iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062506

UUCD1 version

UUC-MoD-01144

Ensembl Protein ID

ENSMODP00000019999.3

UniProt Accession

F7EFT6; F7EFT6_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016025.3	ENSMODT00000020356.3	ENSMODP00000019999.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.70e-73	245.9	89	419
ULD/UDP/UBQ/UBQ_Other	3.70e-10	39.7	946	1008

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenp........kepkgellkslqklfeelwkskkkavsprel 73
           +Gl+Nlg+tCY+N  LQ+ +   elr++l                             + + ++++++lq lf+ l++s++++++p+ +
   Q: 89   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstcgdhM---------MgdgiqeekDYEPQTICEHLQYLFALLQNSNRRYIDPSGF 168
           6*****************************9555555533.........33333333377888************************** PP
   S: 74   lkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnv 162
           +kal+     +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++
   Q: 169  VKALG-----LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRE 229
           ****9.....78899*******************.......................457889999*********************** PP
   S: 163  ssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekink 251
           s+  ++f++l+l+++g++     +l+dc+ +f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+
   Q: 230  SKLLSKFYELELNIQGHK-----QLTDCITEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNT 313
           ******************.....9***************************************************************** PP
   S: 252  kvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg........... 327
           ++ f + Ld++p+++++e      + YeL+av++H G s+ sGHY+a+vk+ + + W++f+D+ +++++ ++ +   +           
   Q: 314  YIGFSELLDMEPYMEHKEG----IYVYELSAVLIHRGvSAYSGHYIAHVKDPQTGeWYKFNDEDIEKMEGKKLQLGIEedlaepsksqt 398
           *****99*******99553....89**************************55555************9999998665999******** PP
   S: 328  ............staYvlfYk 336
                       ++aY+l+Y+
   Q: 399  rkpkcgkgthcsRNAYMLVYR 419
           ********************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++Gk+L +d  tL+ +g+ ++s+i+l  +++
   Q: 946  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKVLnDDTATLGTLGVIPESVILLKADEP 1008
           344489999************************************************988775 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIEA AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE 60
HVWLGEIDEN SFHNIDDPNS ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCCGC GGCTGCAGCT GGAGAAGGCC GCCTGGCGAT GGGCGGAGAC GGTGCGGCCC 60
GAGGAGGTGT CGCAGGAGCA CATCGAGGCG GCCTACCGCA TCTGGTTGGA GCCCTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100023231

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	32.29	2.00e-79	291.00
IUUC-Aml-001357	Ailuropoda melanoleuca	93.73	0.00e+00	1970.00
IUUC-Atr-002976	Amborella trichopoda	31.81	5.00e-77	283.00
IUUC-Apl-003773	Anas platyrhynchos	88.27	0.00e+00	1699.00
IUUC-Aca-004466	Anolis carolinensis	81.66	0.00e+00	872.00
IUUC-Aly-006249	Arabidopsis lyrata	29.72	3.00e-70	260.00
IUUC-Ath-006700	Arabidopsis thaliana	30.54	2.00e-79	291.00
IUUC-Ame-011554	Astyanax mexicanus	68.80	0.00e+00	1453.00
IUUC-Bta-012573	Bos taurus	92.97	0.00e+00	1969.00
IUUC-Bdi-014149	Brachypodium distachyon	32.27	2.00e-80	293.00
IUUC-Bol-016289	Brassica oleracea	31.80	4.00e-78	286.00
IUUC-Bra-017494	Brassica rapa	32.12	1.00e-81	298.00
IUUC-Cel-018662	Caenorhabditis elegans	27.94	2.00e-28	121.00
IUUC-Cja-019991	Callithrix jacchus	91.90	0.00e+00	1963.00
IUUC-Cfa-020294	Canis familiaris	93.73	0.00e+00	2003.00
IUUC-Cpo-021706	Cavia porcellus	90.62	0.00e+00	1853.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	31.25	3.00e-43	171.00
IUUC-Csa-023931	Chlorocebus sabaeus	93.24	0.00e+00	1981.00
IUUC-Cho-024566	Choloepus hoffmanni	92.06	2.00e-146	513.00
IUUC-Cin-025307	Ciona intestinalis	46.82	1.00e-75	276.00
IUUC-Csv-026006	Ciona savignyi	37.16	2.00e-150	526.00
IUUC-Cne-027065	Cryptococcus neoformans	28.24	1.00e-67	251.00
IUUC-Dre-027624	Danio rerio	69.49	0.00e+00	1485.00
IUUC-Dno-029633	Dasypus novemcinctus	94.17	0.00e+00	1285.00
IUUC-Dor-030809	Dipodomys ordii	72.74	0.00e+00	1168.00
IUUC-Ete-032818	Echinops telfairi	89.88	0.00e+00	937.00
IUUC-Eca-033692	Equus caballus	93.63	0.00e+00	1987.00
IUUC-Eeu-035185	Erinaceus europaeus	70.83	0.00e+00	738.00
IUUC-Fca-035676	Felis catus	93.04	0.00e+00	1990.00
IUUC-Fal-036913	Ficedula albicollis	87.27	0.00e+00	1836.00
IUUC-Gmo-038532	Gadus morhua	65.56	0.00e+00	1399.00
IUUC-Gga-041041	Gallus gallus	87.56	0.00e+00	1838.00
IUUC-Gac-042570	Gasterosteus aculeatus	66.54	0.00e+00	1425.00
IUUC-Gma-044136	Glycine max	27.68	2.00e-95	344.00
IUUC-Ggo-045367	Gorilla gorilla	88.63	0.00e+00	1848.00
IUUC-Hsa-046019	Homo sapiens	93.24	0.00e+00	1982.00
IUUC-Hvu-047303	Hordeum vulgare	33.21	8.00e-66	244.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	91.18	0.00e+00	1959.00
IUUC-Lch-049989	Latimeria chalumnae	76.98	0.00e+00	1646.00
IUUC-Lpe-051612	Leersia perrieri	33.73	3.00e-78	287.00
IUUC-Loc-052756	Lepisosteus oculatus	70.71	0.00e+00	1532.00
IUUC-Laf-054043	Loxodonta africana	92.22	0.00e+00	1978.00
IUUC-Mcc-054986	Macaca mulatta	91.72	0.00e+00	1962.00
IUUC-Meu-056228	Macropus eugenii	83.42	0.00e+00	904.00
IUUC-Mtr-058762	Medicago truncatula	29.39	2.00e-86	313.00
IUUC-Mga-059896	Meleagris gallopavo	86.91	0.00e+00	1732.00
IUUC-Mvi-060269	Microbotryum violaceum	36.75	7.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	93.44	0.00e+00	1985.00
IUUC-Mmu-063642	Mus musculus	88.71	0.00e+00	1910.00
IUUC-Mac-064896	Musa acuminata	32.33	2.00e-75	277.00
IUUC-Mpu-066194	Mustela putorius furo	93.63	0.00e+00	1982.00
IUUC-Mlu-067233	Myotis lucifugus	92.63	0.00e+00	1975.00
IUUC-Nle-069052	Nomascus leucogenys	92.18	0.00e+00	1966.00
IUUC-Opr-070890	Ochotona princeps	91.75	0.00e+00	1212.00
IUUC-Ont-071450	Oreochromis niloticus	65.62	0.00e+00	1387.00
IUUC-Oan-073252	Ornithorhynchus anatinus	91.62	0.00e+00	1060.00
IUUC-Ocu-073796	Oryctolagus cuniculus	92.08	0.00e+00	1699.00
IUUC-Oba-075563	Oryza barthii	33.39	2.00e-80	293.00
IUUC-Obr-076394	Oryza brachyantha	32.66	2.00e-80	294.00
IUUC-Ogl-077339	Oryza glaberrima	38.78	4.00e-41	161.00
IUUC-Ogu-079007	Oryza glumaepatula	32.99	1.00e-74	275.00
IUUC-Oin-079997	Oryza indica	33.39	1.00e-80	295.00
IUUC-Olo-080364	Oryza longistaminata	33.39	2.00e-80	294.00
IUUC-Ome-081165	Oryza meridionalis	32.99	3.00e-75	276.00
IUUC-Oni-083026	Oryza nivara	33.39	1.00e-80	295.00
IUUC-Opu-083284	Oryza punctata	33.80	2.00e-74	274.00
IUUC-Oru-084797	Oryza rufipogon	33.39	2.00e-80	294.00
IUUC-Osa-086221	Oryza sativa	38.78	4.00e-41	161.00
IUUC-Ola-086568	Oryzias latipes	67.07	0.00e+00	1437.00
IUUC-Oga-088687	Otolemur garnettii	92.18	0.00e+00	1962.00
IUUC-Oar-090345	Ovis aries	93.06	0.00e+00	1877.00
IUUC-Ptr-090734	Pan troglodytes	93.24	0.00e+00	1981.00
IUUC-Pan-091704	Papio anubis	89.71	0.00e+00	1886.00
IUUC-Psi-092937	Pelodiscus sinensis	87.99	0.00e+00	1622.00
IUUC-Ppa-095808	Physcomitrella patens	28.59	9.00e-69	255.00
IUUC-Pab-098129	Pongo abelii	93.24	0.00e+00	1982.00
IUUC-Pop-099738	Populus trichocarpa	31.88	3.00e-77	283.00
IUUC-Pca-100647	Procavia capensis	96.36	0.00e+00	679.00
IUUC-Ppe-102091	Prunus persica	30.80	2.00e-82	300.00
IUUC-Pva-102719	Pteropus vampyrus	92.76	0.00e+00	1965.00
IUUC-Rno-105363	Rattus norvegicus	90.25	0.00e+00	1933.00
IUUC-Sha-107620	Sarcophilus harrisii	94.78	0.00e+00	1921.00
IUUC-Smo-109487	Selaginella moellendorffii	27.41	5.00e-81	296.00
IUUC-Sit-110683	Setaria italica	28.96	2.00e-79	290.00
IUUC-Sly-111377	Solanum lycopersicum	31.51	3.00e-81	297.00
IUUC-Stu-111969	Solanum tuberosum	31.61	5.00e-71	262.00
IUUC-Sar-113099	Sorex araneus	92.20	0.00e+00	1677.00
IUUC-Sbi-113833	Sorghum bicolor	41.81	3.00e-56	211.00
IUUC-Ssc-115279	Sus scrofa	85.30	0.00e+00	1285.00
IUUC-Tgu-117519	Taeniopygia guttata	84.71	0.00e+00	1686.00
IUUC-Tru-117651	Takifugu rubripes	66.51	0.00e+00	1416.00
IUUC-Tsy-119201	Tarsius syrichta	90.01	0.00e+00	1764.00
IUUC-Tni-120840	Tetraodon nigroviridis	67.73	0.00e+00	1439.00
IUUC-Tca-121674	Theobroma cacao	30.28	5.00e-85	309.00
IUUC-Tae-125247	Triticum aestivum	28.39	1.00e-79	291.00
IUUC-Tur-126599	Triticum urartu	32.65	2.00e-78	288.00
IUUC-Tbe-127782	Tupaia belangeri	82.90	0.00e+00	1687.00
IUUC-Ttr-128312	Tursiops truncatus	92.08	0.00e+00	1947.00
IUUC-Vpa-130348	Vicugna pacos	92.94	0.00e+00	1880.00
IUUC-Vvi-131353	Vitis vinifera	32.10	7.00e-84	305.00
IUUC-Xtr-132172	Xenopus tropicalis	70.26	0.00e+00	1340.00
IUUC-Xma-133263	Xiphophorus maculatus	67.55	0.00e+00	1400.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence