iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-16	60.7	427	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek.slveCekCrewfHpaClkls..veeelpnsekwiCpkCrs 53
           +ClvCg+ g++ + s+v C++C + +H  C+ l    ++ + ++  w C +C+ 
   Q: 427  MCLVCGSIGKGPEgSMVACSNCAQTYHTYCVTLHdkLNSAVVGRG-WRCLDCTV 479
           8**********999*******************966666666665.******86 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MICIECGGTA FNNTELCENC MDVNRSGTMS LDMARQCDMS SSCGSCQRMI TADSRQCTTC 60
RKSYHLSCDS SDVSSLNNFV CISCRRRSQM LPDDVMLSAS ARPSRGQDAP LSPFSDPSVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCAAATTC GTATCGATTG AAGCTTCAAA AATCGAGAAA GCCGACTATA TGAAGTCCAA 60
AAGATGATTG TAAGTGTTCA CCGTTCAAAA TTTTAACTAT ACATCAAAAT TAAAATTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0051568--P:histone H3-K4 methylation
GO:0040028--P:regulation of vulval development

KEGG

cel:CELE_T12D8.1

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	35.33	1.00e-100	362.00
IUUC-Atr-002455	Amborella trichopoda	41.29	4.00e-30	125.00
IUUC-Apl-003311	Anas platyrhynchos	35.33	3.00e-97	350.00
IUUC-Aca-005364	Anolis carolinensis	36.72	2.00e-93	338.00
IUUC-Aly-006293	Arabidopsis lyrata	48.61	3.00e-35	142.00
IUUC-Ath-006690	Arabidopsis thaliana	44.51	1.00e-35	144.00
IUUC-Ani-009406	Aspergillus nidulans	54.17	7.00e-10	57.80
IUUC-Ame-010612	Astyanax mexicanus	37.19	4.00e-63	237.00
IUUC-Bta-012322	Bos taurus	34.82	3.00e-95	344.00
IUUC-Bdi-014882	Brachypodium distachyon	27.66	2.00e-19	89.40
IUUC-Bol-016540	Brassica oleracea	45.78	1.00e-35	144.00
IUUC-Bra-017732	Brassica rapa	29.65	9.00e-24	103.00
IUUC-Cja-019983	Callithrix jacchus	35.33	6.00e-101	363.00
IUUC-Cfa-020903	Canis familiaris	35.33	2.00e-100	361.00
IUUC-Cpo-021732	Cavia porcellus	35.16	2.00e-100	361.00
IUUC-Cre-022891	Chlamydomonas reinhardtii	46.56	2.00e-30	127.00
IUUC-Csa-023083	Chlorocebus sabaeus	35.16	9.00e-101	362.00
IUUC-Cho-024652	Choloepus hoffmanni	43.14	1.00e-33	139.00
IUUC-Cin-025724	Ciona intestinalis	47.06	1.00e-36	147.00
IUUC-Csv-026268	Ciona savignyi	46.41	4.00e-35	142.00
IUUC-Cme-027224	Cyanidioschyzon merolae	36.71	2.00e-12	66.60
IUUC-Dre-028110	Danio rerio	36.36	2.00e-108	387.00
IUUC-Dno-029932	Dasypus novemcinctus	36.94	1.00e-98	355.00
IUUC-Dor-030569	Dipodomys ordii	32.97	2.00e-84	308.00
IUUC-Dme-031590	Drosophila melanogaster	37.88	3.00e-46	179.00
IUUC-Ete-032572	Echinops telfairi	36.26	3.00e-86	314.00
IUUC-Eca-033945	Equus caballus	45.77	6.00e-58	219.00
IUUC-Eeu-034848	Erinaceus europaeus	42.08	4.00e-50	194.00
IUUC-Fca-035922	Felis catus	35.33	6.00e-102	366.00
IUUC-Fal-037179	Ficedula albicollis	36.08	2.00e-91	332.00
IUUC-Gmo-038719	Gadus morhua	35.99	7.00e-62	233.00
IUUC-Gga-040815	Gallus gallus	38.37	2.00e-46	182.00
IUUC-Gac-042436	Gasterosteus aculeatus	36.56	3.00e-65	244.00
IUUC-Gma-043554	Glycine max	42.22	1.00e-35	143.00
IUUC-Ggo-044812	Gorilla gorilla	35.16	1.00e-100	362.00
IUUC-Hsa-046595	Homo sapiens	34.99	4.00e-96	347.00
IUUC-Hvu-047762	Hordeum vulgare	28.05	8.00e-12	63.90
IUUC-Itr-048303	Ictidomys tridecemlineatus	35.33	2.00e-100	362.00
IUUC-Lch-050086	Latimeria chalumnae	35.68	3.00e-99	357.00
IUUC-Lpe-051476	Leersia perrieri	26.67	3.00e-15	75.90
IUUC-Loc-051979	Lepisosteus oculatus	36.17	2.00e-65	245.00
IUUC-Laf-054377	Loxodonta africana	36.94	2.00e-99	358.00
IUUC-Mcc-054868	Macaca mulatta	35.16	9.00e-101	362.00
IUUC-Meu-055992	Macropus eugenii	36.90	2.00e-99	358.00
IUUC-Mor-056964	Magnaporthe oryzae	54.35	3.00e-10	58.90
IUUC-Mtr-058327	Medicago truncatula	43.21	2.00e-34	140.00
IUUC-Mga-059541	Meleagris gallopavo	30.67	2.00e-65	245.00
IUUC-Mmr-061092	Microcebus murinus	35.16	2.00e-100	361.00
IUUC-Mdo-062610	Monodelphis domestica	44.28	2.00e-53	204.00
IUUC-Mmu-063903	Mus musculus	37.11	3.00e-99	357.00
IUUC-Mac-064935	Musa acuminata	29.11	5.00e-21	95.50
IUUC-Mpu-066366	Mustela putorius furo	35.16	2.00e-96	348.00
IUUC-Mlu-068201	Myotis lucifugus	35.51	1.00e-100	362.00
IUUC-Nfi-068246	Neosartorya fischeri	45.61	7.00e-09	54.30
IUUC-Nle-069232	Nomascus leucogenys	35.16	4.00e-100	360.00
IUUC-Opr-070304	Ochotona princeps	43.43	4.00e-52	201.00
IUUC-Ont-071881	Oreochromis niloticus	37.81	4.00e-67	250.00
IUUC-Oan-072945	Ornithorhynchus anatinus	35.51	1.00e-100	362.00
IUUC-Ocu-074920	Oryctolagus cuniculus	35.16	1.00e-100	362.00
IUUC-Oba-075647	Oryza barthii	41.92	7.00e-33	134.00
IUUC-Obr-076458	Oryza brachyantha	27.60	9.00e-19	87.40
IUUC-Ogl-077851	Oryza glaberrima	27.66	6.00e-19	88.20
IUUC-Ogu-078706	Oryza glumaepatula	28.05	7.00e-19	88.20
IUUC-Oin-079802	Oryza indica	26.34	6.00e-14	71.20
IUUC-Olo-080577	Oryza longistaminata	45.83	2.00e-32	132.00
IUUC-Ome-081214	Oryza meridionalis	41.92	2.00e-32	133.00
IUUC-Oni-083000	Oryza nivara	41.92	7.00e-33	134.00
IUUC-Opu-083842	Oryza punctata	41.92	1.00e-32	134.00
IUUC-Oru-084361	Oryza rufipogon	42.59	8.00e-33	134.00
IUUC-Osa-085421	Oryza sativa	28.05	1.00e-18	87.00
IUUC-Ola-086384	Oryzias latipes	37.77	4.00e-67	250.00
IUUC-Olu-087718	Ostreococcus lucimarinus	36.65	2.00e-25	110.00
IUUC-Oga-088450	Otolemur garnettii	37.11	1.00e-99	358.00
IUUC-Oar-089975	Ovis aries	37.11	2.00e-99	358.00
IUUC-Ptr-091527	Pan troglodytes	35.16	6.00e-101	363.00
IUUC-Pan-092102	Papio anubis	35.16	1.00e-100	362.00
IUUC-Psi-094059	Pelodiscus sinensis	44.16	2.00e-35	145.00
IUUC-Pma-094252	Petromyzon marinus	40.79	9.00e-50	192.00
IUUC-Ppa-095221	Physcomitrella patens	30.09	2.00e-24	106.00
IUUC-Pfo-096835	Poecilia formosa	37.78	1.00e-105	378.00
IUUC-Pab-098241	Pongo abelii	35.38	7.00e-64	239.00
IUUC-Pop-099620	Populus trichocarpa	27.62	2.00e-20	93.60
IUUC-Pca-100103	Procavia capensis	35.16	1.00e-99	358.00
IUUC-Ppe-101920	Prunus persica	29.91	9.00e-22	97.80
IUUC-Pva-102898	Pteropus vampyrus	36.60	9.00e-95	342.00
IUUC-Rno-105660	Rattus norvegicus	35.23	2.00e-86	315.00
IUUC-Sha-106550	Sarcophilus harrisii	35.68	1.00e-100	362.00
IUUC-Smo-109164	Selaginella moellendorffii	41.24	1.00e-29	124.00
IUUC-Sit-110552	Setaria italica	28.09	1.00e-19	90.50
IUUC-Sly-111158	Solanum lycopersicum	47.92	4.00e-35	142.00
IUUC-Stu-112529	Solanum tuberosum	48.61	3.00e-35	142.00
IUUC-Sar-113183	Sorex araneus	39.01	5.00e-48	187.00
IUUC-Sbi-114254	Sorghum bicolor	25.45	3.00e-09	55.80
IUUC-Ssc-115678	Sus scrofa	36.57	4.00e-96	347.00
IUUC-Tgu-116677	Taeniopygia guttata	35.33	2.00e-97	351.00
IUUC-Tru-118141	Takifugu rubripes	38.27	4.00e-113	403.00
IUUC-Tsy-118932	Tarsius syrichta	34.99	5.00e-100	360.00
IUUC-Tni-119970	Tetraodon nigroviridis	28.87	1.00e-75	279.00
IUUC-Tca-121624	Theobroma cacao	28.32	4.00e-22	99.00
IUUC-Tre-122041	Trichoderma reesei	37.97	2.00e-05	44.30
IUUC-Tae-125629	Triticum aestivum	29.23	2.00e-12	65.90
IUUC-Tme-127087	Tuber melanosporum	51.11	4.00e-11	63.20
IUUC-Tbe-127950	Tupaia belangeri	44.44	4.00e-36	147.00
IUUC-Ttr-129051	Tursiops truncatus	30.87	5.00e-77	283.00
IUUC-Vpa-130660	Vicugna pacos	41.46	2.00e-27	119.00
IUUC-Vvi-130873	Vitis vinifera	41.14	3.00e-35	142.00
IUUC-Xtr-132455	Xenopus tropicalis	35.06	5.00e-92	333.00
IUUC-Xma-133751	Xiphophorus maculatus	37.61	3.00e-104	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence