iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062958

UUCD1 version

UUC-MoD-00282

Ensembl Protein ID

ENSMODP00000031842.2

UniProt Accession

F6UQ46; F6UQ46_MONDO

Protein Name

Uncharacterized protein

Gene Name

TRIM40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000023828.2	ENSMODT00000033416.2	ENSMODP00000031842.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.60e-10	39.1	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC+e +++ p++++CgH+f++ Cl q+   +k ++   f+CP+Cr
   Q: 14   CPICQELLRE-PVSTDCGHFFCQACLiQHA--KKALEEDVFYCPVCR 57
           ********88.**************97666..7889**********8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MNPQPESSPE KGLCPICQEL LREPVSTDCG HFFCQACLIQ HAKKALEEDV FYCPVCRKLC 60
SQSILGAGYY CEVHQKKVGW FCEEKQVFLC PDCYKSPEHQ DHYDQPIDKA IIHYKERIHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAACCTCAG TTTCCTTACC AATAAAAGAG ATATAGCACT TCTTGCCTCA CAGGGTTGTT 60
CTAAGGAATG CATTTTCGAC ACCTGAAAGC TCTCTATACA TTTTAAATTG TTAAGTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box

SMART

SM00184--RING

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042177--P:negative regulation of protein catabolic process
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001427	Ailuropoda melanoleuca	36.86	3.00e-32	131.00
IUUC-Bta-012543	Bos taurus	41.44	2.00e-38	152.00
IUUC-Cel-018714	Caenorhabditis elegans	35.85	2.00e-05	43.10
IUUC-Cja-018793	Callithrix jacchus	38.84	5.00e-32	130.00
IUUC-Csa-023101	Chlorocebus sabaeus	42.34	9.00e-43	166.00
IUUC-Cho-024926	Choloepus hoffmanni	47.89	1.00e-15	77.00
IUUC-Dno-029338	Dasypus novemcinctus	36.00	9.00e-28	116.00
IUUC-Dor-030164	Dipodomys ordii	44.24	2.00e-34	139.00
IUUC-Ete-032446	Echinops telfairi	32.27	8.00e-25	107.00
IUUC-Eca-034042	Equus caballus	44.89	2.00e-45	175.00
IUUC-Eeu-034444	Erinaceus europaeus	43.75	3.00e-41	161.00
IUUC-Fso-038265	Fusarium solani	37.74	8.00e-07	47.40
IUUC-Ggo-044410	Gorilla gorilla	44.39	2.00e-44	172.00
IUUC-Hsa-046211	Homo sapiens	43.95	3.00e-43	168.00
IUUC-Itr-048126	Ictidomys tridecemlineatus	37.50	7.00e-37	147.00
IUUC-Laf-054019	Loxodonta africana	53.54	2.00e-28	118.00
IUUC-Mcc-054616	Macaca mulatta	46.19	3.00e-49	188.00
IUUC-Meu-055981	Macropus eugenii	51.35	2.00e-51	195.00
IUUC-Mmu-063571	Mus musculus	44.39	4.00e-40	157.00
IUUC-Opr-071083	Ochotona princeps	42.36	9.00e-43	166.00
IUUC-Ocu-073939	Oryctolagus cuniculus	40.99	3.00e-36	145.00
IUUC-Oga-088040	Otolemur garnettii	44.69	1.00e-41	162.00
IUUC-Oar-089914	Ovis aries	45.37	3.00e-46	178.00
IUUC-Ptr-091240	Pan troglodytes	55.12	2.00e-39	155.00
IUUC-Pan-092095	Papio anubis	46.19	8.00e-49	186.00
IUUC-Pab-098406	Pongo abelii	44.84	2.00e-45	175.00
IUUC-Pca-101043	Procavia capensis	45.09	4.00e-42	164.00
IUUC-Pva-102651	Pteropus vampyrus	47.06	5.00e-50	190.00
IUUC-Rno-106090	Rattus norvegicus	41.28	8.00e-38	150.00
IUUC-Sce-106215	Saccharomyces cerevisiae	37.78	1.00e-05	43.50
IUUC-Ssc-115942	Sus scrofa	46.90	6.00e-52	197.00
IUUC-Tsy-119497	Tarsius syrichta	43.81	3.00e-43	168.00
IUUC-Tbe-127279	Tupaia belangeri	39.06	2.00e-28	119.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence