iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000023286.16	ENSMUST00000024056.9	ENSMUSP00000024056.3
ENSMUSG00000023286.16	ENSMUST00000118192.7	ENSMUSP00000112785.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.60e-28	98.8	28	137

Active Site

Position(s)	Description	Evidence
106	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk..ifhPnvyenGkvClsilk 87
           Rlk+++ +++kdp+++i a+p  + ++ ew++++ Gpe tpYegg+++ ++ fp+++PfkPP++ ++t+  +f++    n+++Clsi +
   Q: 28   RLKQDYLRIKKDPVPYICAEPLPS-NILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPngRFKC----NTRLCLSITD 111
           99**********************.9*******************************************555555....59*******8 PP
   S: 88   .eeekWspalsvesvllsiqsllaep 112
            ++++W+pa+sv+++l+++ s++ e 
   Q: 112  fHPDTWNPAWSVSTILTGLLSFMVEK 137
           89********************9764 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MHQAKALDSA RKMSNNSNKR APTTATQRLK QDYLRIKKDP VPYICAEPLP SNILEWHYVV 60
RGPEMTPYEG GYYHGKLIFP REFPFKPPSI YMITPNGRFK CNTRLCLSIT DFHPDTWNPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCGTCCCC GGAGCGGCCA TCTTGGAGGC TGAGCGGCGG TAGCGGCGGC GAGGCTGCTT 60
GCGGCGGGTG CGGTGGGCCG AGTCCCAGCG CGGGTGCGGC TCACGGCGCG GGCCCCACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002152	Ailuropoda melanoleuca	94.59	1.00e-132	464.00
IUUC-Atr-003156	Amborella trichopoda	54.22	1.00e-53	202.00
IUUC-Apl-004224	Anas platyrhynchos	92.66	8.00e-115	405.00
IUUC-Aca-005049	Anolis carolinensis	88.17	8.00e-127	446.00
IUUC-Aly-006195	Arabidopsis lyrata	53.80	8.00e-50	189.00
IUUC-Ath-006640	Arabidopsis thaliana	53.80	2.00e-50	192.00
IUUC-Ago-007987	Ashbya gossypii	52.02	6.00e-53	200.00
IUUC-Acl-008060	Aspergillus clavatus	55.63	4.00e-43	168.00
IUUC-Afl-008561	Aspergillus flavus	55.63	7.00e-43	167.00
IUUC-Afu-008860	Aspergillus fumigatus	55.63	8.00e-43	167.00
IUUC-Ani-009333	Aspergillus nidulans	54.23	3.00e-42	165.00
IUUC-Ang-009810	Aspergillus niger	56.34	2.00e-43	168.00
IUUC-Aor-010127	Aspergillus oryzae	55.63	7.00e-43	167.00
IUUC-Ate-010362	Aspergillus terreus	55.63	8.00e-43	167.00
IUUC-Ame-010627	Astyanax mexicanus	86.59	4.00e-126	443.00
IUUC-Bgr-012069	Blumeria graminis	51.41	5.00e-40	157.00
IUUC-Bta-012472	Bos taurus	95.37	2.00e-132	464.00
IUUC-Bci-013843	Botrytis cinerea	54.23	6.00e-41	160.00
IUUC-Bdi-014467	Brachypodium distachyon	51.79	9.00e-50	189.00
IUUC-Bol-016116	Brassica oleracea	53.80	2.00e-50	192.00
IUUC-Bra-017799	Brassica rapa	53.50	8.00e-50	189.00
IUUC-Cel-018278	Caenorhabditis elegans	60.24	9.00e-52	196.00
IUUC-Cja-018817	Callithrix jacchus	91.89	2.00e-113	401.00
IUUC-Cfa-020885	Canis familiaris	94.98	5.00e-133	466.00
IUUC-Cpo-022326	Cavia porcellus	96.14	5.00e-142	496.00
IUUC-Cre-022635	Chlamydomonas reinhardtii	58.23	7.00e-55	206.00
IUUC-Csa-023646	Chlorocebus sabaeus	94.59	2.00e-139	488.00
IUUC-Cho-025075	Choloepus hoffmanni	77.92	6.00e-65	239.00
IUUC-Cin-025389	Ciona intestinalis	71.58	1.00e-80	291.00
IUUC-Csv-026315	Ciona savignyi	56.18	4.00e-82	297.00
IUUC-Cgl-026602	Colletotrichum gloeosporioides	54.23	1.00e-42	166.00
IUUC-Cne-026808	Cryptococcus neoformans	50.70	1.00e-41	162.00
IUUC-Dre-028455	Danio rerio	87.26	6.00e-129	452.00
IUUC-Dno-029667	Dasypus novemcinctus	93.05	4.00e-137	480.00
IUUC-Dor-030747	Dipodomys ordii	81.82	6.00e-121	426.00
IUUC-Dse-031231	Dothistroma septosporum	51.41	5.00e-40	157.00
IUUC-Dme-031841	Drosophila melanogaster	51.07	8.00e-76	276.00
IUUC-Ete-032258	Echinops telfairi	84.00	2.00e-121	428.00
IUUC-Eca-033602	Equus caballus	72.31	6.00e-99	353.00
IUUC-Eeu-034443	Erinaceus europaeus	95.02	1.00e-105	375.00
IUUC-Fca-036167	Felis catus	90.04	1.00e-119	422.00
IUUC-Fal-037114	Ficedula albicollis	87.60	9.00e-97	346.00
IUUC-Fox-037957	Fusarium oxysporum	60.00	3.00e-40	158.00
IUUC-Fso-038277	Fusarium solani	54.93	4.00e-43	167.00
IUUC-Gmo-039501	Gadus morhua	81.99	4.00e-108	384.00
IUUC-Ggr-040010	Gaeumannomyces graminis	57.04	1.00e-43	169.00
IUUC-Gga-041257	Gallus gallus	91.51	7.00e-112	396.00
IUUC-Gac-041433	Gasterosteus aculeatus	83.52	1.00e-109	389.00
IUUC-Gma-043529	Glycine max	50.00	4.00e-53	201.00
IUUC-Ggo-044437	Gorilla gorilla	89.57	2.00e-114	404.00
IUUC-Hsa-046693	Homo sapiens	94.21	7.00e-139	486.00
IUUC-Itr-048477	Ictidomys tridecemlineatus	94.59	6.00e-133	466.00
IUUC-Kpa-049391	Komagataella pastoris	54.72	7.00e-42	163.00
IUUC-Lch-049617	Latimeria chalumnae	88.60	1.00e-123	435.00
IUUC-Lpe-050949	Leersia perrieri	50.00	5.00e-48	184.00
IUUC-Loc-052157	Lepisosteus oculatus	89.31	3.00e-121	427.00
IUUC-Lma-053128	Leptosphaeria maculans	55.80	5.00e-42	164.00
IUUC-Laf-054455	Loxodonta africana	94.21	3.00e-123	434.00
IUUC-Mcc-054756	Macaca mulatta	94.59	2.00e-139	488.00
IUUC-Meu-056106	Macropus eugenii	76.28	9.00e-100	356.00
IUUC-Mor-057202	Magnaporthe oryzae	56.34	3.00e-43	168.00
IUUC-Mpo-057349	Magnaporthe poae	56.34	4.00e-43	167.00
IUUC-Mtr-058271	Medicago truncatula	50.87	5.00e-49	187.00
IUUC-Mla-058894	Melampsora laricipopulina	51.80	2.00e-42	164.00
IUUC-Mga-059493	Meleagris gallopavo	91.51	7.00e-112	396.00
IUUC-Mvi-060232	Microbotryum violaceum	48.00	2.00e-41	162.00
IUUC-Mmr-060957	Microcebus murinus	95.37	4.00e-141	493.00
IUUC-Mdo-062141	Monodelphis domestica	93.49	3.00e-130	457.00
IUUC-Mac-064530	Musa acuminata	53.01	5.00e-50	190.00
IUUC-Mpu-065902	Mustela putorius furo	94.98	3.00e-133	467.00
IUUC-Mlu-068008	Myotis lucifugus	94.98	4.00e-132	463.00
IUUC-Nfi-068515	Neosartorya fischeri	55.63	4.00e-43	168.00
IUUC-Ncr-068755	Neurospora crassa	54.93	6.00e-42	164.00
IUUC-Opr-071201	Ochotona princeps	89.55	5.00e-87	313.00
IUUC-Ont-071311	Oreochromis niloticus	83.52	2.00e-108	385.00
IUUC-Oan-073310	Ornithorhynchus anatinus	90.35	2.00e-129	454.00
IUUC-Ocu-074514	Oryctolagus cuniculus	93.44	4.00e-138	483.00
IUUC-Oba-075200	Oryza barthii	50.00	3.00e-48	184.00
IUUC-Obr-076396	Oryza brachyantha	49.18	3.00e-49	187.00
IUUC-Ogl-077398	Oryza glaberrima	50.00	4.00e-48	184.00
IUUC-Ogu-078362	Oryza glumaepatula	50.00	3.00e-48	184.00
IUUC-Oin-079625	Oryza indica	50.00	3.00e-48	184.00
IUUC-Olo-080620	Oryza longistaminata	44.85	4.00e-29	121.00
IUUC-Ome-081187	Oryza meridionalis	50.00	4.00e-48	184.00
IUUC-Oni-082271	Oryza nivara	50.00	5.00e-48	184.00
IUUC-Opu-083487	Oryza punctata	49.40	3.00e-47	181.00
IUUC-Oru-085263	Oryza rufipogon	50.00	3.00e-48	184.00
IUUC-Osa-085694	Oryza sativa	50.00	3.00e-48	184.00
IUUC-Ola-086450	Oryzias latipes	84.94	1.00e-116	412.00
IUUC-Olu-087733	Ostreococcus lucimarinus	42.06	1.00e-25	109.00
IUUC-Oga-088054	Otolemur garnettii	89.09	9.00e-126	442.00
IUUC-Oar-089486	Ovis aries	95.00	8.00e-133	466.00
IUUC-Pan-092633	Papio anubis	94.59	2.00e-139	488.00
IUUC-Psi-093165	Pelodiscus sinensis	84.78	3.00e-36	143.00
IUUC-Pno-095025	Phaeosphaeria nodorum	56.52	3.00e-43	168.00
IUUC-Ppa-095641	Physcomitrella patens	56.96	3.00e-54	204.00
IUUC-Pfo-096423	Poecilia formosa	85.44	7.00e-104	369.00
IUUC-Pab-097771	Pongo abelii	94.98	7.00e-140	489.00
IUUC-Pop-099714	Populus trichocarpa	51.74	2.00e-53	202.00
IUUC-Pca-100493	Procavia capensis	83.72	2.00e-80	291.00
IUUC-Ppe-102054	Prunus persica	50.58	2.00e-52	198.00
IUUC-Pva-102224	Pteropus vampyrus	91.89	3.00e-126	444.00
IUUC-Pgr-103530	Puccinia graminis	50.64	2.00e-46	178.00
IUUC-Ptt-103776	Puccinia triticina	50.00	4.00e-45	174.00
IUUC-Pte-104166	Pyrenophora teres	54.35	6.00e-42	164.00
IUUC-Pyt-104570	Pyrenophora triticirepentis	54.35	1.00e-41	163.00
IUUC-Rno-105593	Rattus norvegicus	98.89	4.00e-142	496.00
IUUC-Sce-106212	Saccharomyces cerevisiae	59.12	2.00e-52	198.00
IUUC-Sha-106767	Sarcophilus harrisii	93.44	4.00e-129	453.00
IUUC-Sja-107907	Schizosaccharomyces japonicus	48.81	3.00e-48	184.00
IUUC-Spo-108094	Schizosaccharomyces pombe	53.16	4.00e-48	184.00
IUUC-Ssl-108556	Sclerotinia sclerotiorum	54.23	2.00e-41	162.00
IUUC-Smo-108965	Selaginella moellendorffii	51.69	1.00e-54	205.00
IUUC-Sit-110407	Setaria italica	54.88	6.00e-51	193.00
IUUC-Sly-111642	Solanum lycopersicum	49.72	1.00e-48	186.00
IUUC-Stu-112336	Solanum tuberosum	48.15	1.00e-47	182.00
IUUC-Sbi-114327	Sorghum bicolor	54.88	1.00e-50	192.00
IUUC-Sre-115170	Sporisorium reilianum	54.14	4.00e-42	164.00
IUUC-Ssc-116385	Sus scrofa	94.21	4.00e-131	460.00
IUUC-Tgu-117041	Taeniopygia guttata	86.87	4.00e-102	363.00
IUUC-Tru-117697	Takifugu rubripes	85.88	9.00e-112	395.00
IUUC-Tsy-119024	Tarsius syrichta	84.56	7.00e-126	442.00
IUUC-Tni-120466	Tetraodon nigroviridis	83.40	8.00e-110	389.00
IUUC-Tca-121569	Theobroma cacao	48.42	1.00e-50	192.00
IUUC-Tre-121882	Trichoderma reesei	56.34	4.00e-43	167.00
IUUC-Tvi-122466	Trichoderma virens	55.63	8.00e-43	167.00
IUUC-Tae-124797	Triticum aestivum	54.60	6.00e-51	193.00
IUUC-Tur-126536	Triticum urartu	55.00	1.00e-50	192.00
IUUC-Tme-127051	Tuber melanosporum	57.04	7.00e-45	174.00
IUUC-Tbe-128095	Tupaia belangeri	93.47	4.00e-95	340.00
IUUC-Ttr-128466	Tursiops truncatus	94.59	1.00e-131	461.00
IUUC-Uma-129383	Ustilago maydis	53.50	1.00e-41	162.00
IUUC-Vda-130013	Verticillium dahliae	55.22	6.00e-41	160.00
IUUC-Vvi-131251	Vitis vinifera	53.16	3.00e-47	181.00
IUUC-Xtr-132408	Xenopus tropicalis	91.12	1.00e-141	494.00
IUUC-Xma-133893	Xiphophorus maculatus	85.44	5.00e-104	370.00
IUUC-Yli-134618	Yarrowia lipolytica	58.78	1.00e-50	192.00
IUUC-Zma-135216	Zea mays	54.27	2.00e-50	192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence