iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-21	75.6	486	514
UBD/Beta-Prp	3.30e-50	171.2	267	464

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWD 29
           gH++ +++++ +++++vsGs+D tik+W 
   Q: 486  GHESAISSIDIHGNHIVSGSWDRTIKMWT 514
           8**********559**************6 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshd.rtirv..wdletgqcleetlsghdgvvncv 143
           +s sg++  vta +f+++++il+t+ + ++i + ++ ++  vh l+  e ++ +++++ +gd+l++G    +t+++  w++++++ +   ++ h+  ++++
   Q: 267  SSGSGKSVDVTAARFHKETNILATAFNNGVIVLHEIPSFALVHNLRVSEMRIQTVAWNLTGDWLAIGCGKgSTAQLvvWEWQSESYVM-KQQAHSLRITTA 366
           333777777**********************************************************66514444467*********9.9*********** PP
   S: 144  vvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.dnvksvrfspnderlvsgs 241
           +++pdg+l+++G+ D++v++W++++ ++  t+ + ht+ v+ ++++++g+ ++s+sldgtv+  dl++ +  rtl + + ++   +++++ +++++ g+
   Q: 367  EYSPDGSLMATGAEDGKVKIWNSRSSFCTVTFDE-HTSGVTAVKWTQSGRAILSASLDGTVRAHDLKRYRNFRTLVCPEpTQLATLAVDKAGDLVIAGA 464
           ********************************99.*********************************999***9997746666777777777777766 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MDTNFKLSNC IGTVYRDGQV AFSKDGYSVI SPIGNKLSIF DLRNNTSKTL DIDCNYNIKR 60
LSISPSGYHL LASDERGVVH FVHLLSEFKI YTFRSNKPIG SLQWSPDATR VAICRENDLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATTTTAGT TTTCATTATT TCTTCCATTT TCAGCTTGTT TCATTGAAGT CTTGCCATTC 60
ACTATGGACA CTAATTTCAA GGTAATTATT TGAAGCGTTA ATTATTCAAT TAATATTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027145--PWP2
IPR011044--Quino_amine_DH_bsu
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000028--P:ribosomal small subunit assembly

KEGG

cel:CELE_F55F8.3

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	37.98	0.00e+00	645.00
IUUC-Atr-003033	Amborella trichopoda	29.69	3.00e-119	421.00
IUUC-Apl-003219	Anas platyrhynchos	39.82	0.00e+00	666.00
IUUC-Aca-004950	Anolis carolinensis	39.35	0.00e+00	652.00
IUUC-Aly-006213	Arabidopsis lyrata	31.56	4.00e-130	457.00
IUUC-Ath-006593	Arabidopsis thaliana	31.54	2.00e-129	455.00
IUUC-Ago-007916	Ashbya gossypii	33.84	3.00e-146	511.00
IUUC-Acl-008225	Aspergillus clavatus	36.79	7.00e-163	566.00
IUUC-Afl-008390	Aspergillus flavus	35.55	5.00e-155	540.00
IUUC-Afu-009039	Aspergillus fumigatus	36.59	8.00e-161	559.00
IUUC-Ani-009228	Aspergillus nidulans	33.71	7.00e-134	470.00
IUUC-Ang-009663	Aspergillus niger	36.57	2.00e-153	535.00
IUUC-Aor-009923	Aspergillus oryzae	35.55	5.00e-155	540.00
IUUC-Ate-010264	Aspergillus terreus	35.44	2.00e-155	541.00
IUUC-Ame-010790	Astyanax mexicanus	37.91	3.00e-77	280.00
IUUC-Bgr-012066	Blumeria graminis	34.40	6.00e-148	516.00
IUUC-Bta-012399	Bos taurus	38.32	7.00e-180	623.00
IUUC-Bci-013757	Botrytis cinerea	34.25	7.00e-147	513.00
IUUC-Bdi-015028	Brachypodium distachyon	32.96	2.00e-130	459.00
IUUC-Bol-016521	Brassica oleracea	32.41	8.00e-129	453.00
IUUC-Bra-017096	Brassica rapa	31.21	4.00e-129	454.00
IUUC-Cja-019229	Callithrix jacchus	38.44	0.00e+00	649.00
IUUC-Cfa-020504	Canis familiaris	37.81	0.00e+00	632.00
IUUC-Cpo-021574	Cavia porcellus	37.70	0.00e+00	649.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	38.13	1.00e-111	396.00
IUUC-Csa-023436	Chlorocebus sabaeus	38.02	0.00e+00	630.00
IUUC-Cin-025397	Ciona intestinalis	38.89	5.00e-158	550.00
IUUC-Csv-026194	Ciona savignyi	41.67	5.00e-125	441.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	34.74	7.00e-148	516.00
IUUC-Cne-027031	Cryptococcus neoformans	35.67	2.00e-159	555.00
IUUC-Cme-027276	Cyanidioschyzon merolae	26.45	6.00e-78	284.00
IUUC-Dre-027514	Danio rerio	38.87	0.00e+00	633.00
IUUC-Dno-029191	Dasypus novemcinctus	37.92	3.00e-160	557.00
IUUC-Dor-030149	Dipodomys ordii	38.17	0.00e+00	649.00
IUUC-Dse-031260	Dothistroma septosporum	38.60	6.00e-118	416.00
IUUC-Dme-032043	Drosophila melanogaster	35.73	3.00e-170	590.00
IUUC-Ete-033102	Echinops telfairi	41.21	2.00e-132	465.00
IUUC-Eca-033223	Equus caballus	38.21	0.00e+00	652.00
IUUC-Fca-035795	Felis catus	36.88	2.00e-173	601.00
IUUC-Fal-036830	Ficedula albicollis	38.65	0.00e+00	653.00
IUUC-Fox-037835	Fusarium oxysporum	34.06	5.00e-145	507.00
IUUC-Fso-038324	Fusarium solani	34.62	5.00e-142	497.00
IUUC-Gmo-039355	Gadus morhua	37.77	4.00e-180	624.00
IUUC-Ggr-039840	Gaeumannomyces graminis	34.09	7.00e-135	473.00
IUUC-Gga-040907	Gallus gallus	42.99	5.00e-130	456.00
IUUC-Gac-042624	Gasterosteus aculeatus	38.76	0.00e+00	631.00
IUUC-Gma-043034	Glycine max	32.75	5.00e-142	497.00
IUUC-Hsa-046145	Homo sapiens	38.13	0.00e+00	651.00
IUUC-Hvu-047416	Hordeum vulgare	32.63	2.00e-129	455.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	38.80	0.00e+00	645.00
IUUC-Kpa-049150	Komagataella pastoris	33.79	4.00e-143	501.00
IUUC-Lch-049460	Latimeria chalumnae	35.18	1.00e-151	528.00
IUUC-Lpe-050840	Leersia perrieri	31.73	1.00e-128	452.00
IUUC-Loc-052733	Lepisosteus oculatus	38.18	0.00e+00	633.00
IUUC-Lma-053277	Leptosphaeria maculans	34.63	1.00e-150	525.00
IUUC-Laf-054294	Loxodonta africana	39.59	0.00e+00	632.00
IUUC-Mcc-054624	Macaca mulatta	38.13	0.00e+00	652.00
IUUC-Meu-056665	Macropus eugenii	34.62	1.00e-117	416.00
IUUC-Mor-057288	Magnaporthe oryzae	33.41	2.00e-142	498.00
IUUC-Mpo-057594	Magnaporthe poae	33.64	2.00e-135	475.00
IUUC-Mtr-058700	Medicago truncatula	34.05	5.00e-147	513.00
IUUC-Mla-058846	Melampsora laricipopulina	34.71	5.00e-143	500.00
IUUC-Mga-059207	Meleagris gallopavo	35.63	2.00e-159	555.00
IUUC-Mvi-060327	Microbotryum violaceum	35.09	1.00e-153	535.00
IUUC-Mmr-061264	Microcebus murinus	37.93	3.00e-179	620.00
IUUC-Mdo-062327	Monodelphis domestica	38.35	0.00e+00	653.00
IUUC-Mmu-063542	Mus musculus	37.79	0.00e+00	628.00
IUUC-Mac-065142	Musa acuminata	32.79	1.00e-135	476.00
IUUC-Mpu-066098	Mustela putorius furo	38.87	4.00e-163	567.00
IUUC-Mlu-067056	Myotis lucifugus	34.97	8.00e-151	526.00
IUUC-Nfi-068323	Neosartorya fischeri	36.57	1.00e-161	562.00
IUUC-Ncr-068925	Neurospora crassa	34.86	8.00e-158	549.00
IUUC-Nle-068970	Nomascus leucogenys	38.02	0.00e+00	644.00
IUUC-Opr-070966	Ochotona princeps	48.90	2.00e-89	321.00
IUUC-Ont-071252	Oreochromis niloticus	37.92	1.00e-176	612.00
IUUC-Oan-072737	Ornithorhynchus anatinus	37.36	5.00e-177	613.00
IUUC-Oba-075794	Oryza barthii	31.58	5.00e-124	437.00
IUUC-Obr-076617	Oryza brachyantha	32.27	2.00e-131	461.00
IUUC-Ogl-077022	Oryza glaberrima	32.37	3.00e-133	468.00
IUUC-Ogu-078757	Oryza glumaepatula	26.44	3.00e-79	288.00
IUUC-Oin-079813	Oryza indica	32.67	6.00e-135	473.00
IUUC-Olo-080265	Oryza longistaminata	32.38	4.00e-132	464.00
IUUC-Ome-081494	Oryza meridionalis	32.45	1.00e-133	469.00
IUUC-Oni-082639	Oryza nivara	26.33	2.00e-78	286.00
IUUC-Opu-084005	Oryza punctata	32.60	2.00e-132	465.00
IUUC-Oru-084883	Oryza rufipogon	26.44	4.00e-79	288.00
IUUC-Osa-086158	Oryza sativa	32.67	1.00e-133	469.00
IUUC-Ola-086822	Oryzias latipes	38.97	0.00e+00	633.00
IUUC-Olu-087741	Ostreococcus lucimarinus	30.37	2.00e-17	80.50
IUUC-Oga-088887	Otolemur garnettii	38.57	8.00e-180	622.00
IUUC-Oar-090110	Ovis aries	37.89	8.00e-173	599.00
IUUC-Pan-092808	Papio anubis	38.53	0.00e+00	660.00
IUUC-Psi-093954	Pelodiscus sinensis	38.58	0.00e+00	652.00
IUUC-Pno-094922	Phaeosphaeria nodorum	36.12	8.00e-158	549.00
IUUC-Ppa-095678	Physcomitrella patens	33.49	8.00e-126	443.00
IUUC-Pfo-097175	Poecilia formosa	39.09	0.00e+00	652.00
IUUC-Pab-098155	Pongo abelii	37.92	0.00e+00	650.00
IUUC-Pop-099635	Populus trichocarpa	33.33	9.00e-138	483.00
IUUC-Pca-100947	Procavia capensis	36.76	4.00e-169	587.00
IUUC-Ppe-101552	Prunus persica	32.85	2.00e-143	502.00
IUUC-Pva-102744	Pteropus vampyrus	35.91	3.00e-159	554.00
IUUC-Pgr-103389	Puccinia graminis	34.73	5.00e-147	513.00
IUUC-Ptt-103953	Puccinia triticina	30.18	2.00e-103	369.00
IUUC-Pte-104079	Pyrenophora teres	35.21	3.00e-148	518.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	35.21	7.00e-149	520.00
IUUC-Rno-105502	Rattus norvegicus	38.15	0.00e+00	654.00
IUUC-Sce-106390	Saccharomyces cerevisiae	34.10	1.00e-154	539.00
IUUC-Sha-107264	Sarcophilus harrisii	35.64	2.00e-67	248.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	34.02	2.00e-158	551.00
IUUC-Spo-108348	Schizosaccharomyces pombe	33.22	4.00e-155	540.00
IUUC-Smo-108982	Selaginella moellendorffii	33.30	1.00e-140	492.00
IUUC-Sit-110304	Setaria italica	33.00	1.00e-138	486.00
IUUC-Sly-111620	Solanum lycopersicum	37.94	8.00e-113	399.00
IUUC-Stu-112877	Solanum tuberosum	32.74	2.00e-142	498.00
IUUC-Sbi-114702	Sorghum bicolor	32.67	4.00e-137	481.00
IUUC-Sre-115129	Sporisorium reilianum	33.30	5.00e-146	510.00
IUUC-Ssc-115931	Sus scrofa	35.20	5.00e-74	270.00
IUUC-Tgu-116787	Taeniopygia guttata	38.99	0.00e+00	656.00
IUUC-Tru-118218	Takifugu rubripes	39.59	0.00e+00	634.00
IUUC-Tsy-119401	Tarsius syrichta	38.97	8.00e-101	360.00
IUUC-Tni-120046	Tetraodon nigroviridis	38.71	3.00e-173	601.00
IUUC-Tca-121685	Theobroma cacao	32.52	6.00e-145	506.00
IUUC-Tre-122154	Trichoderma reesei	35.27	2.00e-151	528.00
IUUC-Tvi-122451	Trichoderma virens	34.36	6.00e-149	520.00
IUUC-Tae-125397	Triticum aestivum	34.42	6.00e-79	287.00
IUUC-Tur-126650	Triticum urartu	32.17	6.00e-120	423.00
IUUC-Tme-127005	Tuber melanosporum	34.36	4.00e-147	514.00
IUUC-Tbe-128102	Tupaia belangeri	39.51	6.00e-108	384.00
IUUC-Ttr-128259	Tursiops truncatus	39.45	1.00e-180	625.00
IUUC-Uma-129511	Ustilago maydis	33.90	7.00e-144	503.00
IUUC-Vda-129833	Verticillium dahliae	31.91	2.00e-131	461.00
IUUC-Vvi-131572	Vitis vinifera	33.98	2.00e-142	498.00
IUUC-Xtr-131776	Xenopus tropicalis	29.67	1.00e-42	166.00
IUUC-Xma-133887	Xiphophorus maculatus	39.09	2.00e-179	622.00
IUUC-Yli-134427	Yarrowia lipolytica	33.56	4.00e-150	524.00
IUUC-Zma-135980	Zea mays	32.52	5.00e-134	470.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence