iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-41	138.4	14	49
UBD/Beta-Prp	1.90e-54	185.1	7	186

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f..sd.tllvsGsdDgtikvWDlrt 32
           gHt++vt +a +  +d t+++s+s+D+ti vWD+++
   Q: 14   GHTGWVTQIAtYtrNDkTTVLSSSRDKTILVWDVDS 49
           8********967**999****************965 PP

UBD/Beta-Prp

   S: 85   kcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           k + tl+gh+  v+ ++ +   ++ +++s s+d+ti vwd+++   + e         l+gh+++v+ vv+++dg+   sGs D+t+rlWdl++g   r+
   Q: 7    KLTGTLEGHTGWVTQIATYTrnDKTTVLSSSRDKTILVWDVDSVAPVDEgpigrpvrSLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQ 106
           6677899999999999988874558899999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng..htdnvksvrfs..pnderlvsgssDgsiriWdlr 252
           + + ht++v s++f+ + +++vsgs+d+++klw+  ++ c +t ++  htd+v+ vrfs  ++d  +vs++ D+++++W+l 
   Q: 107  FIS-HTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLAQ-CKYTITDdcHTDWVSTVRFSpsNRDPVIVSAGWDKVVKVWNLG 186
           998.9999999999999999999999999999998644.6665553339999999999977788899999999999999754 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Required for the expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury.

Protein Sequence
(Fasta)

MVQEQMKLTG TLEGHTGWVT QIATYTRNDK TTVLSSSRDK TILVWDVDSV APVDEGPIGR 60
PVRSLTGHNH FVSDVVISSD GQFALSGSWD KTLRLWDLNQ GVSTRQFISH TKDVLSVAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATCGAAC GGGGTTACAC AGATAGCAAA ATGGTCCAAG AGCAAATGAA GCTTACCGGA 60
ACCCTCGAGG GTCACACCGG ATGGGTTACC CAAATCGCCA CCTACACCCG CAACGACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0689--Ribosomal protein
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030424--C:axon
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0030426--C:growth cone
GO:0000776--C:kinetochore
GO:0005635--C:nuclear envelope
GO:0051304--P:chromosome separation
GO:0050832--P:defense response to fungus
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0000281--P:mitotic cytokinesis
GO:0008045--P:motor neuron axon guidance
GO:0040038--P:polar body extrusion after meiotic divisions
GO:0033365--P:protein localization to organelle
GO:0030334--P:regulation of cell migration

KEGG

cel:CELE_K04D7.1

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	59.79	4.00e-95	339.00
IUUC-Aml-001935	Ailuropoda melanoleuca	72.19	2.00e-133	467.00
IUUC-Atr-002694	Amborella trichopoda	59.87	2.00e-108	384.00
IUUC-Apl-003918	Anas platyrhynchos	73.85	3.00e-122	429.00
IUUC-Aca-004869	Anolis carolinensis	72.19	2.00e-133	467.00
IUUC-Aly-005806	Arabidopsis lyrata	59.88	1.00e-107	381.00
IUUC-Ath-007584	Arabidopsis thaliana	59.57	1.00e-107	381.00
IUUC-Ago-007720	Ashbya gossypii	52.66	4.00e-90	323.00
IUUC-Acl-008156	Aspergillus clavatus	65.84	1.00e-122	431.00
IUUC-Afl-008684	Aspergillus flavus	65.53	8.00e-123	431.00
IUUC-Afu-008867	Aspergillus fumigatus	66.77	4.00e-124	436.00
IUUC-Ani-009221	Aspergillus nidulans	65.53	5.00e-123	432.00
IUUC-Ang-009843	Aspergillus niger	64.91	2.00e-121	427.00
IUUC-Aor-010193	Aspergillus oryzae	65.53	8.00e-123	431.00
IUUC-Ate-010420	Aspergillus terreus	66.32	2.00e-113	400.00
IUUC-Ame-011199	Astyanax mexicanus	71.88	2.00e-133	466.00
IUUC-Bgr-012064	Blumeria graminis	63.66	2.00e-120	423.00
IUUC-Bta-013357	Bos taurus	72.19	2.00e-133	467.00
IUUC-Bci-013862	Botrytis cinerea	64.60	4.00e-122	429.00
IUUC-Bdi-014690	Brachypodium distachyon	58.79	1.00e-106	378.00
IUUC-Bol-016005	Brassica oleracea	59.39	8.00e-109	385.00
IUUC-Bra-016871	Brassica rapa	59.27	6.00e-109	385.00
IUUC-Cja-019914	Callithrix jacchus	72.19	2.00e-133	467.00
IUUC-Cfa-020755	Canis familiaris	72.19	2.00e-133	467.00
IUUC-Cpo-022377	Cavia porcellus	72.19	1.00e-133	468.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	64.26	1.00e-117	414.00
IUUC-Csa-023025	Chlorocebus sabaeus	72.19	3.00e-133	466.00
IUUC-Cin-025647	Ciona intestinalis	68.00	7.00e-127	445.00
IUUC-Csv-026027	Ciona savignyi	67.38	1.00e-126	444.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	67.01	4.00e-116	409.00
IUUC-Cne-026930	Cryptococcus neoformans	62.89	2.00e-117	413.00
IUUC-Cme-027251	Cyanidioschyzon merolae	58.49	2.00e-108	383.00
IUUC-Dre-028669	Danio rerio	72.50	1.00e-133	468.00
IUUC-Dno-029470	Dasypus novemcinctus	60.92	2.00e-106	377.00
IUUC-Dor-031098	Dipodomys ordii	65.11	2.00e-104	370.00
IUUC-Dse-031255	Dothistroma septosporum	63.98	2.00e-120	424.00
IUUC-Dme-032118	Drosophila melanogaster	67.08	3.00e-126	443.00
IUUC-Ete-033182	Echinops telfairi	65.77	2.00e-84	304.00
IUUC-Eca-033296	Equus caballus	77.03	6.00e-69	251.00
IUUC-Eeu-034771	Erinaceus europaeus	68.44	1.00e-123	434.00
IUUC-Fca-036315	Felis catus	72.19	2.00e-133	467.00
IUUC-Fal-036990	Ficedula albicollis	74.03	9.00e-77	278.00
IUUC-Fox-037702	Fusarium oxysporum	65.53	3.00e-124	436.00
IUUC-Fso-038384	Fusarium solani	65.22	3.00e-123	433.00
IUUC-Gmo-039630	Gadus morhua	71.02	1.00e-129	454.00
IUUC-Ggr-039985	Gaeumannomyces graminis	66.46	2.00e-125	440.00
IUUC-Gga-040540	Gallus gallus	72.19	2.00e-133	467.00
IUUC-Gac-041316	Gasterosteus aculeatus	69.81	1.00e-129	454.00
IUUC-Gma-042872	Glycine max	58.10	2.00e-106	377.00
IUUC-Ggo-045253	Gorilla gorilla	72.19	2.00e-133	467.00
IUUC-Hsa-046809	Homo sapiens	72.19	2.00e-133	467.00
IUUC-Hvu-047683	Hordeum vulgare	58.54	8.00e-107	378.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	72.19	2.00e-133	467.00
IUUC-Kpa-049214	Komagataella pastoris	51.55	1.00e-85	308.00
IUUC-Lch-049634	Latimeria chalumnae	71.56	5.00e-132	462.00
IUUC-Lpe-050762	Leersia perrieri	59.57	6.00e-106	375.00
IUUC-Loc-052163	Lepisosteus oculatus	72.50	5.00e-133	465.00
IUUC-Lma-053113	Leptosphaeria maculans	65.53	1.00e-123	434.00
IUUC-Laf-054422	Loxodonta africana	72.19	2.00e-133	467.00
IUUC-Mcc-055348	Macaca mulatta	72.19	3.00e-133	466.00
IUUC-Meu-056543	Macropus eugenii	71.96	1.00e-133	467.00
IUUC-Mor-057107	Magnaporthe oryzae	66.46	1.00e-125	441.00
IUUC-Mpo-057487	Magnaporthe poae	66.15	6.00e-125	438.00
IUUC-Mtr-058808	Medicago truncatula	59.02	4.00e-108	382.00
IUUC-Mla-058909	Melampsora laricipopulina	66.04	3.00e-125	439.00
IUUC-Mga-059387	Meleagris gallopavo	72.19	2.00e-133	467.00
IUUC-Mvi-060392	Microbotryum violaceum	63.52	7.00e-118	415.00
IUUC-Mmr-061141	Microcebus murinus	65.86	3.00e-100	356.00
IUUC-Mdo-062932	Monodelphis domestica	72.19	2.00e-133	467.00
IUUC-Mmu-064132	Mus musculus	72.19	2.00e-133	467.00
IUUC-Mac-064447	Musa acuminata	55.21	7.00e-95	338.00
IUUC-Mpu-066721	Mustela putorius furo	71.56	1.00e-130	457.00
IUUC-Mlu-068221	Myotis lucifugus	70.31	4.00e-124	436.00
IUUC-Nfi-068344	Neosartorya fischeri	66.77	5.00e-124	436.00
IUUC-Ncr-068722	Neurospora crassa	64.60	3.00e-122	430.00
IUUC-Nle-069865	Nomascus leucogenys	72.19	2.00e-133	467.00
IUUC-Opr-071100	Ochotona princeps	59.06	2.00e-99	354.00
IUUC-Ont-072287	Oreochromis niloticus	72.19	4.00e-133	466.00
IUUC-Oan-072788	Ornithorhynchus anatinus	72.19	2.00e-133	467.00
IUUC-Ocu-073844	Oryctolagus cuniculus	70.31	2.00e-127	447.00
IUUC-Oba-075981	Oryza barthii	56.31	2.00e-94	337.00
IUUC-Obr-076099	Oryza brachyantha	58.79	2.00e-105	373.00
IUUC-Ogl-077181	Oryza glaberrima	60.06	6.00e-107	379.00
IUUC-Ogu-078035	Oryza glumaepatula	60.06	6.00e-107	379.00
IUUC-Oin-079327	Oryza indica	60.06	6.00e-107	379.00
IUUC-Olo-081084	Oryza longistaminata	60.06	6.00e-107	379.00
IUUC-Ome-081612	Oryza meridionalis	60.06	6.00e-107	379.00
IUUC-Oni-082682	Oryza nivara	58.48	9.00e-104	368.00
IUUC-Opu-083308	Oryza punctata	59.45	8.00e-106	375.00
IUUC-Oru-084200	Oryza rufipogon	60.06	6.00e-107	379.00
IUUC-Osa-085488	Oryza sativa	60.06	6.00e-107	379.00
IUUC-Ola-086400	Oryzias latipes	72.50	1.00e-133	467.00
IUUC-Olu-087817	Ostreococcus lucimarinus	65.19	5.00e-119	419.00
IUUC-Oga-088811	Otolemur garnettii	72.19	2.00e-133	467.00
IUUC-Oar-089962	Ovis aries	72.19	2.00e-133	467.00
IUUC-Ptr-091340	Pan troglodytes	72.19	2.00e-133	467.00
IUUC-Pan-091946	Papio anubis	72.19	3.00e-133	466.00
IUUC-Pma-094535	Petromyzon marinus	73.75	3.00e-134	469.00
IUUC-Pno-095100	Phaeosphaeria nodorum	67.74	3.00e-84	303.00
IUUC-Ppa-095752	Physcomitrella patens	66.77	3.00e-119	419.00
IUUC-Pfo-097311	Poecilia formosa	71.88	1.00e-132	464.00
IUUC-Pab-097863	Pongo abelii	72.19	2.00e-133	467.00
IUUC-Pop-099345	Populus trichocarpa	60.00	5.00e-109	385.00
IUUC-Pca-100594	Procavia capensis	71.88	2.00e-132	464.00
IUUC-Ppe-101743	Prunus persica	58.05	1.00e-105	375.00
IUUC-Pva-102746	Pteropus vampyrus	59.69	6.00e-102	362.00
IUUC-Pgr-103375	Puccinia graminis	50.31	6.00e-84	302.00
IUUC-Ptt-103839	Puccinia triticina	66.35	2.00e-125	440.00
IUUC-Pte-104026	Pyrenophora teres	65.53	1.00e-123	434.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	65.53	1.00e-123	434.00
IUUC-Rno-104964	Rattus norvegicus	72.19	2.00e-133	467.00
IUUC-Sce-106224	Saccharomyces cerevisiae	49.06	1.00e-84	305.00
IUUC-Sha-107409	Sarcophilus harrisii	72.19	2.00e-133	467.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	60.50	5.00e-111	392.00
IUUC-Spo-108297	Schizosaccharomyces pombe	58.62	6.00e-107	379.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	64.60	4.00e-122	429.00
IUUC-Smo-109017	Selaginella moellendorffii	65.59	9.00e-115	405.00
IUUC-Sit-110680	Setaria italica	58.48	2.00e-105	374.00
IUUC-Sly-111839	Solanum lycopersicum	59.04	6.00e-109	385.00
IUUC-Stu-112775	Solanum tuberosum	59.57	6.00e-109	385.00
IUUC-Sar-113173	Sorex araneus	72.19	2.00e-133	467.00
IUUC-Sbi-114681	Sorghum bicolor	58.36	6.00e-106	375.00
IUUC-Sre-115107	Sporisorium reilianum	65.52	1.00e-124	437.00
IUUC-Ssc-116218	Sus scrofa	70.31	2.00e-131	460.00
IUUC-Tru-118202	Takifugu rubripes	71.56	1.00e-131	461.00
IUUC-Tni-120260	Tetraodon nigroviridis	70.62	7.00e-130	455.00
IUUC-Tca-120951	Theobroma cacao	59.33	2.00e-108	383.00
IUUC-Tre-121961	Trichoderma reesei	66.15	2.00e-124	437.00
IUUC-Tvi-122447	Trichoderma virens	65.84	2.00e-123	434.00
IUUC-Tae-123560	Triticum aestivum	58.23	2.00e-106	377.00
IUUC-Tur-126335	Triticum urartu	62.88	6.00e-96	342.00
IUUC-Tme-127105	Tuber melanosporum	60.69	1.00e-109	387.00
IUUC-Tbe-128021	Tupaia belangeri	63.00	2.00e-64	236.00
IUUC-Ttr-128637	Tursiops truncatus	61.37	7.00e-107	379.00
IUUC-Uma-129634	Ustilago maydis	65.41	1.00e-123	434.00
IUUC-Vda-129923	Verticillium dahliae	64.60	3.00e-123	433.00
IUUC-Vpa-130410	Vicugna pacos	80.00	1.00e-80	291.00
IUUC-Vvi-131115	Vitis vinifera	58.36	9.00e-108	381.00
IUUC-Xtr-132105	Xenopus tropicalis	72.50	3.00e-133	466.00
IUUC-Xma-133875	Xiphophorus maculatus	71.88	1.00e-132	464.00
IUUC-Yli-134624	Yarrowia lipolytica	57.76	4.00e-106	376.00
IUUC-Zma-134711	Zea mays	58.61	2.00e-105	374.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence