys	81.67	7.00e-103	366.00
IUUC-Opr-070207	Ochotona princeps	76.47	4.00e-95	340.00
IUUC-Ont-072446	Oreochromis niloticus	89.60	6.00e-126	442.00
IUUC-Ocu-074235	Oryctolagus cuniculus	81.67	7.00e-103	366.00
IUUC-Obr-076266	Oryza brachyantha	35.77	4.00e-39	154.00
IUUC-Ogl-077118	Oryza glaberrima	35.77	3.00e-39	154.00
IUUC-Oin-079049	Oryza indica	36.15	2.00e-38	152.00
IUUC-Ome-081291	Oryza meridionalis	35.77	4.00e-38	150.00
IUUC-Oni-082218	Oryza nivara	36.15	2.00e-38	152.00
IUUC-Opu-084171	Oryza punctata	36.36	1.00e-37	149.00
IUUC-Osa-085563	Oryza sativa	35.77	4.00e-38	150.00
IUUC-Ola-086429	Oryzias latipes	85.60	4.00e-126	443.00
IUUC-Oga-089123	Otolemur garnettii	81.67	6.00e-103	366.00
IUUC-Oar-089524	Ovis aries	82.47	4.00e-110	390.00
IUUC-Ptr-090908	Pan troglodytes	81.27	2.00e-102	364.00
IUUC-Pan-092837	Papio anubis	79.68	1.00e-108	385.00
IUUC-Psi-093828	Pelodiscus sinensis	82.13	1.00e-103	368.00
IUUC-Ppa-096009	Physcomitrella patens	35.04	4.00e-36	144.00
IUUC-Pfo-096617	Poecilia formosa	90.40	3.00e-135	473.00
IUUC-Pab-097978	Pongo abelii	80.25	5.00e-92	330.00
IUUC-Pop-099415	Populus trichocarpa	73.68	8.00e-26	110.00
IUUC-Pca-100475	Procavia capensis	54.40	5.00e-72	263.00
IUUC-Ppe-101441	Prunus persica	35.41	5.00e-38	150.00
IUUC-Pva-102325	Pteropus vampyrus	81.67	3.00e-110	390.00
IUUC-Rno-105178	Rattus norvegicus	82.07	3.00e-118	417.00
IUUC-Sha-106773	Sarcophilus harrisii	80.88	1.00e-109	389.00
IUUC-Sit-109827	Setaria italica	33.85	1.00e-36	145.00
IUUC-Sly-111750	Solanum lycopersicum	34.90	4.00e-34	137.00
IUUC-Stu-112250	Solanum tuberosum	34.90	4.00e-34	137.00
IUUC-Sre-115124	Sporisorium reilianum	59.32	9.00e-22	98.60
IUUC-Ssc-115797	Sus scrofa	77.33	7.00e-92	329.00
IUUC-Tgu-117270	Taeniopygia guttata	83.27	2.00e-114	404.00
IUUC-Tru-118253	Takifugu rubripes	88.49	1.00e-133	468.00
IUUC-Tca-121597	Theobroma cacao	35.41	6.00e-34	137.00
IUUC-Tbe-127558	Tupaia belangeri	79.68	1.00e-108	385.00
IUUC-Ttr-128300	Tursiops truncatus	79.28	6.00e-52	197.00
IUUC-Uma-129581	Ustilago maydis	59.32	1.00e-21	98.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence