iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csv-025976

Ensembl Protein ID

ENSCSAVP00000008109.1

UniProt Accession

H2YRZ9; H2YRZ9_CIOSA

Protein Name

Defective in cullin neddylation protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000004825.1	ENSCSAVT00000008217.1	ENSCSAVP00000008109.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/DCUN1	41.28	2.00e-33	139.00	IUUC-Ath-007531
E3 activity/DCUN1	23.83	6.00e-11	62.40	IUUC-Sce-106358
UBD/Alpha-Helix/UBA	23.83	6.00e-11	62.40	IUUC-Sce-106358

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ciona savignyi

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MPFQGKKRKW QGSEESKKIK RSRNLPTSKS QKSITDALSA SSHHKTQSKC SFNMKNCIKW 60
FKEYAENNQV EPEGMERFCK SLGVEPDDVV MLVLAHQLNA KKMGFFTIEE WSRGMQKLQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTGAAAAT TAACACAGTA GACTTCTTTT AAGAAACAGC AACGGAAGAC ATTTCAGTTC 60
TTTTTTGCAG GTGAGTATAT AAGTTACCGT GGTATATTTT TATTGTTGAA TTTATTGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	36.77	1.00e-34	138.00
IUUC-Aml-001567	Ailuropoda melanoleuca	56.48	3.00e-63	233.00
IUUC-Apl-003338	Anas platyrhynchos	56.48	8.00e-63	231.00
IUUC-Aca-004660	Anolis carolinensis	47.95	3.00e-64	236.00
IUUC-Aly-006285	Arabidopsis lyrata	42.58	3.00e-32	130.00
IUUC-Ath-007531	Arabidopsis thaliana	41.28	6.00e-35	139.00
IUUC-Ago-007806	Ashbya gossypii	25.52	8.00e-14	68.90
IUUC-Acl-008172	Aspergillus clavatus	27.96	1.00e-12	65.50
IUUC-Afl-008569	Aspergillus flavus	30.34	6.00e-15	72.80
IUUC-Afu-009005	Aspergillus fumigatus	28.57	6.00e-14	68.60
IUUC-Ani-009241	Aspergillus nidulans	30.48	8.00e-18	82.40
IUUC-Ang-009664	Aspergillus niger	28.65	3.00e-13	67.00
IUUC-Aor-009902	Aspergillus oryzae	28.95	6.00e-08	48.10
IUUC-Ate-010414	Aspergillus terreus	30.90	4.00e-17	79.70
IUUC-Bgr-011991	Blumeria graminis	28.38	2.00e-15	74.70
IUUC-Bta-013463	Bos taurus	56.48	3.00e-63	232.00
IUUC-Bci-013824	Botrytis cinerea	28.00	1.00e-12	65.10
IUUC-Bdi-014138	Brachypodium distachyon	36.77	3.00e-34	137.00
IUUC-Bol-015564	Brassica oleracea	36.16	4.00e-36	142.00
IUUC-Bra-017255	Brassica rapa	41.28	1.00e-35	140.00
IUUC-Cel-018441	Caenorhabditis elegans	30.89	4.00e-24	103.00
IUUC-Cja-019665	Callithrix jacchus	56.48	3.00e-63	233.00
IUUC-Cfa-020873	Canis familiaris	56.48	3.00e-63	232.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	37.63	2.00e-35	141.00
IUUC-Csa-023661	Chlorocebus sabaeus	56.48	3.00e-63	233.00
IUUC-Cin-025635	Ciona intestinalis	79.52	6.00e-79	284.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	34.08	1.00e-20	90.90
IUUC-Cne-026950	Cryptococcus neoformans	29.06	1.00e-19	88.60
IUUC-Cme-027199	Cyanidioschyzon merolae	27.97	7.00e-07	46.20
IUUC-Dre-028080	Danio rerio	49.17	2.00e-64	236.00
IUUC-Dno-029984	Dasypus novemcinctus	48.52	3.00e-62	230.00
IUUC-Dor-030556	Dipodomys ordii	56.48	3.00e-63	233.00
IUUC-Dse-031365	Dothistroma septosporum	23.98	1.00e-10	58.50
IUUC-Eca-034108	Equus caballus	56.48	3.00e-63	233.00
IUUC-Fca-035374	Felis catus	56.48	5.00e-63	232.00
IUUC-Fal-037284	Ficedula albicollis	53.77	7.00e-64	234.00
IUUC-Fox-037884	Fusarium oxysporum	33.88	5.00e-12	62.40
IUUC-Fso-038150	Fusarium solani	35.90	1.00e-13	68.90
IUUC-Ggr-039959	Gaeumannomyces graminis	27.01	2.00e-13	68.90
IUUC-Gga-040330	Gallus gallus	49.39	9.00e-64	234.00
IUUC-Gac-042443	Gasterosteus aculeatus	50.66	1.00e-61	228.00
IUUC-Gma-043545	Glycine max	33.48	5.00e-33	132.00
IUUC-Ggo-044892	Gorilla gorilla	56.48	3.00e-63	233.00
IUUC-Hsa-046320	Homo sapiens	56.48	3.00e-63	233.00
IUUC-Itr-048437	Ictidomys tridecemlineatus	56.59	4.00e-40	154.00
IUUC-Kpa-049127	Komagataella pastoris	28.92	3.00e-13	67.00
IUUC-Lch-049750	Latimeria chalumnae	50.00	4.00e-63	232.00
IUUC-Lpe-051540	Leersia perrieri	36.77	2.00e-35	140.00
IUUC-Loc-052941	Lepisosteus oculatus	57.45	3.00e-63	233.00
IUUC-Lma-053103	Leptosphaeria maculans	28.28	7.00e-14	69.30
IUUC-Laf-054402	Loxodonta africana	56.48	4.00e-63	232.00
IUUC-Mcc-055269	Macaca mulatta	56.48	3.00e-63	233.00
IUUC-Meu-056847	Macropus eugenii	54.29	1.00e-53	201.00
IUUC-Mpo-057299	Magnaporthe poae	27.36	2.00e-13	67.80
IUUC-Mtr-057964	Medicago truncatula	36.26	5.00e-33	132.00
IUUC-Mla-058990	Melampsora laricipopulina	25.47	5.00e-10	57.00
IUUC-Mga-059420	Meleagris gallopavo	55.61	3.00e-63	232.00
IUUC-Mvi-060312	Microbotryum violaceum	30.05	1.00e-24	105.00
IUUC-Mmr-061732	Microcebus murinus	56.48	3.00e-63	233.00
IUUC-Mdo-062269	Monodelphis domestica	56.48	6.00e-63	231.00
IUUC-Mmu-063396	Mus musculus	55.96	1.00e-62	231.00
IUUC-Mac-065016	Musa acuminata	37.14	1.00e-32	130.00
IUUC-Mpu-066206	Mustela putorius furo	57.40	6.00e-57	211.00
IUUC-Mlu-067871	Myotis lucifugus	48.94	5.00e-63	232.00
IUUC-Ncr-068780	Neurospora crassa	27.27	1.00e-13	68.90
IUUC-Nle-069808	Nomascus leucogenys	56.48	3.00e-63	233.00
IUUC-Ont-072416	Oreochromis niloticus	56.45	3.00e-62	229.00
IUUC-Oan-072930	Ornithorhynchus anatinus	56.32	4.00e-62	229.00
IUUC-Ocu-073767	Oryctolagus cuniculus	56.48	2.00e-63	233.00
IUUC-Oba-074993	Oryza barthii	36.77	1.00e-35	141.00
IUUC-Obr-076341	Oryza brachyantha	36.32	1.00e-35	141.00
IUUC-Ogl-077099	Oryza glaberrima	36.77	1.00e-35	141.00
IUUC-Ogu-078285	Oryza glumaepatula	36.77	2.00e-35	140.00
IUUC-Oin-079441	Oryza indica	36.77	2.00e-35	140.00
IUUC-Olo-081037	Oryza longistaminata	36.77	2.00e-35	140.00
IUUC-Ome-081357	Oryza meridionalis	36.77	2.00e-35	140.00
IUUC-Oni-082632	Oryza nivara	36.77	2.00e-35	140.00
IUUC-Opu-083351	Oryza punctata	36.77	3.00e-35	140.00
IUUC-Oru-084306	Oryza rufipogon	36.77	2.00e-35	140.00
IUUC-Osa-085307	Oryza sativa	36.77	2.00e-35	140.00
IUUC-Ola-086378	Oryzias latipes	51.34	1.00e-63	234.00
IUUC-Olu-087646	Ostreococcus lucimarinus	40.59	3.00e-36	143.00
IUUC-Oga-088583	Otolemur garnettii	56.48	3.00e-63	233.00
IUUC-Oar-089612	Ovis aries	56.48	5.00e-63	232.00
IUUC-Ptr-090753	Pan troglodytes	56.48	3.00e-63	233.00
IUUC-Pan-091951	Papio anubis	56.48	3.00e-63	233.00
IUUC-Psi-093385	Pelodiscus sinensis	55.96	1.00e-62	231.00
IUUC-Pma-094582	Petromyzon marinus	50.41	1.00e-63	234.00
IUUC-Pno-095145	Phaeosphaeria nodorum	26.09	2.00e-12	64.30
IUUC-Ppa-095771	Physcomitrella patens	41.14	7.00e-36	142.00
IUUC-Pfo-096222	Poecilia formosa	47.68	1.00e-60	224.00
IUUC-Pab-097692	Pongo abelii	56.48	3.00e-63	233.00
IUUC-Pop-098821	Populus trichocarpa	42.45	1.00e-22	96.70
IUUC-Ppe-102032	Prunus persica	37.21	4.00e-33	133.00
IUUC-Pva-102620	Pteropus vampyrus	49.13	2.00e-57	213.00
IUUC-Pgr-103633	Puccinia graminis	25.48	3.00e-16	77.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	25.47	5.00e-13	66.20
IUUC-Rno-105023	Rattus norvegicus	55.96	1.00e-62	231.00
IUUC-Sce-106358	Saccharomyces cerevisiae	23.83	7.00e-12	62.40
IUUC-Sha-107177	Sarcophilus harrisii	56.48	6.00e-63	231.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.16	2.00e-20	90.50
IUUC-Spo-108207	Schizosaccharomyces pombe	23.50	5.00e-15	72.80
IUUC-Ssl-108410	Sclerotinia sclerotiorum	29.51	4.00e-15	73.20
IUUC-Smo-108750	Selaginella moellendorffii	36.21	1.00e-26	111.00
IUUC-Sit-110613	Setaria italica	36.77	8.00e-35	138.00
IUUC-Sly-111489	Solanum lycopersicum	34.38	4.00e-35	139.00
IUUC-Stu-112517	Solanum tuberosum	37.99	3.00e-33	133.00
IUUC-Sar-113248	Sorex araneus	55.88	7.00e-65	238.00
IUUC-Sbi-114113	Sorghum bicolor	36.16	2.00e-36	144.00
IUUC-Sre-115221	Sporisorium reilianum	27.81	5.00e-13	66.60
IUUC-Ssc-116272	Sus scrofa	48.94	2.00e-63	233.00
IUUC-Tgu-116631	Taeniopygia guttata	53.02	3.00e-63	233.00
IUUC-Tsy-119350	Tarsius syrichta	56.48	4.00e-63	232.00
IUUC-Tca-121033	Theobroma cacao	33.93	5.00e-35	139.00
IUUC-Tre-121986	Trichoderma reesei	31.55	5.00e-17	79.70
IUUC-Tae-125740	Triticum aestivum	31.06	2.00e-28	117.00
IUUC-Tur-126375	Triticum urartu	28.23	2.00e-24	104.00
IUUC-Tbe-127937	Tupaia belangeri	50.41	8.00e-66	241.00
IUUC-Ttr-128784	Tursiops truncatus	40.41	5.00e-33	132.00
IUUC-Uma-129364	Ustilago maydis	30.20	3.00e-19	87.40
IUUC-Vda-129929	Verticillium dahliae	29.14	1.00e-14	72.80
IUUC-Vpa-130543	Vicugna pacos	56.48	3.00e-63	233.00
IUUC-Vvi-130834	Vitis vinifera	33.93	5.00e-35	139.00
IUUC-Xtr-132448	Xenopus tropicalis	49.38	1.00e-62	231.00
IUUC-Xma-133032	Xiphophorus maculatus	53.72	8.00e-60	221.00
IUUC-Yli-134595	Yarrowia lipolytica	27.00	4.00e-19	86.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence