iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000018482.3	ENSMMUT00000076135.1	ENSMMUP00000053767.1
ENSMMUG00000018482.3	ENSMMUT00000068424.1	ENSMMUP00000049189.1
ENSMMUG00000018482.3	ENSMMUT00000066136.1	ENSMMUP00000058150.1
ENSMMUG00000018482.3	ENSMMUT00000055729.1	ENSMMUP00000049742.1
ENSMMUG00000018482.3	ENSMMUT00000073163.1	ENSMMUP00000059993.1
ENSMMUG00000018482.3	ENSMMUT00000025988.3	ENSMMUP00000024317.3
ENSMMUG00000018482.3	ENSMMUT00000054455.1	ENSMMUP00000052697.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.70e-37	127.7	37	177

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l ke++ele++ p ++++++ d ++l+ ++++++ p++ +Y+gg+F++e e+p+ Y++ PPkvk+ltki+hPn++e+G++Cls+l+   
   Q: 37   LVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVT-PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLRehs 124
           679********************99*********.**************************************************7778 PP
   S: 88   .eeekWspalsvesvllsiqsllae.pnpesplneeaaellkknreeykkkvr 138
            + + W p+ ++++v+++++sl+++  n+++pln eaae++ +++e++++kv+
   Q: 125  iDGTGWAPTRTLKDVVWGLNSLFTDlLNFDDPLNIEAAEHHLRDKEDFRNKVD 177
           8899*******************8879***********************995 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN 60
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTTGG GCGCCGGACC CGCCTCGCCT GTCTCGGGGA GCCCAGGTGA GGAGCGACCG 60
CGCGGCTCTG CGGCGGGGCG AGGTGCGGAA ACCGGTGCAC AGGCTGGCCT GCGGGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

KEGG

mcc:695394

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001473	Ailuropoda melanoleuca	97.30	2.00e-93	334.00
IUUC-Apl-003569	Anas platyrhynchos	85.71	3.00e-48	182.00
IUUC-Aca-005152	Anolis carolinensis	90.81	2.00e-98	351.00
IUUC-Ame-011839	Astyanax mexicanus	80.00	4.00e-89	320.00
IUUC-Bta-013524	Bos taurus	97.30	6.00e-94	335.00
IUUC-Bci-013626	Botrytis cinerea	41.03	8.00e-28	116.00
IUUC-Cel-018579	Caenorhabditis elegans	58.27	1.00e-35	142.00
IUUC-Cja-019211	Callithrix jacchus	99.46	4.00e-97	346.00
IUUC-Cfa-020014	Canis familiaris	97.30	2.00e-93	334.00
IUUC-Cpo-022479	Cavia porcellus	99.46	4.00e-97	346.00
IUUC-Cho-024583	Choloepus hoffmanni	67.57	4.00e-63	233.00
IUUC-Cin-025378	Ciona intestinalis	50.00	7.00e-53	199.00
IUUC-Csv-026195	Ciona savignyi	51.37	8.00e-51	192.00
IUUC-Dre-028671	Danio rerio	82.16	6.00e-91	326.00
IUUC-Dno-029004	Dasypus novemcinctus	98.92	2.00e-108	384.00
IUUC-Dor-030940	Dipodomys ordii	97.84	4.00e-96	343.00
IUUC-Eca-034345	Equus caballus	97.84	6.00e-94	335.00
IUUC-Fca-036125	Felis catus	97.30	2.00e-93	334.00
IUUC-Fal-036808	Ficedula albicollis	92.43	1.00e-101	361.00
IUUC-Gmo-039394	Gadus morhua	90.27	8.00e-61	224.00
IUUC-Gga-041269	Gallus gallus	88.17	2.00e-94	338.00
IUUC-Gac-041480	Gasterosteus aculeatus	82.70	2.00e-89	320.00
IUUC-Ggo-045010	Gorilla gorilla	100.00	4.00e-109	386.00
IUUC-Hsa-046664	Homo sapiens	100.00	4.00e-109	386.00
IUUC-Itr-048522	Ictidomys tridecemlineatus	97.30	8.00e-96	342.00
IUUC-Kpa-049315	Komagataella pastoris	43.94	2.00e-24	105.00
IUUC-Loc-052137	Lepisosteus oculatus	84.32	2.00e-92	330.00
IUUC-Laf-053694	Loxodonta africana	95.68	3.00e-97	347.00
IUUC-Meu-056568	Macropus eugenii	77.84	7.00e-81	292.00
IUUC-Mga-059437	Meleagris gallopavo	93.51	5.00e-102	362.00
IUUC-Mmr-060651	Microcebus murinus	95.00	9.00e-91	325.00
IUUC-Mdo-061993	Monodelphis domestica	93.51	1.00e-101	362.00
IUUC-Mmu-064372	Mus musculus	96.76	8.00e-96	342.00
IUUC-Mpu-066423	Mustela putorius furo	96.76	3.00e-93	333.00
IUUC-Mlu-067910	Myotis lucifugus	96.76	3.00e-93	333.00
IUUC-Nle-069032	Nomascus leucogenys	99.46	4.00e-97	346.00
IUUC-Opr-070798	Ochotona princeps	98.38	2.00e-107	380.00
IUUC-Ont-071232	Oreochromis niloticus	83.24	3.00e-90	323.00
IUUC-Oan-072779	Ornithorhynchus anatinus	92.56	5.00e-66	242.00
IUUC-Ocu-074366	Oryctolagus cuniculus	94.05	3.00e-104	370.00
IUUC-Ola-087548	Oryzias latipes	88.14	9.00e-62	228.00
IUUC-Oga-089149	Otolemur garnettii	99.46	3.00e-99	353.00
IUUC-Oar-089662	Ovis aries	97.30	6.00e-94	335.00
IUUC-Ptr-090895	Pan troglodytes	100.00	4.00e-109	386.00
IUUC-Pan-092771	Papio anubis	99.46	1.00e-107	381.00
IUUC-Psi-093582	Pelodiscus sinensis	92.43	2.00e-101	360.00
IUUC-Pma-094321	Petromyzon marinus	84.96	3.00e-67	246.00
IUUC-Pfo-096040	Poecilia formosa	84.32	2.00e-91	327.00
IUUC-Pab-097931	Pongo abelii	100.00	4.00e-109	386.00
IUUC-Pca-100697	Procavia capensis	96.55	3.00e-84	303.00
IUUC-Pva-102609	Pteropus vampyrus	96.22	2.00e-94	337.00
IUUC-Rno-105622	Rattus norvegicus	96.22	8.00e-96	342.00
IUUC-Sha-107614	Sarcophilus harrisii	92.47	2.00e-100	357.00
IUUC-Ssl-108427	Sclerotinia sclerotiorum	41.03	9.00e-28	116.00
IUUC-Ssc-115597	Sus scrofa	95.14	2.00e-95	341.00
IUUC-Tgu-117397	Taeniopygia guttata	92.97	4.00e-102	363.00
IUUC-Tru-118496	Takifugu rubripes	81.62	5.00e-88	316.00
IUUC-Tsy-119592	Tarsius syrichta	98.92	6.00e-99	352.00
IUUC-Tni-119759	Tetraodon nigroviridis	81.62	3.00e-88	317.00
IUUC-Tbe-128085	Tupaia belangeri	81.48	1.00e-61	228.00
IUUC-Ttr-129228	Tursiops truncatus	96.22	4.00e-93	333.00
IUUC-Xtr-131773	Xenopus tropicalis	90.51	6.00e-62	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence