iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091137

UUCD1 version

UUC-PaT-00188

Ensembl Protein ID

ENSPTRP00000007251.2

UniProt Accession

H2Q4M6; H2Q4M6_PANTR

Genbank Protein ID

JAA02758.1; JAA21846.1; JAA26010.1

Protein Name

Baculoviral IAP repeat containing 2

Genbank Nucleotide ID

AACZ03081095; GABF01000299; GABD01007090

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000004213.2	ENSPTRT00000007859.2	ENSPTRP00000007251.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.84	0.00e+00	1179.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MHKTASQRLF PGPSYQNIKS IMEDSTILSD WTNSNKQKMK YDFSCELYRM STYSTFPAGV 60
PVSERSLARA GFYYTGVNDK VKCFCCGLML DNWKLGDSPI QKHKQLYPSC SFIQNLVSAS 120

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Nucleotide Sequence
(Fasta)

GGATGGGGCG GCGGGCTTCG GGAGCGCCCG GGCTGATCCG AGCCGAGCGG GCCGTATCTC 60
CTTGTCGGCT CCGCTGATTC CCGGCTCTGA GGAGGCCTCT AGGCAGCCGC GCAGCTTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0043027--F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:1990001--P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070266--P:necroptotic process
GO:0060546--P:negative regulation of necroptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

KEGG

ptr:451508

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	88.08	0.00e+00	1077.00
IUUC-Aca-004515	Anolis carolinensis	69.44	0.00e+00	775.00
IUUC-Aly-006460	Arabidopsis lyrata	38.89	1.00e-09	56.60
IUUC-Afl-008648	Aspergillus flavus	31.03	1.00e-14	75.50
IUUC-Ang-009667	Aspergillus niger	30.67	2.00e-12	68.20
IUUC-Ame-011877	Astyanax mexicanus	55.17	0.00e+00	655.00
IUUC-Bgr-012051	Blumeria graminis	33.76	2.00e-12	68.20
IUUC-Bta-012450	Bos taurus	88.79	0.00e+00	961.00
IUUC-Bci-013905	Botrytis cinerea	35.00	1.00e-16	81.60
IUUC-Bol-015478	Brassica oleracea	33.05	4.00e-10	62.80
IUUC-Bra-017001	Brassica rapa	33.05	3.00e-10	63.20
IUUC-Cja-018895	Callithrix jacchus	95.64	0.00e+00	1129.00
IUUC-Cfa-020419	Canis familiaris	88.21	0.00e+00	1080.00
IUUC-Cpo-022048	Cavia porcellus	88.35	0.00e+00	1072.00
IUUC-Cho-024277	Choloepus hoffmanni	86.59	0.00e+00	1028.00
IUUC-Cin-025521	Ciona intestinalis	30.85	5.00e-76	278.00
IUUC-Dre-028647	Danio rerio	54.95	0.00e+00	643.00
IUUC-Dno-029509	Dasypus novemcinctus	82.23	0.00e+00	958.00
IUUC-Dor-030796	Dipodomys ordii	74.48	4.00e-99	355.00
IUUC-Ete-032768	Echinops telfairi	69.01	0.00e+00	731.00
IUUC-Eca-033393	Equus caballus	92.99	0.00e+00	1088.00
IUUC-Eeu-035114	Erinaceus europaeus	85.44	0.00e+00	1016.00
IUUC-Fca-036034	Felis catus	87.08	0.00e+00	1048.00
IUUC-Gmo-038477	Gadus morhua	55.57	3.00e-178	618.00
IUUC-Gga-040601	Gallus gallus	71.31	0.00e+00	845.00
IUUC-Gac-041467	Gasterosteus aculeatus	56.27	0.00e+00	629.00
IUUC-Ggo-044857	Gorilla gorilla	99.51	0.00e+00	1175.00
IUUC-Hsa-045769	Homo sapiens	99.84	0.00e+00	1179.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	91.37	0.00e+00	1097.00
IUUC-Lch-050259	Latimeria chalumnae	61.14	0.00e+00	723.00
IUUC-Loc-052169	Lepisosteus oculatus	54.63	6.00e-172	597.00
IUUC-Laf-053449	Loxodonta africana	86.59	0.00e+00	1044.00
IUUC-Meu-056241	Macropus eugenii	69.78	0.00e+00	710.00
IUUC-Mga-059947	Meleagris gallopavo	71.34	0.00e+00	849.00
IUUC-Mdo-062352	Monodelphis domestica	77.53	0.00e+00	929.00
IUUC-Mmu-064340	Mus musculus	83.06	0.00e+00	1004.00
IUUC-Mpu-065890	Mustela putorius furo	88.42	0.00e+00	979.00
IUUC-Mlu-068077	Myotis lucifugus	90.38	0.00e+00	1079.00
IUUC-Nfi-068591	Neosartorya fischeri	31.06	2.00e-13	71.20
IUUC-Nle-070081	Nomascus leucogenys	97.41	0.00e+00	1167.00
IUUC-Opr-070561	Ochotona princeps	83.98	0.00e+00	992.00
IUUC-Ont-071776	Oreochromis niloticus	54.69	0.00e+00	641.00
IUUC-Oan-073604	Ornithorhynchus anatinus	76.40	0.00e+00	896.00
IUUC-Ocu-073963	Oryctolagus cuniculus	91.12	0.00e+00	1060.00
IUUC-Ogu-078452	Oryza glumaepatula	47.73	3.00e-07	49.30
IUUC-Ome-081435	Oryza meridionalis	45.65	1.00e-06	47.40
IUUC-Oni-082044	Oryza nivara	43.64	1.00e-09	57.40
IUUC-Opu-084085	Oryza punctata	41.67	1.00e-06	47.00
IUUC-Oru-085060	Oryza rufipogon	46.51	8.00e-07	48.10
IUUC-Ola-086446	Oryzias latipes	52.56	6.00e-174	603.00
IUUC-Oga-087976	Otolemur garnettii	92.72	0.00e+00	1108.00
IUUC-Oar-090097	Ovis aries	88.78	0.00e+00	1086.00
IUUC-Pan-092673	Papio anubis	98.38	0.00e+00	1172.00
IUUC-Psi-092992	Pelodiscus sinensis	71.15	0.00e+00	837.00
IUUC-Pma-094277	Petromyzon marinus	38.13	9.00e-113	400.00
IUUC-Pfo-096790	Poecilia formosa	53.80	3.00e-178	618.00
IUUC-Pab-098734	Pongo abelii	99.50	0.00e+00	1132.00
IUUC-Pop-098944	Populus trichocarpa	42.59	5.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	73.36	7.00e-178	616.00
IUUC-Pva-102788	Pteropus vampyrus	91.76	0.00e+00	1097.00
IUUC-Rno-105026	Rattus norvegicus	81.41	0.00e+00	967.00
IUUC-Sha-107229	Sarcophilus harrisii	71.77	0.00e+00	852.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	33.56	1.00e-15	79.00
IUUC-Ssc-115804	Sus scrofa	88.26	0.00e+00	1050.00
IUUC-Tru-117620	Takifugu rubripes	53.54	0.00e+00	626.00
IUUC-Tni-119683	Tetraodon nigroviridis	54.12	2.00e-180	625.00
IUUC-Tbe-127523	Tupaia belangeri	91.91	0.00e+00	1117.00
IUUC-Ttr-128954	Tursiops truncatus	88.39	0.00e+00	1058.00
IUUC-Vpa-130441	Vicugna pacos	90.29	0.00e+00	1086.00
IUUC-Xtr-132031	Xenopus tropicalis	57.96	0.00e+00	655.00
IUUC-Xma-132984	Xiphophorus maculatus	54.40	0.00e+00	626.00
IUUC-Yli-134629	Yarrowia lipolytica	32.79	4.00e-16	79.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence