iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mla-059061

Ensembl Protein ID

EGG13148

UniProt Accession

F4R3L0; F4R3L0_MELLP

Genbank Protein ID

EGG13148.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 39 kDa subunit homolog

Genbank Nucleotide ID

GL883090

Gene Name

TIF34; MELLADRAFT_41438

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MELLADRAFT_41438	EGG13148	EGG13148

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-25	86.1	50	88
UBD/Beta-Prp	3.50e-42	144.3	6	250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++ v++++  s   +lvsGs D+++++W++ tg +lk
   Q: 50   GHNGTVWSVDVdSKsEYLVSGSADNSMRLWRVATGECLK 88
           8**********9556**********************97 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee................. 131
           lsghe   t+vk++++g++l ++s+D++i+vw   +g+ + t++gh+ +v+s++++ ++++lvsGs+d+  r+w + tg+cl++                 
   Q: 6    LSGHERSLTQVKYNREGDLLFSCSKDHIINVWYTHNGERLGTYNGHNGTVWSVDVDSKSEYLVSGSADNSMRLWRVATGECLKAwefptavkrvswsedds 106
           68999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 132  ..................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsg 198
                                             ++s+  +  ++v+++  +++l++G+ +++v lWd ++g+ +   +++h + ++ l+++ +++++v+ 
   Q: 107  kvtlvteqrmghqgavrvfeitrdgspqsdeptlMFSPVGSKAMVVAFSFLDKYLITGHENGKVALWDAESGEEVISREKNHLGLITDLQLSADRTYFVTS 207
           99999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 199  sldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs 241
           s+d++ +l++ +t + ++t+++ +++ +sv++ p + +l++g+
   Q: 208  SKDKSARLYNTRTLDLIKTYQDPQTPLNSVALIPGKPYLLVGG 250
           9999999999999999999999999999999999999999887 PP

Organism

Melampsora laricipopulina

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILLSGHE RSLTQVKYNR EGDLLFSCSK DHIINVWYTH NGERLGTYNG HNGTVWSVDV 60
DSKSEYLVSG SADNSMRLWR VATGECLKAW EFPTAVKRVS WSEDDSKVTL VTEQRMGHQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCAACTTT GACTCACCAC AAGTTTTAGA AAAAACCGAT ACCAAACCGA ATACATCCAT 60
CCATCAATCG ATTATCGGTT CACGTTCATT GTATCAATCA ATCAAAAGAA AATTCATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0022627--C:cytosolic small ribosomal subunit
GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0071540--C:eukaryotic translation initiation factor 3 complex, eIF3e
GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0043614--C:multi-eIF complex
GO:0034399--C:nuclear periphery
GO:0003743--F:translation initiation factor activity
GO:0071470--P:cellular response to osmotic stress
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation
GO:0002188--P:translation reinitiation

KEGG

mlr:MELLADRAFT_41438

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	42.62	1.00e-25	108.00
IUUC-Aml-001321	Ailuropoda melanoleuca	48.44	6.00e-85	305.00
IUUC-Atr-002468	Amborella trichopoda	44.71	8.00e-40	154.00
IUUC-Apl-003841	Anas platyrhynchos	47.81	4.00e-86	309.00
IUUC-Aca-005123	Anolis carolinensis	47.98	2.00e-86	310.00
IUUC-Aly-006532	Arabidopsis lyrata	43.29	4.00e-75	272.00
IUUC-Ath-007094	Arabidopsis thaliana	43.60	1.00e-76	277.00
IUUC-Ago-008000	Ashbya gossypii	45.88	2.00e-87	313.00
IUUC-Acl-008098	Aspergillus clavatus	53.49	5.00e-106	375.00
IUUC-Afl-008494	Aspergillus flavus	54.60	2.00e-110	390.00
IUUC-Afu-009080	Aspergillus fumigatus	53.20	4.00e-106	375.00
IUUC-Ani-009230	Aspergillus nidulans	56.18	4.00e-109	385.00
IUUC-Aor-010114	Aspergillus oryzae	54.60	2.00e-110	390.00
IUUC-Ate-010285	Aspergillus terreus	56.76	2.00e-110	389.00
IUUC-Ame-011534	Astyanax mexicanus	47.85	1.00e-86	311.00
IUUC-Bgr-012121	Blumeria graminis	52.16	5.00e-99	352.00
IUUC-Bta-013143	Bos taurus	48.60	1.00e-85	307.00
IUUC-Bci-013950	Botrytis cinerea	55.73	4.00e-109	385.00
IUUC-Bdi-015019	Brachypodium distachyon	43.87	1.00e-79	287.00
IUUC-Bol-015709	Brassica oleracea	43.43	8.00e-75	272.00
IUUC-Bra-017760	Brassica rapa	43.43	6.00e-75	273.00
IUUC-Cel-018226	Caenorhabditis elegans	38.75	1.00e-66	244.00
IUUC-Cja-019741	Callithrix jacchus	48.29	2.00e-85	306.00
IUUC-Cfa-021204	Canis familiaris	48.12	1.00e-84	304.00
IUUC-Cpo-021661	Cavia porcellus	48.12	9.00e-85	304.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	38.34	6.00e-69	252.00
IUUC-Csa-024038	Chlorocebus sabaeus	48.29	2.00e-85	306.00
IUUC-Cin-025597	Ciona intestinalis	46.30	3.00e-89	319.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	55.42	2.00e-104	370.00
IUUC-Cne-026838	Cryptococcus neoformans	54.71	3.00e-112	395.00
IUUC-Cme-027304	Cyanidioschyzon merolae	42.28	8.00e-68	248.00
IUUC-Dre-028567	Danio rerio	46.42	5.00e-85	305.00
IUUC-Dno-029171	Dasypus novemcinctus	48.75	2.00e-85	307.00
IUUC-Dor-030257	Dipodomys ordii	36.93	5.00e-31	126.00
IUUC-Dse-031191	Dothistroma septosporum	54.38	8.00e-100	354.00
IUUC-Dme-031879	Drosophila melanogaster	45.68	3.00e-86	309.00
IUUC-Ete-032336	Echinops telfairi	41.55	1.00e-40	157.00
IUUC-Eca-033259	Equus caballus	48.12	1.00e-84	304.00
IUUC-Eeu-035153	Erinaceus europaeus	41.55	1.00e-23	101.00
IUUC-Fca-036489	Felis catus	48.12	1.00e-84	304.00
IUUC-Fal-037485	Ficedula albicollis	47.81	2.00e-86	310.00
IUUC-Fox-037860	Fusarium oxysporum	51.18	1.00e-100	357.00
IUUC-Fso-038188	Fusarium solani	50.59	7.00e-97	344.00
IUUC-Gmo-039311	Gadus morhua	46.56	2.00e-84	303.00
IUUC-Ggr-040045	Gaeumannomyces graminis	54.49	5.00e-107	378.00
IUUC-Gga-040645	Gallus gallus	46.81	1.00e-84	304.00
IUUC-Gac-042086	Gasterosteus aculeatus	46.11	1.00e-83	300.00
IUUC-Gma-043246	Glycine max	44.17	4.00e-79	285.00
IUUC-Ggo-045578	Gorilla gorilla	48.29	2.00e-85	306.00
IUUC-Hsa-046734	Homo sapiens	48.29	2.00e-85	306.00
IUUC-Hvu-047553	Hordeum vulgare	43.56	2.00e-78	283.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	47.81	2.00e-84	303.00
IUUC-Kpa-049325	Komagataella pastoris	49.54	2.00e-95	340.00
IUUC-Lch-049620	Latimeria chalumnae	46.00	6.00e-77	278.00
IUUC-Lpe-051338	Leersia perrieri	41.90	3.00e-74	270.00
IUUC-Loc-052094	Lepisosteus oculatus	43.93	2.00e-72	263.00
IUUC-Lma-053047	Leptosphaeria maculans	54.63	1.00e-103	367.00
IUUC-Laf-053801	Loxodonta africana	47.94	1.00e-82	297.00
IUUC-Mcc-055498	Macaca mulatta	41.74	4.00e-64	236.00
IUUC-Meu-056729	Macropus eugenii	45.20	1.00e-75	274.00
IUUC-Mor-057025	Magnaporthe oryzae	54.49	1.00e-104	370.00
IUUC-Mpo-057511	Magnaporthe poae	54.80	1.00e-106	377.00
IUUC-Mtr-058051	Medicago truncatula	43.87	4.00e-78	282.00
IUUC-Mga-059229	Meleagris gallopavo	47.20	9.00e-84	301.00
IUUC-Mvi-060399	Microbotryum violaceum	66.57	1.00e-133	467.00
IUUC-Mmr-060764	Microcebus murinus	48.91	2.00e-86	310.00
IUUC-Mdo-062088	Monodelphis domestica	48.45	4.00e-84	302.00
IUUC-Mmu-064304	Mus musculus	48.60	9.00e-86	308.00
IUUC-Mac-065520	Musa acuminata	44.55	1.00e-77	281.00
IUUC-Mpu-066340	Mustela putorius furo	48.12	1.00e-84	304.00
IUUC-Mlu-067111	Myotis lucifugus	48.44	2.00e-85	306.00
IUUC-Nfi-068478	Neosartorya fischeri	53.20	4.00e-106	375.00
IUUC-Ncr-068820	Neurospora crassa	55.73	4.00e-105	372.00
IUUC-Nle-069903	Nomascus leucogenys	48.12	4.00e-85	305.00
IUUC-Opr-070221	Ochotona princeps	47.66	7.00e-83	298.00
IUUC-Ont-071765	Oreochromis niloticus	46.42	7.00e-86	308.00
IUUC-Oan-073660	Ornithorhynchus anatinus	46.90	6.00e-70	255.00
IUUC-Ocu-074039	Oryctolagus cuniculus	48.12	9.00e-85	304.00
IUUC-Oba-075395	Oryza barthii	39.57	1.00e-66	244.00
IUUC-Obr-076334	Oryza brachyantha	41.72	2.00e-72	263.00
IUUC-Ogl-077751	Oryza glaberrima	43.87	4.00e-80	289.00
IUUC-Ogu-078207	Oryza glumaepatula	44.48	3.00e-81	292.00
IUUC-Oin-079878	Oryza indica	44.48	5.00e-81	292.00
IUUC-Olo-080677	Oryza longistaminata	37.89	2.00e-71	260.00
IUUC-Ome-081228	Oryza meridionalis	37.08	1.00e-42	164.00
IUUC-Oni-082411	Oryza nivara	38.34	2.00e-63	233.00
IUUC-Opu-083136	Oryza punctata	43.56	7.00e-80	288.00
IUUC-Oru-084916	Oryza rufipogon	43.28	4.00e-80	289.00
IUUC-Osa-085454	Oryza sativa	44.48	5.00e-81	292.00
IUUC-Ola-087053	Oryzias latipes	46.73	8.00e-85	305.00
IUUC-Olu-087602	Ostreococcus lucimarinus	42.55	2.00e-78	283.00
IUUC-Oga-088154	Otolemur garnettii	48.12	5.00e-85	305.00
IUUC-Oar-089915	Ovis aries	48.44	7.00e-85	305.00
IUUC-Ptr-091124	Pan troglodytes	41.38	2.00e-62	230.00
IUUC-Pan-092035	Papio anubis	48.29	2.00e-85	306.00
IUUC-Psi-094096	Pelodiscus sinensis	44.55	5.00e-47	178.00
IUUC-Pno-094988	Phaeosphaeria nodorum	50.93	1.00e-88	317.00
IUUC-Ppa-095536	Physcomitrella patens	47.02	6.00e-83	298.00
IUUC-Pfo-096101	Poecilia formosa	46.11	4.00e-84	302.00
IUUC-Pab-097726	Pongo abelii	48.29	2.00e-85	306.00
IUUC-Pop-099617	Populus trichocarpa	44.48	4.00e-78	282.00
IUUC-Pca-101014	Procavia capensis	48.60	7.00e-86	308.00
IUUC-Ppe-101320	Prunus persica	44.17	7.00e-78	281.00
IUUC-Pva-102789	Pteropus vampyrus	45.17	6.00e-76	275.00
IUUC-Pgr-103479	Puccinia graminis	87.50	0.00e+00	637.00
IUUC-Ptt-103981	Puccinia triticina	86.90	0.00e+00	633.00
IUUC-Pte-104278	Pyrenophora teres	53.40	1.00e-99	353.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	53.40	1.00e-99	353.00
IUUC-Rno-105867	Rattus norvegicus	44.65	8.00e-70	254.00
IUUC-Sce-106251	Saccharomyces cerevisiae	46.22	2.00e-88	316.00
IUUC-Sha-107039	Sarcophilus harrisii	48.45	4.00e-84	302.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	53.68	2.00e-105	373.00
IUUC-Spo-108314	Schizosaccharomyces pombe	53.99	2.00e-105	373.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	55.11	3.00e-108	382.00
IUUC-Smo-108728	Selaginella moellendorffii	45.37	2.00e-80	290.00
IUUC-Sit-110801	Setaria italica	43.87	4.00e-81	292.00
IUUC-Sly-111326	Solanum lycopersicum	44.58	4.00e-79	285.00
IUUC-Stu-112458	Solanum tuberosum	44.79	5.00e-79	285.00
IUUC-Sbi-114063	Sorghum bicolor	43.56	2.00e-80	290.00
IUUC-Sre-115096	Sporisorium reilianum	61.38	2.00e-114	403.00
IUUC-Ssc-116080	Sus scrofa	48.60	1.00e-85	307.00
IUUC-Tgu-116988	Taeniopygia guttata	47.81	4.00e-86	309.00
IUUC-Tru-118766	Takifugu rubripes	46.42	6.00e-85	305.00
IUUC-Tni-120197	Tetraodon nigroviridis	46.42	2.00e-85	306.00
IUUC-Tca-121316	Theobroma cacao	45.09	3.00e-80	289.00
IUUC-Tre-122097	Trichoderma reesei	52.07	3.00e-102	362.00
IUUC-Tvi-122442	Trichoderma virens	54.18	5.00e-102	362.00
IUUC-Tae-125800	Triticum aestivum	43.56	1.00e-78	284.00
IUUC-Tur-126334	Triticum urartu	36.50	5.00e-58	216.00
IUUC-Tme-127038	Tuber melanosporum	57.01	6.00e-110	388.00
IUUC-Ttr-128659	Tursiops truncatus	45.48	2.00e-67	246.00
IUUC-Uma-129464	Ustilago maydis	61.67	1.00e-114	404.00
IUUC-Vda-129841	Verticillium dahliae	57.28	9.00e-108	380.00
IUUC-Vvi-131076	Vitis vinifera	43.87	3.00e-78	283.00
IUUC-Xtr-132395	Xenopus tropicalis	47.35	3.00e-84	302.00
IUUC-Xma-133383	Xiphophorus maculatus	46.11	5.00e-84	302.00
IUUC-Yli-134586	Yarrowia lipolytica	47.38	2.00e-81	293.00
IUUC-Zma-135904	Zea mays	43.56	2.00e-80	290.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence