iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012797

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Striatin-3

Genbank Nucleotide ID

BC140553

Gene Name

STRN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000021845.5	ENSBTAT00000029119.5	ENSBTAP00000029119.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-26	91.2	585	615
UBD/Beta-Prp	5.60e-54	183.5	574	794

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd..tllvsGsdDgtikvWDl 30
           Htd v++la+s+  + l+s+s Dgt+++W++
   Q: 585  HTDAVWGLAYSGikNQLLSCSADGTVRLWNP 615
           **********666689*************95 PP

UBD/Beta-Prp

   S: 40   ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsv..lslsfsp.sgdklvsGshdrtirvwdle 124
           ++  l  +l  h+++v+ + +s  ++ l+++s D+t+++w+++ + +c+ t++g ++    +s++f   +  ++v+  +     ++dle
   Q: 574  EPNVLAGTLIAHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQeKLPCICTYNGDKEHGipTSVDFIGcDPAHMVTSFNTGSTVIYDLE 662
           455668899*******************************887699*******7655541245555554449999999999999***** PP
   S: 125  tgqclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
           t q l           + +  +n vv+hp+  + ++++ Dr ++++d ktgk+++ +   h d+v+sl++d+ng +l+sgs+d +++lw
   Q: 663  TSQSLVMlssqmdSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVA-HLDAVTSLAVDPNGIYLMSGSHDCSIRLW 750
           *****9888886633344556899999**99**************************98.***************************** PP
   S: 208  dlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           +l +++cv++ ++h+    + +++v+f+p + +++s+++D   +
   Q: 751  NLDSKTCVQEITAHRkkldESIYDVAFHPSKAYIASAGADALAK 794
           ***************99999*******************97665 PP

Organism

Bos taurus

Functional Description
(View)

Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity).

Protein Sequence
(Fasta)

MDELAGGGGG GPAMASPPRQ QQGPGGNMSL SPGGNGAAGG GGPPATEGAG PAAGPELSRP 60
QQYTIPGILH YIQHEWARFE MERAHWEVER AELQARIAFL QGERKGQENL KKDLVRRIKM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGATGGA GGAGGGACTG TAATGGCGGC GGCCGGCAGC TCCCTGCTCT GACCCACGGC 60
AGGCATACAG CAACGACCCC CTCCCTGCCC CTCTCTCTGC CGGCCTCCGC CCCGCCGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0112--Calmodulin-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0000159--C:protein phosphatase type 2A complex
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

KEGG

bta:516375

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002046	Ailuropoda melanoleuca	97.03	0.00e+00	1357.00
IUUC-Apl-003472	Anas platyrhynchos	95.20	0.00e+00	1271.00
IUUC-Aca-005286	Anolis carolinensis	94.36	0.00e+00	1318.00
IUUC-Afl-008585	Aspergillus flavus	27.65	2.00e-36	147.00
IUUC-Ani-009405	Aspergillus nidulans	29.92	4.00e-36	146.00
IUUC-Aor-009982	Aspergillus oryzae	27.65	2.00e-36	147.00
IUUC-Bgr-012143	Blumeria graminis	25.89	2.00e-35	144.00
IUUC-Bci-013742	Botrytis cinerea	25.45	1.00e-35	145.00
IUUC-Cel-018443	Caenorhabditis elegans	40.08	2.00e-101	363.00
IUUC-Cja-018786	Callithrix jacchus	97.58	0.00e+00	1377.00
IUUC-Cfa-021098	Canis familiaris	95.42	0.00e+00	1328.00
IUUC-Cpo-022357	Cavia porcellus	95.03	0.00e+00	1329.00
IUUC-Csa-023725	Chlorocebus sabaeus	98.11	0.00e+00	1384.00
IUUC-Cho-024338	Choloepus hoffmanni	92.46	0.00e+00	1197.00
IUUC-Cin-025167	Ciona intestinalis	49.21	0.00e+00	657.00
IUUC-Csv-026143	Ciona savignyi	52.32	0.00e+00	678.00
IUUC-Cgl-026487	Colletotrichum gloeosporioides	26.13	2.00e-31	130.00
IUUC-Cne-026783	Cryptococcus neoformans	32.79	8.00e-57	215.00
IUUC-Dno-029926	Dasypus novemcinctus	97.44	0.00e+00	1370.00
IUUC-Dse-031486	Dothistroma septosporum	27.48	2.00e-37	151.00
IUUC-Dme-032158	Drosophila melanogaster	63.86	4.00e-144	504.00
IUUC-Ete-032770	Echinops telfairi	82.88	0.00e+00	1143.00
IUUC-Eca-033309	Equus caballus	97.58	0.00e+00	1362.00
IUUC-Eeu-034939	Erinaceus europaeus	94.65	0.00e+00	1015.00
IUUC-Fca-035719	Felis catus	95.63	0.00e+00	1249.00
IUUC-Fal-037408	Ficedula albicollis	95.01	0.00e+00	1214.00
IUUC-Fox-037678	Fusarium oxysporum	26.23	4.00e-36	146.00
IUUC-Fso-038364	Fusarium solani	26.45	3.00e-37	150.00
IUUC-Gmo-039653	Gadus morhua	63.28	0.00e+00	872.00
IUUC-Ggr-039846	Gaeumannomyces graminis	26.02	2.00e-34	140.00
IUUC-Gga-041218	Gallus gallus	95.44	0.00e+00	1352.00
IUUC-Gac-042142	Gasterosteus aculeatus	71.68	0.00e+00	1054.00
IUUC-Ggo-045607	Gorilla gorilla	78.98	0.00e+00	1034.00
IUUC-Hsa-045717	Homo sapiens	97.71	0.00e+00	1392.00
IUUC-Itr-048177	Ictidomys tridecemlineatus	97.31	0.00e+00	963.00
IUUC-Lch-050441	Latimeria chalumnae	90.07	0.00e+00	1320.00
IUUC-Loc-052193	Lepisosteus oculatus	86.23	0.00e+00	1271.00
IUUC-Lma-053183	Leptosphaeria maculans	28.60	1.00e-39	158.00
IUUC-Laf-053964	Loxodonta africana	97.11	0.00e+00	1370.00
IUUC-Mcc-055639	Macaca mulatta	98.11	0.00e+00	1386.00
IUUC-Mor-057148	Magnaporthe oryzae	42.31	1.00e-17	85.50
IUUC-Mpo-057337	Magnaporthe poae	25.07	2.00e-30	127.00
IUUC-Mla-058988	Melampsora laricipopulina	34.31	7.00e-64	239.00
IUUC-Mmr-061084	Microcebus murinus	97.98	0.00e+00	1382.00
IUUC-Mdo-063016	Monodelphis domestica	96.41	0.00e+00	1390.00
IUUC-Mmu-063914	Mus musculus	96.77	0.00e+00	1378.00
IUUC-Mpu-066348	Mustela putorius furo	89.49	0.00e+00	1262.00
IUUC-Mlu-067303	Myotis lucifugus	95.56	0.00e+00	1321.00
IUUC-Nle-070032	Nomascus leucogenys	97.71	0.00e+00	1392.00
IUUC-Opr-070496	Ochotona princeps	91.12	0.00e+00	654.00
IUUC-Ont-072075	Oreochromis niloticus	71.81	0.00e+00	1055.00
IUUC-Oan-072822	Ornithorhynchus anatinus	95.00	0.00e+00	1215.00
IUUC-Ocu-073876	Oryctolagus cuniculus	94.65	0.00e+00	1336.00
IUUC-Ola-086321	Oryzias latipes	69.53	0.00e+00	997.00
IUUC-Oga-088045	Otolemur garnettii	98.24	0.00e+00	1379.00
IUUC-Oar-089737	Ovis aries	99.29	0.00e+00	1311.00
IUUC-Ptr-090871	Pan troglodytes	97.72	0.00e+00	1311.00
IUUC-Pan-092139	Papio anubis	97.59	0.00e+00	1286.00
IUUC-Psi-093424	Pelodiscus sinensis	95.14	0.00e+00	1284.00
IUUC-Pma-094286	Petromyzon marinus	70.92	0.00e+00	683.00
IUUC-Pno-094905	Phaeosphaeria nodorum	28.16	1.00e-35	145.00
IUUC-Pfo-096564	Poecilia formosa	72.68	0.00e+00	1069.00
IUUC-Pab-098626	Pongo abelii	97.71	0.00e+00	1428.00
IUUC-Pva-102445	Pteropus vampyrus	91.59	0.00e+00	1278.00
IUUC-Ptt-103828	Puccinia triticina	37.12	1.00e-48	189.00
IUUC-Pte-104374	Pyrenophora teres	28.11	3.00e-33	137.00
IUUC-Pyt-104568	Pyrenophora triticirepentis	27.65	2.00e-36	147.00
IUUC-Rno-105999	Rattus norvegicus	94.73	0.00e+00	1408.00
IUUC-Sha-106786	Sarcophilus harrisii	94.86	0.00e+00	1290.00
IUUC-Ssl-108495	Sclerotinia sclerotiorum	26.30	4.00e-35	143.00
IUUC-Sar-113296	Sorex araneus	77.62	0.00e+00	865.00
IUUC-Sre-115115	Sporisorium reilianum	34.70	2.00e-63	237.00
IUUC-Tgu-117199	Taeniopygia guttata	91.38	0.00e+00	1191.00
IUUC-Tsy-119356	Tarsius syrichta	82.19	0.00e+00	966.00
IUUC-Tre-122113	Trichoderma reesei	27.49	9.00e-39	155.00
IUUC-Tvi-122312	Trichoderma virens	26.35	1.00e-36	148.00
IUUC-Tme-126990	Tuber melanosporum	26.63	1.00e-35	145.00
IUUC-Tbe-127691	Tupaia belangeri	80.50	0.00e+00	788.00
IUUC-Ttr-128600	Tursiops truncatus	89.88	0.00e+00	1269.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence