iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000000451.1	ENSORLT00000000555.1	ENSORLP00000000555.1
ENSORLG00000000451.1	ENSORLT00000000556.1	ENSORLP00000000556.1
ENSORLG00000000451.1	ENSORLT00000000558.1	ENSORLP00000000558.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-98	330.0	45	377

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 45   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 126
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l++ek+++k++ + +++ +   +++e ++k ++++++d+Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 127  MQQDAHEFLNYLLNTVADILQEEKKQEKQNGRLKNNGTPVTSEPEMENKIEPTWVHDIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 215
           ********************77666666666666666666668888888999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 216  EQNT-----SITHCLRDFSNTETLCSEYKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 297
           ****.....9**********************************************************************55555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts  ++++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 298  TSG-DAVNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 377
           774.45556****************************.888*******************999*****************97 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

KKVFGSWQLI VFLNLYSRLS TQGTNASALE KDIGPEQFPI NEHYFGLVNF GNTCYCNSVL 60
QALYFCRPFR ENVLAYKAQQ KKKENLLTCL ADLFHSIATQ KKKVGVIPPK KFISRLRKEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGTCA GAAACATCGC CTCCATCTGT AATATGGTGA GTTCCTCTCT GCCTTCAGCT 60
GGGATGTCAG AACGGCGCTG GGTTGATTTG TCACAGAGAT TGATTGACAG GTGAGGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002353	Ailuropoda melanoleuca	91.91	0.00e+00	671.00
IUUC-Apl-003380	Anas platyrhynchos	94.96	0.00e+00	670.00
IUUC-Aca-005031	Anolis carolinensis	93.39	0.00e+00	705.00
IUUC-Ath-006663	Arabidopsis thaliana	58.95	2.00e-124	438.00
IUUC-Ago-007871	Ashbya gossypii	37.16	2.00e-48	187.00
IUUC-Ame-010862	Astyanax mexicanus	96.14	0.00e+00	728.00
IUUC-Bta-013023	Bos taurus	93.66	0.00e+00	671.00
IUUC-Bdi-014008	Brachypodium distachyon	60.16	1.00e-125	442.00
IUUC-Cel-018379	Caenorhabditis elegans	61.48	3.00e-142	498.00
IUUC-Cja-018956	Callithrix jacchus	94.44	0.00e+00	669.00
IUUC-Cfa-021064	Canis familiaris	94.13	0.00e+00	660.00
IUUC-Cpo-022443	Cavia porcellus	93.41	0.00e+00	669.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.76	1.00e-98	352.00
IUUC-Csa-023841	Chlorocebus sabaeus	93.39	0.00e+00	669.00
IUUC-Cne-026900	Cryptococcus neoformans	42.18	5.00e-60	225.00
IUUC-Dre-028230	Danio rerio	94.78	0.00e+00	722.00
IUUC-Dno-029209	Dasypus novemcinctus	93.41	0.00e+00	667.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	2.00e-100	359.00
IUUC-Eca-033721	Equus caballus	95.24	0.00e+00	667.00
IUUC-Eeu-034916	Erinaceus europaeus	92.93	8.00e-154	535.00
IUUC-Fca-036299	Felis catus	94.97	0.00e+00	670.00
IUUC-Gmo-038611	Gadus morhua	95.52	0.00e+00	710.00
IUUC-Ggr-039806	Gaeumannomyces graminis	43.79	2.00e-75	276.00
IUUC-Gga-041157	Gallus gallus	93.39	0.00e+00	671.00
IUUC-Gac-041764	Gasterosteus aculeatus	95.59	0.00e+00	718.00
IUUC-Ggo-044659	Gorilla gorilla	93.94	0.00e+00	668.00
IUUC-Hsa-046156	Homo sapiens	93.39	0.00e+00	669.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	93.39	0.00e+00	669.00
IUUC-Kpa-049250	Komagataella pastoris	44.03	3.00e-68	252.00
IUUC-Lch-049969	Latimeria chalumnae	92.84	0.00e+00	660.00
IUUC-Loc-052479	Lepisosteus oculatus	89.26	0.00e+00	678.00
IUUC-Laf-054085	Loxodonta africana	93.39	0.00e+00	669.00
IUUC-Mcc-055566	Macaca mulatta	94.43	0.00e+00	669.00
IUUC-Mpo-057424	Magnaporthe poae	42.86	3.00e-75	276.00
IUUC-Mla-059142	Melampsora laricipopulina	54.39	7.00e-95	342.00
IUUC-Mga-059575	Meleagris gallopavo	94.72	0.00e+00	671.00
IUUC-Mdo-062579	Monodelphis domestica	93.39	0.00e+00	669.00
IUUC-Mmu-063611	Mus musculus	93.39	0.00e+00	669.00
IUUC-Mac-065323	Musa acuminata	60.34	1.00e-121	429.00
IUUC-Mpu-066038	Mustela putorius furo	94.21	0.00e+00	671.00
IUUC-Mlu-068183	Myotis lucifugus	92.14	0.00e+00	669.00
IUUC-Nle-069330	Nomascus leucogenys	93.39	0.00e+00	669.00
IUUC-Opr-070980	Ochotona princeps	94.68	0.00e+00	666.00
IUUC-Ont-072134	Oreochromis niloticus	96.97	0.00e+00	738.00
IUUC-Oan-073583	Ornithorhynchus anatinus	91.04	0.00e+00	663.00
IUUC-Ocu-074923	Oryctolagus cuniculus	94.97	0.00e+00	669.00
IUUC-Olu-087809	Ostreococcus lucimarinus	48.31	2.00e-80	292.00
IUUC-Oga-088073	Otolemur garnettii	95.24	0.00e+00	667.00
IUUC-Oar-089248	Ovis aries	94.72	0.00e+00	671.00
IUUC-Ptr-090814	Pan troglodytes	93.39	0.00e+00	669.00
IUUC-Pan-091753	Papio anubis	93.39	0.00e+00	669.00
IUUC-Psi-094012	Pelodiscus sinensis	91.98	0.00e+00	672.00
IUUC-Pma-094388	Petromyzon marinus	88.83	0.00e+00	675.00
IUUC-Pfo-097369	Poecilia formosa	97.52	0.00e+00	741.00
IUUC-Pab-098594	Pongo abelii	94.96	0.00e+00	668.00
IUUC-Pca-100913	Procavia capensis	78.99	2.00e-150	525.00
IUUC-Pva-102892	Pteropus vampyrus	94.96	0.00e+00	668.00
IUUC-Rno-104909	Rattus norvegicus	93.11	0.00e+00	668.00
IUUC-Sha-107400	Sarcophilus harrisii	91.91	0.00e+00	670.00
IUUC-Ssc-115550	Sus scrofa	94.96	0.00e+00	668.00
IUUC-Tgu-116800	Taeniopygia guttata	91.69	0.00e+00	671.00
IUUC-Tru-118212	Takifugu rubripes	95.87	0.00e+00	729.00
IUUC-Tni-120071	Tetraodon nigroviridis	96.14	0.00e+00	733.00
IUUC-Tme-126890	Tuber melanosporum	47.04	6.00e-92	331.00
IUUC-Vpa-130590	Vicugna pacos	90.48	1.00e-179	622.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence