iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000018535.1	ENSONIT00000023354.1	ENSONIP00000023334.1
ENSONIG00000018535.1	ENSONIT00000023355.1	ENSONIP00000023335.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.30e-14	52.6	825	875

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ + ++ eL+l++Gdv+++   ++  +gW+kg      + G fP+ +ve+
   Q: 825  IARYDFCSRDTRELSLQQGDVITIY--TKMPNGWWKG--VVGDRVGWFPSTYVEE 875
           688*********************8..999*******..7999**********86 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MEYWRQCAMW LISCNVLPAN HRVTADTAQV FDLAQTLRDG VLLCQLLNNL RPHTINLKEI 60
NLRPQMSQFL CLKNIRTFLA SCCDVFGMKK SDLFEAFDLF DVRDFGKVMD TLSKLSHTTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGTAGCGG CTCGTCTGTC CTCCAGAGGC GATGCTGGAG TTTGAAGAGA CATGCGGATG 60
GCTCAGGACG CAGCTTCTTC CCCATGCCGT GCACAGACTT AATAAGCGGA CAAAGTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR003096--SM22_calponin

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00888--SM22CALPONIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028199	Danio rerio	70.72	0.00e+00	1230.00
IUUC-Gac-042533	Gasterosteus aculeatus	81.39	0.00e+00	1476.00
IUUC-Pfo-096153	Poecilia formosa	83.24	0.00e+00	1485.00
IUUC-Tru-117884	Takifugu rubripes	78.28	0.00e+00	1431.00
IUUC-Tsy-119429	Tarsius syrichta	59.24	0.00e+00	904.00
IUUC-Tni-120835	Tetraodon nigroviridis	76.07	0.00e+00	1365.00
IUUC-Xma-134091	Xiphophorus maculatus	85.75	0.00e+00	1569.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence